RS20070095A - Alkiliden-tetrahidronaftalen derivati, postupak njihove proizvodnje i njihova upotreba kao anti-inflamatornih sredstava - Google Patents
Alkiliden-tetrahidronaftalen derivati, postupak njihove proizvodnje i njihova upotreba kao anti-inflamatornih sredstavaInfo
- Publication number
- RS20070095A RS20070095A RSP-2007/0095A RSP20070095A RS20070095A RS 20070095 A RS20070095 A RS 20070095A RS P20070095 A RSP20070095 A RS P20070095A RS 20070095 A RS20070095 A RS 20070095A
- Authority
- RS
- Serbia
- Prior art keywords
- group
- groups
- alkyl
- hydroxy
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004044680A DE102004044680B3 (de) | 2004-09-09 | 2004-09-09 | Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate |
| PCT/EP2005/009623 WO2006027236A1 (de) | 2004-09-09 | 2005-09-02 | Alkyliden-tetrahydronaphthalinderivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS20070095A true RS20070095A (sr) | 2008-11-28 |
Family
ID=35517445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RSP-2007/0095A RS20070095A (sr) | 2004-09-09 | 2005-09-02 | Alkiliden-tetrahidronaftalen derivati, postupak njihove proizvodnje i njihova upotreba kao anti-inflamatornih sredstava |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1786823B1 (enExample) |
| JP (1) | JP2008512416A (enExample) |
| KR (1) | KR20070050469A (enExample) |
| CN (1) | CN101065386A (enExample) |
| AR (1) | AR050733A1 (enExample) |
| AT (1) | ATE384069T1 (enExample) |
| AU (1) | AU2005281859A1 (enExample) |
| BR (1) | BRPI0515186A (enExample) |
| CA (1) | CA2577861A1 (enExample) |
| DE (2) | DE102004044680B3 (enExample) |
| EA (1) | EA200700550A1 (enExample) |
| EC (1) | ECSP077306A (enExample) |
| ES (1) | ES2301056T3 (enExample) |
| GT (1) | GT200500241A (enExample) |
| IL (1) | IL181832A0 (enExample) |
| MX (1) | MX2007002833A (enExample) |
| NO (1) | NO20071805L (enExample) |
| PA (1) | PA8644701A1 (enExample) |
| PE (1) | PE20060596A1 (enExample) |
| RS (1) | RS20070095A (enExample) |
| SV (1) | SV2006002220A (enExample) |
| TW (1) | TW200621703A (enExample) |
| UY (1) | UY29109A1 (enExample) |
| WO (1) | WO2006027236A1 (enExample) |
| ZA (1) | ZA200701399B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| SI1670458T1 (sl) | 2003-10-08 | 2007-06-30 | Bayer Schering Pharma Ag | Tetrahidronaftalenski derivati, postopek za njihovo pripravo in njihova uporaba kot antiinflamatoriki |
| US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102004063227A1 (de) * | 2004-12-22 | 2006-07-06 | Schering Ag | Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| EP1834948A1 (de) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| EP1917963A1 (en) * | 2006-10-31 | 2008-05-07 | Bayer Schering Pharma Aktiengesellschaft | Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents |
| CA2678615A1 (en) | 2007-02-16 | 2008-08-28 | Synta Pharmaceutical Corp. | Substituted fused-ring compounds for inflammation and immune-related uses |
| EP2072509A1 (en) | 2007-12-18 | 2009-06-24 | Bayer Schering Pharma Aktiengesellschaft | 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU698527B2 (en) * | 1994-12-29 | 1998-10-29 | Allergan, Inc. | Acetylenes disubstituted with a 5 or 8 substituted tetrahydronaphthyl or dihydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity |
