JP2008525445A5 - - Google Patents
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- JP2008525445A5 JP2008525445A5 JP2007548226A JP2007548226A JP2008525445A5 JP 2008525445 A5 JP2008525445 A5 JP 2008525445A5 JP 2007548226 A JP2007548226 A JP 2007548226A JP 2007548226 A JP2007548226 A JP 2007548226A JP 2008525445 A5 JP2008525445 A5 JP 2008525445A5
- Authority
- JP
- Japan
- Prior art keywords
- iron
- acid
- composition
- iron absorption
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 72
- 229910052742 iron Inorganic materials 0.000 claims 36
- 239000000203 mixture Substances 0.000 claims 22
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 16
- 238000010521 absorption reaction Methods 0.000 claims 15
- 229940124532 absorption promoter Drugs 0.000 claims 13
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 12
- 239000003623 enhancer Substances 0.000 claims 11
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 5
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 4
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 4
- 229930003268 Vitamin C Natural products 0.000 claims 4
- 235000011054 acetic acid Nutrition 0.000 claims 4
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims 4
- 229960005070 ascorbic acid Drugs 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 150000002506 iron compounds Chemical class 0.000 claims 4
- 235000019154 vitamin C Nutrition 0.000 claims 4
- 239000011718 vitamin C Substances 0.000 claims 4
- 150000002505 iron Chemical class 0.000 claims 3
- 239000002994 raw material Substances 0.000 claims 3
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 2
- QXKAIJAYHKCRRA-UHFFFAOYSA-N D-lyxonic acid Natural products OCC(O)C(O)C(O)C(O)=O QXKAIJAYHKCRRA-UHFFFAOYSA-N 0.000 claims 2
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 2
- 239000002211 L-ascorbic acid Substances 0.000 claims 2
- 235000000069 L-ascorbic acid Nutrition 0.000 claims 2
- QXKAIJAYHKCRRA-PZGQECOJSA-N L-lyxonic acid Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)C(O)=O QXKAIJAYHKCRRA-PZGQECOJSA-N 0.000 claims 2
- JPIJQSOTBSSVTP-STHAYSLISA-N L-threonic acid Chemical compound OC[C@H](O)[C@@H](O)C(O)=O JPIJQSOTBSSVTP-STHAYSLISA-N 0.000 claims 2
- QXKAIJAYHKCRRA-NUNKFHFFSA-N L-xylonic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)C(O)=O QXKAIJAYHKCRRA-NUNKFHFFSA-N 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims 2
- 239000004260 Potassium ascorbate Substances 0.000 claims 2
- 235000010323 ascorbic acid Nutrition 0.000 claims 2
- 239000011668 ascorbic acid Substances 0.000 claims 2
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical group O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims 2
- 235000010376 calcium ascorbate Nutrition 0.000 claims 2
- 229940047036 calcium ascorbate Drugs 0.000 claims 2
- 239000011692 calcium ascorbate Substances 0.000 claims 2
- BLORRZQTHNGFTI-ZZMNMWMASA-L calcium-L-ascorbate Chemical compound [Ca+2].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] BLORRZQTHNGFTI-ZZMNMWMASA-L 0.000 claims 2
- 235000015165 citric acid Nutrition 0.000 claims 2
- 150000001860 citric acid derivatives Chemical class 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229930195712 glutamate Natural products 0.000 claims 2
- 235000013922 glutamic acid Nutrition 0.000 claims 2
