JP2008508365A5 - - Google Patents

Download PDF

Info

Publication number
JP2008508365A5
JP2008508365A5 JP2007554065A JP2007554065A JP2008508365A5 JP 2008508365 A5 JP2008508365 A5 JP 2008508365A5 JP 2007554065 A JP2007554065 A JP 2007554065A JP 2007554065 A JP2007554065 A JP 2007554065A JP 2008508365 A5 JP2008508365 A5 JP 2008508365A5
Authority
JP
Japan
Prior art keywords
alkyl
hexahydroindeno
pyrrole
methyl
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007554065A
Other languages
English (en)
Japanese (ja)
Other versions
JP4990164B2 (ja
JP2008508365A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/026415 external-priority patent/WO2007081299A2/en
Publication of JP2008508365A publication Critical patent/JP2008508365A/ja
Publication of JP2008508365A5 publication Critical patent/JP2008508365A5/ja
Application granted granted Critical
Publication of JP4990164B2 publication Critical patent/JP4990164B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2007554065A 2004-07-29 2005-07-26 セロトニン受容体モジュレーターとしての三環系インデノ−ピロール誘導体 Expired - Fee Related JP4990164B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59204704P 2004-07-29 2004-07-29
US60/592,047 2004-07-29
PCT/US2005/026415 WO2007081299A2 (en) 2004-07-29 2005-07-26 Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators

Publications (3)

Publication Number Publication Date
JP2008508365A JP2008508365A (ja) 2008-03-21
JP2008508365A5 true JP2008508365A5 (enExample) 2008-06-05
JP4990164B2 JP4990164B2 (ja) 2012-08-01

Family

ID=37075566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007554065A Expired - Fee Related JP4990164B2 (ja) 2004-07-29 2005-07-26 セロトニン受容体モジュレーターとしての三環系インデノ−ピロール誘導体

Country Status (16)

Country Link
US (5) US20060025601A1 (enExample)
EP (1) EP1841738A4 (enExample)
JP (1) JP4990164B2 (enExample)
KR (2) KR101257233B1 (enExample)
CN (1) CN101516372A (enExample)
AR (1) AR050274A1 (enExample)
AU (1) AU2005333518B2 (enExample)
BR (1) BRPI0512869A (enExample)
CA (1) CA2603249C (enExample)
IL (1) IL180977A (enExample)
NO (1) NO20071102L (enExample)
NZ (1) NZ552806A (enExample)
RU (1) RU2007107494A (enExample)
TW (1) TWI377195B (enExample)
WO (1) WO2007081299A2 (enExample)
ZA (1) ZA200700684B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081299A2 (en) * 2004-07-29 2007-07-19 Athersys, Inc. Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators
EP2742936A1 (en) 2006-05-16 2014-06-18 Takeda Pharmaceutical Company Limited Fused heterocyclic compound and use thereof
CA2677661A1 (en) 2007-02-07 2008-08-14 Kyowa Hakko Kirin Co., Ltd. Tricyclic compounds
US20100266504A1 (en) 2007-11-15 2010-10-21 Takahiro Matsumoto Condensed pyridine derivative and use thereof
WO2009097995A1 (de) * 2008-02-07 2009-08-13 Sanofi-Aventis Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8486980B2 (en) 2008-08-06 2013-07-16 Kyowa Hakko Kirin Co., Ltd. Tricyclic compound
TW201041851A (en) 2009-03-10 2010-12-01 Organon Nv Tricyclic heterocyclic derivatives
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
CN106380440B (zh) * 2016-08-30 2019-02-01 华东师范大学 一种茚酮并吡咯类衍生物及其合成方法和应用
CN106631989B (zh) * 2016-11-26 2019-07-16 威海迪素制药有限公司 一种盐酸多奈哌齐有关物质e的制备方法
US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3576334D1 (de) * 1984-07-25 1990-04-12 Abbott Lab 1,2,3,3a,8,8a-hexahydro-indeno-(1,2-c)pyrrde.
US4622405A (en) * 1984-07-25 1986-11-11 Abbott Laboratories 1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrroles useful in the treatment of hypertension
KR910700251A (ko) * 1988-12-15 1991-03-14 원본미기재 5-ht 선택제
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
US5244888A (en) * 1989-11-17 1993-09-14 Abbott Laboratories 5-HT selective agents
TW334423B (en) * 1993-10-22 1998-06-21 Hoffmann La Roche Tricyclic 1-aminoethylpyrrole-derivatives
US7351711B2 (en) * 2003-07-31 2008-04-01 Janssen Pharmaceutical, N.V. Tricyclic indanyls as integrin inhibitors
TWI350168B (en) * 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
WO2007081299A2 (en) * 2004-07-29 2007-07-19 Athersys, Inc. Tricyclic indeno-pyrrole derivatives as serotonin receptor modulators

Similar Documents

Publication Publication Date Title
JP2008508365A5 (enExample)
JP2013509392A5 (enExample)
JP2006500370A5 (enExample)
JP2008513498A5 (enExample)
RU2004130488A (ru) Пиримидиновые производные
JP2009536620A5 (enExample)
RU2011108281A (ru) Трипиридилкарбоксамидные антагонисты орексиновых рецепторов
RU2003129638A (ru) Новые соединения
WO2001058869A3 (en) Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
CA2334298A1 (en) Neuropeptide y5 receptor antagonists
JP2017533968A5 (enExample)
JP2008509187A5 (enExample)
JP2008526999A5 (enExample)
JP2013510178A5 (enExample)
WO2010014613A3 (en) Treating various disorders using trkb agonists
JP2002030084A5 (enExample)
RU2017101829A (ru) Пиразоловые соединения в качестве модуляторов fshr и пути их применения
JP2007507494A5 (enExample)
CA2657106A1 (en) Aminoindane derivative or salt thereof
JP2016503785A5 (enExample)
JP2015522018A5 (enExample)
RU2007130144A (ru) Гетероциклические соединения в качестве антагонистов cccr2b
JP2003513071A5 (enExample)
RU2007107494A (ru) Трициклические производные инденопиррола как модуляторы серотининовых рецепторов, фармацевтическая композиция на их основе и способ лечения заболеваний, растройств и/или патологических состояний, связанных с необходимостью модуляции функции 5-нт2с рецепторов
JP2004525184A5 (enExample)