SG163592A1 - Methods and compositions for increasing longevity and protein yield from a cell culture - Google Patents
Methods and compositions for increasing longevity and protein yield from a cell cultureInfo
- Publication number
- SG163592A1 SG163592A1 SG201004954-2A SG2010049542A SG163592A1 SG 163592 A1 SG163592 A1 SG 163592A1 SG 2010049542 A SG2010049542 A SG 2010049542A SG 163592 A1 SG163592 A1 SG 163592A1
- Authority
- SG
- Singapore
- Prior art keywords
- cells
- culture
- compositions
- methods
- cell culture
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 6
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000014150 Interferons Human genes 0.000 abstract 2
- 108010050904 Interferons Proteins 0.000 abstract 2
- 102000015696 Interleukins Human genes 0.000 abstract 2
- 108010063738 Interleukins Proteins 0.000 abstract 2
- 239000003102 growth factor Substances 0.000 abstract 2
- 229940088597 hormone Drugs 0.000 abstract 2
- 239000005556 hormone Substances 0.000 abstract 2
- 229940047124 interferons Drugs 0.000 abstract 2
- 229940047122 interleukins Drugs 0.000 abstract 2
- 230000014616 translation Effects 0.000 abstract 2
- 229940088872 Apoptosis inhibitor Drugs 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- -1 antibodies Proteins 0.000 abstract 1
- 239000000158 apoptosis inhibitor Substances 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 229940088598 enzyme Drugs 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59034904P | 2004-07-23 | 2004-07-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG163592A1 true SG163592A1 (en) | 2010-08-30 |
Family
ID=37709023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG201004954-2A SG163592A1 (en) | 2004-07-23 | 2005-07-25 | Methods and compositions for increasing longevity and protein yield from a cell culture |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1802646B1 (enExample) |
| JP (2) | JP5378682B2 (enExample) |
| CA (1) | CA2576464C (enExample) |
| SG (1) | SG163592A1 (enExample) |
| WO (1) | WO2007015691A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7537930B2 (en) | 2004-07-23 | 2009-05-26 | Immunomedics, Inc. | Mammalian cell lines for increasing longevity and protein yield from a cell culture |
| KR101794638B1 (ko) * | 2008-06-10 | 2017-12-04 | 상가모 테라퓨틱스, 인코포레이티드 | Ｂａｘ- 및 ｂａｋ-결함 세포주들의 제조 방법 및 조성물 |
| JP5665065B2 (ja) * | 2011-04-28 | 2015-02-04 | 国立大学法人大阪大学 | リソソーム病治療用医薬組成物 |
| US9365825B2 (en) * | 2013-03-11 | 2016-06-14 | Taiga Biotechnologies, Inc. | Expansion of adult stem cells in vitro |
| EP2970915B1 (en) * | 2013-03-15 | 2019-08-14 | Maxcyte, Inc. | Methods and compositions for generating stable transfected cells |
| KR20170135966A (ko) | 2015-04-13 | 2017-12-08 | 맥스시티 인코포레이티드 | 게놈 dna를 변형시키기 위한 방법 및 조성물 |
| GB201511196D0 (en) * | 2015-06-25 | 2015-08-12 | Cytosystems Ltd | Monoclonal antibodies |
| CN111808822B (zh) * | 2020-07-02 | 2024-01-12 | 北京百普赛斯生物科技股份有限公司 | 细胞培养用补料液及提高重组hek293细胞蛋白表达量的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0471484A (ja) * | 1990-07-11 | 1992-03-06 | Teijin Ltd | 低凝集性細胞及びその培養方法 |
| AU7614600A (en) * | 1999-09-27 | 2001-04-30 | Genentech Inc. | Methods for making recombinant proteins using apoptosis inhibitors |
| US7604989B2 (en) * | 2001-07-10 | 2009-10-20 | Johns Hopkins University | Inhibition of apoptosis process and improvement of cell performance |
| WO2003040374A1 (en) * | 2001-11-02 | 2003-05-15 | Centocor, Inc. | METHODS AND COMPOSITIONS FOR ENHANCED PROTEIN EXPRESSION AND/OR GROWTH OF CULTURED CELLS USING CO-TRANSCRIPTION OF A Bcl2 ENCODING NUCLEIC ACID |
| US6964199B2 (en) * | 2001-11-02 | 2005-11-15 | Cantocor, Inc. | Methods and compositions for enhanced protein expression and/or growth of cultured cells using co-transcription of a Bcl2 encoding nucleic acid |
| EP1490481A4 (en) * | 2001-12-14 | 2005-12-07 | Centocor Inc | CLONAL CELL LINES OF MYELOMES FOR PRODUCING PROTEINS IN A CHEMICALLY DEFINED ENVIRONMENT |
| US20030219871A1 (en) * | 2002-03-28 | 2003-11-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Host cells having improved cell survival properties and methods to generate such cells |
| US7537930B2 (en) * | 2004-07-23 | 2009-05-26 | Immunomedics, Inc. | Mammalian cell lines for increasing longevity and protein yield from a cell culture |
-
2005
- 2005-07-25 SG SG201004954-2A patent/SG163592A1/en unknown
- 2005-07-25 JP JP2007529867A patent/JP5378682B2/ja not_active Expired - Lifetime
- 2005-07-25 WO PCT/US2005/026224 patent/WO2007015691A2/en not_active Ceased
- 2005-07-25 CA CA2576464A patent/CA2576464C/en not_active Expired - Lifetime
- 2005-07-25 EP EP05857896.4A patent/EP1802646B1/en not_active Expired - Lifetime
-
2012
- 2012-07-24 JP JP2012163611A patent/JP2012254084A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2576464A1 (en) | 2006-01-23 |
| CA2576464C (en) | 2014-09-09 |
| EP1802646B1 (en) | 2017-09-06 |
| JP5378682B2 (ja) | 2013-12-25 |
| EP1802646A2 (en) | 2007-07-04 |
| EP1802646A4 (en) | 2009-10-21 |
| WO2007015691A3 (en) | 2009-04-02 |
| JP2008507300A (ja) | 2008-03-13 |
| WO2007015691A9 (en) | 2007-04-19 |
| JP2012254084A (ja) | 2012-12-27 |
| WO2007015691A2 (en) | 2007-02-08 |
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