JP2008509089A5 - - Google Patents
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- Publication number
- JP2008509089A5 JP2008509089A5 JP2007516731A JP2007516731A JP2008509089A5 JP 2008509089 A5 JP2008509089 A5 JP 2008509089A5 JP 2007516731 A JP2007516731 A JP 2007516731A JP 2007516731 A JP2007516731 A JP 2007516731A JP 2008509089 A5 JP2008509089 A5 JP 2008509089A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- solid dosage
- oral solid
- immediate
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58124404P | 2004-06-17 | 2004-06-17 | |
| US60/581,244 | 2004-06-17 | ||
| PCT/US2005/021284 WO2006096194A2 (en) | 2004-06-17 | 2005-06-16 | Drinkable immediate release tablet made with direct compression of memantine or neramexane |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008509089A JP2008509089A (ja) | 2008-03-27 |
| JP2008509089A5 true JP2008509089A5 (https=) | 2011-01-27 |
| JP5025468B2 JP5025468B2 (ja) | 2012-09-12 |
Family
ID=36953777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516731A Expired - Lifetime JP5025468B2 (ja) | 2004-06-17 | 2005-06-16 | メマンチン又はネラメキサンの直接圧縮によって製造された、飲用に適した即効型錠剤 |
Country Status (11)
| Country | Link |
|---|---|
| EP (3) | EP2601937A1 (https=) |
| JP (1) | JP5025468B2 (https=) |
| KR (1) | KR20090033410A (https=) |
| CN (1) | CN101389315A (https=) |
| AU (1) | AU2005328701B2 (https=) |
| BR (1) | BRPI0512263A (https=) |
| CA (1) | CA2568445C (https=) |
| EA (1) | EA011290B1 (https=) |
| ES (1) | ES2483126T3 (https=) |
| IL (1) | IL179992A (https=) |
| WO (1) | WO2006096194A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2548552B1 (en) * | 2007-09-12 | 2015-11-18 | Merz Pharma GmbH & Co. KGaA | Titration package for 1-amino-alkylcyclohexanes |
| HRP20130485T1 (en) * | 2009-06-29 | 2013-06-30 | Merz Pharma Gmbh & Co. Kgaa | Method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane |
| JP5749260B2 (ja) * | 2009-06-29 | 2015-07-15 | メルツ・ファルマ・ゲーエムベーハー・ウント・コ・カーゲーアーアー | ネラメキサンの製造方法 |
| HRP20130486T1 (en) * | 2009-06-29 | 2013-06-30 | Merz Pharma Gmbh & Co. Kgaa | Method of preparing neramexane |
| EP2316434A1 (en) * | 2009-10-22 | 2011-05-04 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Orally disintegrating tablets of memantine |
| US20110294890A1 (en) * | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
| EP2585049A1 (en) * | 2010-06-24 | 2013-05-01 | Merz Pharma GmbH & Co. KGaA | Neramexane multiple unit dosage form |
| WO2012048871A1 (en) | 2010-10-12 | 2012-04-19 | Merz Pharma Gmbh & Co. Kgaa | Memantine for improving cognitive performance in subjects |
| EP2627323A4 (en) | 2010-10-12 | 2014-03-12 | Univ Johns Hopkins | HUSTENSTILLENDE COMPOSITIONS WITH MEMANTINE |
| EP2526925A1 (en) | 2011-05-23 | 2012-11-28 | Deva Holding Anonim Sirketi | A dose adjustable oral pump spray or aerosol spray containing memantine |
| CN107334744B (zh) * | 2017-07-24 | 2020-09-04 | 湖南洞庭药业股份有限公司 | 盐酸美金刚药物组合物和制法 |
| BR112021024054A2 (pt) * | 2019-05-31 | 2022-01-11 | Tecnimede Sociedade Tecnico Medicinal Sa | Composições farmacêuticas de combinação de dose fixa de liberação imediata, seus métodos e usos. |
| CN114199812A (zh) * | 2021-12-28 | 2022-03-18 | 南通联亚药业有限公司 | 一种盐酸美金刚缓释制剂中盐酸美金刚的检测方法 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES413944A1 (es) | 1972-04-20 | 1976-06-01 | Merz & Co | Procedimiento para la preparacion de compuestos de adamen- tano trisustituidos en las posiciones 1,3,5. |
| DE2856393C2 (de) | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
| US4346112A (en) * | 1981-06-29 | 1982-08-24 | University Patents Inc. | Composition and method for treating patients having Parkinson's Disease |
| JPS6216413A (ja) * | 1985-07-12 | 1987-01-24 | Teijin Ltd | キチン類誘導体を用いた徐放性医薬品組成物 |
| US5506231A (en) | 1989-03-31 | 1996-04-09 | The Children's Medical Center Corporation | Treatment of aids dementia, myelopathy and blindness |
| US5334618A (en) | 1991-04-04 | 1994-08-02 | The Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| ES2059602T3 (es) * | 1989-04-14 | 1994-11-16 | Merz & Co Gmbh & Co | Uso de derivados de adamantano para la prevencion y tratamiento de isquemia cerebral. |
