CN100431634C - 干粉气溶胶化吸入器 - Google Patents
干粉气溶胶化吸入器 Download PDFInfo
- Publication number
- CN100431634C CN100431634C CNB2005100386811A CN200510038681A CN100431634C CN 100431634 C CN100431634 C CN 100431634C CN B2005100386811 A CNB2005100386811 A CN B2005100386811A CN 200510038681 A CN200510038681 A CN 200510038681A CN 100431634 C CN100431634 C CN 100431634C
- Authority
- CN
- China
- Prior art keywords
- dry powder
- suction nozzle
- eddy current
- internal diameter
- main body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000843 powder Substances 0.000 title claims abstract description 92
- 230000035772 mutation Effects 0.000 claims description 5
- 239000003814 drug Substances 0.000 abstract description 17
- 239000000443 aerosol Substances 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 5
- 210000002345 respiratory system Anatomy 0.000 abstract description 5
- 206010011409 Cross infection Diseases 0.000 abstract description 4
- 206010029803 Nosocomial infection Diseases 0.000 abstract description 4
- 238000007664 blowing Methods 0.000 abstract description 2
- 239000008187 granular material Substances 0.000 abstract 1
- 210000003456 pulmonary alveoli Anatomy 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 description 24
- 229940079593 drug Drugs 0.000 description 3
- 210000002200 mouth mucosa Anatomy 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- 238000010276 construction Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
- A61M15/0015—Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100386811A CN100431634C (zh) | 2005-04-04 | 2005-04-04 | 干粉气溶胶化吸入器 |
| EP06722039A EP1872817B1 (en) | 2005-04-04 | 2006-03-13 | Dry powder aerosolizing inhaler |
| US11/887,755 US8978645B2 (en) | 2005-04-04 | 2006-03-13 | Dry powder aerosolized inhaler |
| JP2008503352A JP5086988B2 (ja) | 2005-04-04 | 2006-03-13 | 乾粉エアロゾル化吸入器 |
| PCT/CN2006/000381 WO2006105709A1 (en) | 2005-04-04 | 2006-03-13 | Dry powder aerosolizing inhaler |
| AT06722039T ATE539785T1 (de) | 2005-04-04 | 2006-03-13 | Aerosolbildender trockenpulverinhalator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100386811A CN100431634C (zh) | 2005-04-04 | 2005-04-04 | 干粉气溶胶化吸入器 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1666788A CN1666788A (zh) | 2005-09-14 |
| CN100431634C true CN100431634C (zh) | 2008-11-12 |
Family
ID=35038170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100386811A Expired - Fee Related CN100431634C (zh) | 2005-04-04 | 2005-04-04 | 干粉气溶胶化吸入器 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8978645B2 (enExample) |
| EP (1) | EP1872817B1 (enExample) |
| JP (1) | JP5086988B2 (enExample) |
| CN (1) | CN100431634C (enExample) |
| AT (1) | ATE539785T1 (enExample) |
| WO (1) | WO2006105709A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| SI1494732T1 (sl) | 2002-03-20 | 2008-08-31 | Mannking Corp | Inhalacijski aparat |
| KR101273120B1 (ko) | 2004-08-20 | 2013-06-13 | 맨카인드 코포레이션 | 다이케토피페라진 합성의 촉매 작용 |
| BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
| KR101486829B1 (ko) | 2005-09-14 | 2015-01-29 | 맨카인드 코포레이션 | 결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법 |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| JP5570996B2 (ja) | 2007-12-14 | 2014-08-13 | エアロデザインズ インコーポレイテッド | エアロゾル化可能な食料品の送達 |
| TWI677355B (zh) | 2008-06-13 | 2019-11-21 | 美商曼凱公司 | 用於藥物傳輸之乾粉吸入器及系統 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2421385T3 (es) * | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2676695A3 (en) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| MY186975A (en) | 2009-06-12 | 2021-08-26 | Mannkind Corp | Diketopiperazine microparticles with defined specific surface areas |
| WO2011013003A2 (en) | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| US9016147B2 (en) | 2009-11-03 | 2015-04-28 | Mannkind Corporation | Apparatus and method for simulating inhalation efforts |
| MX359281B (es) | 2010-06-21 | 2018-09-21 | Mannkind Corp | Sistema y metodos para suministrar un farmaco en polvo seco. |
| CN102553040B (zh) * | 2010-12-17 | 2014-07-02 | 陈庆堂 | 滤出药粉吸入器 |
| AU2012212866B2 (en) | 2011-01-31 | 2016-09-15 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| US8925726B2 (en) | 2011-04-01 | 2015-01-06 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| CA2852536A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
| CA2878457C (en) | 2012-07-12 | 2021-01-19 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
| EP2970149B1 (en) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Microcrystalline diketopiperazine compositions and methods |
| EP3021834A1 (en) | 2013-07-18 | 2016-05-25 | MannKind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
