JP2008505157A5 - - Google Patents

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Publication number
JP2008505157A5
JP2008505157A5 JP2007519725A JP2007519725A JP2008505157A5 JP 2008505157 A5 JP2008505157 A5 JP 2008505157A5 JP 2007519725 A JP2007519725 A JP 2007519725A JP 2007519725 A JP2007519725 A JP 2007519725A JP 2008505157 A5 JP2008505157 A5 JP 2008505157A5
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JP
Japan
Prior art keywords
compound
optionally substituted
optionally
alkyl
general formula
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JP2007519725A
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English (en)
Japanese (ja)
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JP2008505157A (ja
JP5142713B2 (ja
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Priority claimed from DE102004033670A external-priority patent/DE102004033670A1/de
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Publication of JP2008505157A publication Critical patent/JP2008505157A/ja
Publication of JP2008505157A5 publication Critical patent/JP2008505157A5/ja
Application granted granted Critical
Publication of JP5142713B2 publication Critical patent/JP5142713B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007519725A 2004-07-09 2005-07-07 新規ピリドジヒドロピラジノン、その製造方法及びその薬物としての使用 Expired - Lifetime JP5142713B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004033670.9 2004-07-09
DE102004033670A DE102004033670A1 (de) 2004-07-09 2004-07-09 Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
PCT/EP2005/007347 WO2006005510A1 (de) 2004-07-09 2005-07-07 Neue pyridodihydropyrazinone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
JP2008505157A JP2008505157A (ja) 2008-02-21
JP2008505157A5 true JP2008505157A5 (cg-RX-API-DMAC10.html) 2008-09-04
JP5142713B2 JP5142713B2 (ja) 2013-02-13

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ID=35033446

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007519725A Expired - Lifetime JP5142713B2 (ja) 2004-07-09 2005-07-07 新規ピリドジヒドロピラジノン、その製造方法及びその薬物としての使用

Country Status (6)

Country Link
US (2) US7625899B2 (cg-RX-API-DMAC10.html)
EP (1) EP1768981B1 (cg-RX-API-DMAC10.html)
JP (1) JP5142713B2 (cg-RX-API-DMAC10.html)
CA (1) CA2573092C (cg-RX-API-DMAC10.html)
DE (1) DE102004033670A1 (cg-RX-API-DMAC10.html)
WO (1) WO2006005510A1 (cg-RX-API-DMAC10.html)

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US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
EP2935261A1 (de) * 2012-12-20 2015-10-28 Bayer Pharma Aktiengesellschaft Bet-proteininhibitorische dihydrochinoxalinone
WO2015011084A1 (de) * 2013-07-23 2015-01-29 Bayer Pharma Aktiengesellschaft Substituierte dihydropyrido[3,4-b]pyrazinone als duale inhibitoren von bet-proteinen und polo-like kinasen
JP2016525532A (ja) 2013-07-26 2016-08-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 骨髄異形成症候群の処置
WO2015193229A1 (de) * 2014-06-19 2015-12-23 Bayer Pharma Aktiengesellschaft Bet-proteininhibitorische 1,4-dihydropyrido[3,4-b]pyrazinone mit meta-substituierter aromatischer amino- oder ethergruppe
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DE102017005091A1 (de) 2016-05-30 2017-11-30 Bayer Pharma Aktiengesellschaft Substituierte 3,4-Dihydropyrido[2,3-b]pyrazin-2(1H)-one
DE102017005089A1 (de) 2016-05-30 2017-11-30 Bayer Pharma Aktiengesellschaft Substitulerte 3,4-Dihydrochinoxalin-2(1H)-one

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US7728134B2 (en) * 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US20060074088A1 (en) * 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
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EP1632493A1 (de) * 2004-08-25 2006-03-08 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
JP2008510770A (ja) * 2004-08-26 2008-04-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｌｋ阻害剤としての新規プテリジノン
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JP2009529038A (ja) * 2006-03-07 2009-08-13 アストラゼネカ・アクチエボラーグ ピペリジン誘導体、それらの製造法、治療剤としてのそれらの使用およびそれらを含む医薬組成物
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