JP2008517940A5 - - Google Patents

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Publication number
JP2008517940A5
JP2008517940A5 JP2007538147A JP2007538147A JP2008517940A5 JP 2008517940 A5 JP2008517940 A5 JP 2008517940A5 JP 2007538147 A JP2007538147 A JP 2007538147A JP 2007538147 A JP2007538147 A JP 2007538147A JP 2008517940 A5 JP2008517940 A5 JP 2008517940A5
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JP
Japan
Prior art keywords
composition
seq
irna
sense strand
respiratory virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007538147A
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English (en)
Japanese (ja)
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JP5037349B2 (ja
JP2008517940A (ja
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Publication date
Priority claimed from US11/151,893 external-priority patent/US7592322B2/en
Application filed filed Critical
Publication of JP2008517940A publication Critical patent/JP2008517940A/ja
Publication of JP2008517940A5 publication Critical patent/JP2008517940A5/ja
Application granted granted Critical
Publication of JP5037349B2 publication Critical patent/JP5037349B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2007538147A 2004-10-22 2005-10-21 ＲＳＶ、ＰＩＶおよび他の呼吸器系ウイルスのＲＮＡｉ調節とその使用法 Expired - Fee Related JP5037349B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US62155204P 2004-10-22 2004-10-22
US60/621,552 2004-10-22
US11/151,893 2005-06-14
US11/151,893 US7592322B2 (en) 2004-10-22 2005-06-14 RNAi modulation of RSV, PIV and other respiratory viruses and uses thereof
US11/151,976 US20060089324A1 (en) 2004-10-22 2005-06-14 RNAi modulation of RSV, PIV and other respiratory viruses and uses thereof
US11/151,976 2005-06-14
PCT/US2005/038269 WO2006062596A2 (en) 2004-10-22 2005-10-21 RNAi MODULATION OF RSV, PIV AND OTHER RESPIRATORY VIRUSES AND USES THEREOF

Publications (3)

Publication Number Publication Date
JP2008517940A JP2008517940A (ja) 2008-05-29
JP2008517940A5 true JP2008517940A5 (enExample) 2008-11-27
JP5037349B2 JP5037349B2 (ja) 2012-09-26

Family

ID=36578352

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007538147A Expired - Fee Related JP5037349B2 (ja) 2004-10-22 2005-10-21 ＲＳＶ、ＰＩＶおよび他の呼吸器系ウイルスのＲＮＡｉ調節とその使用法

Country Status (12)

Country Link
US (2) US7592322B2 (enExample)
EP (1) EP1806968B1 (enExample)
JP (1) JP5037349B2 (enExample)
KR (1) KR101193825B1 (enExample)
CN (1) CN101087527B (enExample)
AU (1) AU2005314617B2 (enExample)
BR (1) BRPI0517286A (enExample)
CA (1) CA2584309A1 (enExample)
MX (1) MX2007004692A (enExample)
NO (1) NO20071953L (enExample)
RU (1) RU2494745C2 (enExample)
WO (1) WO2006062596A2 (enExample)

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US20080214437A1 (en) * 2002-09-06 2008-09-04 Mohapatra Shyam S Methods and compositions for reducing activity of the atrial natriuretic peptide receptor and for treatment of diseases
WO2006085987A2 (en) 2004-07-09 2006-08-17 University Of Iowa Research Foundation Rna interference in respiratory epitheial cells
US7790878B2 (en) * 2004-10-22 2010-09-07 Alnylam Pharmaceuticals, Inc. RNAi modulation of RSV, PIV and other respiratory viruses and uses thereof
US7507809B2 (en) * 2005-01-07 2009-03-24 Alnylam Pharmaceuticals, Inc. RNAi modulation of RSV and therapeutic uses thereof
DK2308514T3 (da) 2007-03-23 2013-09-02 To Bbb Holding B V Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren
JP2010527914A (ja) * 2007-04-26 2010-08-19 クォーク ファーマシューティカルズ インコーポレーティッド 呼吸器系への抑制性核酸分子の治療的送達
WO2009055445A2 (en) * 2007-10-22 2009-04-30 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF RESPIRATORY SYNCYTIAL VIRUS (RSV) EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
AU2008334948B2 (en) * 2007-12-13 2014-11-20 Alnylam Pharmaceuticals, Inc. Methods and compositions for prevention or treatment of RSV infection
WO2010011895A1 (en) * 2008-07-25 2010-01-28 Alnylam Pharmaceuticals, Inc. Enhancement of sirna silencing activity using universal bases or mismatches in the sense strand
EP2350277A1 (en) * 2008-10-23 2011-08-03 Alnylam Pharmaceuticals, Inc. Methods and compositions for prevention or treatment of rsv infection using modified duplex rna molecules
JP2013521771A (ja) * 2010-03-08 2013-06-13 ノバルティス アーゲー 細胞内病原体について試験する方法
EP2681315B1 (en) * 2011-03-03 2017-05-03 Quark Pharmaceuticals, Inc. Oligonucleotide modulators of the toll-like receptor pathway
US10184942B2 (en) 2011-03-17 2019-01-22 University Of South Florida Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer
JP6072766B2 (ja) * 2011-04-08 2017-02-01 バイオ−ラッド ラボラトリーズ インコーポレーティッド 非特異的活性が低下したｐｃｒ反応混合物
US11163898B2 (en) * 2013-09-11 2021-11-02 Mimecast Services Ltd. Sharing artifacts in permission-protected archives
WO2016037161A2 (en) 2014-09-07 2016-03-10 Selecta Biosciences, Inc. Methods and compositions for attenuating gene editing anti-viral transfer vector immune responses
AU2015320409B2 (en) 2014-09-26 2019-03-28 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Virus-based expression vectors and uses thereof
AU2018347583A1 (en) 2017-10-13 2020-05-21 Selecta Biosciences, Inc. Methods and compositions for attenuating anti-viral transfer vector IgM responses
WO2020243261A1 (en) 2019-05-28 2020-12-03 Selecta Biosciences, Inc. Methods and compositions for attenuated anti-viral transfer vector immune response
WO2021180219A1 (zh) * 2020-03-13 2021-09-16 挪贝肽医药科技(上海)有限公司 Pi4k抑制剂的抗冠状病毒效果以及应用
EP4162050A1 (en) * 2020-06-09 2023-04-12 Alnylam Pharmaceuticals, Inc. Rnai compositions and methods of use thereof for delivery by inhalation
WO2023064367A1 (en) 2021-10-12 2023-04-20 Selecta Biosciences, Inc. Methods and compositions for attenuating anti-viral transfer vector igm responses
WO2023172624A1 (en) 2022-03-09 2023-09-14 Selecta Biosciences, Inc. Immunosuppressants in combination with anti-igm agents and related dosing
EP4527927A1 (en) * 2023-09-22 2025-03-26 Medizinische Hochschule Hannover Oligonucleotide-based strategies to combat respiratory viruses

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US4501729A (en) 1982-12-13 1985-02-26 Research Corporation Aerosolized amiloride treatment of retained pulmonary secretions
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US20070238676A1 (en) * 2003-12-04 2007-10-11 Mohapatra Shyam S Polynucleotides for Reducing Respiratory Syncytial Virus Gene Expression
WO2006085987A2 (en) * 2004-07-09 2006-08-17 University Of Iowa Research Foundation Rna interference in respiratory epitheial cells
US7507809B2 (en) * 2005-01-07 2009-03-24 Alnylam Pharmaceuticals, Inc. RNAi modulation of RSV and therapeutic uses thereof

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