JP2008523376A - 生体の画像化の方法、ならびにそのための装置およびコンピュータソフトウェア - Google Patents

生体の画像化の方法、ならびにそのための装置およびコンピュータソフトウェア Download PDF

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Publication number
JP2008523376A
JP2008523376A JP2007544985A JP2007544985A JP2008523376A JP 2008523376 A JP2008523376 A JP 2008523376A JP 2007544985 A JP2007544985 A JP 2007544985A JP 2007544985 A JP2007544985 A JP 2007544985A JP 2008523376 A JP2008523376 A JP 2008523376A
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contrast
image
organisms
contrast agent
environment
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JP2007544985A
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Japanese (ja)
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JP2008523376A5 (enExample
Inventor
アディ，イレイン・ジェイ
アリニ，ニコラス・ソルヴァトーレ
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ジーイー・ヘルスケア・ユーケイ・リミテッド
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Publication of JP2008523376A publication Critical patent/JP2008523376A/ja
Publication of JP2008523376A5 publication Critical patent/JP2008523376A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/11—Region-based segmentation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10064—Fluorescence image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
JP2007544985A 2004-12-10 2005-12-09 生体の画像化の方法、ならびにそのための装置およびコンピュータソフトウェア Pending JP2008523376A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0427050.0A GB0427050D0 (en) 2004-12-10 2004-12-10 Method of,and apparatus and computer software for,imaging biological objects
PCT/GB2005/004747 WO2006061640A2 (en) 2004-12-10 2005-12-09 Method of, and apparatus and computer software for imaging biological objects

Publications (2)

Publication Number Publication Date
JP2008523376A true JP2008523376A (ja) 2008-07-03
JP2008523376A5 JP2008523376A5 (enExample) 2012-07-26

Family

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JP2007544985A Pending JP2008523376A (ja) 2004-12-10 2005-12-09 生体の画像化の方法、ならびにそのための装置およびコンピュータソフトウェア

Country Status (5)

Country Link
US (1) US7881509B2 (enExample)
EP (1) EP1831668A2 (enExample)
JP (1) JP2008523376A (enExample)
GB (1) GB0427050D0 (enExample)
WO (1) WO2006061640A2 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013157283A1 (ja) * 2012-04-18 2013-10-24 オリンパス株式会社 標的粒子の検出方法
JP2014512548A (ja) * 2011-04-28 2014-05-22 バイオ−ラッド ラボラトリーズ インコーポレーティッド マルチバンド検出を備えた蛍光走査ヘッド
JPWO2013031309A1 (ja) * 2011-08-26 2015-03-23 オリンパス株式会社 光分析を用いた単一粒子検出装置、単一粒子検出方法及び単一粒子検出用コンピュータプログラム
US9188535B2 (en) 2012-04-18 2015-11-17 Olympus Corporation Single particle detection device, single particle detection method, and computer program for single particle detection, using optical analysis
JP2020515828A (ja) * 2017-04-07 2020-05-28 ヴェリリー ライフ サイエンシズ エルエルシー 落射蛍光集光用のパターン形成光学系
JP2022513046A (ja) * 2018-11-15 2022-02-07 ユニバーシティー オブ ヒューストン システム 紫外線励起を用いた切削
JP2022058674A (ja) * 2017-07-11 2022-04-12 浜松ホトニクス株式会社 試料観察装置及び試料観察方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2528864A (en) * 2014-07-31 2016-02-10 Technion Res & Dev Foundation Spectral imaging using single-axis spectrally dispersed illumination
JP7298993B2 (ja) 2018-04-09 2023-06-27 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
EP4256289A4 (en) * 2020-12-02 2024-10-30 Agilent Technologies, Inc. UNIVERSAL MULTIPLE DETECTION SYSTEM FOR MICROPLATES WITH CONFOCAL IMAGING

Citations (3)