- 239000004220 glutamic acid Substances 0.000 claims 2
- 150000002306 glutamic acid derivatives Chemical class 0.000 claims 2
- 230000000968 intestinal effect Effects 0.000 claims 2
- 150000004698 iron complex Chemical class 0.000 claims 2
- 229940056902 l- threonic acid Drugs 0.000 claims 2
- 239000004310 lactic acid Substances 0.000 claims 2
- 235000014655 lactic acid Nutrition 0.000 claims 2
- 229940074358 magnesium ascorbate Drugs 0.000 claims 2
- AIOKQVJVNPDJKA-ZZMNMWMASA-L magnesium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2h-furan-3-olate Chemical compound [Mg+2].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] AIOKQVJVNPDJKA-ZZMNMWMASA-L 0.000 claims 2
- 229940049920 malate Drugs 0.000 claims 2
- 239000001630 malic acid Substances 0.000 claims 2
- 235000011090 malic acid Nutrition 0.000 claims 2
- 150000004701 malic acid derivatives Chemical class 0.000 claims 2
- 150000007524 organic acids Chemical class 0.000 claims 2
- 235000019275 potassium ascorbate Nutrition 0.000 claims 2
- 229940017794 potassium ascorbate Drugs 0.000 claims 2
- CONVKSGEGAVTMB-RXSVEWSESA-M potassium-L-ascorbate Chemical compound [K+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] CONVKSGEGAVTMB-RXSVEWSESA-M 0.000 claims 2
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims 2
- 235000010378 sodium ascorbate Nutrition 0.000 claims 2
- 229960005055 sodium ascorbate Drugs 0.000 claims 2
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 2
- 239000001384 succinic acid Substances 0.000 claims 2
- 150000003443 succinic acid derivatives Chemical class 0.000 claims 2
- 230000009885 systemic effect Effects 0.000 claims 2
- 229940056904 zinc ascorbate Drugs 0.000 claims 2
- WWRJFSIRMWUMAE-ZZMNMWMASA-L zinc;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2h-furan-4-olate Chemical compound [Zn+2].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] WWRJFSIRMWUMAE-ZZMNMWMASA-L 0.000 claims 2
- OTTPVANZKZRSBY-UHFFFAOYSA-N 2-aminoacetic acid;iron Chemical compound [Fe].NCC(O)=O.NCC(O)=O OTTPVANZKZRSBY-UHFFFAOYSA-N 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims 1
- -1 iron amino acid Chemical class 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/020,801 US20060134227A1 (en) | 2004-12-22 | 2004-12-22 | Compositions including iron |
| PCT/US2005/041139 WO2006068729A2 (en) | 2004-12-22 | 2005-11-09 | Methods and compositions for enhancing iron absorption |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008525445A JP2008525445A (ja) | 2008-07-17 |
| JP2008525445A5 true JP2008525445A5 (https=) | 2008-12-25 |
Family
ID=36596132
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007548207A Pending JP2008525442A (ja) | 2004-12-22 | 2005-10-27 | 鉄を含む組成物 |
| JP2007548226A Pending JP2008525445A (ja) | 2004-12-22 | 2005-11-09 | 鉄吸収増進のための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007548207A Pending JP2008525442A (ja) | 2004-12-22 | 2005-10-27 | 鉄を含む組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US20060134227A1 (https=) |
| EP (2) | EP1827418A4 (https=) |
| JP (2) | JP2008525442A (https=) |
| CN (1) | CN101102762A (https=) |
| AR (1) | AR052837A1 (https=) |
| AU (1) | AU2005319679A1 (https=) |
| BR (1) | BRPI0519265A2 (https=) |
| CA (1) | CA2591996A1 (https=) |
| MX (1) | MX2007008021A (https=) |
| PE (1) | PE20061122A1 (https=) |
