|
KR100509388B1
(ko)
|
1996-10-18 |
2005-08-23 |
버텍스 파마슈티칼스 인코포레이티드 |
세린 프로테아제, 특히 간염 ｃ 바이러스 ｎｓ３ 프로테아제의 저해제
|
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
|
US7176208B2
(en)
|
2003-04-18 |
2007-02-13 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors
|
|
CL2004001161A1
(es)
*
|
2003-05-21 |
2005-04-08 |
Boehringer Ingelheim Int |
Compuestos describe compuestos derivados de quinolina; composicion farmaceutica; y su uso para tratar una enfermedad causada por el virus de la hepatitis c.
|
|
JP4914355B2
(ja)
*
|
2004-07-20 |
2012-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｃ型肝炎インヒビターペプチド類似体
|
|
UY29016A1
(es)
*
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
TWI389908B
(zh)
*
|
2005-07-14 |
2013-03-21 |
Gilead Sciences Inc |
抗病毒化合物類
|
|
JP2009501732A
(ja)
*
|
2005-07-20 |
2009-01-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｃ型肝炎インヒビターペプチド類似体
|
|
MX2008001166A
(es)
|
2005-07-25 |
2008-03-18 |
Intermune Inc |
Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis c.
|
|
US8076365B2
(en)
|
2005-08-12 |
2011-12-13 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7816348B2
(en)
|
2006-02-03 |
2010-10-19 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
|
EP2049474B1
(en)
|
2006-07-11 |
2015-11-04 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
EP1886685A1
(en)
|
2006-08-11 |
2008-02-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
|
|
JP2010500978A
(ja)
|
2006-08-17 |
2010-01-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ウイルスポリメラーゼインヒビター
|
|
CN101583372A
(zh)
*
|
2006-10-24 |
2009-11-18 |
默克公司 |
Hcv ns3蛋白酶抑制剂
|
|
US8343477B2
(en)
|
2006-11-01 |
2013-01-01 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
|
US7772180B2
(en)
*
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8003604B2
(en)
|
2006-11-16 |
2011-08-23 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7888464B2
(en)
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7763584B2
(en)
|
2006-11-16 |
2010-07-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP2125870A4
(en)
*
|
2007-02-16 |
2011-04-06 |
Boehringer Ingelheim Int |
INHIBITORS OF HEPATITIS C NS3 PROTEASE
|
|
CA2693997C
(en)
|
2007-08-03 |
2013-01-15 |
Pierre L. Beaulieu |
Viral polymerase inhibitors
|
|
MX2010006210A
(es)
|
2007-12-05 |
2010-08-10 |
Enanta Pharm Inc |
Inhibidores de serina proteasa de hcv de tripeptido fluorado.
|
|
CN101903351B
(zh)
|
2007-12-19 |
2014-09-10 |
贝林格尔.英格海姆国际有限公司 |
病毒聚合酶抑制剂
|
|
CA2710144A1
(en)
|
2007-12-21 |
2009-07-02 |
Avila Therapeutics, Inc. |
Hcv protease inhibitors and uses thereof
|
|
MX2010006736A
(es)
|
2007-12-21 |
2010-10-15 |
Avila Therapeutics Inc |
Inhibidores de proteasa del virus de la hepatitis c (hcv) y usos de los mismos.
