JP2008504335A5 - - Google Patents
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- Publication number
- JP2008504335A5 JP2008504335A5 JP2007518555A JP2007518555A JP2008504335A5 JP 2008504335 A5 JP2008504335 A5 JP 2008504335A5 JP 2007518555 A JP2007518555 A JP 2007518555A JP 2007518555 A JP2007518555 A JP 2007518555A JP 2008504335 A5 JP2008504335 A5 JP 2008504335A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- double
- building blocks
- molecule
- nucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58467804P | 2004-07-02 | 2004-07-02 | |
| US64658605P | 2005-01-26 | 2005-01-26 | |
| PCT/EP2005/007198 WO2006002971A2 (en) | 2004-07-02 | 2005-07-04 | Nucleic acids for the treatment of hmgb1-related pathologies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008504335A JP2008504335A (ja) | 2008-02-14 |
| JP2008504335A5 true JP2008504335A5 (https=) | 2008-08-21 |
Family
ID=35106975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007518555A Pending JP2008504335A (ja) | 2004-07-02 | 2005-07-04 | Ｈｍｇｂ１に関連する病変の治療のための核酸 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20080305073A1 (https=) |
| EP (1) | EP1768677B1 (https=) |
| JP (1) | JP2008504335A (https=) |
| AT (1) | ATE399014T1 (https=) |
| AU (1) | AU2005259381A1 (https=) |
| BR (1) | BRPI0512944A (https=) |
| CA (1) | CA2572519A1 (https=) |
| DE (1) | DE602005007746D1 (https=) |
| DK (1) | DK1768677T3 (https=) |
| ES (1) | ES2306195T3 (https=) |
| IL (1) | IL179828A0 (https=) |
| PL (1) | PL1768677T3 (https=) |
| PT (1) | PT1768677E (https=) |
| WO (1) | WO2006002971A2 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5188804B2 (ja) | 2004-08-03 | 2013-04-24 | トランステック ファーマ，インコーポレイティド | Ｒａｇｅ融合タンパク質及びその使用方法 |
| US20100172909A1 (en) * | 2005-10-24 | 2010-07-08 | Masahiro Nishibori | Cerebral edema suppressant |
| KR20080105066A (ko) * | 2006-02-09 | 2008-12-03 | 트랜스테크 파르마, 인크. | Ｒａｇｅ 융합 단백질 및 이의 사용 방법 |
| JP3882090B1 (ja) * | 2006-05-19 | 2007-02-14 | 国立大学法人 岡山大学 | 脳血管攣縮抑制剤 |
| CN101589309A (zh) * | 2006-11-17 | 2009-11-25 | 临床基因网络公司 | 涉及基因gypc、agpat3、agl、pvrl2、hmgb3、hsdl2和/或ldb2的筛选和治疗方法 |
| US20100056608A1 (en) * | 2006-11-17 | 2010-03-04 | Clinical Gene Networks Ab | Methods for screening and treatment involving the genes gypc, agpat3, agl, pvrl2, hmgb 3, hsdl2 and/or ldb2 |
| US8927510B2 (en) | 2008-05-16 | 2015-01-06 | Children's Medical Center Corporation | Compositions and methods for inhibition of retroviruses |
| WO2009149921A2 (en) * | 2008-06-11 | 2009-12-17 | Bionucleon S.R.L. | Inhibition of hrp-3 using modified oligonucleotides |
| DK2329266T3 (en) | 2008-09-11 | 2016-07-18 | Pasteur Institut | MONITORING AND INHIBITING INFECTION WITH HUMAN IMMUNE DEFECT VIRUS BY MODULATING HMGB1-DEPENDENT TRACTOR OF HIV-1 REPLICATION AND PERSISTENCE |
| US20120165244A1 (en) * | 2008-10-30 | 2012-06-28 | Hua-Lin Wu | Methods for binding lewis y antigen |
| PT2381964E (pt) | 2008-12-22 | 2014-08-29 | Creabilis S A | Síntese de conjugados poliméricos de compostos de indolocarbazol |
| US9034341B2 (en) | 2009-04-20 | 2015-05-19 | Transtech Pharma, Llc | Control of RAGE fusion protein glycosylation and RAGE fusion protein compositions |
| GB0911569D0 (en) * | 2009-07-03 | 2009-08-12 | Ulive Entpr Ltd | Method for the detection of organ or tissue injury |
| JP5467313B2 (ja) * | 2009-09-28 | 2014-04-09 | 国立大学法人 岡山大学 | アテローム動脈硬化抑制剤 |