| WO (2) | WO2006068697A2 (https=) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| WO2007035760A1 (en) * | 2005-09-20 | 2007-03-29 | Board Of Regents, The University Of Texas System | Enhanced solubility of preformed calcium citrate by adding citric acid |
| RU2423988C2 (ru) * | 2005-10-11 | 2011-07-20 | Байер Конзюмер Кер АГ | Смесь солей железа и меди, маскирующая металлический вкус |
| EP1790356A1 (de) * | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
| EP1973549B1 (en) | 2006-01-06 | 2016-07-20 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron |
| ES2395862T3 (es) * | 2006-09-28 | 2013-02-15 | Bayer Consumer Care Ag | Mezcla de sales de hierro y de cobre para enmascarar el sabor metálico |
| US8142803B2 (en) | 2007-03-22 | 2012-03-27 | Magceutics, Inc. | Magnesium compositions and uses thereof for neurological disorders |
| MX2009009939A (es) * | 2007-03-22 | 2010-09-24 | Magceutics Inc | Composiciones de magnesio y usos de la misma. |
| US7816404B2 (en) * | 2007-07-20 | 2010-10-19 | Rockwell Medical Technologies, Inc. | Methods for the preparation and use of ferric pyrophosphate citrate chelate compositions |
| US20090047362A1 (en) * | 2007-08-13 | 2009-02-19 | Keith Edward Forrester | Method for in-vitro stabilization of heavy metals |
| US8466187B2 (en) | 2007-09-18 | 2013-06-18 | Thermolife International, Llc | Amino acid compositions |
| US9125844B1 (en) | 2007-09-25 | 2015-09-08 | Argent Development Group, Llc | Nutritional supplements for women desiring to become pregnant, and pregnant and nursing women |
| US7964189B1 (en) | 2007-09-25 | 2011-06-21 | Argent Development Group, Llc | Nutritional supplements for women desiring to become pregnant, and pregnant and nursing women |
| ITMI20071979A1 (it) * | 2007-10-12 | 2009-04-13 | Massimo Baldacci | Formulazioni farmaceutiche contenenti ferro bisglicinato chelato |
| US20090124572A1 (en) * | 2007-11-09 | 2009-05-14 | Deanna Jean Nelson | Iron-containing nutritional supplement |
| US8535660B1 (en) | 2008-05-27 | 2013-09-17 | Argent Development Group, Llc | Nutritional supplements for pregnant women |
| US8535659B1 (en) | 2008-05-27 | 2013-09-17 | Argent Development Group, Llc | Nutritional supplements for pregnant women |
| WO2009158032A1 (en) * | 2008-06-25 | 2009-12-30 | Fe2, Inc. | Patches and methods for the transdermal delivery of a therapeutically effective amount of iron |
| WO2010036977A2 (en) * | 2008-09-25 | 2010-04-01 | New England Medical Center Hospitals, Inc. | Combination therapies with topiramate for seizures, restless legs syndrome, and other neurological conditions |
| AU2010209328B2 (en) * | 2009-01-30 | 2015-07-02 | Ecolab Inc. | Development of an aluminum hydroxycarboxylate builder |
| US8202830B2 (en) | 2009-01-30 | 2012-06-19 | Ecolab Usa Inc. | Development of an aluminum hydroxydicarboxylate builder |
| US8821945B2 (en) | 2009-04-25 | 2014-09-02 | Fe3 Medical, Inc. | Method for transdermal iontophoretic delivery of chelated agents |
| WO2010136839A1 (en) * | 2009-05-29 | 2010-12-02 | Carlo Ghisalberti | Use of deferoxamine and related compounds in targeted delivery forms to treat an inflammatory bowel disease |
| US8178709B2 (en) * | 2009-07-21 | 2012-05-15 | Biolink Life Sciences, Inc. | Iron preparation suitable for pharmaceutical formulation and process for the preparation thereof |
