CN101251486A - 用于发射和检测光束的装置 - Google Patents

用于发射和检测光束的装置 Download PDF

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Publication number
CN101251486A
CN101251486A CNA2008100881579A CN200810088157A CN101251486A CN 101251486 A CN101251486 A CN 101251486A CN A2008100881579 A CNA2008100881579 A CN A2008100881579A CN 200810088157 A CN200810088157 A CN 200810088157A CN 101251486 A CN101251486 A CN 101251486A
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CN
China
Prior art keywords
excitation
light
reaction
sample
emission
Prior art date
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Pending
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CNA2008100881579A
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English (en)
Chinese (zh)
Inventor
R·伊滕
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN101251486A publication Critical patent/CN101251486A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0235—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using means for replacing an element by another, for replacing a filter or a grating
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/30—Measuring the intensity of spectral lines directly on the spectrum itself
    • G01J3/32—Investigating bands of a spectrum in sequence by a single detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6471—Special filters, filter wheel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0627—Use of several LED's for spectral resolution

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  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNA2008100881579A 2007-02-21 2008-02-20 用于发射和检测光束的装置 Pending CN101251486A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07102771A EP1962084A1 (en) 2007-02-21 2007-02-21 Apparatus for emitting and detecting beams of light
EP07102771.8 2007-02-21

Publications (1)

Publication Number Publication Date
CN101251486A true CN101251486A (zh) 2008-08-27

Family

ID=38082647

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2008100881579A Pending CN101251486A (zh) 2007-02-21 2008-02-20 用于发射和检测光束的装置

Country Status (7)

Country Link
US (1) US7947442B2 (https=)
EP (2) EP1962084A1 (https=)
JP (1) JP2008261842A (https=)
CN (1) CN101251486A (https=)
AU (1) AU2008200772A1 (https=)
CA (1) CA2621877A1 (https=)
RU (1) RU2008106636A (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103998906A (zh) * 2011-12-22 2014-08-20 霍夫曼-拉罗奇有限公司 光学系统中的光源寿命的延长
CN104614351A (zh) * 2015-01-21 2015-05-13 南京中科神光科技有限公司 一种快速、多通道实时荧光定量检测装置
CN105008878A (zh) * 2012-12-05 2015-10-28 吉恩波克公司 光学探询器件
CN106680250A (zh) * 2015-11-10 2017-05-17 北京万泰生物药业股份有限公司 用于聚合酶链式反应的检测机构及聚合酶链式反应装置
CN107101945A (zh) * 2017-05-26 2017-08-29 北京智云达科技股份有限公司 一种多通道多波长光谱检测装置
CN107478629A (zh) * 2017-09-04 2017-12-15 中国科学院苏州生物医学工程技术研究所 一种大面积数字pcr微滴荧光高通量检测装置和方法