|
|
US8202996B2
(en)
|
2007-12-21 |
2012-06-19 |
Bristol-Myers Squibb Company |
Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
|
|
US8293705B2
(en)
|
2007-12-21 |
2012-10-23 |
Avila Therapeutics, Inc. |
HCV protease inhibitors and uses thereof
|
|
US8309685B2
(en)
|
2007-12-21 |
2012-11-13 |
Celgene Avilomics Research, Inc. |
HCV protease inhibitors and uses thereof
|
|
RU2490272C2
(ru)
|
2008-02-04 |
2013-08-20 |
Айденикс Фармасьютикалз, Инк. |
Макроциклические ингибиторы серинпротеазы
|
|
US8163921B2
(en)
|
2008-04-16 |
2012-04-24 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US20090285774A1
(en)
*
|
2008-05-15 |
2009-11-19 |
Bristol-Myers Squibb Company |
Hepatitis C Virus Inhibitors
|
|
US7964560B2
(en)
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2009148923A1
(en)
|
2008-05-29 |
2009-12-10 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
TW201004632A
(en)
|
2008-07-02 |
2010-02-01 |
Idenix Pharmaceuticals Inc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US8207341B2
(en)
|
2008-09-04 |
2012-06-26 |
Bristol-Myers Squibb Company |
Process or synthesizing substituted isoquinolines
|
|
UY32099A
(es)
|
2008-09-11 |
2010-04-30 |
Enanta Pharm Inc |
Inhibidores macrocíclicos de serina proteasas de hepatitis c
|
|
CA2737958A1
(en)
*
|
2008-09-23 |
2010-04-01 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor compounds
|
|
US8044087B2
(en)
|
2008-09-29 |
2011-10-25 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8563505B2
(en)
|
2008-09-29 |
2013-10-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP2358736A1
(en)
*
|
2008-10-15 |
2011-08-24 |
Intermune, Inc. |
Therapeutic antiviral peptides
|
|
US8283310B2
(en)
|
2008-12-15 |
2012-10-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
JP2012514605A
(ja)
|
2009-01-07 |
2012-06-28 |
サイネクシス，インコーポレーテッド |
Ｈｃｖおよびｈｉｖ感染の治療への使用におけるシクロスポリン誘導体
|
|
JP5690286B2
(ja)
|
2009-03-04 |
2015-03-25 |
イデニク プハルマセウティカルス，インコーポレイテッド |
ホスホチオフェン及びホスホチアゾールｈｃｖポリメラーゼ阻害剤
|
|
WO2010118078A1
(en)
|
2009-04-08 |
2010-10-14 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors
|
|
EP2429568B1
(en)
|
2009-05-13 |
2016-08-17 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic compounds as hepatitis c virus inhibitors
|
|
US8232246B2
(en)
*
|
2009-06-30 |
2012-07-31 |
Abbott Laboratories |
Anti-viral compounds
|
|
TW201117812A
(en)
|
2009-08-05 |
2011-06-01 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
TW201116540A
(en)
*
|
2009-10-01 |
2011-05-16 |
Intermune Inc |
Therapeutic antiviral peptides
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
MX2012006877A
(es)
|
2009-12-18 |
2012-08-31 |
Idenix Pharmaceuticals Inc |
Inhibidores de virus de hepatitis c de arileno o heteroarileno 5, 5 - fusionado.
|
|
EP2552203B1
(en)
|
2010-04-01 |
2017-03-22 |
Idenix Pharmaceuticals LLC. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
JP5857053B2
(ja)
|
2010-09-21 |
2016-02-10 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
大環式プロリン由来ｈｃｖセリンプロテアーゼ阻害剤
|
|
CA2822556A1
(en)
|
2010-12-30 |
2012-07-05 |
Enanta Pharmaceuticals, Inc |
Macrocyclic hepatitis c serine protease inhibitors
|
|
EA201390988A1
(ru)
|
2010-12-30 |
2014-04-30 |
Энанта Фармасьютикалз, Инк. |
Фенантридиновые макроциклические ингибиторы сериновой протеазы вируса гепатита c
|
|
US9353100B2
(en)
|
2011-02-10 |
2016-05-31 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
|
|
WO2012107589A1
(en)
|
2011-02-11 |
2012-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
|
|
US9243025B2
(en)
|
2011-03-31 |
2016-01-26 |
Idenix Pharmaceuticals, Llc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
US8957203B2
(en)
|
2011-05-05 |
2015-02-17 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US10201584B1
(en)
|
2011-05-17 |
2019-02-12 |
Abbvie Inc. |
Compositions and methods for treating HCV
|
|
US8691757B2
(en)
|
2011-06-15 |
2014-04-08 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
AR088441A1
(es)
|
2011-09-12 |
2014-06-11 |
Idenix Pharmaceuticals Inc |
Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
CA2847892A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US8507460B2
(en)
|
2011-10-14 |