| CN108938585A (zh) | 2009-07-21 | 2018-12-07 | 凯克斯生物制药公司 | 柠檬酸铁剂型 |
| US8536106B2 (en) | 2010-04-14 | 2013-09-17 | Ecolab Usa Inc. | Ferric hydroxycarboxylate as a builder |
| JP5357102B2 (ja) * | 2010-04-27 | 2013-12-04 | 日本炉機工業株式会社 | 石化遺骨灰の製造方法 |
| EP2420243A1 (en) | 2010-08-18 | 2012-02-22 | Inovativo Biomedicinas Tehnologiju Instituts, SIA | Compositions obtainable from bred beetroot juice to promote iron absorption and blood forming |
| IT1402142B1 (it) * | 2010-09-24 | 2013-08-28 | Just Pharma S R L | Formulazione integrativa finalizzata al controllo delle alterazioni multifattoriali ricorrenti nell'anemia da carenza di ferro e per colmare eventuali carenze o aumentati fabbisogni nutrizionali in alcune condizioni fisiopatologiche. |
| EP2497380A1 (en) * | 2011-03-10 | 2012-09-12 | DSM IP Assets B.V. | Process for iron supplementation of beverages |
| WO2012163938A1 (de) | 2011-05-31 | 2012-12-06 | Vifor (International) Ag | Fe(iii)-2,4-dioxo-1-carbonyl-komplexverbindungen zur behandlung und prophylaxe von eisenmangelerscheinungen und eisenmangelanämien |
| MX380927B (es) * | 2011-09-22 | 2025-03-12 | Amip | Promotor de absorcion gi superior amortiguado. |
| SG11201408521WA (en) * | 2012-06-21 | 2015-01-29 | Keryx Biopharmaceuticals Inc | Use of ferric citrate in the treatment of chronic kidney disease patients |
| CN104717968A (zh) | 2012-09-11 | 2015-06-17 | 达科他星都有限公司 | 含铁的营养补充剂 |
| CN102961338B (zh) * | 2012-12-07 | 2015-03-18 | 青岛黄海制药有限责任公司 | 一种多糖铁缓释微丸制剂及其制备方法 |
| MX377119B (es) * | 2013-06-06 | 2025-03-07 | Amip Llc | Un sistema de dosis no alimenticia suministrable oralmente que comprende hierro y un agente. |
| CN105517454B (zh) * | 2013-08-28 | 2018-07-03 | 帝斯曼知识产权资产管理有限公司 | 肉汤浓缩物的铁补充 |
| KR102339148B1 (ko) * | 2013-08-28 | 2021-12-15 | 디에스엠 아이피 어셋츠 비.브이. | 부용 농축물의 철 보충 |
| CN104955452B (zh) * | 2013-09-05 | 2017-06-09 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物在制备抗癌症的药物中的用途 |
| TWI483721B (zh) | 2013-09-05 | 2015-05-11 | Profeat Biotechnology Co Ltd | The use of a composition containing a ferrous amino acid chelate for the manufacture of anti-cancer medicaments |
| US9492421B1 (en) | 2013-11-14 | 2016-11-15 | Argent Development Group, Llc | Nutritional supplements for treatment of iron deficiency anemia |
| US9629846B1 (en) | 2013-11-14 | 2017-04-25 | Argent Development Group, Llc | Nutritional supplements for women desiring to become pregnant, and pregnant and nursing women |
| CN104644557B (zh) * | 2013-11-22 | 2017-10-31 | 上海宣泰医药科技有限公司 | 卟啉铁固体分散体及其制备方法 |
| JP2014051535A (ja) * | 2013-12-19 | 2014-03-20 | Fujifilm Corp | 鉄、カルシウム、又はマグネシウムの吸収を促進する方法 |
| CN104887696B (zh) * | 2014-03-04 | 2018-06-29 | 天津怀仁制药有限公司 | 右旋糖酐铁和维生素c的复方制剂 |
| CN106537144A (zh) * | 2014-08-05 | 2017-03-22 | 富士胶片株式会社 | 有核红血球的分选方法 |
| ES2966909T3 (es) | 2014-08-13 | 2024-04-25 | Akeso Biomedical Inc | Compuestos y composiciones antimicrobianos, y usos de los mismos |
| GB201416293D0 (en) * | 2014-09-15 | 2014-10-29 | Solvotrin Therapeutics Ltd | Methods and preparations |
| JP5757493B1 (ja) * | 2014-09-24 | 2015-07-29 | 富田製薬株式会社 | 経口型鉄分補給用固形組成物及びその製造方法 |
| EP3216782B1 (en) * | 2014-11-07 | 2021-06-02 | NPA - Núcleo De Pesquisas Aplicadas LTDA. | Iron amino acid compounds, method for preparing iron amino acid compounds, compositions containing iron amino acid compounds, and uses thereof |