| DE4014672A1 (de) * | 1990-05-08 | 1991-11-14 | Werner E G Prof Dr Mueller | Verwendung von adamantan-derivaten zur zytoprotektion von nicht-infizierten und virus-infizierten lymphozyten als auch anderen zelltypen |
| US5455279A (en) | 1991-04-19 | 1995-10-03 | The Children's Medical Center Corporation | Regimen method of mediating neuronal damage using nitroglycerine |
| US5614560A (en) | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| WO1992018112A1 (en) | 1991-04-19 | 1992-10-29 | The Children's Medical Center Corporation | Method of preventing nmda receptor complex-mediated neuronal damage |
| DE4225730C2 (de) | 1992-08-04 | 2003-04-30 | Merz Pharma Gmbh & Co Kgaa | Verfahren zur Herstellung von festen Arzneiformkörpern mit protrahierter 2-Stufen-Freisetzung |
| GB9517062D0 (en) * | 1995-08-18 | 1995-10-25 | Scherer Ltd R P | Pharmaceutical compositions |
| JPH0971523A (ja) * | 1995-09-07 | 1997-03-18 | Riyuukakusan:Kk | 口腔内で崩壊性の速い錠剤 |
| AUPN605795A0 (en) * | 1995-10-19 | 1995-11-09 | F.H. Faulding & Co. Limited | Analgesic pharmaceutical composition |
| KR100630506B1 (ko) * | 1997-06-30 | 2006-09-29 | 메르츠 파마 게엠베하 운트 코. 카가아 | Nmda 수용체 길항물질로서의 1-아미노-알킬시클로헥산 화합물, 이를 함유하는 제약학적 조성물 및 이것으로 치료하는 방법 |
| US6071966A (en) | 1997-06-30 | 2000-06-06 | Merz + Co. Gmbh & Co. | 1-amino-alkylcyclohexane NMDA receptor antagonists |
| US6413556B1 (en) | 1999-01-08 | 2002-07-02 | Sky High, Llc | Aqueous anti-apoptotic compositions |
| SE9901077D0 (sv) | 1999-03-23 | 1999-03-23 | Astra Ab | Novel use |
| US6444702B1 (en) | 2000-02-22 | 2002-09-03 | Neuromolecular, Inc. | Aminoadamantane derivatives as therapeutic agents |
| TW593223B (en) * | 2000-06-20 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists |
| US6828462B2 (en) | 2001-11-07 | 2004-12-07 | Merz Pharma Gmbh & Co. Kgaa | Unsaturated 1-amino-alkylcyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists |
| EP1471909A4 (en) * | 2002-01-16 | 2007-07-25 | Endo Pharmaceuticals Inc | PHARMACEUTICAL COMPOSITION AND METHOD FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM |
| TW200306189A (en) | 2002-03-21 | 2003-11-16 | Merz Pharma Gmbh & Co Kgaa | Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists |
| FR2841138B1 (fr) * | 2002-06-25 | 2005-02-25 | Cll Pharma | Composition pharmaceutique solide contenant un principe actif lipophile, son procede de preparation |
| US20040127541A1 (en) * | 2002-07-31 | 2004-07-01 | Janet Codd | Bicifadine formulation |
| MXPA05012810A (es) * | 2003-06-16 | 2006-02-13 | Allergan Inc | Formas de dosis oral de memantina. |
| AR046314A1 (es) * | 2003-11-05 | 2005-11-30 | Merz Pharma Gmbh & Co Kgaa | Composiciones que comprenden ciclohexilaminas y aminoadamantanos |
| RU2766487C2 (ru) * | 2004-01-20 | 2022-03-15 | Новартис Аг | Композиция и способ прямого прессования |
| EP1715843A1 (en) * | 2004-01-29 | 2006-11-02 | Neuromolecular Inc. | Combination of a nmda receptor antagonist and a mao-inhibitor or a gadph-inhibitor for the treatment of central nervous system-related conditions |
| GT200600008A (es) * | 2005-01-18 | 2006-08-09 | Formulacion de compresion directa y proceso |
-
2005
- 2005-06-16 JP JP2007516731A patent/JP5025468B2/ja not_active Expired - Lifetime
- 2005-06-16 CA CA2568445A patent/CA2568445C/en not_active Expired - Fee Related
- 2005-06-16 EA EA200700055A patent/EA011290B1/ru not_active IP Right Cessation
- 2005-06-16 CN CNA2005800198789A patent/CN101389315A/zh active Pending
- 2005-06-16 WO PCT/US2005/021284 patent/WO2006096194A2/en not_active Ceased
- 2005-06-16 ES ES11179637.1T patent/ES2483126T3/es not_active Expired - Lifetime
- 2005-06-16 EP EP13153135.2A patent/EP2601937A1/en not_active Withdrawn
- 2005-06-16 AU AU2005328701A patent/AU2005328701B2/en not_active Ceased
- 2005-06-16 KR KR1020097005872A patent/KR20090033410A/ko not_active Withdrawn
- 2005-06-16 EP EP11179637.1A patent/EP2397122B1/en not_active Expired - Lifetime
- 2005-06-16 BR BRPI0512263-5A patent/BRPI0512263A/pt not_active IP Right Cessation
- 2005-06-16 EP EP05857458A patent/EP1765287A2/en not_active Withdrawn
-
2006
- 2006-12-11 IL IL179992A patent/IL179992A/en not_active IP Right Cessation
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