JP2008261842A - 光線を放射及び検出するための装置 - Google Patents
光線を放射及び検出するための装置 Download PDFInfo
- Publication number
- JP2008261842A JP2008261842A JP2008037696A JP2008037696A JP2008261842A JP 2008261842 A JP2008261842 A JP 2008261842A JP 2008037696 A JP2008037696 A JP 2008037696A JP 2008037696 A JP2008037696 A JP 2008037696A JP 2008261842 A JP2008261842 A JP 2008261842A
- Authority
- JP
- Japan
- Prior art keywords
- light
- excitation
- reaction
- light source
- light guide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0235—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using means for replacing an element by another, for replacing a filter or a grating
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/30—Measuring the intensity of spectral lines directly on the spectrum itself
- G01J3/32—Investigating bands of a spectrum in sequence by a single detector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6471—Special filters, filter wheel
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6484—Optical fibres
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/062—LED's
- G01N2201/0627—Use of several LED's for spectral resolution
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07102771A EP1962084A1 (en) | 2007-02-21 | 2007-02-21 | Apparatus for emitting and detecting beams of light |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008261842A true JP2008261842A (ja) | 2008-10-30 |
| JP2008261842A5 JP2008261842A5 (https=) | 2011-03-17 |
Family
ID=38082647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008037696A Pending JP2008261842A (ja) | 2007-02-21 | 2008-02-19 | 光線を放射及び検出するための装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7947442B2 (https=) |
| EP (2) | EP1962084A1 (https=) |
| JP (1) | JP2008261842A (https=) |
| CN (1) | CN101251486A (https=) |
| AU (1) | AU2008200772A1 (https=) |
| CA (1) | CA2621877A1 (https=) |
| RU (1) | RU2008106636A (https=) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011016509A1 (ja) * | 2009-08-06 | 2011-02-10 | ユニバーサル・バイオ・リサーチ株式会社 | 光ファイバ測定装置およびその測定方法 |
| JP2015503108A (ja) * | 2011-12-22 | 2015-01-29 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 光学システムにおける光源寿命の延長 |
| JP2016526670A (ja) * | 2013-06-19 | 2016-09-05 | エリューム・ピーティーワイ・リミテッド | 蛍光標識を用いた分析装置 |
| JP2017227642A (ja) * | 2016-06-24 | 2017-12-28 | タイゲン バイオサイエンス コーポレイション | 多重チャンネル蛍光検出システムおよびそれを使用する方法 |
| JP2018506039A (ja) * | 2015-02-06 | 2018-03-01 | ライフ テクノロジーズ コーポレーション | 生体サンプルを評価するためのシステムおよび方法 |
| KR20220061504A (ko) * | 2020-11-06 | 2022-05-13 | (주)바이오젠텍 | 형광 다중 유전자 등온증폭기 |
| JP2023516354A (ja) * | 2020-12-30 | 2023-04-19 | 北京中科生儀科技有限公司 | Pcr検出器及びその方法 |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2525211B1 (en) | 2011-05-16 | 2018-01-03 | F. Hoffmann-La Roche AG | Instrument and method for detecting analytes |
| GB201209738D0 (en) * | 2012-05-31 | 2012-07-18 | Ge Healthcare Bio Sciences Ab | Methods and apparatus for measuring the concentration of a substance in a solution |
| US9556477B2 (en) | 2012-07-17 | 2017-01-31 | Universal Bio Research Co., Ltd. | Light measurement apparatus for reaction vessel and light measurement method |
| CA2879638A1 (en) * | 2012-08-10 | 2014-02-13 | Streck, Inc. | Real-time optical system for polymerase chain reaction |
| US10101274B2 (en) | 2012-12-05 | 2018-10-16 | Genepoc Inc. | Optical interrogation device |
| AU2013202788B2 (en) | 2013-03-14 | 2015-10-01 | Gen-Probe Incorporated | Indexing signal detection module |
| AU2015275317A1 (en) * | 2013-03-14 | 2016-01-21 | Gen-Probe Incorporated | Indexing signal detection module |
| US10006861B2 (en) * | 2013-06-28 | 2018-06-26 | Streck, Inc. | Devices for real-time polymerase chain reaction |