| JP6440843B2 (ja) | 2014-12-01 | 2018-12-19 | 普惠徳生技股▲ふん▼有限公司 | 脂肪代謝の調節に供する医薬品の製造のための第一鉄アミノ酸キレートを含む組成物の使用 |
| CN104474004A (zh) * | 2014-12-09 | 2015-04-01 | 重庆综艺营养科技有限责任公司 | 改善贫血的赖氨酸螯合铁生血素 |
| US20170360075A1 (en) * | 2014-12-11 | 2017-12-21 | The Penn State Research Foundation | Medical food for the treatment of malaria and/or iron deficiency |
| US10653658B2 (en) | 2015-08-11 | 2020-05-19 | Akeso Biomedical, Inc. | Biofilm inhibiting compositions enhancing weight gain in livestock |
| US10555531B2 (en) | 2015-08-11 | 2020-02-11 | Akeso Biomedical, Inc. | Biofilm inhibiting compositions enhancing weight gain in livestock |
| CN105476953B (zh) * | 2015-09-01 | 2018-10-30 | 张伟 | 一种用于补铁的液体制剂及其制备方法 |
| JP7055738B2 (ja) * | 2015-09-04 | 2022-04-18 | ロックウェル メディカル，インコーポレイテッド | 固体の可溶性ピロリン酸第二鉄製剤、キット、およびそれを使用する方法 |
| JP6919117B2 (ja) * | 2015-12-15 | 2021-08-18 | 三菱ケミカル株式会社 | 鉄化合物含有組成物の粒子、鉄化合物の変色抑制方法、並びに鉄化合物及びビタミンｃ含有組成物 |
| EP3199167A1 (de) | 2016-01-28 | 2017-08-02 | G.L. Pharma GmbH | Arzneimittel zur behandlung von eisenmangelzuständen mit folsäuredefizit |
| CA3017556C (en) * | 2016-03-15 | 2023-12-05 | Solvotrin Therapeutics Ltd | Compositions and methods for increasing iron intake in a mammal |
| RU2720512C1 (ru) * | 2016-05-20 | 2020-04-30 | Общество С Ограниченной Ответственностью "Вик - Здоровье Животных" | Готовая к применению инъекционная композиция для профилактики и лечения железодефицитной анемии |
| EP3466434A4 (en) * | 2016-05-26 | 2020-01-22 | Profeat Biotechnology Co. Ltd. | USE OF A COMPOSITION WITH FERROUS AMINO ACID CHELATE FOR PRODUCING A MEDICINAL PRODUCT FOR REDUCING LACTIC ACID |
| CN106265731B (zh) * | 2016-09-30 | 2019-07-19 | 广西科技大学 | 硫酸亚铁骨架型缓释滴丸的制备方法 |
| WO2018148922A1 (zh) * | 2017-02-17 | 2018-08-23 | 普惠德生技股份有限公司 | 含有亚铁氨基酸螯合物的组合物用于制造治疗肝功能异常的医药品的用途 |
| HUE070809T2 (hu) * | 2017-09-11 | 2025-07-28 | Pharmacosmos Holding As | Vaskomplex vegyületek gyógyászati alkalmazásra |
| CN108635370A (zh) * | 2018-07-13 | 2018-10-12 | 山东达因海洋生物制药股份有限公司 | 一种含有右旋糖酐铁的组合物制剂及其制备方法 |
| CN110464011A (zh) * | 2018-08-07 | 2019-11-19 | 美安康质量检测技术（上海）有限公司 | 一种补血营养粉及其制备方法 |
| EP3860621A4 (en) * | 2018-10-05 | 2022-07-06 | Ampersand Biopharmaceuticals, Inc. | IRON FORMULATIONS FOR TOPICAL ADMINISTRATION AND METHODS OF TREATMENT OF IRON DEFICIENCY |
| US20210393678A1 (en) * | 2018-10-31 | 2021-12-23 | My-Or Diagnostics Ltd. | Personalized food products for ensuring adequate iron intake |
| CN113260358A (zh) * | 2018-12-20 | 2021-08-13 | 普惠德生技股份有限公司 | 含有亚铁胺基酸螯合物粒子的组合物用于制备治疗或减缓神经受损相关疾病的医药品的用途 |
| CA3087911A1 (en) | 2018-12-20 | 2020-06-25 | Profeat Biotechnology Co., Ltd. | Composition comprising ferrous amino acid particles and use thereof in manufacture of medicament for treating or ameliorating pancreas-related disase |
| CN112168843A (zh) * | 2019-07-05 | 2021-01-05 | 普惠德生技股份有限公司 | 经烧结的纳米粒子及其抗病毒的用途 |
| MX2023009015A (es) | 2021-02-11 | 2023-08-08 | Thermolife Int Llc | Un metodo para administrar gas de oxido nitrico. |
| US12059399B2 (en) * | 2021-06-30 | 2024-08-13 | Getwing Biotechnology Medical Co., Ltd | Methods for alleviating kidney disease and fibrosis of organ |
| WO2023272693A1 (zh) * | 2021-07-01 | 2023-01-05 | 思瑰瑞保健食品有限公司 | 一种维生素c加硫酸亚铁缓控释片及其制备方法 |
