JP2008504300A - アレルギー性疾患を処置するための局所処方物 - Google Patents

アレルギー性疾患を処置するための局所処方物 Download PDF

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Publication number
JP2008504300A
JP2008504300A JP2007518371A JP2007518371A JP2008504300A JP 2008504300 A JP2008504300 A JP 2008504300A JP 2007518371 A JP2007518371 A JP 2007518371A JP 2007518371 A JP2007518371 A JP 2007518371A JP 2008504300 A JP2008504300 A JP 2008504300A
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JP
Japan
Prior art keywords
alkyl
formula
oxepin
mmol
allergic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007518371A
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English (en)
Japanese (ja)
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JP2008504300A5 (enExample
Inventor
マーク アール． ヘルバーグ，
Original Assignee
アルコン，インコーポレイテッド
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Application filed by アルコン，インコーポレイテッド filed Critical アルコン，インコーポレイテッド
Publication of JP2008504300A publication Critical patent/JP2008504300A/ja
Publication of JP2008504300A5 publication Critical patent/JP2008504300A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2007518371A 2004-06-28 2005-06-27 アレルギー性疾患を処置するための局所処方物 Withdrawn JP2008504300A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58338004P 2004-06-28 2004-06-28
PCT/US2005/022940 WO2006004757A2 (en) 2004-06-28 2005-06-27 Topical formulations for treating allergic diseases

Publications (2)

Publication Number Publication Date
JP2008504300A true JP2008504300A (ja) 2008-02-14
JP2008504300A5 JP2008504300A5 (enExample) 2008-07-17

Family

ID=35502431

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007518371A Withdrawn JP2008504300A (ja) 2004-06-28 2005-06-27 アレルギー性疾患を処置するための局所処方物

Country Status (11)

Country Link
US (1) US20050288283A1 (enExample)
EP (1) EP1761259A2 (enExample)
JP (1) JP2008504300A (enExample)
KR (1) KR20070024618A (enExample)
CN (1) CN1976694A (enExample)
AU (1) AU2005259911A1 (enExample)
BR (1) BRPI0512732A (enExample)
CA (1) CA2569519A1 (enExample)
MX (1) MXPA06014648A (enExample)
WO (1) WO2006004757A2 (enExample)
ZA (1) ZA200610350B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070001232A (ko) * 2004-04-21 2007-01-03 교와 핫꼬 고교 가부시끼가이샤 만성 부비강염의 예방 및/또는 치료제
US20060111436A1 (en) * 2004-11-23 2006-05-25 John Griffin Compositions and treatments for modulating kinase and/or HMG-CoA reductase
EP2067777B1 (en) * 2006-09-29 2013-08-14 Nippon Zoki Pharmaceutical Co., Ltd. Oxepin derivative
JP5564060B2 (ja) * 2009-02-05 2014-07-30 ザック システム エス．ピー．エー． オロパタジン及び／又はその薬学的に許容され得る塩の製造方法
CN104603775B (zh) * 2012-08-14 2018-06-19 华为技术有限公司 事务的回滚方法和装置，以及关系数据库管理系统
CN106117176B (zh) * 2016-06-24 2018-12-11 四川大学 二氢双苯并恶庚衍生物及其组合物与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923892A (en) * 1985-08-17 1990-05-08 Burroughs Wellcome Co. Tricyclic aromatic compounds
GB8520662D0 (en) * 1985-08-17 1985-09-25 Wellcome Found Tricyclic aromatic compounds
JPS6310784A (ja) * 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
US5641805A (en) * 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
JP2003534318A (ja) * 2000-05-19 2003-11-18 アルコン，インコーポレイテッド アレルギー性疾患を処置するために有用なジスルフィド誘導体
DK1284722T3 (da) * 2000-05-19 2005-09-19 Alcon Inc Sammensætninger indeholdende et benzamiddisulfidderivat til behandling af allergiske sygdomme
DE60104690T2 (de) * 2000-05-19 2005-01-13 Alcon, Inc. Anilin-disulfid-derivate zur behandlung allergischer erkrankungen
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration

Also Published As

Publication number Publication date
WO2006004757A3 (en) 2006-03-09
ZA200610350B (en) 2008-12-31
BRPI0512732A (pt) 2008-04-08
AU2005259911A1 (en) 2006-01-12
CN1976694A (zh) 2007-06-06
EP1761259A2 (en) 2007-03-14
MXPA06014648A (es) 2007-02-12
CA2569519A1 (en) 2006-01-12
KR20070024618A (ko) 2007-03-02
US20050288283A1 (en) 2005-12-29
WO2006004757A2 (en) 2006-01-12

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