| US8975019B2 (en) * | 2009-10-19 | 2015-03-10 | University Of Massachusetts | Deducing exon connectivity by RNA-templated DNA ligation/sequencing |
| WO2012036215A1 (ja) | 2010-09-17 | 2012-03-22 | Taniguchi Tadatsugu | Ｈｍｇｂタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法 |
| US20140378531A1 (en) * | 2012-02-01 | 2014-12-25 | New York University | Inhibition of pattern recognition receptors in pancreatic cancer treatment using tlr inhibitors |
| JP6624542B2 (ja) * | 2015-02-05 | 2019-12-25 | 国立大学法人広島大学 | ヒトｈｍｇｂ１結合剤およびヒトｈｍｇｂ１除去装置 |
| WO2018175340A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Reduced exposure conjugates modulating therapeutic targets |
| WO2018175315A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates of staurosporine derivatives having reduced exposure |
| WO2018175301A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugate of montesanib with reduced exposure |
| WO2018175302A1 (en) | 2017-03-20 | 2018-09-27 | Sienna Biopharmaceuticals, Inc. | Polymer conjugates targeting c-src with reduced exposure |
| EP3621657A1 (en) | 2017-05-10 | 2020-03-18 | Sienna Biopharmaceuticals, Inc. | Uses of polymer conjugates of indolocarbazole compounds with reduced exposure |
| CN111304202B (zh) * | 2020-02-26 | 2023-03-28 | 西安交通大学 | 一种用于识别且增强hmgb1生物学活性的核酸适配子及其应用 |
| CN114957440A (zh) * | 2022-05-26 | 2022-08-30 | 江苏大学 | 一种重组HMGB1 A Box蛋白及其获取方法与应用 |
| EP4543459A1 (en) * | 2022-06-23 | 2025-04-30 | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone | Hmgb1 inhibitors for treatment of apoe4-related tauopathies including alzheimer's disease |
| CN114807150B (zh) * | 2022-06-28 | 2022-10-14 | 中国科学院基础医学与肿瘤研究所(筹) | 靶向和拮抗hmgb1分子的核酸适体 |
| JP2025525583A (ja) | 2022-07-19 | 2025-08-05 | ランパート バイオサイエンス インコーポレイテッド | 非免疫原性環状非ウイルス性ｄｎａベクター |
| CN115774004B (zh) * | 2022-08-19 | 2024-07-05 | 四川大学华西医院 | 二氧化锆@量子点复合微球在制备检测hmgb1的荧光探针中的用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0672188B1 (en) * | 1992-10-14 | 2003-12-10 | NeXstar Pharmaceuticals, Inc. | Method for selecting nucleic acids on the basis of structure |
| US7754217B2 (en) * | 2001-03-16 | 2010-07-13 | Bio3 Research Srl | HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
| CA2506328A1 (en) * | 2002-11-20 | 2004-06-03 | Critical Therapeutics, Inc. | Use of hmgb fragments as anti-inflammatory agents |
-
2005
- 2005-07-04 PL PL05773148T patent/PL1768677T3/pl unknown
- 2005-07-04 PT PT05773148T patent/PT1768677E/pt unknown
- 2005-07-04 WO PCT/EP2005/007198 patent/WO2006002971A2/en not_active Ceased
- 2005-07-04 BR BRPI0512944-3A patent/BRPI0512944A/pt not_active IP Right Cessation
- 2005-07-04 EP EP05773148A patent/EP1768677B1/en not_active Revoked
- 2005-07-04 DK DK05773148T patent/DK1768677T3/da active
- 2005-07-04 CA CA002572519A patent/CA2572519A1/en not_active Abandoned
- 2005-07-04 AT AT05773148T patent/ATE399014T1/de not_active IP Right Cessation
- 2005-07-04 ES ES05773148T patent/ES2306195T3/es not_active Expired - Lifetime
- 2005-07-04 JP JP2007518555A patent/JP2008504335A/ja active Pending
- 2005-07-04 US US11/631,328 patent/US20080305073A1/en not_active Abandoned
- 2005-07-04 AU AU2005259381A patent/AU2005259381A1/en not_active Abandoned
- 2005-07-04 DE DE602005007746T patent/DE602005007746D1/de not_active Revoked
-
2006
- 2006-12-04 IL IL179828A patent/IL179828A0/en unknown
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