JP2008503475A - メマンチンの放出が改変された製剤 - Google Patents
メマンチンの放出が改変された製剤 Download PDFInfo
- Publication number
- JP2008503475A JP2008503475A JP2007516725A JP2007516725A JP2008503475A JP 2008503475 A JP2008503475 A JP 2008503475A JP 2007516725 A JP2007516725 A JP 2007516725A JP 2007516725 A JP2007516725 A JP 2007516725A JP 2008503475 A JP2008503475 A JP 2008503475A
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- JP
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- Prior art keywords
- dosage form
- oral dosage
- solid
- release
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58124204P | 2004-06-17 | 2004-06-17 | |
| PCT/US2005/021260 WO2006009769A1 (en) | 2004-06-17 | 2005-06-16 | Modified release formulation of memantine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008503475A true JP2008503475A (ja) | 2008-02-07 |
| JP2008503475A5 JP2008503475A5 (enExample) | 2011-02-24 |
Family
ID=34972465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516725A Pending JP2008503475A (ja) | 2004-06-17 | 2005-06-16 | メマンチンの放出が改変された製剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (9) | US8039009B2 (enExample) |
| EP (1) | EP1781261A1 (enExample) |
| JP (1) | JP2008503475A (enExample) |
| CN (1) | CN1968684A (enExample) |
| AU (1) | AU2005265031A1 (enExample) |
| BR (1) | BRPI0512177A (enExample) |
| CA (1) | CA2569015A1 (enExample) |
| EA (1) | EA011446B1 (enExample) |
| IL (1) | IL179991A0 (enExample) |
| MX (1) | MXPA06014587A (enExample) |
| WO (1) | WO2006009769A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017178963A (ja) * | 2013-07-30 | 2017-10-05 | ギリアード コネチカット, インコーポレイテッド | Sky阻害剤の製剤 |
| JPWO2016121664A1 (ja) * | 2015-01-26 | 2017-11-02 | 第一三共株式会社 | ピロールカルボキサミドの固形組成物 |
| JP2023551249A (ja) * | 2020-11-24 | 2023-12-07 | セントロ デ ネウロシエンシアス デ キューバ、セネウロ | アルツハイマー病の治療のためのマルチターゲット治療薬としてのナフタレン誘導体の医薬組成物 |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040122090A1 (en) * | 2001-12-07 | 2004-06-24 | Lipton Stuart A. | Methods for treating neuropsychiatric disorders with nmda receptor antagonists |
| US20060002999A1 (en) | 2004-06-17 | 2006-01-05 | Forest Laboratories, Inc. | Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane |
| TW200616608A (en) * | 2004-07-09 | 2006-06-01 | Forest Laboratories | Memantine as adjunctive treatment to atypical antipsychotics in schizophrenia patients |
| US7619007B2 (en) * | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
| US8058291B2 (en) | 2005-04-06 | 2011-11-15 | Adamas Pharmaceuticals, Inc. | Methods and compositions for the treatment of CNS-related conditions |
| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| EA013474B1 (ru) * | 2005-06-16 | 2010-04-30 | Форест Лэборэтериз, Инк. | Композиция в виде гранул с модифицированным и немедленным высвобождением мемантина |
| US20070077310A1 (en) * | 2005-10-03 | 2007-04-05 | University Of Tennessee Research Foundation | Methods of reducing the production of reactive oxygen species and methods of screening or identifying compounds and compositions that reduce the production of reactive oxygen species |
| US20070141148A1 (en) * | 2005-11-30 | 2007-06-21 | Merz Pharma Gmbh & Co. Kgaa | Neramexane MR matrix tablet |
