JP2008500991A5 - - Google Patents
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- Publication number
- JP2008500991A5 JP2008500991A5 JP2007513846A JP2007513846A JP2008500991A5 JP 2008500991 A5 JP2008500991 A5 JP 2008500991A5 JP 2007513846 A JP2007513846 A JP 2007513846A JP 2007513846 A JP2007513846 A JP 2007513846A JP 2008500991 A5 JP2008500991 A5 JP 2008500991A5
- Authority
- JP
- Japan
- Prior art keywords
- bromo
- phenoxy
- carbonyl
- pyrazole
- acetic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0412198A GB0412198D0 (en) | 2004-05-29 | 2004-05-29 | Medicinal use of receptor ligands |
| GB0414196A GB0414196D0 (en) | 2004-06-24 | 2004-06-24 | Medicinal use of receptor ligands |
| GB0424018A GB0424018D0 (en) | 2004-10-29 | 2004-10-29 | Medicinal use of receptor ligands |
| PCT/EP2005/005884 WO2005115382A1 (en) | 2004-05-29 | 2005-05-30 | Crth2 receptor ligands for medicinal uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008500991A JP2008500991A (ja) | 2008-01-17 |
| JP2008500991A5 true JP2008500991A5 (OSRAM) | 2008-07-17 |
Family
ID=34993084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007513846A Ceased JP2008500991A (ja) | 2004-05-29 | 2005-05-30 | 医学的使用のためのｃｒｔｈ２レセプターリガンド |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8022063B2 (OSRAM) |
| EP (2) | EP1758579A1 (OSRAM) |
| JP (1) | JP2008500991A (OSRAM) |
| KR (1) | KR20070045153A (OSRAM) |
| AU (1) | AU2005247110B2 (OSRAM) |
| BR (1) | BRPI0511676A (OSRAM) |
| CA (1) | CA2568766A1 (OSRAM) |
| CR (1) | CR8838A (OSRAM) |
| EA (1) | EA014729B1 (OSRAM) |
| IL (1) | IL179694A (OSRAM) |
| MX (1) | MXPA06013912A (OSRAM) |
| NO (1) | NO20066048L (OSRAM) |
| NZ (1) | NZ551810A (OSRAM) |
| WO (1) | WO2005115382A1 (OSRAM) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| ATE517085T1 (de) * | 2004-11-23 | 2011-08-15 | Astrazeneca Ab | Zur behandlung von atemwegserkrankungen geeignete phenoxyessigsäurederivate |
| DK1928457T3 (da) * | 2005-09-30 | 2013-02-04 | Pulmagen Therapeutics Asthma Ltd | Quinoliner og deres terapeutiske anvendelse |
| WO2007039736A1 (en) | 2005-10-06 | 2007-04-12 | Astrazeneca Ab | Novel compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| WO2007062678A1 (en) * | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
| GB0524428D0 (en) * | 2005-11-30 | 2006-01-11 | 7Tm Pharma As | Medicinal use of receptor ligands |
| CL2007002593A1 (es) | 2006-09-07 | 2008-06-13 | Actelion Pharmaceuticals Ltd | Compuestos derivados de 4-heteroaril-piridina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como rechazo de organos transplantados, sindromes autoinmunes y cancer. |
| SI2069335T1 (sl) | 2006-09-08 | 2013-04-30 | Actelion Pharmaceuticals Ltd. | Derivati piridin-3-ila kot imunomodulacijska sredstva |
| EP2069318B1 (en) | 2006-09-21 | 2012-09-12 | Actelion Pharmaceuticals Ltd. | Phenyl derivatives and their use as immunomodulators |
| WO2008049864A1 (en) * | 2006-10-25 | 2008-05-02 | Neurosearch A/S | Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
| CN102442941A (zh) | 2006-12-14 | 2012-05-09 | 安斯泰来制药有限公司 | 用作crth2拮抗剂和抗过敏剂的多环酸化合物 |
| JP2010521450A (ja) | 2007-03-16 | 2010-06-24 | アクテリオン ファーマシューティカルズ リミテッド | Ｓ１ｐ１／ｅｄｇ１受容体アゴニストとしてのアミノ−ピリジン誘導体 |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| PL2195311T3 (pl) | 2007-08-17 | 2011-08-31 | Actelion Pharmaceuticals Ltd | Pochodne pirydynowe jako modulatory receptora S1P1/EDG1 |
| EA201070422A1 (ru) | 2007-10-04 | 2010-12-30 | Мерк Сероно С.А. | Производные оксадиазола |
| KR20100083814A (ko) | 2007-10-04 | 2010-07-22 | 메르크 세로노 에스. 에이. | 옥사디아졸 디아릴 화합물 |