| WO2023023029A1 (en) * | 2021-08-16 | 2023-02-23 | Thermolife International, Llc | Iron supplement compositions and methods of use thereof |
| CN114028423B (zh) * | 2021-12-13 | 2023-05-23 | 广东粤港澳大湾区国家纳米科技创新研究院 | 修饰的纳米氧化铁在制备预防和/或治疗炎性肠病的药物中的应用 |
| CN114288320A (zh) * | 2021-12-29 | 2022-04-08 | 珠海天翼医药技术开发有限公司 | 一种猪用口服补铁剂及其制备方法 |
| CN114767710B (zh) * | 2022-04-12 | 2023-07-07 | 中山大学 | 甘氨酸亚铁在治疗类风湿关节炎中的应用 |
| CN116636620B (zh) * | 2023-05-25 | 2025-02-14 | 南昌大学 | 一种乌鸡蛋清肽组合物及其应用 |
| CA3280511A1 (en) | 2024-07-18 | 2026-03-01 | Malian Biologicals Gmbh | Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases and iron supplementation in neurodevelopmental or psychiatric disorder |
| WO2026042887A1 (ja) * | 2024-08-23 | 2026-02-26 | 株式会社海水化学研究所 | 鉄分補給剤 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB933108A (en) * | 1960-02-03 | 1963-08-08 | Haessle Ab | Improvements in or relating to pharmaceutical iron preparations |
| GB1266356A (https=) * | 1968-08-08 | 1972-03-08 | ||
| GB1292820A (en) * | 1969-08-28 | 1972-10-11 | Aspro Nicholas Ltd | Haematinic preparations |
| GB1338071A (en) * | 1970-11-25 | 1973-11-21 | Laso Martinez V | Pharmaceutical iron preparations |
| US3773929A (en) * | 1972-11-02 | 1973-11-20 | Diagnostic Data Inc | Pharmaceutical compositions comprising orgotein and their use |
| US4362710A (en) * | 1980-07-04 | 1982-12-07 | Nissan Gosei Kogyo Co., Ltd. | Feeds for baby pigs, process for preparing the same and method of breeding baby pigs |
| US4599152A (en) * | 1985-05-24 | 1986-07-08 | Albion Laboratories | Pure amino acid chelates |
| US4863898A (en) * | 1986-02-06 | 1989-09-05 | Albion International, Inc. | Amino acid chelated compositions for delivery to specific biological tissue sites |
| US4752479A (en) * | 1986-05-27 | 1988-06-21 | Ciba-Geigy Corporaton | Multi vitamin and mineral dietary supplement with controlled release bioavailable iron |
| US4830716B1 (en) * | 1986-07-03 | 1999-12-07 | Albion Int | Preparation of pharmaceutical grade amino acid chelates |
| US5070085A (en) * | 1987-04-10 | 1991-12-03 | Oxycal Laboratories, Inc. | Compositions and methods for administering therapeutically active compounds |
| US4822816A (en) * | 1987-04-10 | 1989-04-18 | Oxycal Laboratories, Inc. | Compositions and methods for administering vitamin C |
| FR2642420B1 (fr) * | 1989-01-27 | 1991-09-06 | Valpan Sa Labo Pharma | Nouvelle forme galenique a liberation programmee contenant une association de sels ferreux, d'acide succinique et d'acide ascorbique |
| JPH0674206B2 (ja) * | 1989-12-28 | 1994-09-21 | 田辺製薬株式会社 | 放出制御型製剤およびその製法 |
| US6451341B1 (en) * | 1990-02-05 | 2002-09-17 | Thomas J. Slaga | Time release formulation of vitamins, minerals and other beneficial supplements |
| HU207799B (en) * | 1991-07-24 | 1993-06-28 | Beres Export Import Rt | Process for producing pharmaceutical composition for influencing the reticuloendothelial system, for treating chronic pain symptomes of degenerative locomotor disorders or tumors, and for treating mucoviscidosis |
| US5662922A (en) * | 1992-01-20 | 1997-09-02 | Christensen; Borge Holm | Iron-containing composition for the prevention of anaemia and a method for producing the composition |
| US5516925A (en) * | 1994-08-23 | 1996-05-14 | Albion International, Inc. | Amino acid chelates having improved palatability |
