IL181832A0 - Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agents - Google Patents
Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agentsInfo
- Publication number
- IL181832A0 IL181832A0 IL181832A IL18183207A IL181832A0 IL 181832 A0 IL181832 A0 IL 181832A0 IL 181832 A IL181832 A IL 181832A IL 18183207 A IL18183207 A IL 18183207A IL 181832 A0 IL181832 A0 IL 181832A0
- Authority
- IL
- Israel
- Prior art keywords
- alkylidene
- production
- inflammatory agents
- tetrahydronaphthalene derivatives
- tetrahydronaphthalene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004044680A DE102004044680B3 (en) | 2004-09-09 | 2004-09-09 | Alkylidene tetrahydronaphthalene derivatives, process for their preparation and their use as anti-inflammatory agents and pharmaceutical compositions containing them |
| PCT/EP2005/009623 WO2006027236A1 (en) | 2004-09-09 | 2005-09-02 | Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL181832A0 true IL181832A0 (en) | 2007-07-04 |
Family
ID=35517445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL181832A IL181832A0 (en) | 2004-09-09 | 2007-03-08 | Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agents |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1786823B1 (en) |
| JP (1) | JP2008512416A (en) |
| KR (1) | KR20070050469A (en) |
| CN (1) | CN101065386A (en) |
| AR (1) | AR050733A1 (en) |
| AT (1) | ATE384069T1 (en) |
| AU (1) | AU2005281859A1 (en) |
| BR (1) | BRPI0515186A (en) |
| CA (1) | CA2577861A1 (en) |
| DE (2) | DE102004044680B3 (en) |
| EA (1) | EA200700550A1 (en) |
| EC (1) | ECSP077306A (en) |
| ES (1) | ES2301056T3 (en) |
| GT (1) | GT200500241A (en) |
| IL (1) | IL181832A0 (en) |
| MX (1) | MX2007002833A (en) |
| NO (1) | NO20071805L (en) |
| PA (1) | PA8644701A1 (en) |
| PE (1) | PE20060596A1 (en) |
| RS (1) | RS20070095A (en) |
| SV (1) | SV2006002220A (en) |
| TW (1) | TW200621703A (en) |
| UY (1) | UY29109A1 (en) |
| WO (1) | WO2006027236A1 (en) |
| ZA (1) | ZA200701399B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| WO2005034939A1 (en) | 2003-10-08 | 2005-04-21 | Schering Aktiengesellschaft | 1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiphlogistics |
| US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102004063227A1 (en) * | 2004-12-22 | 2006-07-06 | Schering Ag | Tricylic amino alcohols, process for their preparation and their use as anti-inflammatory agents |
| EP1834948A1 (en) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiinflammatory drugs |
| EP1917963A1 (en) * | 2006-10-31 | 2008-05-07 | Bayer Schering Pharma Aktiengesellschaft | Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents |
| EP2129219A4 (en) | 2007-02-16 | 2012-08-29 | Synta Pharmaceuticals Corp | Substituted fused-ring compounds for inflammation and immune-related uses |
| EP2072509A1 (en) | 2007-12-18 | 2009-06-24 | Bayer Schering Pharma Aktiengesellschaft | 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996020930A1 (en) * | 1994-12-29 | 1996-07-11 | Allergan | Acetylenes disubstituted with a 5 or 8 substituted tetrahydronaphthyl or dihydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity |
| DE10038639A1 (en) * | 2000-07-28 | 2002-02-21 | Schering Ag | New and known N-aryl 2-hydroxy-omega-arylalkanamide derivatives, useful e.g. for treating inflammatory diseases such as rheumatism |
| US6903215B2 (en) * | 2002-03-26 | 2005-06-07 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| DE10215316C1 (en) * | 2002-04-02 | 2003-12-18 | Schering Ag | Quinoline and isoquinoline derivatives, a pharmaceutical agent and their use as anti-inflammatory agents |
| WO2005034939A1 (en) * | 2003-10-08 | 2005-04-21 | Schering Aktiengesellschaft | 1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiphlogistics |
-
2004
- 2004-09-09 DE DE102004044680A patent/DE102004044680B3/en not_active Expired - Fee Related
-
2005
- 2005-09-02 AT AT05786302T patent/ATE384069T1/en not_active IP Right Cessation
- 2005-09-02 GT GT200500241A patent/GT200500241A/en unknown
- 2005-09-02 ES ES05786302T patent/ES2301056T3/en active Active
- 2005-09-02 CN CNA2005800383722A patent/CN101065386A/en active Pending
- 2005-09-02 CA CA002577861A patent/CA2577861A1/en not_active Abandoned
- 2005-09-02 KR KR1020077005549A patent/KR20070050469A/en not_active Application Discontinuation
- 2005-09-02 DE DE502005002595T patent/DE502005002595D1/en not_active Expired - Fee Related
- 2005-09-02 BR BRPI0515186-4A patent/BRPI0515186A/en not_active Application Discontinuation
- 2005-09-02 RS RSP-2007/0095A patent/RS20070095A/en unknown
- 2005-09-02 EA EA200700550A patent/EA200700550A1/en unknown
- 2005-09-02 AU AU2005281859A patent/AU2005281859A1/en not_active Abandoned