| CN105517607A (zh) | 2013-08-05 | 2016-04-20 | 曼金德公司 | 吹入设备和方法 |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| CN106075677B (zh) * | 2016-08-08 | 2022-06-10 | 中山市美捷时包装制品有限公司 | 一种干粉吸入装置的促动机构 |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| JP7209715B2 (ja) * | 2017-11-23 | 2023-01-20 | チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド | 新型乾燥粉末吸入装置 |
| EP3772252B1 (en) * | 2018-03-26 | 2022-05-04 | Philip Morris Products S.A. | Inhaler with apertured porous support element |
| CN115702961A (zh) * | 2021-08-03 | 2023-02-17 | 上海臣邦医药科技股份有限公司 | 一种单剂量可抛弃型粉雾剂装置 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004129915A (ja) * | 2002-10-11 | 2004-04-30 | Otsuka Pharmaceut Co Ltd | 粉末吸入器 |
| JP2004329678A (ja) * | 2003-05-09 | 2004-11-25 | Otsuka Pharmaceut Co Ltd | 粉末吸入器 |
| CN1189223C (zh) * | 1998-08-14 | 2005-02-16 | 尼科-普夫公司 | 吸入器 |
| CN2794531Y (zh) * | 2005-04-04 | 2006-07-12 | 陈庆堂 | 干粉气溶胶化吸入器 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI69963C (fi) * | 1984-10-04 | 1986-09-12 | Orion Yhtymae Oy | Doseringsanordning |
| US5201308A (en) * | 1990-02-14 | 1993-04-13 | Newhouse Michael T | Powder inhaler |
| GB9015522D0 (en) * | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| DE4211475A1 (de) | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| US5239993A (en) * | 1992-08-26 | 1993-08-31 | Glaxo Inc. | Dosage inhalator providing optimized compound inhalation trajectory |
| US5349947A (en) * | 1993-07-15 | 1994-09-27 | Newhouse Michael T | Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow |
| KR100419037B1 (ko) * | 1994-03-07 | 2004-06-12 | 넥타르 테라퓨틱스 | 폐를통한인슐린의전달방법및그조성물 |
| FR2718968B1 (fr) * | 1994-04-20 | 1996-07-26 | Valois Sa | Insert délimitant une chambre de dosage d'un inhalateur. |
| DE59605366D1 (de) * | 1995-12-07 | 2000-07-06 | Jago Pharma Ag Muttenz | Inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers |
| JP3328131B2 (ja) | 1996-03-15 | 2002-09-24 | 株式会社ユニシアジェックス | 吸入式投薬器 |
| GB9626263D0 (en) | 1996-12-18 | 1997-02-05 | Innovata Biomed Ltd | Powder inhaler |
| JP3530004B2 (ja) | 1998-02-06 | 2004-05-24 | 株式会社日立ユニシアオートモティブ | 吸入式投薬器 |
| JP2000217917A (ja) * | 1999-01-27 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| JP2000217919A (ja) * | 1999-01-28 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| CN2391625Y (zh) | 1999-11-07 | 2000-08-16 | 范崇盛 | 新型多用途雾化吸入器 |
| GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
| PE20020066A1 (es) * | 2000-06-23 | 2002-02-23 | Norton Healthcare Ltd | Deposito de dosis medidas previamente para inhalador de polvo seco accionado por la respiracion |
| DE10040528A1 (de) * | 2000-08-18 | 2002-02-28 | Pari Gmbh | Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke |
| ATE503517T2 (de) * | 2002-07-31 | 2011-04-15 | Chiesi Farma Spa | Pulverinhalator |
| DE10244795A1 (de) * | 2002-09-26 | 2004-04-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
-
2005
- 2005-04-04 CN CNB2005100386811A patent/CN100431634C/zh not_active Expired - Fee Related
-
2006
- 2006-03-13 AT AT06722039T patent/ATE539785T1/de active
- 2006-03-13 WO PCT/CN2006/000381 patent/WO2006105709A1/zh not_active Ceased
- 2006-03-13 JP JP2008503352A patent/JP5086988B2/ja not_active Expired - Fee Related
- 2006-03-13 EP EP06722039A patent/EP1872817B1/en not_active Revoked
- 2006-03-13 US US11/887,755 patent/US8978645B2/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1189223C (zh) * | 1998-08-14 | 2005-02-16 | 尼科-普夫公司 | 吸入器 |
| JP2004129915A (ja) * | 2002-10-11 | 2004-04-30 | Otsuka Pharmaceut Co Ltd | 粉末吸入器 |
| JP2004329678A (ja) * | 2003-05-09 | 2004-11-25 | Otsuka Pharmaceut Co Ltd | 粉末吸入器 |
| CN2794531Y (zh) * | 2005-04-04 | 2006-07-12 | 陈庆堂 | 干粉气溶胶化吸入器 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006105709A1 (en) | 2006-10-12 |
| JP2008534091A (ja) | 2008-08-28 |
| US20090025720A1 (en) | 2009-01-29 |
| EP1872817B1 (en) | 2012-01-04 |
| CN1666788A (zh) | 2005-09-14 |
| JP5086988B2 (ja) | 2012-11-28 |
| US8978645B2 (en) | 2015-03-17 |
| EP1872817A4 (en) | 2010-07-14 |
| ATE539785T1 (de) | 2012-01-15 |
| EP1872817A1 (en) | 2008-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: CHEN QINGTANG; APPLICANT Free format text: FORMER OWNER: CHEN QINGTANG Effective date: 20060526 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20060526 Address after: Yueqing City, Zhejiang province 325606 wengyang Town Street Industrial Zone (Huada electronics company hospital) Yueqing Hong Wah medical supplies Co. Ltd. Applicant after: Chen Qingtang Co-applicant after: Chen Xin Address before: Gulou District of Nanjing City, Jiangsu province 210036 Dong Po No. 6 Building 7 Room 301 1 Applicant before: Chen Qingtang |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20081112 Termination date: 20120404 |