EP1490481A4 - Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media - Google Patents

Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media

Info

Publication number
EP1490481A4
EP1490481A4 EP02797264A EP02797264A EP1490481A4 EP 1490481 A4 EP1490481 A4 EP 1490481A4 EP 02797264 A EP02797264 A EP 02797264A EP 02797264 A EP02797264 A EP 02797264A EP 1490481 A4 EP1490481 A4 EP 1490481A4
Authority
EP
European Patent Office
Prior art keywords
cell lines
myeloma cell
chemically defined
defined media
lines useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02797264A
Other languages
German (de)
French (fr)
Other versions
EP1490481A2 (en
Inventor
Chichang Lee
Celia Ly
Gordon Moore
Edward Savino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of EP1490481A2 publication Critical patent/EP1490481A2/en
Publication of EP1490481A4 publication Critical patent/EP1490481A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/95—Protein-free medium and culture conditions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
EP02797264A 2001-12-14 2002-12-11 Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media Withdrawn EP1490481A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33942901P 2001-12-14 2001-12-14
US339429P 2001-12-14
PCT/US2002/039496 WO2003052064A2 (en) 2001-12-14 2002-12-11 Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media

Publications (2)

Publication Number Publication Date
EP1490481A2 EP1490481A2 (en) 2004-12-29
EP1490481A4 true EP1490481A4 (en) 2005-12-07

Family

ID=23328968

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02797264A Withdrawn EP1490481A4 (en) 2001-12-14 2002-12-11 Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media

Country Status (5)

Country Link
EP (1) EP1490481A4 (en)
JP (1) JP2005512538A (en)
AU (1) AU2002362130A1 (en)
CA (1) CA2470026A1 (en)
WO (1) WO2003052064A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005083060A1 (en) * 2004-03-01 2005-09-09 Kitakyushu Foundation For The Advancement Of Industry, Science And Technology Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens
US7531327B2 (en) * 2004-07-23 2009-05-12 Immunomedics, Inc. Methods and compositions for increasing longevity and protein yield from a cell culture
CA2576464C (en) * 2004-07-23 2014-09-09 Immunomedics, Inc. Methods and compositions for increasing longevity and protein yield from a cell culture
MY187936A (en) * 2013-03-15 2021-10-29 In3Bio Ltd Self-assembling synthetic proteins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002066603A2 (en) * 2001-02-15 2002-08-29 Centocor, Inc. Chemically defined medium for cultured mammalian cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI831484L (en) * 1982-05-05 1983-11-06 Genentech Inc PLASMINOGEN AKTIVATOR FOER MAENSKOVAEVNAD
DE3363830D1 (en) * 1982-12-21 1986-07-03 Ferring Ab Vasotocin derivatives
DK585886A (en) * 1985-12-24 1987-06-25 Takeda Chemical Industries Ltd IMMUNSTIMENTAL AGENTS AND USE THEREOF
US5199942A (en) * 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation
EP0732933B1 (en) * 1993-11-15 2002-10-09 Celtrix Pharmaceuticals, Inc. Use of igf-1 and igfbp-3 in the manufacture of a medicament for treating a renal disorder
US5770565A (en) * 1994-04-13 1998-06-23 La Jolla Cancer Research Center Peptides for reducing or inhibiting bone resorption
US5677275A (en) * 1994-08-05 1997-10-14 The United States Of America As Represented By The Department Of Health And Human Services Treatment of cancer with human chorionic gonadotropin
EP0880356A4 (en) * 1996-02-16 2002-03-27 Univ California Antimicrobial peptides and methods of use
US6075123A (en) * 1996-06-03 2000-06-13 St. Jude Children's Research Hospital Cyclin-C variants, and diagnostic and therapeutic uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002066603A2 (en) * 2001-02-15 2002-08-29 Centocor, Inc. Chemically defined medium for cultured mammalian cells

Also Published As

Publication number Publication date
JP2005512538A (en) 2005-05-12
AU2002362130A1 (en) 2003-06-30
WO2003052064A3 (en) 2004-10-28
WO2003052064A2 (en) 2003-06-26
CA2470026A1 (en) 2003-06-26
EP1490481A2 (en) 2004-12-29

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20040713

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12N 15/85 B

Ipc: 7C 12N 15/00 B

Ipc: 7C 12N 5/10 A

A4 Supplementary search report drawn up and despatched

Effective date: 20051024

17Q First examination report despatched

Effective date: 20070823

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080304