| EP2040676A2 (en) * | 2006-07-06 | 2009-04-01 | Forest Laboratories, Inc. | Orally dissolving formulations of memantine |
| GB0623897D0 (en) * | 2006-11-30 | 2007-01-10 | Pliva Istrazivanje I Razvoj D | Pharmaceutical composition of memantine |
| US20080182908A1 (en) * | 2007-01-25 | 2008-07-31 | Vinita Umashankar Vyas | Pharmaceutical compositions comprising memantine |
| AU2008227465B2 (en) | 2007-03-22 | 2014-02-06 | Magceutics, Inc. | Magnesium compositions and uses thereof |
| TW200916091A (en) * | 2007-06-08 | 2009-04-16 | Merz Pharma Gmbh & Amp Co Kgaa | Neramexane for the treatment of nystagmus |
| EP2170310A4 (en) * | 2007-06-29 | 2010-06-23 | Orchid Chemicals & Pharm Ltd | FAST-DISSOLVING COMPOSITIONS OF MEMANTINE HYDROCHLORIDE |
| EP2583669A1 (en) | 2007-10-10 | 2013-04-24 | Rubicon Research Private Limited | Taste-masked orally disintegrating tablets of memantine hydrochloride |
| TWI478712B (zh) | 2008-09-30 | 2015-04-01 | Astellas Pharma Inc | 釋控性醫藥組成物 |
| WO2010112221A1 (en) | 2009-04-03 | 2010-10-07 | Synthon B.V. | Pharmaceutical compositions comprising memantine |
| KR20120100964A (ko) | 2009-09-30 | 2012-09-12 | 바이타패스 제네틱스 인코포레이티드 | 개인용 보조인자 및 사용 방법 |
| JP5885668B2 (ja) * | 2009-12-02 | 2016-03-15 | アダマス ファーマシューティカルズ, インコーポレイテッド | アマンタジン組成物および使用方法 |
| MX2013004123A (es) | 2010-10-12 | 2013-12-16 | Univ Johns Hopkins | Composiciones antitusigenas que comprenden memantina. |
| US20140004189A1 (en) * | 2011-01-25 | 2014-01-02 | Cadila Healthcare Limited | Modified release pharmaceutical compositions memantine |
| TR201104108A2 (tr) | 2011-04-27 | 2011-08-22 | Ali̇ Rai̇f İlaç Sanayi̇ A.Ş. | Uzatılmış salımlı memantin tablet. |
| MX2014000419A (es) | 2011-07-15 | 2014-09-22 | Nusirt Sciences Inc | Composicones y metodos para modular trayectorias metabolicas. |
| US9198454B2 (en) | 2012-03-08 | 2015-12-01 | Nusirt Sciences, Inc. | Compositions, methods, and kits for regulating energy metabolism |
| RU2488388C1 (ru) * | 2012-05-24 | 2013-07-27 | Ооо "Валента Интеллект" | Фармацевтическая композиция для профилактики и лечения психических, поведенческих, когнитивных расстройств |
| CN103417483B (zh) * | 2012-05-25 | 2017-09-12 | 杭州赛利药物研究所有限公司 | 盐酸美金刚缓释干混悬剂及其制备方法 |
| WO2014015047A1 (en) | 2012-07-17 | 2014-01-23 | The General Hospital Corporation | Compositions and methods to treat neurodegenerative diseases |
| ES2623176T3 (es) | 2012-08-16 | 2017-07-10 | Teva Pharmaceutical Industries Ltd. | Composición farmacéutica de memantina |
| RU2559776C2 (ru) * | 2012-08-20 | 2015-08-10 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | Фармацевтические композиции для лечения цереброваскулярных расстройств и способы их изготовления |
| UA107653U (uk) | 2012-10-01 | 2016-06-24 | Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" | Композиція лікарських засобів для лікування та профілактики поведінкових, психічних та когнітивних розладів |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63290818A (ja) * | 1987-03-11 | 1988-11-28 | レツク・トバルナ・フアルマセブトスキー・イン・ケミクニー・イジエルコブ・エヌ・ソル・オー | 高分子量ヒドロキシプロピルメチルセルロースを基剤にした徐放性錠剤 |
