JP2008509987A - トリアゾロピリジン化合物 - Google Patents

トリアゾロピリジン化合物 Download PDF

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Publication number
JP2008509987A
JP2008509987A JP2007526616A JP2007526616A JP2008509987A JP 2008509987 A JP2008509987 A JP 2008509987A JP 2007526616 A JP2007526616 A JP 2007526616A JP 2007526616 A JP2007526616 A JP 2007526616A JP 2008509987 A JP2008509987 A JP 2008509987A
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triazolo
alkyl
difluorophenyl
group
thio
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JP2008509987A5 (https=
Inventor
ヴィ． ラッカー ポール
ディウェイン ジェロ−ム ケヴィン
ラジュ セルネス シャウン
エドワード バルダス ジョン
シング リ
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ファルマシア アンド アップジョン カンパニー リミテッド ライアビリティ カンパニー
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Publication of JP2008509987A publication Critical patent/JP2008509987A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
JP2007526616A 2004-08-18 2005-08-08 トリアゾロピリジン化合物 Withdrawn JP2008509987A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60234404P 2004-08-18 2004-08-18
PCT/IB2005/002868 WO2006018735A2 (en) 2004-08-18 2005-08-08 Triazolopyridine compounds

Publications (2)

Publication Number Publication Date
JP2008509987A true JP2008509987A (ja) 2008-04-03
JP2008509987A5 JP2008509987A5 (https=) 2008-09-11

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ID=35735197

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007526616A Withdrawn JP2008509987A (ja) 2004-08-18 2005-08-08 トリアゾロピリジン化合物

Country Status (7)

Country Link
US (1) US20090209577A1 (https=)
EP (1) EP1786811A2 (https=)
JP (1) JP2008509987A (https=)
BR (1) BRPI0514327A (https=)
CA (1) CA2577478A1 (https=)
MX (1) MX2007002050A (https=)
WO (1) WO2006018735A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017531037A (ja) * 2014-10-06 2017-10-19 フラットレー ディスカバリー ラブ，エルエルシー トリアゾロピリジン化合物および嚢胞性線維症の治療のための方法
JP2023507610A (ja) * 2019-12-19 2023-02-24 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ Ｃｄ２０６モジュレーター、その使用、および調製方法

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0514391A (pt) * 2004-08-18 2008-06-10 Pharmacia & Upjohn Co Llc compostos de triazolopiridina para o tratamento de inflamação
US7579360B2 (en) 2005-06-09 2009-08-25 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
US7572807B2 (en) 2005-06-09 2009-08-11 Bristol-Myers Squibb Company Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
JP5336375B2 (ja) * 2006-08-30 2013-11-06 セルゾーム リミテッド キナーゼ阻害剤としてのトリアゾール誘導体
EP1894931A1 (en) * 2006-08-30 2008-03-05 Cellzome Ag Triazole derivatives as kinase inhibitors
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
US8119658B2 (en) 2007-10-01 2012-02-21 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
MX2010005700A (es) 2007-11-27 2010-06-11 Cellzome Ltd Amino triazoles como inhibidores pi3k.
JO3041B1 (ar) 2008-07-25 2016-09-05 Galapagos Nv مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
WO2010010184A1 (en) * 2008-07-25 2010-01-28 Galapagos Nv [1, 2, 4] triazolo [1, 5-a] pyridines as jak inhibitors
TWI453207B (zh) 2008-09-08 2014-09-21 Signal Pharm Llc 胺基三唑并吡啶，其組合物及使用其之治療方法
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