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US8696992B2 (en) 2009-08-06 2014-04-15 Universal Bio Research Co., Ltd. Optical fiber measurement device and measurement method using same
EP2525211B1 (en) 2011-05-16 2018-01-03 F. Hoffmann-La Roche AG Instrument and method for detecting analytes
GB201209738D0 (en) * 2012-05-31 2012-07-18 Ge Healthcare Bio Sciences Ab Methods and apparatus for measuring the concentration of a substance in a solution
US9556477B2 (en) 2012-07-17 2017-01-31 Universal Bio Research Co., Ltd. Light measurement apparatus for reaction vessel and light measurement method
CA2879638A1 (en) * 2012-08-10 2014-02-13 Streck, Inc. Real-time optical system for polymerase chain reaction
AU2013202788B2 (en) 2013-03-14 2015-10-01 Gen-Probe Incorporated Indexing signal detection module
AU2015275317A1 (en) * 2013-03-14 2016-01-21 Gen-Probe Incorporated Indexing signal detection module
KR102302410B1 (ko) 2013-06-19 2021-09-16 엘룸 리미티드 형광 표지를 사용하는 분석 장치
US10006861B2 (en) * 2013-06-28 2018-06-26 Streck, Inc. Devices for real-time polymerase chain reaction
KR102126032B1 (ko) * 2013-07-31 2020-07-08 삼성전자주식회사 다채널 형광 검출 모듈 및 이를 포함하는 핵산 분석 시스템
FI128285B (en) * 2014-06-27 2020-02-28 Metso Automation Oy Multichannel optical measurement unit, multichannel optical detector unit and related measurement method
KR102494654B1 (ko) 2015-02-06 2023-01-31 라이프 테크놀로지스 코포레이션 생물학적 시료 평가 시스템과 방법
GB201603380D0 (en) * 2016-02-26 2016-04-13 Ge Healthcare Bio Sciences Ab Apparatus and method for measuring the light absorbance of a substance in a solution
SE539770C2 (en) 2016-06-10 2017-11-21 Bomill Ab A detector system comprising a plurality of light guides and a spectrometer comprising the detector system
TWI586957B (zh) * 2016-06-24 2017-06-11 諾貝爾生物有限公司 多通道螢光檢測系統及其方法
WO2019023294A1 (en) * 2017-07-26 2019-01-31 Gen-Probe Incorporated MODULES AND METHODS FOR OPTICAL SIGNAL DETECTION
KR102890778B1 (ko) * 2019-02-27 2025-11-25 주식회사 씨젠 광모듈
KR102943394B1 (ko) 2019-05-31 2026-03-24 주식회사 씨젠 광 검출 장치 및 방법
US12546720B2 (en) 2020-03-31 2026-02-10 Seegene, Inc. Optical signal detection device comprising sample holder divided into sample areas and light source units dedicated thereto
KR102503418B1 (ko) * 2020-11-06 2023-02-27 (주)바이오젠텍 형광 다중 유전자 등온증폭기
CN113607937B (zh) * 2020-12-30 2022-07-12 北京中科生仪科技有限公司 一种pcr检测方法的数据处理方法
WO2023032256A1 (ja) * 2021-09-03 2023-03-09 ソニーセミコンダクタソリューションズ株式会社 分光感度測定装置及び分光感度測定方法
EP4419893A4 (en) * 2021-10-20 2025-08-06 Bio Rad Laboratories Inc FLUORESCENCE DETECTION SYSTEM
EP4650753A1 (de) 2024-05-15 2025-11-19 Gerbion GmbH & Co. KG Vorrichtung zur lumineszenzdetektion für temperaturabhängige reaktionssysteme

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Cited By (11)

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Publication number Priority date Publication date Assignee Title
CN103998906A (zh) * 2011-12-22 2014-08-20 霍夫曼-拉罗奇有限公司 光学系统中的光源寿命的延长
CN103998906B (zh) * 2011-12-22 2016-12-21 霍夫曼-拉罗奇有限公司 光学系统中的光源寿命的延长
CN105008878A (zh) * 2012-12-05 2015-10-28 吉恩波克公司 光学探询器件
US10101274B2 (en) 2012-12-05 2018-10-16 Genepoc Inc. Optical interrogation device
CN104614351A (zh) * 2015-01-21 2015-05-13 南京中科神光科技有限公司 一种快速、多通道实时荧光定量检测装置
CN106680250A (zh) * 2015-11-10 2017-05-17 北京万泰生物药业股份有限公司 用于聚合酶链式反应的检测机构及聚合酶链式反应装置
WO2017080358A1 (zh) * 2015-11-10 2017-05-18 北京万泰生物药业股份有限公司 用于聚合酶链式反应的检测机构及聚合酶链式反应装置
US10864521B2 (en) 2015-11-10 2020-12-15 Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. Detection mechanism for polymerase chain reaction and polymerase chain reaction device
CN106680250B (zh) * 2015-11-10 2023-06-30 北京万泰生物药业股份有限公司 用于聚合酶链式反应的检测机构及聚合酶链式反应装置
CN107101945A (zh) * 2017-05-26 2017-08-29 北京智云达科技股份有限公司 一种多通道多波长光谱检测装置
CN107478629A (zh) * 2017-09-04 2017-12-15 中国科学院苏州生物医学工程技术研究所 一种大面积数字pcr微滴荧光高通量检测装置和方法

Also Published As

Publication number Publication date
JP2008261842A (ja) 2008-10-30
US7947442B2 (en) 2011-05-24
AU2008200772A1 (en) 2008-09-04
RU2008106636A (ru) 2009-08-27
EP1962084A1 (en) 2008-08-27
EP1962085A3 (en) 2008-09-24
EP1962085A2 (en) 2008-08-27
CA2621877A1 (en) 2008-08-21
US20090068747A1 (en) 2009-03-12

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