| CN101970430B (zh) | 2007-11-01 | 2013-05-08 | 埃科特莱茵药品有限公司 | 嘧啶衍生物 |
| NZ585888A (en) | 2007-12-14 | 2012-02-24 | Pulmagen Therapeutics Asthma Ltd | Indoles and their therapeutic use |
| WO2009082398A1 (en) * | 2007-12-21 | 2009-07-02 | University Of Notre Dame Du Lac | Antibacterial compounds and methods of using same |
| BRPI0910288A2 (pt) | 2008-03-07 | 2019-09-24 | Actelion Pharmaceuticals Ltd | composto de derivados de aminometil benzeno, composição farmacêutica que compreende esse composto e uso do mesmo. |
| CN102016577B (zh) | 2008-05-09 | 2015-06-17 | 希森美康株式会社 | 血液分析装置,血液分析方法及溶血剂 |
| JP5394488B2 (ja) * | 2008-07-15 | 2014-01-22 | エフ．ホフマン−ラ ロシュ アーゲー | アミノテトラヒドロインダゾロ酢酸 |
| EP2307382B1 (en) * | 2008-07-15 | 2011-12-21 | F. Hoffmann-La Roche AG | Aminotetrahydroindazoloacetic acids |
| JP2012501975A (ja) * | 2008-09-08 | 2012-01-26 | メルク カナダ インコーポレイテッド | ステアロイルコエンザイムＡδ−９デサチュラーゼの阻害剤としての芳香族複素環化合物 |
| CN102264704B (zh) | 2008-12-25 | 2014-06-04 | 大正制药株式会社 | 异喹啉衍生物 |
| WO2010092043A1 (en) | 2009-02-12 | 2010-08-19 | Merck Serono S.A. | Phenoxy acetic acid derivatives |
| KR101409131B1 (ko) | 2009-07-16 | 2014-06-17 | 액테리온 파마슈티칼 리미티드 | 피리딘-4-일 유도체 |
| US8674115B2 (en) * | 2009-12-23 | 2014-03-18 | Ironwood Pharmaceuticals, Inc. | CRTH2 modulators |
| PH12012502478A1 (en) | 2010-06-23 | 2014-10-17 | Taisho Pharmaceutical Co Ltd | Isoquinoline derivative |
| TW201201805A (en) | 2010-07-05 | 2012-01-16 | Actelion Pharmaceuticals Ltd | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| SG191742A1 (en) | 2011-01-19 | 2013-08-30 | Actelion Pharmaceuticals Ltd | 2-methoxy-pyridin-4-yl derivatives |
| RS58718B1 (sr) * | 2011-05-12 | 2019-06-28 | Proteostasis Therapeutics Inc | Regulatori proteostaze |
| ES2563232T3 (es) | 2011-07-29 | 2016-03-11 | Taisho Pharmaceutical Co., Ltd. | Compuesto de amidina o sal del mismo |
| KR20140113667A (ko) | 2011-12-16 | 2014-09-24 | 아토픽스 테라퓨릭스 리미티드 | 호산구성 식도염의 치료를 위한 ｃｒｔｈ2 길항제 및 양성자 펌프 저해제의 조합 |
| CN104011021B (zh) | 2011-12-21 | 2016-08-24 | 埃科特莱茵药品有限公司 | 杂环衍生物及其作为前列腺素d2受体调节剂的用途 |
| US9169270B2 (en) | 2012-07-05 | 2015-10-27 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators |
| TWI695831B (zh) | 2014-09-13 | 2020-06-11 | 香港商南北兄弟藥業投資有限公司 | Ｃｒｔｈ２拮抗劑化合物及其用途 |
| US10662164B2 (en) | 2014-09-25 | 2020-05-26 | University Of Notre Dame Du Lac | Non-beta lactam antibiotics |
| MY192358A (en) | 2015-05-20 | 2022-08-17 | Idorsia Pharmaceuticals Ltd | Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol |
| WO2018049404A1 (en) | 2016-09-12 | 2018-03-15 | University Of Notre Dame Du Lac | Compounds for the treatment of clostridium difficile infection |
| EP3666254B1 (en) | 2017-08-11 | 2024-12-04 | Amorepacific Corporation | Pharmaceutical composition containing (r)-n-[1-(3,5-difluoro-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide |
| SG11202001684PA (en) | 2017-10-06 | 2020-03-30 | Forma Therapeutics Inc | Inhibiting ubiquitin specific peptidase 30 |
| WO2019178129A1 (en) | 2018-03-13 | 2019-09-19 | Shire Human Genetic Therapies, Inc. | Substituted imidazopyridines as inhibitors of plasma kallikrein and uses thereof |
| KR102518632B1 (ko) | 2018-04-18 | 2023-04-06 | (주)아모레퍼시픽 | (r)-n-[1-(3,5-다이플루오로-4-메테인설폰일아미노-페닐)-에틸]-3-(2-프로필-6-트라이플루오로메틸-피리딘-3-일)-아크릴아마이드를 함유하는 약학 조성물 |
| ES2988920T3 (es) | 2018-05-17 | 2024-11-22 | Forma Therapeutics Inc | Compuestos bicíclicos fusionados útiles como inhibidores de la peptidasa 30 específica de ubiquitina |
| PL3860989T3 (pl) | 2018-10-05 | 2023-07-10 | Forma Therapeutics, Inc. | Sprzężone piroliny, które działają jako inhibitory proteazy 30 swoistej dla ubikwityny (usp30) |