| JP2004515477A (ja) * | 2000-12-07 | 2004-05-27 | ニューロモレキュラー インコーポレイテッド | Nmdaレセプターアンタゴニストを用いて神経精神医学的障害を処置するための方法 |
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2005
- 2005-06-16 WO PCT/US2005/021260 patent/WO2006009769A1/en not_active Ceased
- 2005-06-16 US US11/155,330 patent/US8039009B2/en active Active
- 2005-06-16 JP JP2007516725A patent/JP2008503475A/ja active Pending
- 2005-06-16 BR BRPI0512177-9A patent/BRPI0512177A/pt not_active IP Right Cessation
- 2005-06-16 MX MXPA06014587A patent/MXPA06014587A/es not_active Application Discontinuation
- 2005-06-16 AU AU2005265031A patent/AU2005265031A1/en not_active Abandoned
- 2005-06-16 CN CNA200580019805XA patent/CN1968684A/zh active Pending
- 2005-06-16 EP EP05760426A patent/EP1781261A1/en not_active Withdrawn
- 2005-06-16 EA EA200700049A patent/EA011446B1/ru not_active IP Right Cessation
- 2005-06-16 CA CA002569015A patent/CA2569015A1/en not_active Abandoned
-
2006
- 2006-12-11 IL IL179991A patent/IL179991A0/en unknown
-
2011
- 2011-09-15 US US13/233,381 patent/US20120004318A1/en not_active Abandoned
-
2012
- 2012-09-14 US US13/618,014 patent/US20130012593A1/en not_active Abandoned
-
2013
- 2013-07-23 US US13/948,438 patent/US20130310460A1/en not_active Abandoned
-
2014
- 2014-03-28 US US14/228,944 patent/US20140213659A1/en not_active Abandoned
-
2015
- 2015-01-28 US US14/607,526 patent/US20150148427A1/en not_active Abandoned
- 2015-05-27 US US14/722,538 patent/US20150258031A1/en not_active Abandoned
-
2016
- 2016-07-20 US US15/215,456 patent/US10660868B2/en not_active Expired - Lifetime
-
2020
- 2020-04-17 US US16/852,158 patent/US20200268685A1/en not_active Abandoned
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| JPS63290818A (ja) * | 1987-03-11 | 1988-11-28 | レツク・トバルナ・フアルマセブトスキー・イン・ケミクニー・イジエルコブ・エヌ・ソル・オー | 高分子量ヒドロキシプロピルメチルセルロースを基剤にした徐放性錠剤 |
| JP2004515477A (ja) * | 2000-12-07 | 2004-05-27 | ニューロモレキュラー インコーポレイテッド | Nmdaレセプターアンタゴニストを用いて神経精神医学的障害を処置するための方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2017178963A (ja) * | 2013-07-30 | 2017-10-05 | ギリアード コネチカット, インコーポレイテッド | Sky阻害剤の製剤 |
| JPWO2016121664A1 (ja) * | 2015-01-26 | 2017-11-02 | 第一三共株式会社 | ピロールカルボキサミドの固形組成物 |
| JP2023551249A (ja) * | 2020-11-24 | 2023-12-07 | セントロ デ ネウロシエンシアス デ キューバ、セネウロ | アルツハイマー病の治療のためのマルチターゲット治療薬としてのナフタレン誘導体の医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006009769A1 (en) | 2006-01-26 |
| IL179991A0 (en) | 2007-05-15 |
| CN1968684A (zh) | 2007-05-23 |
| EA200700049A1 (ru) | 2007-04-27 |
| US20140213659A1 (en) | 2014-07-31 |
| US20130310460A1 (en) | 2013-11-21 |
| EP1781261A1 (en) | 2007-05-09 |
| US20200268685A1 (en) | 2020-08-27 |
| BRPI0512177A (pt) | 2008-02-12 |
| US8039009B2 (en) | 2011-10-18 |
| US20150148427A1 (en) | 2015-05-28 |
| US20060051416A1 (en) | 2006-03-09 |
| US20150258031A1 (en) | 2015-09-17 |
| CA2569015A1 (en) | 2006-01-26 |
| US20120004318A1 (en) | 2012-01-05 |
| US10660868B2 (en) | 2020-05-26 |
| US20160324803A1 (en) | 2016-11-10 |
| MXPA06014587A (es) | 2007-04-27 |
| AU2005265031A1 (en) | 2006-01-26 |
| EA011446B1 (ru) | 2009-02-27 |
| US20130012593A1 (en) | 2013-01-10 |
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