JP2008519848A - 抗感染性リポペプチド - Google Patents

抗感染性リポペプチド Download PDF

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Publication number
JP2008519848A
JP2008519848A JP2007541346A JP2007541346A JP2008519848A JP 2008519848 A JP2008519848 A JP 2008519848A JP 2007541346 A JP2007541346 A JP 2007541346A JP 2007541346 A JP2007541346 A JP 2007541346A JP 2008519848 A JP2008519848 A JP 2008519848A
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JP
Japan
Prior art keywords
amino
compound
formula
resin
methylpyrrolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007541346A
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English (en)
Japanese (ja)
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JP2008519848A5 (enExample
Inventor
ディラン・クリストファー・アレキサンダー
リチャード・エイチ・バルツ
ポール・ブライアン
マリー−フランソワーズ・コフェ−ル・ガル
ザッシャ・デケル
ヘ・シャオウェイ
ビドヤ・クルカーニ
クリストファー・リーサイザー
ビビアン・パク・ウォン・ミャオ
キーン・トルン・ヌグイェン
イアン・バリー・パー
ダニエル・リッツ
ヤンチ・チャン
Original Assignee
キュービスト ファーマシューティカルズ， インコーポレイテッド
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Application filed by キュービスト ファーマシューティカルズ， インコーポレイテッド filed Critical キュービスト ファーマシューティカルズ， インコーポレイテッド
Publication of JP2008519848A publication Critical patent/JP2008519848A/ja
Publication of JP2008519848A5 publication Critical patent/JP2008519848A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2007541346A 2004-11-12 2005-11-11 抗感染性リポペプチド Withdrawn JP2008519848A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62705604P 2004-11-12 2004-11-12
US71070505P 2005-08-23 2005-08-23
PCT/US2005/040919 WO2006110185A2 (en) 2004-11-12 2005-11-11 Antiinfective lipopeptides

Publications (2)

Publication Number Publication Date
JP2008519848A true JP2008519848A (ja) 2008-06-12
JP2008519848A5 JP2008519848A5 (enExample) 2008-12-25

Family

ID=37087468

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007541346A Withdrawn JP2008519848A (ja) 2004-11-12 2005-11-11 抗感染性リポペプチド

Country Status (10)

Country Link
EP (1) EP1814588A2 (enExample)
JP (1) JP2008519848A (enExample)
KR (1) KR20070086038A (enExample)
AU (1) AU2005330517A1 (enExample)
BR (1) BRPI0517830A (enExample)
CA (1) CA2587848A1 (enExample)
IL (1) IL183109A0 (enExample)
NO (1) NO20072634L (enExample)
RU (1) RU2007121705A (enExample)
WO (1) WO2006110185A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014515371A (ja) * 2011-05-26 2014-06-30 キュービスト ファーマシューティカルズ， インコーポレイテッド Ｃｂ−１８３，３１５組成物および関連する方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2512396C2 (ru) * 2008-12-22 2014-04-10 Кьюбист Фармасьютикалз, Инк. Новые противобактериальные средства для лечения грамположительных инфекций
KR101723649B1 (ko) 2014-10-23 2017-04-06 서울대학교산학협력단 신규한 펩티드 화합물, 이의 생산 방법, 및 이의 용도
CN113061164B (zh) * 2021-03-29 2023-01-10 四川大学 环脂肽类化合物及其在抗类风湿关节炎药物中的应用
MX2024009896A (es) * 2022-02-09 2024-08-22 Teitur Trophics Aps Nuevos peptidos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020063228A (ko) * 1999-12-15 2002-08-01 큐비스트 파마슈티컬즈 인코포레이티드 항균제로서 리포펩티드
EP2298790A1 (en) * 1999-12-15 2011-03-23 Cubist Pharmaceuticals, Inc. Daptomycin analogs as antibacterial agents
EP1240182A2 (en) * 1999-12-15 2002-09-18 Cubist Pharmaceuticals, Inc. Daptomycin analogs and their use as antibacterial agents
WO2003014297A2 (en) * 2001-08-06 2003-02-20 Cubist Pharmaceuticals, Inc. Compositions and methods relating to the daptomycin biosynthetic gene cluster
EP1423137B1 (en) * 2001-08-06 2009-04-29 Cubist Pharmaceuticals, Inc. Lipopeptide stereoisomers, methods for preparing same, and useful intermediates

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014515371A (ja) * 2011-05-26 2014-06-30 キュービスト ファーマシューティカルズ， インコーポレイテッド Ｃｂ−１８３，３１５組成物および関連する方法

Also Published As

Publication number Publication date
WO2006110185A2 (en) 2006-10-19
AU2005330517A1 (en) 2006-10-19
BRPI0517830A (pt) 2008-10-21
CA2587848A1 (en) 2006-10-19
EP1814588A2 (en) 2007-08-08
RU2007121705A (ru) 2008-12-20
KR20070086038A (ko) 2007-08-27
NO20072634L (no) 2007-08-09
WO2006110185A3 (en) 2007-10-25
IL183109A0 (en) 2008-04-13
AU2005330517A2 (en) 2006-10-19

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