JP2008528510A - 紅潮および／または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用 - Google Patents

紅潮および／または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用 Download PDF

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JP2008528510A
JP2008528510A JP2007552335A JP2007552335A JP2008528510A JP 2008528510 A JP2008528510 A JP 2008528510A JP 2007552335 A JP2007552335 A JP 2007552335A JP 2007552335 A JP2007552335 A JP 2007552335A JP 2008528510 A JP2008528510 A JP 2008528510A
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compound
formula
further embodiment
sirtuin activating
activating compound
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JP2008528510A5 (enExample
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デイビッド シンクレア，
マイケル ミルバーン，
ロバート エス． ランガー，
クリストフ エイチ． ウェストファール，
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サートリス ファーマシューティカルズ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61K38/22—Hormones
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  • Diabetes (AREA)
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2007552335A 2005-01-20 2006-01-20 紅潮および／または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用 Withdrawn JP2008528510A (ja)

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Application Number Priority Date Filing Date Title
US64591605P 2005-01-20 2005-01-20
US64596205P 2005-01-21 2005-01-21
PCT/US2006/002267 WO2006079021A2 (en) 2005-01-20 2006-01-20 Use of sirtuin-activating compounds for treating flushing and drug induced weight gain

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JP2008528510A true JP2008528510A (ja) 2008-07-31
JP2008528510A5 JP2008528510A5 (enExample) 2009-01-29

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US (1) US20060276416A1 (enExample)
EP (1) EP1841415A2 (enExample)
JP (1) JP2008528510A (enExample)
AU (1) AU2006206274A1 (enExample)
CA (1) CA2595486A1 (enExample)
WO (1) WO2006079021A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
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JP2012236793A (ja) * 2011-05-11 2012-12-06 Kikkoman Corp Ａｍｐｋ活性化剤
WO2013100111A1 (ja) * 2011-12-27 2013-07-04 油田 正樹 サーチュイン活性化剤
JP2016516040A (ja) * 2013-03-15 2016-06-02 ニューサート サイエンシーズ， インコーポレイテッド 脂質レベルを低下させるロイシンおよびニコチン酸

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