| PT4031547T (pt) | 2019-09-18 | 2024-08-27 | Takeda Pharmaceuticals Co | Inibidores de calicreína plasmática e utilizações dos mesmos |
| US11370803B2 (en) | 2019-09-18 | 2022-06-28 | Takeda Pharmaceutical Company Limited | Heteroaryl plasma kallikrein inhibitors |
| JPWO2022138700A1 (OSRAM) * | 2020-12-23 | 2022-06-30 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2104932A1 (en) * | 1970-09-08 | 1972-04-28 | Ferlux | O-hydroxyphenyl pyrazoles - hypocholesterolemics anti inflammatories analgesics etc |
| US5712303A (en) | 1992-12-17 | 1998-01-27 | Pfizer Inc. | Pyrazoles and pyrazolopyrimidines having CRF antagonistic activity |
| WO1999015520A1 (en) | 1997-09-19 | 1999-04-01 | Ono Pharmaceutical Co., Ltd. | Fused or nonfused benzene compounds |
| US6291514B1 (en) * | 1998-02-09 | 2001-09-18 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors |
| US6376527B1 (en) * | 1998-05-05 | 2002-04-23 | Syntex (U.S.A.) Llc | Pyrazole derivatives-p38 map kinase inhibitors |
| IL139169A0 (en) * | 1998-05-05 | 2001-11-25 | Hoffmann La Roche | Pyrazole derivatives as p-38 map kinase inhibitors |
| US6316466B1 (en) * | 1998-05-05 | 2001-11-13 | Syntex (U.S.A.) Llc | Pyrazole derivatives P-38 MAP kinase inhibitors |
| US6608101B1 (en) * | 2000-06-20 | 2003-08-19 | Atherogenics, Inc. | 1, 3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders |
| JP2004513076A (ja) * | 2000-07-25 | 2004-04-30 | メルク エンド カムパニー インコーポレーテッド | 糖尿病治療で有用なｎ−置換インドール類 |
| PL370909A1 (en) * | 2001-12-18 | 2005-05-30 | F.Hoffmann-La Roche Ag | Cis-imidazolines as mdm2 inhibitors |
| SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| SE0200356D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| WO2003097598A1 (en) | 2002-05-16 | 2003-11-27 | Shionogi & Co., Ltd. | Compound exhibiting pgd 2 receptor antagonism |
| WO2003097042A1 (en) | 2002-05-16 | 2003-11-27 | Shionogi & Co., Ltd. | Pgd2 receptor antagonist |
| GB2388540A (en) | 2002-05-17 | 2003-11-19 | Bayer Ag | New use of Ramatroban |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| NZ538031A (en) * | 2002-08-29 | 2007-10-26 | Merck & Co Inc | Indoles having anti-diabetic activity |
| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| WO2007062678A1 (en) * | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
-
2005
- 2005-05-30 JP JP2007513846A patent/JP2008500991A/ja not_active Ceased
- 2005-05-30 AU AU2005247110A patent/AU2005247110B2/en not_active Ceased
- 2005-05-30 EP EP05770220A patent/EP1758579A1/en not_active Withdrawn
- 2005-05-30 US US11/597,873 patent/US8022063B2/en not_active Expired - Fee Related
- 2005-05-30 NZ NZ551810A patent/NZ551810A/en unknown
- 2005-05-30 KR KR1020067027504A patent/KR20070045153A/ko not_active Ceased
- 2005-05-30 CA CA002568766A patent/CA2568766A1/en not_active Abandoned
- 2005-05-30 EP EP10177122A patent/EP2336113A1/en not_active Withdrawn
- 2005-05-30 WO PCT/EP2005/005884 patent/WO2005115382A1/en not_active Ceased
- 2005-05-30 MX MXPA06013912A patent/MXPA06013912A/es not_active Application Discontinuation
- 2005-05-30 BR BRPI0511676-7A patent/BRPI0511676A/pt not_active IP Right Cessation
- 2005-05-30 EA EA200602290A patent/EA014729B1/ru not_active IP Right Cessation
-
2006
- 2006-11-29 IL IL179694A patent/IL179694A/en not_active IP Right Cessation
- 2006-12-22 CR CR8838A patent/CR8838A/es not_active Application Discontinuation
- 2006-12-28 NO NO20066048A patent/NO20066048L/no not_active Application Discontinuation
-
2011
- 2011-06-02 US US13/151,317 patent/US20110269763A1/en not_active Abandoned
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