JP2008502323A - コブラ毒因子様機能を有するヒト補体c3誘導体 - Google Patents

コブラ毒因子様機能を有するヒト補体c3誘導体 Download PDF

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JP2008502323A
JP2008502323A JP2007511077A JP2007511077A JP2008502323A JP 2008502323 A JP2008502323 A JP 2008502323A JP 2007511077 A JP2007511077 A JP 2007511077A JP 2007511077 A JP2007511077 A JP 2007511077A JP 2008502323 A JP2008502323 A JP 2008502323A
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protein
modified
cvf
complement
human
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JP2008502323A5 (enExample
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カール−ウィルヘルム フォーゲル,
デイビッド シー. フリッジンガー,
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University of Hawaii at Hilo
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University of Hawaii at Hilo
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/472Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/463Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
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  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Transplantation (AREA)
JP2007511077A 2004-04-30 2005-04-29 コブラ毒因子様機能を有するヒト補体c3誘導体 Pending JP2008502323A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56706904P 2004-04-30 2004-04-30
US65324705P 2005-02-14 2005-02-14
US66735205P 2005-03-31 2005-03-31
PCT/US2005/015119 WO2005107785A2 (en) 2004-04-30 2005-04-29 Human complement c3 derivates with cobra venom factor-like function

Publications (2)

Publication Number Publication Date
JP2008502323A true JP2008502323A (ja) 2008-01-31
JP2008502323A5 JP2008502323A5 (enExample) 2008-05-29

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ID=35320733

Family Applications (1)

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JP2007511077A Pending JP2008502323A (ja) 2004-04-30 2005-04-29 コブラ毒因子様機能を有するヒト補体c3誘導体

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Country Link
US (2) US8632780B2 (enExample)
EP (1) EP1755658A4 (enExample)
JP (1) JP2008502323A (enExample)
KR (1) KR20070036057A (enExample)
AU (1) AU2005240096A1 (enExample)
CA (1) CA2565227A1 (enExample)
IL (1) IL178905A0 (enExample)
MX (1) MXPA06012321A (enExample)
WO (1) WO2005107785A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017519049A (ja) * 2014-06-12 2017-07-13 ユニヴァーシティ オブ ハワイUniversity Of Hawaii 免疫原性を低減するかまたは予防するためのヒト化コブラ毒因子の使用

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005003159A1 (en) 2003-07-03 2005-01-13 Koeln Johanna Complement depletion using recombinant human c3-derivatives
US8632780B2 (en) 2004-04-30 2014-01-21 University Of Hawaii Human complement C3 derivates with cobra venom factor-like function
WO2010056399A1 (en) * 2008-11-17 2010-05-20 Incode Biopharmaceutics, Inc. Method and composition for modulating the immune system and various inflammatory conditions comprising complement depletors
RU2549468C2 (ru) * 2013-08-09 2015-04-27 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт нормальной физиологии имени П.К. Анохина" Российской академии медицинских наук (ФГБУ "НИИНФ им. П.К. Анохина" РАМН") Способ определения стабилизации с3-конвертазы классического пути активации комплемента человека
US20190016766A1 (en) * 2015-10-07 2019-01-17 Daniel E. Benjamin Use of improved modulators of complement function as cancer therapeutics
US11903996B2 (en) * 2015-10-07 2024-02-20 David C. Fritzinger Modulators of complement function
CN106472354B (zh) * 2016-10-21 2019-05-31 新希望六和饲料股份有限公司 一种成年鸡用饲料盘
CN106472359B (zh) * 2016-10-21 2019-07-26 新希望六和饲料股份有限公司 一种1-3周龄雏鸡用饲料盘

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661347A (en) * 1982-11-12 1987-04-28 Scripps Clinic Cytotoxic compositions
CA2160127A1 (en) * 1993-04-07 1994-10-13 David C. Fritzinger Dna encoding cobra c3, cvf1, and cvf2
US5714344A (en) * 1993-04-07 1998-02-03 Georgetown University Protease-derivatized CVF
WO1996007738A2 (en) * 1994-09-08 1996-03-14 Imutran Limited Modified human c3 proteins
US6221657B1 (en) * 1995-09-08 2001-04-24 Imutran Limited Modified human C3 DNA sequences and vectors
US5922320A (en) * 1996-06-14 1999-07-13 Georgetown University Recombinant proCVF
WO2005003159A1 (en) * 2003-07-03 2005-01-13 Koeln Johanna Complement depletion using recombinant human c3-derivatives
US8632780B2 (en) * 2004-04-30 2014-01-21 University Of Hawaii Human complement C3 derivates with cobra venom factor-like function
US20100179092A1 (en) * 2006-11-15 2010-07-15 Fritzinger David C Human complement c3 derivatives with cobra venom factor-like function

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017519049A (ja) * 2014-06-12 2017-07-13 ユニヴァーシティ オブ ハワイUniversity Of Hawaii 免疫原性を低減するかまたは予防するためのヒト化コブラ毒因子の使用

Also Published As

Publication number Publication date
CA2565227A1 (en) 2005-11-17
US8632780B2 (en) 2014-01-21
US20080311132A1 (en) 2008-12-18
WO2005107785A3 (en) 2005-12-15
EP1755658A2 (en) 2007-02-28
WO2005107785A2 (en) 2005-11-17
MXPA06012321A (es) 2007-04-19
US20080234191A1 (en) 2008-09-25
IL178905A0 (en) 2007-03-08
AU2005240096A1 (en) 2005-11-17
EP1755658A4 (en) 2008-11-05
KR20070036057A (ko) 2007-04-02

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