JP2008523407A5 - - Google Patents
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- JP2008523407A5 JP2008523407A5 JP2007546215A JP2007546215A JP2008523407A5 JP 2008523407 A5 JP2008523407 A5 JP 2008523407A5 JP 2007546215 A JP2007546215 A JP 2007546215A JP 2007546215 A JP2007546215 A JP 2007546215A JP 2008523407 A5 JP2008523407 A5 JP 2008523407A5
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- JP
- Japan
- Prior art keywords
- assay method
- fluorescence intensity
- subpopulation
- patient
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000003556 assay Methods 0.000 claims 29
- 210000001616 monocyte Anatomy 0.000 claims 9
- 210000003714 granulocyte Anatomy 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 201000010099 disease Diseases 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 239000000975 dye Substances 0.000 claims 6
- 210000000265 leukocyte Anatomy 0.000 claims 6
- 210000004698 lymphocyte Anatomy 0.000 claims 6
- 239000003550 marker Substances 0.000 claims 6
- 208000036142 Viral infection Diseases 0.000 claims 5
- 210000004369 blood Anatomy 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 210000003743 erythrocyte Anatomy 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 3
- 210000000170 cell membrane Anatomy 0.000 claims 3
- 238000012544 monitoring process Methods 0.000 claims 3
- 244000045947 parasite Species 0.000 claims 3
- 230000009385 viral infection Effects 0.000 claims 3
- 230000003612 virological effect Effects 0.000 claims 3
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 claims 2
- 101000917858 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A Proteins 0.000 claims 2
- 101000917839 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-B Proteins 0.000 claims 2
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 claims 2
- 102100029185 Low affinity immunoglobulin gamma Fc region receptor III-B Human genes 0.000 claims 2
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 claims 2
- 208000030852 Parasitic disease Diseases 0.000 claims 2
- 206010042566 Superinfection Diseases 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000007850 fluorescent dye Substances 0.000 claims 2
- 230000003834 intracellular effect Effects 0.000 claims 2
- 210000000207 lymphocyte subset Anatomy 0.000 claims 2
- 230000002934 lysing effect Effects 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 238000010186 staining Methods 0.000 claims 2
- 208000030507 AIDS Diseases 0.000 claims 1
- 206010061818 Disease progression Diseases 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 238000000149 argon plasma sintering Methods 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 239000002791 cell membrane marker Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000004748 cultured cell Anatomy 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000005750 disease progression Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000000834 fixative Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000003071 parasitic effect Effects 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 201000008827 tuberculosis Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA200410087 | 2004-12-14 | ||
| PCT/IB2005/003738 WO2006067572A2 (en) | 2004-12-14 | 2005-12-12 | A method for diagnosing and monitoring cellular reservoirs of disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008523407A JP2008523407A (ja) | 2008-07-03 |
| JP2008523407A5 true JP2008523407A5 (https=) | 2008-10-30 |
Family
ID=36294448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007546215A Withdrawn JP2008523407A (ja) | 2004-12-14 | 2005-12-12 | 疾患の細胞貯蔵庫を診断しモニターする方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090258347A1 (https=) |
