JP2008519848A - 抗感染性リポペプチド - Google Patents

抗感染性リポペプチド Download PDF

Info

Publication number
JP2008519848A
JP2008519848A JP2007541346A JP2007541346A JP2008519848A JP 2008519848 A JP2008519848 A JP 2008519848A JP 2007541346 A JP2007541346 A JP 2007541346A JP 2007541346 A JP2007541346 A JP 2007541346A JP 2008519848 A JP2008519848 A JP 2008519848A
Authority
JP
Japan
Prior art keywords
amino
compound
formula
resin
methylpyrrolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007541346A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008519848A5 (enExample
Inventor
ディラン・クリストファー・アレキサンダー
リチャード・エイチ・バルツ
ポール・ブライアン
マリー−フランソワーズ・コフェ−ル・ガル
ザッシャ・デケル
ヘ・シャオウェイ
ビドヤ・クルカーニ
クリストファー・リーサイザー
ビビアン・パク・ウォン・ミャオ
キーン・トルン・ヌグイェン
イアン・バリー・パー
ダニエル・リッツ
ヤンチ・チャン
Original Assignee
キュービスト ファーマシューティカルズ, インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by キュービスト ファーマシューティカルズ, インコーポレイテッド filed Critical キュービスト ファーマシューティカルズ, インコーポレイテッド
Publication of JP2008519848A publication Critical patent/JP2008519848A/ja
Publication of JP2008519848A5 publication Critical patent/JP2008519848A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2007541346A 2004-11-12 2005-11-11 抗感染性リポペプチド Withdrawn JP2008519848A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62705604P 2004-11-12 2004-11-12
US71070505P 2005-08-23 2005-08-23
PCT/US2005/040919 WO2006110185A2 (en) 2004-11-12 2005-11-11 Antiinfective lipopeptides

Publications (2)

Publication Number Publication Date
JP2008519848A true JP2008519848A (ja) 2008-06-12
JP2008519848A5 JP2008519848A5 (enExample) 2008-12-25

Family

ID=37087468

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007541346A Withdrawn JP2008519848A (ja) 2004-11-12 2005-11-11 抗感染性リポペプチド

Country Status (10)

Country Link
EP (1) EP1814588A2 (enExample)
JP (1) JP2008519848A (enExample)
KR (1) KR20070086038A (enExample)
AU (1) AU2005330517A1 (enExample)
BR (1) BRPI0517830A (enExample)
CA (1) CA2587848A1 (enExample)
IL (1) IL183109A0 (enExample)
NO (1) NO20072634L (enExample)
RU (1) RU2007121705A (enExample)
WO (1) WO2006110185A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014515371A (ja) * 2011-05-26 2014-06-30 キュービスト ファーマシューティカルズ, インコーポレイテッド Cb−183,315組成物および関連する方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ594019A (en) * 2008-12-22 2013-08-30 Cubist Pharm Inc Novel antibacterial agents for the treatment of gram positive infections
KR101723649B1 (ko) 2014-10-23 2017-04-06 서울대학교산학협력단 신규한 펩티드 화합물, 이의 생산 방법, 및 이의 용도
CN113061164B (zh) * 2021-03-29 2023-01-10 四川大学 环脂肽类化合物及其在抗类风湿关节炎药物中的应用
WO2023152229A1 (en) 2022-02-09 2023-08-17 Teitur Trophics Aps Novel peptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0017026A (pt) * 1999-12-15 2003-01-07 Cubist Pharm Inc Lipeptìdeos como agentes antibacterianos
IL150224A0 (en) * 1999-12-15 2002-12-01 Cubist Pharm Inc Lipopeptides and pharmaceutical compositions containing the same
CN1423656A (zh) * 1999-12-15 2003-06-11 卡比斯特制药公司 作为抗菌剂的脂肽
WO2003017924A2 (en) * 2001-08-06 2003-03-06 Cubist Pharmaceuticals, Inc. Lipopeptide stereoisomers, methods for preparing same, and useful intermediates
EP1421097A4 (en) * 2001-08-06 2005-07-06 Cubist Pharm Inc COMPOSITIONS AND METHODS RELATING TO THE BIOSYNTHETIC MULTIGENIC FAMILY OF DAPTOMYCIN

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014515371A (ja) * 2011-05-26 2014-06-30 キュービスト ファーマシューティカルズ, インコーポレイテッド Cb−183,315組成物および関連する方法

Also Published As

Publication number Publication date
BRPI0517830A (pt) 2008-10-21
KR20070086038A (ko) 2007-08-27
WO2006110185A3 (en) 2007-10-25
AU2005330517A1 (en) 2006-10-19
IL183109A0 (en) 2008-04-13
WO2006110185A2 (en) 2006-10-19
EP1814588A2 (en) 2007-08-08
CA2587848A1 (en) 2006-10-19
AU2005330517A2 (en) 2006-10-19
RU2007121705A (ru) 2008-12-20
NO20072634L (no) 2007-08-09

Similar Documents

Publication Publication Date Title
JP4990456B2 (ja) 抗菌剤としてのダプトマイシンアナログ
JP2011256189A (ja) ペプチド抗生物質およびその製造方法
JP2003517003A (ja) ダプトマイシンアナログおよび抗菌剤としてのそれらの使用
WO2001044274A1 (en) Lipopeptides as antibacterial agents
JP2005531486A (ja) 新規のデプシペプチドおよびこれを調製するためのプロセス
US20080051326A1 (en) Antiinfective Lipopeptides
US20090105119A1 (en) Asparagine-10-substituted nonadepsipeptides
CA2321928A1 (en) Cyclic peptide antifungal agents
US9006392B2 (en) Actagardine derivatives, and pharmaceutical use thereof
JP5653900B2 (ja) アクチノマデュラ・ナミビエンシス由来の高度に架橋したペプチド
EP1809657A1 (de) Cyclische nonapeptidamide
KR20070086038A (ko) 항감염성 리포펩티드
CN101189253A (zh) 抗感染脂肽类
KR20070083984A (ko) 리소박틴 유도체로서 사용되는 아실화 노나뎁시펩티드
JP2002535248A (ja) 環式ペプチド抗真菌剤
EP1805212B1 (de) Desoxo-nonadepsipeptide
EP1421097A2 (en) Compositions and methods relating to the daptomycin biosynthetic gene cluster
DE102004051024A1 (de) Heterocyclyl-substituierte Nonadepsipeptide
WO2001005814A1 (en) Pseudomycin n-acyl side-chain analogs
EP2872527B1 (en) Novel lantipeptide
HK1112926A (en) Daptomycin analogs as antibacterial agents

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20081105

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20081105

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20090616