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JP2000509827A (ja) * 1997-02-27 2000-08-02 セロミックス インコーポレイテッド 細胞に基づくスクリーニングシステム
JP2002507762A (ja) * 1998-03-16 2002-03-12 プリーラックス・インコーポレイテッド 共焦点顕微鏡イメージングシステム
JP2002318188A (ja) * 2001-01-02 2002-10-31 Becton Dickinson & Co 液体中の粒子の体積の測定方法

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US6416959B1 (en) * 1997-02-27 2002-07-09 Kenneth Giuliano System for cell-based screening
US5958675A (en) * 1997-04-18 1999-09-28 3M Innovative Properties Company Method for detecting bacteria using bacteriophage, contrast-coloring dye and precipitable dye
CA2306795C (en) * 1997-10-20 2009-01-20 Rebecca Richards-Kortum Acetic acid as contrast agent in fluorescence spectroscopy
US20030036855A1 (en) * 1998-03-16 2003-02-20 Praelux Incorporated, A Corporation Of New Jersey Method and apparatus for screening chemical compounds
US6388788B1 (en) * 1998-03-16 2002-05-14 Praelux, Inc. Method and apparatus for screening chemical compounds
GB9920758D0 (en) 1999-09-03 1999-11-03 Nycomed Amersham Plc Improved container composition for diagnostic agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000509827A (ja) * 1997-02-27 2000-08-02 セロミックス インコーポレイテッド 細胞に基づくスクリーニングシステム
JP2002355090A (ja) * 1997-02-27 2002-12-10 Cellomics Inc 細胞に基づくスクリーニングシステム
JP2002507762A (ja) * 1998-03-16 2002-03-12 プリーラックス・インコーポレイテッド 共焦点顕微鏡イメージングシステム
JP2002318188A (ja) * 2001-01-02 2002-10-31 Becton Dickinson & Co 液体中の粒子の体積の測定方法

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014512548A (ja) * 2011-04-28 2014-05-22 バイオ−ラッド ラボラトリーズ インコーポレーティッド マルチバンド検出を備えた蛍光走査ヘッド
JPWO2013031309A1 (ja) * 2011-08-26 2015-03-23 オリンパス株式会社 光分析を用いた単一粒子検出装置、単一粒子検出方法及び単一粒子検出用コンピュータプログラム
US9488578B2 (en) 2011-08-26 2016-11-08 Olympus Corporation Single particle detection device, single particle detection method, and computer program for single particle detection, using optical analysis
CN104136915B (zh) * 2012-04-18 2016-07-13 奥林巴斯株式会社 目标粒子的检测方法
US9188535B2 (en) 2012-04-18 2015-11-17 Olympus Corporation Single particle detection device, single particle detection method, and computer program for single particle detection, using optical analysis
JPWO2013157283A1 (ja) * 2012-04-18 2015-12-21 オリンパス株式会社 標的粒子の検出方法
WO2013157283A1 (ja) * 2012-04-18 2013-10-24 オリンパス株式会社 標的粒子の検出方法
CN104136915A (zh) * 2012-04-18 2014-11-05 奥林巴斯株式会社 目标粒子的检测方法
US9575060B2 (en) 2012-04-18 2017-02-21 Olympus Corporation Method for detecting a target particle
JP2020515828A (ja) * 2017-04-07 2020-05-28 ヴェリリー ライフ サイエンシズ エルエルシー 落射蛍光集光用のパターン形成光学系
JP2022058674A (ja) * 2017-07-11 2022-04-12 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
JP7329086B2 (ja) 2017-07-11 2023-08-17 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
JP2022513046A (ja) * 2018-11-15 2022-02-07 ユニバーシティー オブ ヒューストン システム 紫外線励起を用いた切削
JP7511913B2 (ja) 2018-11-15 2024-07-08 ユニバーシティー オブ ヒューストン システム 紫外線励起を用いた切削

Also Published As

Publication number Publication date
GB0427050D0 (en) 2005-01-12
US20090232370A1 (en) 2009-09-17
US7881509B2 (en) 2011-02-01
WO2006061640A2 (en) 2006-06-15
WO2006061640A3 (en) 2007-02-22
EP1831668A2 (en) 2007-09-12

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