| DE10038639A1 (de) * | 2000-07-28 | 2002-02-21 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| ES2298508T3 (es) * | 2002-03-26 | 2008-05-16 | Boehringer Ingelheim Pharmaceuticals Inc. | Mimeticos de glucocorticoides, metodos para prepararlos, composiciones farmaceuticas y sus usos. |
| DE10215316C1 (de) * | 2002-04-02 | 2003-12-18 | Schering Ag | Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer |
| SI1670458T1 (sl) * | 2003-10-08 | 2007-06-30 | Bayer Schering Pharma Ag | Tetrahidronaftalenski derivati, postopek za njihovo pripravo in njihova uporaba kot antiinflamatoriki |
-
2004
- 2004-09-09 DE DE102004044680A patent/DE102004044680B3/de not_active Expired - Fee Related
-
2005
- 2005-09-02 CA CA002577861A patent/CA2577861A1/en not_active Abandoned
- 2005-09-02 BR BRPI0515186-4A patent/BRPI0515186A/pt not_active Application Discontinuation
- 2005-09-02 MX MX2007002833A patent/MX2007002833A/es not_active Application Discontinuation
- 2005-09-02 AU AU2005281859A patent/AU2005281859A1/en not_active Abandoned
- 2005-09-02 RS RSP-2007/0095A patent/RS20070095A/sr unknown
- 2005-09-02 DE DE502005002595T patent/DE502005002595D1/de not_active Expired - Fee Related
- 2005-09-02 KR KR1020077005549A patent/KR20070050469A/ko not_active Withdrawn
- 2005-09-02 CN CNA2005800383722A patent/CN101065386A/zh active Pending
- 2005-09-02 AT AT05786302T patent/ATE384069T1/de not_active IP Right Cessation
- 2005-09-02 EP EP05786302A patent/EP1786823B1/de not_active Expired - Lifetime
- 2005-09-02 JP JP2007530646A patent/JP2008512416A/ja not_active Withdrawn
- 2005-09-02 WO PCT/EP2005/009623 patent/WO2006027236A1/de not_active Ceased
- 2005-09-02 ES ES05786302T patent/ES2301056T3/es not_active Expired - Lifetime
- 2005-09-02 GT GT200500241A patent/GT200500241A/es unknown
- 2005-09-02 EA EA200700550A patent/EA200700550A1/ru unknown
- 2005-09-06 TW TW094130577A patent/TW200621703A/zh unknown
- 2005-09-08 PE PE2005001041A patent/PE20060596A1/es not_active Application Discontinuation
- 2005-09-08 UY UY29109A patent/UY29109A1/es not_active Application Discontinuation
- 2005-09-08 SV SV2005002220A patent/SV2006002220A/es not_active Application Discontinuation
- 2005-09-08 PA PA20058644701A patent/PA8644701A1/es unknown
- 2005-09-09 AR ARP050103762A patent/AR050733A1/es unknown
-
2007
- 2007-02-16 ZA ZA200701399A patent/ZA200701399B/xx unknown
- 2007-03-08 IL IL181832A patent/IL181832A0/en unknown
- 2007-03-08 EC EC2007007306A patent/ECSP077306A/es unknown
- 2007-04-03 NO NO20071805A patent/NO20071805L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2577861A1 (en) | 2006-03-16 |
| WO2006027236A1 (de) | 2006-03-16 |
| PA8644701A1 (es) | 2006-07-03 |
| IL181832A0 (en) | 2007-07-04 |
| UY29109A1 (es) | 2006-03-31 |
| BRPI0515186A (pt) | 2008-07-22 |
| ECSP077306A (es) | 2007-04-26 |
| CN101065386A (zh) | 2007-10-31 |
| ATE384069T1 (de) | 2008-02-15 |
| KR20070050469A (ko) | 2007-05-15 |
| JP2008512416A (ja) | 2008-04-24 |
| DE502005002595D1 (de) | 2008-03-06 |
| NO20071805L (no) | 2007-06-07 |
| EP1786823B1 (de) | 2008-01-16 |
| AR050733A1 (es) | 2006-11-15 |
| SV2006002220A (es) | 2006-03-15 |
| AU2005281859A1 (en) | 2006-03-16 |
| PE20060596A1 (es) | 2006-07-26 |
| EA200700550A1 (ru) | 2007-10-26 |
| DE102004044680B3 (de) | 2006-06-08 |
| TW200621703A (en) | 2006-07-01 |
| ES2301056T3 (es) | 2008-06-16 |
| ZA200701399B (en) | 2008-09-25 |
| MX2007002833A (es) | 2007-07-09 |
| GT200500241A (es) | 2006-08-17 |
| EP1786823A1 (de) | 2007-05-23 |
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