2013-08-13 |
Idenix Pharmaceuticals, Inc. |
Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
|
ES3018133T3
(en)
|
2011-11-30 |
2025-05-14 |
Univ Emory |
Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae
|
|
US20130217644A1
(en)
|
2012-02-13 |
2013-08-22 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical Compositions of 2'-C-Methyl-Guanosine, 5'-[2[(3-Hydroxy-2,2-Dimethyl-1-Oxopropyl)Thio]Ethyl N-(Phenylmethyl)Phosphoramidate]
|
|
US9296778B2
(en)
|
2012-05-22 |
2016-03-29 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphate prodrugs for HCV infection
|
|
WO2013177188A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
|
JP6165848B2
(ja)
|
2012-05-22 |
2017-07-19 |
イデニク ファーマシューティカルズ エルエルシー |
肝疾患のためのｄ−アミノ酸化合物
|
|
EP2906579B1
(en)
|
2012-10-08 |
2018-04-18 |
Idenix Pharmaceuticals LLC. |
2'-chloro nucleoside analogs for hcv infection
|
|
EP2909223B1
(en)
|
2012-10-19 |
2017-03-22 |
Idenix Pharmaceuticals LLC |
Dinucleotide compounds for hcv infection
|
|
EA025560B1
(ru)
|
2012-10-19 |
2017-01-30 |
Бристол-Майерс Сквибб Компани |
Ингибиторы вируса гепатита с
|
|
US10723754B2
(en)
|
2012-10-22 |
2020-07-28 |
Idenix Pharmaceuticals Llc |
2′,4′-bridged nucleosides for HCV infection
|
|
EP2914613B1
(en)
|
2012-11-02 |
2017-11-22 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
US9643999B2
(en)
|
2012-11-02 |
2017-05-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US9334279B2
(en)
|
2012-11-02 |
2016-05-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US9409943B2
(en)
|
2012-11-05 |
2016-08-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP2938624A1
(en)
|
2012-11-14 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
|
US20140140951A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-Alanine Ester of Rp-Nucleoside Analog
|
|
EP2935304A1
(en)
|
2012-12-19 |
2015-10-28 |
IDENIX Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
|
WO2014137926A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
3'-deoxy nucleosides for the treatment of hcv
|
|
WO2014137930A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
Thiophosphate nucleosides for the treatment of hcv
|
|
JP6342922B2
(ja)
|
2013-03-07 |
2018-06-13 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
Ｃ型肝炎ウイルス阻害剤
|
|
EP2981542B1
(en)
|
2013-04-01 |
2021-09-15 |
Idenix Pharmaceuticals LLC |
2',4'-fluoro nucleosides for the treatment of hcv
|
|
US10005779B2
(en)
|
2013-06-05 |
2018-06-26 |
Idenix Pharmaceuticals Llc |
1′,4′-thio nucleosides for the treatment of HCV
|
|
WO2015017713A1
(en)
|
2013-08-01 |
2015-02-05 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
|
US20160271162A1
(en)
|
2013-11-01 |
2016-09-22 |
Idenix Pharmacueticals, Llc |
D-alanine phosphoramide pronucleotides of 2'-methyl 2'-fluro guanosine nucleoside compounds for the treatment of hcv
|
|
EP3074399A1
(en)
|
2013-11-27 |
2016-10-05 |
Idenix Pharmaceuticals LLC |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
|
US10683321B2
(en)
|
2013-12-18 |
2020-06-16 |
Idenix Pharmaceuticals Llc |
4′-or nucleosides for the treatment of HCV
|
|
WO2015103490A1
(en)
|
2014-01-03 |
2015-07-09 |
Abbvie, Inc. |
Solid antiviral dosage forms
|
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
US20170066795A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid prodrug forms of 2'-chloro-2'-methyl uridine for hcv
|
|
WO2015134561A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
US10202411B2
(en)
|
2014-04-16 |
2019-02-12 |
Idenix Pharmaceuticals Llc |
3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV
|
|
EP3413915A1
(en)
|
2016-02-08 |
2018-12-19 |
Synaffix B.V. |
Antibody-conjugates with improved therapeutic index for targeting her2 tumours and method for improving therapeutic index of antibody-conjugates
|
|
EP3413920A1
(en)
|
2016-02-08 |
2018-12-19 |
Synaffix B.V. |
Bioconjugates containing sulfamide linkers for use in treatment
|
|
US10874746B2
(en)
|
2016-02-08 |
2020-12-29 |
Synaffix B.V. |
Sulfamide linkers for use in bioconjugates
|
|
WO2018026877A1
(en)
|
2016-08-05 |
2018-02-08 |
Calitor Sciences, Llc |
Process for preparing substituted quinolin-4-ol compounds
|