JP2008507300A5 - - Google Patents

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Publication number
JP2008507300A5
JP2008507300A5 JP2007529867A JP2007529867A JP2008507300A5 JP 2008507300 A5 JP2008507300 A5 JP 2008507300A5 JP 2007529867 A JP2007529867 A JP 2007529867A JP 2007529867 A JP2007529867 A JP 2007529867A JP 2008507300 A5 JP2008507300 A5 JP 2008507300A5
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JP
Japan
Prior art keywords
bcl
host cell
inhibitor
cell
recombinant protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007529867A
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English (en)
Japanese (ja)
Other versions
JP5378682B2 (ja
JP2008507300A (ja
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Publication date
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Priority claimed from PCT/US2005/026224 external-priority patent/WO2007015691A2/en
Publication of JP2008507300A publication Critical patent/JP2008507300A/ja
Publication of JP2008507300A5 publication Critical patent/JP2008507300A5/ja
Application granted granted Critical
Publication of JP5378682B2 publication Critical patent/JP5378682B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007529867A 2004-07-23 2005-07-25 細胞培養物の寿命および由来するタンパク質の収率を増加させるための方法および組成物 Expired - Lifetime JP5378682B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59034904P 2004-07-23 2004-07-23
US60/590,349 2004-07-23
PCT/US2005/026224 WO2007015691A2 (en) 2004-07-23 2005-07-25 Methods and compositions for increasing longevity and protein yield from a cell culture

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012163611A Division JP2012254084A (ja) 2004-07-23 2012-07-24 細胞培養物の寿命および由来するタンパク質の収率を増加させるための方法および組成物

Publications (3)

Publication Number Publication Date
JP2008507300A JP2008507300A (ja) 2008-03-13
JP2008507300A5 true JP2008507300A5 (enExample) 2008-07-31
JP5378682B2 JP5378682B2 (ja) 2013-12-25

Family

ID=37709023

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007529867A Expired - Lifetime JP5378682B2 (ja) 2004-07-23 2005-07-25 細胞培養物の寿命および由来するタンパク質の収率を増加させるための方法および組成物
JP2012163611A Pending JP2012254084A (ja) 2004-07-23 2012-07-24 細胞培養物の寿命および由来するタンパク質の収率を増加させるための方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012163611A Pending JP2012254084A (ja) 2004-07-23 2012-07-24 細胞培養物の寿命および由来するタンパク質の収率を増加させるための方法および組成物

Country Status (5)

Country Link
EP (1) EP1802646B1 (enExample)
JP (2) JP5378682B2 (enExample)
CA (1) CA2576464C (enExample)
SG (1) SG163592A1 (enExample)
WO (1) WO2007015691A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7537930B2 (en) 2004-07-23 2009-05-26 Immunomedics, Inc. Mammalian cell lines for increasing longevity and protein yield from a cell culture
KR101794638B1 (ko) * 2008-06-10 2017-12-04 상가모 테라퓨틱스, 인코포레이티드 Ｂａｘ- 및 ｂａｋ-결함 세포주들의 제조 방법 및 조성물
JP5665065B2 (ja) * 2011-04-28 2015-02-04 国立大学法人大阪大学 リソソーム病治療用医薬組成物
US9365825B2 (en) * 2013-03-11 2016-06-14 Taiga Biotechnologies, Inc. Expansion of adult stem cells in vitro
EP2970915B1 (en) * 2013-03-15 2019-08-14 Maxcyte, Inc. Methods and compositions for generating stable transfected cells
KR20170135966A (ko) 2015-04-13 2017-12-08 맥스시티 인코포레이티드 게놈 dna를 변형시키기 위한 방법 및 조성물
GB201511196D0 (en) * 2015-06-25 2015-08-12 Cytosystems Ltd Monoclonal antibodies
CN111808822B (zh) * 2020-07-02 2024-01-12 北京百普赛斯生物科技股份有限公司 细胞培养用补料液及提高重组hek293细胞蛋白表达量的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0471484A (ja) * 1990-07-11 1992-03-06 Teijin Ltd 低凝集性細胞及びその培養方法
AU7614600A (en) * 1999-09-27 2001-04-30 Genentech Inc. Methods for making recombinant proteins using apoptosis inhibitors
US7604989B2 (en) * 2001-07-10 2009-10-20 Johns Hopkins University Inhibition of apoptosis process and improvement of cell performance
WO2003040374A1 (en) * 2001-11-02 2003-05-15 Centocor, Inc. METHODS AND COMPOSITIONS FOR ENHANCED PROTEIN EXPRESSION AND/OR GROWTH OF CULTURED CELLS USING CO-TRANSCRIPTION OF A Bcl2 ENCODING NUCLEIC ACID
US6964199B2 (en) * 2001-11-02 2005-11-15 Cantocor, Inc. Methods and compositions for enhanced protein expression and/or growth of cultured cells using co-transcription of a Bcl2 encoding nucleic acid
EP1490481A4 (en) * 2001-12-14 2005-12-07 Centocor Inc CLONAL CELL LINES OF MYELOMES FOR PRODUCING PROTEINS IN A CHEMICALLY DEFINED ENVIRONMENT
US20030219871A1 (en) * 2002-03-28 2003-11-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Host cells having improved cell survival properties and methods to generate such cells
US7537930B2 (en) * 2004-07-23 2009-05-26 Immunomedics, Inc. Mammalian cell lines for increasing longevity and protein yield from a cell culture

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