| EP (1) | EP1836490A2 (https=) |
| JP (1) | JP2008523407A (https=) |
| WO (1) | WO2006067572A2 (https=) |
| ZA (1) | ZA200705737B (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG174650A1 (en) * | 2010-03-31 | 2011-10-28 | Agency Science Tech & Res | A method of monitoring parasite development in blood |
| US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
| CN102154264B (zh) * | 2011-01-25 | 2012-05-30 | 天根生化科技（北京）有限公司 | 一种快速提取血液总核糖核酸的方法 |
| US10640807B2 (en) | 2011-12-29 | 2020-05-05 | S.D. Sight Diagnostics Ltd | Methods and systems for detecting a pathogen in a biological sample |
| EP2999988A4 (en) | 2013-05-23 | 2017-01-11 | S.D. Sight Diagnostics Ltd. | Method and system for imaging a cell sample |
| IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
| WO2015029032A1 (en) | 2013-08-26 | 2015-03-05 | Parasight Ltd. | Digital microscopy systems, methods and computer program products |
| JP2014132001A (ja) * | 2014-01-15 | 2014-07-17 | Univ Of Tsukuba | 細胞透過型新規蛍光色素 |
| US10482595B2 (en) | 2014-08-27 | 2019-11-19 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
| FR3030576B1 (fr) * | 2014-12-22 | 2018-03-30 | Centre National De La Recherche Scientifique (Cnrs) | Methode d'identification de cellules |
| US10488644B2 (en) | 2015-09-17 | 2019-11-26 | S.D. Sight Diagnostics Ltd. | Methods and apparatus for detecting an entity in a bodily sample |
| CA3018536A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Distinguishing between blood sample components |
| CN105759038A (zh) * | 2016-04-15 | 2016-07-13 | 肖乐义 | 一种检测生物样品中结核分枝杆菌的免疫检测方法及试剂盒 |
| WO2017195205A1 (en) | 2016-05-11 | 2017-11-16 | S.D. Sight Diagnostics Ltd | Sample carrier for optical measurements |
| EP3455626B1 (en) | 2016-05-11 | 2025-08-06 | S.D. Sight Diagnostics Ltd. | Performing optical measurements on a sample |
| CN111788471B (zh) | 2017-11-14 | 2023-12-12 | 思迪赛特诊断有限公司 | 用于光学测量的样品载体 |
| US20210389225A1 (en) * | 2018-12-01 | 2021-12-16 | Mingdao Innovation (Beijing) Medical-Tech Co., Ltd. | A flow cytometric detection method for lymphocyte in immune cells |
| AU2020370212B2 (en) | 2019-10-22 | 2025-09-25 | S.D. Sight Diagnostics Ltd | Accounting for errors in optical measurements |
| JP7677972B2 (ja) | 2019-12-12 | 2025-05-15 | エス．ディー．サイト ダイアグノスティックス リミテッド | カラー血液スミア画像の人工的な生成 |
| CN114787625B (zh) | 2019-12-12 | 2026-01-13 | 思迪赛特诊断有限公司 | 检测血液样品中的血小板 |
| BR112022011312A2 (pt) | 2019-12-12 | 2022-08-23 | S D Sight Diagnostics Ltd | Análise de um analito disposto dentro de um meio |
| CN111879684B (zh) * | 2020-06-18 | 2021-12-21 | 山东大学 | 一种基于流式细胞术的吞噬细胞功能检测方法 |
| CN111812070B (zh) * | 2020-06-30 | 2023-08-11 | 迈克医疗电子有限公司 | 核左移以及取值范围的确定方法、装置和细胞分析仪 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5385822A (en) * | 1988-05-02 | 1995-01-31 | Zynaxis, Inc. | Methods for detection and quantification of cell subsets within subpopulations of a mixed cell population |
| IE76732B1 (en) * | 1990-08-07 | 1997-11-05 | Becton Dickinson Co | One step test for absolute counts |
| EP1474772A4 (en) * | 2002-02-14 | 2005-11-09 | Immunivest Corp | METHODS AND ALGORITHMS FOR COUNTING CELLS IN A SMALL CYTOMETER |
-
2005
- 2005-12-12 ZA ZA200705737A patent/ZA200705737B/xx unknown
- 2005-12-12 WO PCT/IB2005/003738 patent/WO2006067572A2/en not_active Ceased
- 2005-12-12 JP JP2007546215A patent/JP2008523407A/ja not_active Withdrawn
- 2005-12-12 EP EP05850690A patent/EP1836490A2/en not_active Withdrawn
- 2005-12-12 US US11/721,760 patent/US20090258347A1/en not_active Abandoned
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