JP2008513523A5 - - Google Patents
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- Publication number
- JP2008513523A5 JP2008513523A5 JP2007532748A JP2007532748A JP2008513523A5 JP 2008513523 A5 JP2008513523 A5 JP 2008513523A5 JP 2007532748 A JP2007532748 A JP 2007532748A JP 2007532748 A JP2007532748 A JP 2007532748A JP 2008513523 A5 JP2008513523 A5 JP 2008513523A5
- Authority
- JP
- Japan
- Prior art keywords
- tmz
- carboxylate
- calculated
- measured
- following formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010028980 Neoplasm Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200410072056.4 | 2004-09-22 | ||
| CNA2004100720564A CN1752088A (zh) | 2004-09-22 | 2004-09-22 | 含有替莫唑胺酯的药用组合物 |
| PCT/CN2005/001477 WO2006032190A1 (en) | 2004-09-22 | 2005-09-15 | Pharmaceutical composition comprising temozolomide ester |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012209183A Division JP2013028630A (ja) | 2004-09-22 | 2012-09-24 | テモゾロマイドエステルよりなる医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008513523A JP2008513523A (ja) | 2008-05-01 |
| JP2008513523A5 true JP2008513523A5 (https=) | 2008-10-09 |
| JP5620046B2 JP5620046B2 (ja) | 2014-11-05 |
Family
ID=36089840
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007532748A Expired - Fee Related JP5620046B2 (ja) | 2004-09-22 | 2005-09-15 | テモゾロマイドエステルよりなる医薬組成物 |
| JP2012209183A Pending JP2013028630A (ja) | 2004-09-22 | 2012-09-24 | テモゾロマイドエステルよりなる医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012209183A Pending JP2013028630A (ja) | 2004-09-22 | 2012-09-24 | テモゾロマイドエステルよりなる医薬組成物 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7579336B2 (https=) |
| EP (1) | EP1798234B1 (https=) |
| JP (2) | JP5620046B2 (https=) |
| KR (1) | KR101065984B1 (https=) |
| CN (1) | CN1752088A (https=) |
| AR (1) | AR050947A1 (https=) |
| AU (1) | AU2005287799B2 (https=) |
| BR (1) | BRPI0515555A (https=) |
| CA (1) | CA2580910C (https=) |
| DK (1) | DK1798234T3 (https=) |
| ES (1) | ES2389376T3 (https=) |
| IL (1) | IL182027A (https=) |
| MX (1) | MX2007003366A (https=) |
| MY (1) | MY153713A (https=) |
| NZ (1) | NZ554609A (https=) |
| PL (1) | PL1798234T3 (https=) |
| RU (1) | RU2393160C2 (https=) |
| UA (1) | UA89795C2 (https=) |
| WO (1) | WO2006032190A1 (https=) |
| ZA (1) | ZA200702801B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1727340B (zh) * | 2004-07-29 | 2011-05-18 | 天津帝士力投资控股集团有限公司 | 一种替莫唑胺-8-羧酸酯及其组合物 |
| EP1808173A1 (en) * | 2006-01-12 | 2007-07-18 | Matthias Dormeyer | Use of CNS penetrating anticancer compounds for the treatment of protozan diseases |
| US8558511B2 (en) * | 2009-04-07 | 2013-10-15 | Battelle Memorial Institute | Method and apparatus for smart battery charging including a plurality of controllers each monitoring input variables |
| KR20140087846A (ko) * | 2012-12-31 | 2014-07-09 | 주식회사 삼양바이오팜 | 테모졸로미드를 포함하는 안정성이 개선된 약제학적 조성물 및 이의 제조방법 |
| RU2527258C1 (ru) * | 2013-02-19 | 2014-08-27 | Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" | 6-ЗАМЕЩЕННЫЕ 3-АЗОЛИЛИМИДАЗО[1,2-b][1,2,4,5]ТЕТРАЗИНЫ, ПРОЯВЛЯЮЩИЕ ПРОТИВООПУХОЛЕВУЮ АКТИВНОСТЬ |
| US10709715B2 (en) * | 2017-12-03 | 2020-07-14 | Cipla Limited | Method of treating hypertension |
| EP3833342A4 (en) * | 2018-08-09 | 2022-07-13 | The Board of Trustees of the University of Illinois | IMIDAZOTETRAZINE COMPOUNDS |
| CN114014862A (zh) * | 2021-06-28 | 2022-02-08 | 烟台大学 | 一种治疗脑胶质瘤的新化合物及其制备和应用 |
| CN116947765B (zh) * | 2022-06-23 | 2025-10-10 | 北京新源医疗有限责任公司 | 一种抗肿瘤药物前药、药物组合物及在肿瘤靶向治疗领域的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8616125D0 (en) * | 1986-07-02 | 1986-08-06 | May & Baker Ltd | Compositions of matter |
| UA29466C2 (uk) * | 1993-01-14 | 2000-11-15 | Канзер Рісерч Кампейн Технолоджі, Лтд | Фармацевтична композиція з антипухлинною активністю |
| CN1244583C (zh) * | 2002-09-29 | 2006-03-08 | 天津天士力集团有限公司 | 替莫唑胺－8－羧酸脂和－8－酰胺衍生物，它们的合成方法以及它们在制备抗癌制剂中的应用 |
| CN1742723A (zh) * | 2004-09-02 | 2006-03-08 | 天津倍方科技发展有限公司 | 含有替莫唑胺－8－羧酸酯的药物组合物以及该类化合物用于制备抗肿瘤药物的用途 |
-
2004
- 2004-09-22 CN CNA2004100720564A patent/CN1752088A/zh active Pending
-
2005
- 2005-09-15 NZ NZ554609A patent/NZ554609A/en not_active IP Right Cessation
- 2005-09-15 UA UAA200704418A patent/UA89795C2/ru unknown
- 2005-09-15 CA CA2580910A patent/CA2580910C/en not_active Expired - Fee Related
- 2005-09-15 BR BRPI0515555-0A patent/BRPI0515555A/pt not_active IP Right Cessation
- 2005-09-15 RU RU2007114948/04A patent/RU2393160C2/ru not_active IP Right Cessation
- 2005-09-15 US US11/575,849 patent/US7579336B2/en not_active Expired - Fee Related
- 2005-09-15 KR KR1020077009054A patent/KR101065984B1/ko not_active Expired - Fee Related
- 2005-09-15 PL PL05785075T patent/PL1798234T3/pl unknown
- 2005-09-15 MX MX2007003366A patent/MX2007003366A/es active IP Right Grant
- 2005-09-15 EP EP05785075A patent/EP1798234B1/en not_active Expired - Lifetime
- 2005-09-15 WO PCT/CN2005/001477 patent/WO2006032190A1/zh not_active Ceased
- 2005-09-15 JP JP2007532748A patent/JP5620046B2/ja not_active Expired - Fee Related
- 2005-09-15 DK DK05785075.2T patent/DK1798234T3/da active
- 2005-09-15 ES ES05785075T patent/ES2389376T3/es not_active Expired - Lifetime
- 2005-09-15 AU AU2005287799A patent/AU2005287799B2/en not_active Ceased
- 2005-09-21 AR ARP050103949A patent/AR050947A1/es not_active Application Discontinuation
- 2005-09-22 MY MYPI20054428A patent/MY153713A/en unknown
-
2007
- 2007-03-19 IL IL182027A patent/IL182027A/en not_active IP Right Cessation
- 2007-04-03 ZA ZA200702801A patent/ZA200702801B/xx unknown
-
2012
- 2012-09-24 JP JP2012209183A patent/JP2013028630A/ja active Pending
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