JP2008512416A5 - - Google Patents
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- Publication number
- JP2008512416A5 JP2008512416A5 JP2007530646A JP2007530646A JP2008512416A5 JP 2008512416 A5 JP2008512416 A5 JP 2008512416A5 JP 2007530646 A JP2007530646 A JP 2007530646A JP 2007530646 A JP2007530646 A JP 2007530646A JP 2008512416 A5 JP2008512416 A5 JP 2008512416A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- alkyl group
- substituted
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 claims 5
- 125000005843 halogen group Chemical group 0.000 claims 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 5
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 claims 4
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 claims 4
- 125000003118 aryl group Chemical group 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 3
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 3
- 125000000027 (C1-C10) alkoxy group Chemical group 0.000 claims 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000004414 alkyl thio group Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000001072 heteroaryl group Chemical group 0.000 claims 2
- 125000000468 ketone group Chemical group 0.000 claims 2
- 125000005010 perfluoroalkyl group Chemical group 0.000 claims 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 1
- 125000004649 C2-C8 alkynyl group Chemical group 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 125000002837 carbocyclic group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims 1
- 125000002950 monocyclic group Chemical group 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 125000004434 sulfur atom Chemical group 0.000 claims 1
- CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical compound C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004044680A DE102004044680B3 (de) | 2004-09-09 | 2004-09-09 | Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate |
| PCT/EP2005/009623 WO2006027236A1 (de) | 2004-09-09 | 2005-09-02 | Alkyliden-tetrahydronaphthalinderivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008512416A JP2008512416A (ja) | 2008-04-24 |
| JP2008512416A5 true JP2008512416A5 (enExample) | 2008-08-28 |
Family
ID=35517445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007530646A Withdrawn JP2008512416A (ja) | 2004-09-09 | 2005-09-02 | アルキリデン−テトラヒドロナフタレン誘導体、それらの製造方法および抗炎症剤としての使用 |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1786823B1 (enExample) |
| JP (1) | JP2008512416A (enExample) |
| KR (1) | KR20070050469A (enExample) |
| CN (1) | CN101065386A (enExample) |
| AR (1) | AR050733A1 (enExample) |
| AT (1) | ATE384069T1 (enExample) |
| AU (1) | AU2005281859A1 (enExample) |
| BR (1) | BRPI0515186A (enExample) |
| CA (1) | CA2577861A1 (enExample) |
| DE (2) | DE102004044680B3 (enExample) |
| EA (1) | EA200700550A1 (enExample) |
| EC (1) | ECSP077306A (enExample) |
| ES (1) | ES2301056T3 (enExample) |
| GT (1) | GT200500241A (enExample) |
| IL (1) | IL181832A0 (enExample) |
| MX (1) | MX2007002833A (enExample) |
| NO (1) | NO20071805L (enExample) |
| PA (1) | PA8644701A1 (enExample) |
| PE (1) | PE20060596A1 (enExample) |
| RS (1) | RS20070095A (enExample) |
| SV (1) | SV2006002220A (enExample) |
| TW (1) | TW200621703A (enExample) |
| UY (1) | UY29109A1 (enExample) |
| WO (1) | WO2006027236A1 (enExample) |
| ZA (1) | ZA200701399B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| SI1670458T1 (sl) | 2003-10-08 | 2007-06-30 | Bayer Schering Pharma Ag | Tetrahidronaftalenski derivati, postopek za njihovo pripravo in njihova uporaba kot antiinflamatoriki |
| US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102004063227A1 (de) * | 2004-12-22 | 2006-07-06 | Schering Ag | Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| EP1834948A1 (de) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| EP1917963A1 (en) * | 2006-10-31 | 2008-05-07 | Bayer Schering Pharma Aktiengesellschaft | Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents |
| CA2678615A1 (en) | 2007-02-16 | 2008-08-28 | Synta Pharmaceutical Corp. | Substituted fused-ring compounds for inflammation and immune-related uses |
| EP2072509A1 (en) | 2007-12-18 | 2009-06-24 | Bayer Schering Pharma Aktiengesellschaft | 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU698527B2 (en) * | 1994-12-29 | 1998-10-29 | Allergan, Inc. | Acetylenes disubstituted with a 5 or 8 substituted tetrahydronaphthyl or dihydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity |
| DE10038639A1 (de) * | 2000-07-28 | 2002-02-21 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| ES2298508T3 (es) * | 2002-03-26 | 2008-05-16 | Boehringer Ingelheim Pharmaceuticals Inc. | Mimeticos de glucocorticoides, metodos para prepararlos, composiciones farmaceuticas y sus usos. |
| DE10215316C1 (de) * | 2002-04-02 | 2003-12-18 | Schering Ag | Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer |
| SI1670458T1 (sl) * | 2003-10-08 | 2007-06-30 | Bayer Schering Pharma Ag | Tetrahidronaftalenski derivati, postopek za njihovo pripravo in njihova uporaba kot antiinflamatoriki |
-
2004
- 2004-09-09 DE DE102004044680A patent/DE102004044680B3/de not_active Expired - Fee Related
-
2005
- 2005-09-02 CA CA002577861A patent/CA2577861A1/en not_active Abandoned
- 2005-09-02 BR BRPI0515186-4A patent/BRPI0515186A/pt not_active Application Discontinuation
- 2005-09-02 MX MX2007002833A patent/MX2007002833A/es not_active Application Discontinuation
- 2005-09-02 AU AU2005281859A patent/AU2005281859A1/en not_active Abandoned
- 2005-09-02 RS RSP-2007/0095A patent/RS20070095A/sr unknown
- 2005-09-02 DE DE502005002595T patent/DE502005002595D1/de not_active Expired - Fee Related
- 2005-09-02 KR KR1020077005549A patent/KR20070050469A/ko not_active Withdrawn
- 2005-09-02 CN CNA2005800383722A patent/CN101065386A/zh active Pending
- 2005-09-02 AT AT05786302T patent/ATE384069T1/de not_active IP Right Cessation
- 2005-09-02 EP EP05786302A patent/EP1786823B1/de not_active Expired - Lifetime
- 2005-09-02 JP JP2007530646A patent/JP2008512416A/ja not_active Withdrawn
- 2005-09-02 WO PCT/EP2005/009623 patent/WO2006027236A1/de not_active Ceased
- 2005-09-02 ES ES05786302T patent/ES2301056T3/es not_active Expired - Lifetime
- 2005-09-02 GT GT200500241A patent/GT200500241A/es unknown
- 2005-09-02 EA EA200700550A patent/EA200700550A1/ru unknown
- 2005-09-06 TW TW094130577A patent/TW200621703A/zh unknown
- 2005-09-08 PE PE2005001041A patent/PE20060596A1/es not_active Application Discontinuation
- 2005-09-08 UY UY29109A patent/UY29109A1/es not_active Application Discontinuation
- 2005-09-08 SV SV2005002220A patent/SV2006002220A/es not_active Application Discontinuation
- 2005-09-08 PA PA20058644701A patent/PA8644701A1/es unknown
- 2005-09-09 AR ARP050103762A patent/AR050733A1/es unknown
-
2007
- 2007-02-16 ZA ZA200701399A patent/ZA200701399B/xx unknown
- 2007-03-08 IL IL181832A patent/IL181832A0/en unknown
- 2007-03-08 EC EC2007007306A patent/ECSP077306A/es unknown
- 2007-04-03 NO NO20071805A patent/NO20071805L/no not_active Application Discontinuation
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