| JP2590449B2 (ja) * | 1995-04-21 | 1997-03-12 | 農林水産省畜産試験場長 | 新生子牛の造血機能の改善及び貧血の予防方法 |
| AU7455996A (en) * | 1995-10-27 | 1997-05-15 | Procter & Gamble Company, The | Color stable iron, zinc and vitamin fortified dry drink mixes |
| US5770226A (en) * | 1996-07-10 | 1998-06-23 | Wake Forest University | Combined pharmaceutical estrogen-androgen-progestin oral contraceptive |
| CA2230801A1 (en) * | 1998-02-27 | 1999-08-27 | Stanley H. Zlotkin | Composition comprising micro-encapsulated iron |
| US6521247B1 (en) * | 1999-08-13 | 2003-02-18 | Warner Chilcott Laboratories Ireland Limited | Dual iron containing nutritional supplement |
| US6495177B1 (en) * | 1999-08-13 | 2002-12-17 | Warner Chilcott Laboratories Ireland Limited | Orally dissolvable nutritional supplement |
| CN1396908A (zh) * | 2000-01-28 | 2003-02-12 | 宝洁公司 | 美味的精氨酸化合物及其用于心血管健康的应用 |
| US20020013331A1 (en) * | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
| US6924273B2 (en) * | 2000-10-03 | 2005-08-02 | Scott W. Pierce | Chondroprotective/restorative compositions and methods of use thereof |
| US6716814B2 (en) * | 2001-08-16 | 2004-04-06 | Albion International, Inc. | Enhancing solubility of iron amino acid chelates and iron proteinates |
| US6906038B2 (en) * | 2001-08-29 | 2005-06-14 | Abbott Laboratories | Methods for alleviating mucositis |
| US20030190355A1 (en) * | 2002-04-05 | 2003-10-09 | Hermelin Marc S. | Modified release minerals |
| US7994217B2 (en) * | 2002-05-02 | 2011-08-09 | Xanodyne Pharmaceuticals, Inc. | Prenatal multivitamin/multimineral supplement |
| WO2004005338A1 (en) * | 2002-07-08 | 2004-01-15 | Genova, Ltd. | Secreted peptides |
| US20030045473A1 (en) * | 2002-07-19 | 2003-03-06 | Sarama Robert Joseph | Compositions, kits, and methods for cardiovascular health |
| US8007846B2 (en) * | 2006-01-18 | 2011-08-30 | Albion International, Inc. | Mixed amino acid/mineral compounds having improved solubility |
-
2004
- 2004-12-22 US US11/020,801 patent/US20060134227A1/en not_active Abandoned
-
2005
- 2005-10-27 CN CNA2005800470364A patent/CN101102762A/zh active Pending
- 2005-10-27 EP EP05813755A patent/EP1827418A4/en not_active Withdrawn
- 2005-10-27 BR BRPI0519265-0A patent/BRPI0519265A2/pt not_active IP Right Cessation
- 2005-10-27 MX MX2007008021A patent/MX2007008021A/es unknown
- 2005-10-27 CA CA002591996A patent/CA2591996A1/en not_active Abandoned
- 2005-10-27 AU AU2005319679A patent/AU2005319679A1/en not_active Abandoned
- 2005-10-27 JP JP2007548207A patent/JP2008525442A/ja active Pending
- 2005-10-27 WO PCT/US2005/038859 patent/WO2006068697A2/en not_active Ceased
- 2005-11-09 JP JP2007548226A patent/JP2008525445A/ja active Pending
- 2005-11-09 WO PCT/US2005/041139 patent/WO2006068729A2/en not_active Ceased
- 2005-11-09 EP EP05820746A patent/EP1827419A4/en not_active Withdrawn
- 2005-11-09 US US11/793,517 patent/US20090028962A1/en not_active Abandoned
- 2005-12-01 PE PE2005001394A patent/PE20061122A1/es not_active Application Discontinuation
- 2005-12-21 AR ARP050105442A patent/AR052837A1/es unknown
-
2010
- 2010-09-27 US US12/891,376 patent/US20110015150A1/en not_active Abandoned
-
2012
- 2012-07-20 US US13/554,243 patent/US20130189374A1/en not_active Abandoned
-
2015
- 2015-02-27 US US14/634,312 patent/US20160022631A1/en not_active Abandoned
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