| KR102126032B1 (ko) * | 2013-07-31 | 2020-07-08 | 삼성전자주식회사 | 다채널 형광 검출 모듈 및 이를 포함하는 핵산 분석 시스템 |
| FI128285B (en) * | 2014-06-27 | 2020-02-28 | Metso Automation Oy | Multichannel optical measurement unit, multichannel optical detector unit and related measurement method |
| CN104614351A (zh) * | 2015-01-21 | 2015-05-13 | 南京中科神光科技有限公司 | 一种快速、多通道实时荧光定量检测装置 |
| CN106680250B (zh) * | 2015-11-10 | 2023-06-30 | 北京万泰生物药业股份有限公司 | 用于聚合酶链式反应的检测机构及聚合酶链式反应装置 |
| GB201603380D0 (en) * | 2016-02-26 | 2016-04-13 | Ge Healthcare Bio Sciences Ab | Apparatus and method for measuring the light absorbance of a substance in a solution |
| SE539770C2 (en) | 2016-06-10 | 2017-11-21 | Bomill Ab | A detector system comprising a plurality of light guides and a spectrometer comprising the detector system |
| CN107101945A (zh) * | 2017-05-26 | 2017-08-29 | 北京智云达科技股份有限公司 | 一种多通道多波长光谱检测装置 |
| WO2019023294A1 (en) * | 2017-07-26 | 2019-01-31 | Gen-Probe Incorporated | MODULES AND METHODS FOR OPTICAL SIGNAL DETECTION |
| CN107478629A (zh) * | 2017-09-04 | 2017-12-15 | 中国科学院苏州生物医学工程技术研究所 | 一种大面积数字pcr微滴荧光高通量检测装置和方法 |
| KR102890778B1 (ko) * | 2019-02-27 | 2025-11-25 | 주식회사 씨젠 | 광모듈 |
| KR102943394B1 (ko) | 2019-05-31 | 2026-03-24 | 주식회사 씨젠 | 광 검출 장치 및 방법 |
| US12546720B2 (en) | 2020-03-31 | 2026-02-10 | Seegene, Inc. | Optical signal detection device comprising sample holder divided into sample areas and light source units dedicated thereto |
| WO2023032256A1 (ja) * | 2021-09-03 | 2023-03-09 | ソニーセミコンダクタソリューションズ株式会社 | 分光感度測定装置及び分光感度測定方法 |
| EP4419893A4 (en) * | 2021-10-20 | 2025-08-06 | Bio Rad Laboratories Inc | FLUORESCENCE DETECTION SYSTEM |
| EP4650753A1 (de) | 2024-05-15 | 2025-11-19 | Gerbion GmbH & Co. KG | Vorrichtung zur lumineszenzdetektion für temperaturabhängige reaktionssysteme |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001255272A (ja) * | 2000-01-14 | 2001-09-21 | Becton Dickinson & Co | 核酸アッセイ用自動光学リーダ |
| JP2004147706A (ja) * | 2002-10-28 | 2004-05-27 | Matsushita Electric Works Ltd | 非侵襲型生体成分の定量装置及び定量方法 |
| JP2004537053A (ja) * | 2001-07-25 | 2004-12-09 | アプレラ コーポレイション | 電気泳動検出システムにおける時間遅延積分 |
| JP2006215026A (ja) * | 2005-02-03 | 2006-08-17 | Samsung Electronics Co Ltd | 多チャンネル蛍光測定用の光学系及びそれを採用した多チャンネル蛍光試料の分析装置 |
Family Cites Families (16)
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| US4477190A (en) * | 1981-07-20 | 1984-10-16 | American Hospital Supply Corporation | Multichannel spectrophotometer |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| ES8706823A1 (es) | 1985-03-28 | 1987-06-16 | Cetus Corp | Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra |
| CA1339653C (en) | 1986-02-25 | 1998-02-03 | Larry J. Johnson | Appartus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps |
| US5994056A (en) | 1991-05-02 | 1999-11-30 | Roche Molecular Systems, Inc. | Homogeneous methods for nucleic acid amplification and detection |
| DE4424961C2 (de) | 1993-07-15 | 2002-05-08 | Perkin Elmer Corp | Wählvorrichtung für ein photometrisches Instrument mit Lichtleitfasern zur Analyse von entfernt befindlichen Proben |
| US6326605B1 (en) * | 1998-02-20 | 2001-12-04 | Ljl Biosystems, Inc. | Broad range light detection system |
| US6369893B1 (en) * | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
| EP0953838A1 (en) * | 1998-05-01 | 1999-11-03 | F. Hoffmann-La Roche Ag | Apparatus for simultaneously monitoring reactions taking place in a plurality of reaction vessels |
| EP0953837A1 (en) | 1998-05-01 | 1999-11-03 | F. Hoffmann-La Roche Ag | Fluorescence light measuring device and an apparatus wherein such a device is used |
| DE10131687A1 (de) | 2001-06-29 | 2003-01-16 | Eppendorf Ag | Vorrichtung zur Durchführung von Nukleinsäure-Amplifikationsreaktionen bei gleichzeitiger Verfolgung der Bildung von Amplifikationsprodukten |