- 2005-09-02 EP EP05786302A patent/EP1786823B1/en active Active
- 2005-09-02 WO PCT/EP2005/009623 patent/WO2006027236A1/en active IP Right Grant
- 2005-09-02 MX MX2007002833A patent/MX2007002833A/en not_active Application Discontinuation
- 2005-09-02 JP JP2007530646A patent/JP2008512416A/en not_active Withdrawn
- 2005-09-06 TW TW094130577A patent/TW200621703A/en unknown
- 2005-09-08 PA PA20058644701A patent/PA8644701A1/en unknown
- 2005-09-08 SV SV2005002220A patent/SV2006002220A/en not_active Application Discontinuation
- 2005-09-08 PE PE2005001041A patent/PE20060596A1/en not_active Application Discontinuation
- 2005-09-08 UY UY29109A patent/UY29109A1/en not_active Application Discontinuation
- 2005-09-09 AR ARP050103762A patent/AR050733A1/en unknown
-
2007
- 2007-02-16 ZA ZA200701399A patent/ZA200701399B/en unknown
- 2007-03-08 EC EC2007007306A patent/ECSP077306A/en unknown
- 2007-03-08 IL IL181832A patent/IL181832A0/en unknown
- 2007-04-03 NO NO20071805A patent/NO20071805L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP077306A (en) | 2007-04-26 |
| ZA200701399B (en) | 2008-09-25 |
| NO20071805L (en) | 2007-06-07 |
| DE102004044680B3 (en) | 2006-06-08 |
| CN101065386A (en) | 2007-10-31 |
| PE20060596A1 (en) | 2006-07-26 |
| AR050733A1 (en) | 2006-11-15 |
| EP1786823A1 (en) | 2007-05-23 |
| ATE384069T1 (en) | 2008-02-15 |
| AU2005281859A1 (en) | 2006-03-16 |
| TW200621703A (en) | 2006-07-01 |
| CA2577861A1 (en) | 2006-03-16 |
| UY29109A1 (en) | 2006-03-31 |
| ES2301056T3 (en) | 2008-06-16 |
| BRPI0515186A (en) | 2008-07-22 |
| GT200500241A (en) | 2006-08-17 |
| EA200700550A1 (en) | 2007-10-26 |
| DE502005002595D1 (en) | 2008-03-06 |
| SV2006002220A (en) | 2006-03-15 |
| EP1786823B1 (en) | 2008-01-16 |
| PA8644701A1 (en) | 2006-07-03 |
| RS20070095A (en) | 2008-11-28 |
| WO2006027236A1 (en) | 2006-03-16 |
| KR20070050469A (en) | 2007-05-15 |
| MX2007002833A (en) | 2007-07-09 |
| JP2008512416A (en) | 2008-04-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL179758A (en) | Substituted tetrahydro-2h-isoquinolin-1-one derivatives, method for the production thereof and use of the same as medicaments | |
| IL181832A0 (en) | Alkylidene tetrahydronaphthalene derivatives, method for their production and their use as anti-inflammatory agents | |
| IL172899A0 (en) | Heterocyclically substituted pentanol derivatives, method for the production thereof, and use thereof as anti-inflammatory agents | |
| IL181012A0 (en) | Substituted 8-aminoalkoxi-xanthines, method for the production thereof and use thereof as medicaments | |
| IL183060A0 (en) | Tricyclic aminoalcohols, methods for producing the same and their use as anti-inflammatory agents | |
| IL180874A0 (en) | Substituted, bicyclic 8-pyrrolidinoxanthines, method for the production thereof and their use as medicaments | |
| IL176913A0 (en) | 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments | |
| AU2006274834A8 (en) | Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives | |
| IL184901A0 (en) | 2,4-diamino-pyridopyrimidine derivatives and their use as mtor inhibitors | |
| IL177087A0 (en) | Controlled-release pharmaceutical composition and method for producing the same | |
| EP1967171A4 (en) | Skin patch and method of producing the same | |
| IL193155A0 (en) | Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents | |
| IL178887A0 (en) | Novel beta agonists, method for producing the same and their use as drugs | |
| IL182505A0 (en) | Purified phospholipid-non-steroidal, anti-inflammatory drug associated compositions and method for preparing and using same | |
| ZA200706672B (en) | 2,4-Diamino-pyridopyrimidine derivatives and their use as mTOR inhibitors | |
| PL377741A1 (en) | Diarylcycloalkyl derivatives, method for their production and their use as medicaments | |
| IL174975A0 (en) | 2-phenyl-benzofuran derivatives, method for the production thereof and their use | |
| PL366690A1 (en) | New derivatives of 4,5,6,7-tetrabromobenzimidazole and method for their obtaining | |
| HK1100946A1 (en) | 1-a-HALO-2,2-DIFLUORO-2-DEOXY-D-RIBOFURANOSE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | |
| PL380163A1 (en) | Method for the obtaining 1, 2-diaminopropane and polypropyleneamines | |
| IL181339A0 (en) | Method for the production of diarylcycloalkyl derivatives | |
| GB0625794D0 (en) | Condom and process for producing the same | |
| EP1781678A4 (en) | 1-alpha-halo-2,2-difluoro-2-deoxy-d-ribofuranose derivatives and process for the preparation thereof | |
| IL187419A0 (en) | Heteroarylethenyl derivatives, their manufacture and use as pharmaceutical agents | |
| IL178521A0 (en) | Process for the preparation of substituted tetralin and substituted indane derivatives |