JP2008510719A5 - - Google Patents
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- Publication number
- JP2008510719A5 JP2008510719A5 JP2007528037A JP2007528037A JP2008510719A5 JP 2008510719 A5 JP2008510719 A5 JP 2008510719A5 JP 2007528037 A JP2007528037 A JP 2007528037A JP 2007528037 A JP2007528037 A JP 2007528037A JP 2008510719 A5 JP2008510719 A5 JP 2008510719A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- piperidin
- methyl
- pharmaceutically acceptable
- ylmethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60296804P | 2004-08-19 | 2004-08-19 | |
| PCT/US2005/029518 WO2006021002A2 (en) | 2004-08-19 | 2005-08-18 | Compounds useful for inhibiting chk1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008510719A JP2008510719A (ja) | 2008-04-10 |
| JP2008510719A5 true JP2008510719A5 (https=) | 2008-10-02 |
Family
ID=35744692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007528037A Pending JP2008510719A (ja) | 2004-08-19 | 2005-08-18 | Ｃｈｋ１の阻害に有用な化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080318974A1 (https=) |
| EP (1) | EP1778648A2 (https=) |
| JP (1) | JP2008510719A (https=) |
| KR (1) | KR20070054205A (https=) |
| CN (1) | CN101115727A (https=) |
| AU (1) | AU2005272586A1 (https=) |
| BR (1) | BRPI0514466A (https=) |
| CA (1) | CA2577880A1 (https=) |
| MX (1) | MX2007002040A (https=) |
| WO (1) | WO2006021002A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201008005D0 (en) | 2010-05-13 | 2010-06-30 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| GB201119799D0 (en) | 2011-11-16 | 2011-12-28 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| GB201402277D0 (en) | 2014-02-10 | 2014-03-26 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| EP3778584A1 (en) | 2014-06-19 | 2021-02-17 | ARIAD Pharmaceuticals, Inc. | Production process of 2-chloro-4-heteroaryl-pyrimidine derivatives |
| CN104628659A (zh) * | 2015-01-27 | 2015-05-20 | 广西师范大学 | 具有抗肿瘤作用的吡嗪-芳基脲衍生物及其制备方法与应用 |
| MX2018008507A (es) | 2016-01-11 | 2019-07-04 | Merrimack Pharmaceuticals Inc | Inhibición de proteína relacionada con ataxia telangiectasia y rad3 (atr). |
| CN108601781B (zh) | 2016-02-04 | 2019-11-22 | 广州必贝特医药技术有限公司 | 作为检测点激酶1(chk1)抑制剂的3,5-二取代吡唑及其制备及应用 |
| CN110678169A (zh) | 2017-03-31 | 2020-01-10 | 西雅图遗传学公司 | Chk1-抑制剂与weel-抑制剂的组合 |
| JP2021523208A (ja) | 2018-05-14 | 2021-09-02 | アリアド ファーマシューティカルズ， インコーポレイテッド | ピリミジン誘導体の医薬塩及び障害の処置方法 |
| CN112457306A (zh) | 2019-09-06 | 2021-03-09 | 上海瑛派药业有限公司 | 3,5-二取代吡唑化合物作为激酶抑制剂及其应用 |
| US11634424B2 (en) * | 2019-11-29 | 2023-04-25 | Medshine Discovery Inc. | Diazaindole derivative and use thereof as CHK1 inhibitor |
| WO2021119236A1 (en) | 2019-12-10 | 2021-06-17 | Seagen Inc. | Preparation of a chk1 inhibitor compound |
| GB202107924D0 (en) | 2021-06-03 | 2021-07-21 | Sentinel Oncology Ltd | A pharmaceutical salt |
| GB202107932D0 (en) | 2021-06-03 | 2021-07-21 | Sentinel Oncology Ltd | Preparation of a CHK1 Inhibitor Compound |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL254871A (https=) * | 1959-08-14 | |||
| CH152169A4 (https=) * | 1969-01-31 | 1970-11-13 | ||
| US4071524A (en) * | 1976-11-08 | 1978-01-31 | Riker Laboratories, Inc. | Derivatives of urea |
| CN1213022C (zh) * | 1997-12-22 | 2005-08-03 | 拜尔有限公司 | 用对称和不对称的取代二苯脲抑制raf激酶 |
| UA76977C2 (en) * | 2001-03-02 | 2006-10-16 | Icos Corp | Aryl- and heteroaryl substituted chk1 inhibitors and their use as radiosensitizers and chemosensitizers |
| EP1501514B1 (en) * | 2002-05-03 | 2012-12-19 | Exelixis, Inc. | Protein kinase modulators and methods of use |
| AU2004274013A1 (en) * | 2003-09-17 | 2005-03-31 | Icos Corporation | Use of Chk1 inhibitors to control cell proliferation |
| KR20070028591A (ko) * | 2004-06-25 | 2007-03-12 | 이코스 코포레이션 | Ｃｈｋ1의 억제에 유용한 비스아릴우레아 유도체 |
| MX2007000265A (es) * | 2004-07-02 | 2007-07-20 | Icos Corp | Compuestos utiles para inhibir chk1. |
-
2005
- 2005-08-18 EP EP05810303A patent/EP1778648A2/en not_active Withdrawn
- 2005-08-18 JP JP2007528037A patent/JP2008510719A/ja active Pending
- 2005-08-18 CN CNA2005800353820A patent/CN101115727A/zh active Pending
- 2005-08-18 BR BRPI0514466-3A patent/BRPI0514466A/pt not_active IP Right Cessation
- 2005-08-18 MX MX2007002040A patent/MX2007002040A/es not_active Application Discontinuation
- 2005-08-18 WO PCT/US2005/029518 patent/WO2006021002A2/en not_active Ceased
- 2005-08-18 AU AU2005272586A patent/AU2005272586A1/en not_active Abandoned
- 2005-08-18 US US11/659,389 patent/US20080318974A1/en not_active Abandoned
- 2005-08-18 CA CA002577880A patent/CA2577880A1/en not_active Abandoned
- 2005-08-18 KR KR1020077006216A patent/KR20070054205A/ko not_active Withdrawn