| US7280207B2 (en) * | 2001-07-25 | 2007-10-09 | Applera Corporation | Time-delay integration in a flow cytometry system |
| EP2775291B1 (en) | 2002-05-17 | 2016-01-13 | Life Technologies Corporation | Apparatus for differentiating multiple fluorescence signals by excitation wavelength |
| EP2752874A1 (en) * | 2004-06-07 | 2014-07-09 | Fluidigm Corporation | Method and apparatus for imaging a device under temperature control |
| US7791728B2 (en) * | 2005-08-11 | 2010-09-07 | Hewlett-Packard Development Company, L.P. | System for optically analyzing a substance with a selected single-wavelength |
| WO2007091230A1 (en) * | 2006-02-07 | 2007-08-16 | Stokes Bio Limited | A microfluidic analysis system |
-
2007
- 2007-02-21 EP EP07102771A patent/EP1962084A1/en not_active Ceased
-
2008
- 2008-02-18 AU AU2008200772A patent/AU2008200772A1/en not_active Abandoned
- 2008-02-19 US US12/033,711 patent/US7947442B2/en not_active Expired - Fee Related
- 2008-02-19 JP JP2008037696A patent/JP2008261842A/ja active Pending
- 2008-02-20 RU RU2008106636/14A patent/RU2008106636A/ru not_active Application Discontinuation
- 2008-02-20 EP EP08003078A patent/EP1962085A3/en not_active Ceased
- 2008-02-20 CN CNA2008100881579A patent/CN101251486A/zh active Pending
- 2008-02-20 CA CA002621877A patent/CA2621877A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001255272A (ja) * | 2000-01-14 | 2001-09-21 | Becton Dickinson & Co | 核酸アッセイ用自動光学リーダ |
| JP2004537053A (ja) * | 2001-07-25 | 2004-12-09 | アプレラ コーポレイション | 電気泳動検出システムにおける時間遅延積分 |
| JP2004147706A (ja) * | 2002-10-28 | 2004-05-27 | Matsushita Electric Works Ltd | 非侵襲型生体成分の定量装置及び定量方法 |
| JP2006215026A (ja) * | 2005-02-03 | 2006-08-17 | Samsung Electronics Co Ltd | 多チャンネル蛍光測定用の光学系及びそれを採用した多チャンネル蛍光試料の分析装置 |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011016509A1 (ja) * | 2009-08-06 | 2011-02-10 | ユニバーサル・バイオ・リサーチ株式会社 | 光ファイバ測定装置およびその測定方法 |
| JPWO2011016509A1 (ja) * | 2009-08-06 | 2013-01-10 | ユニバーサル・バイオ・リサーチ株式会社 | 光ファイバ測定装置およびその測定方法 |
| US8696992B2 (en) | 2009-08-06 | 2014-04-15 | Universal Bio Research Co., Ltd. | Optical fiber measurement device and measurement method using same |
| JP2015503108A (ja) * | 2011-12-22 | 2015-01-29 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 光学システムにおける光源寿命の延長 |
| US11442012B2 (en) | 2013-06-19 | 2022-09-13 | Ellume Limited | Assay device employing fluorescent labels |
| US10578556B2 (en) | 2013-06-19 | 2020-03-03 | Ellume Limited | Assay device employing fluorescent labels |
| JP2016526670A (ja) * | 2013-06-19 | 2016-09-05 | エリューム・ピーティーワイ・リミテッド | 蛍光標識を用いた分析装置 |
| JP2018506039A (ja) * | 2015-02-06 | 2018-03-01 | ライフ テクノロジーズ コーポレーション | 生体サンプルを評価するためのシステムおよび方法 |
| US11920191B2 (en) | 2015-02-06 | 2024-03-05 | Life Technologies Corporation | Systems and methods for assessing biological samples |
| JP2017227642A (ja) * | 2016-06-24 | 2017-12-28 | タイゲン バイオサイエンス コーポレイション | 多重チャンネル蛍光検出システムおよびそれを使用する方法 |
| KR20220061504A (ko) * | 2020-11-06 | 2022-05-13 | (주)바이오젠텍 | 형광 다중 유전자 등온증폭기 |
| KR102503418B1 (ko) * | 2020-11-06 | 2023-02-27 | (주)바이오젠텍 | 형광 다중 유전자 등온증폭기 |
| JP2023516354A (ja) * | 2020-12-30 | 2023-04-19 | 北京中科生儀科技有限公司 | Pcr検出器及びその方法 |
| JP7438580B2 (ja) | 2020-12-30 | 2024-02-27 | 北京中科生儀科技有限公司 | Pcr検出器及びその方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US7947442B2 (en) | 2011-05-24 |
| AU2008200772A1 (en) | 2008-09-04 |
| RU2008106636A (ru) | 2009-08-27 |
| EP1962084A1 (en) | 2008-08-27 |
| EP1962085A3 (en) | 2008-09-24 |
| EP1962085A2 (en) | 2008-08-27 |
| CN101251486A (zh) | 2008-08-27 |
| CA2621877A1 (en) | 2008-08-21 |
| US20090068747A1 (en) | 2009-03-12 |
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