JP2007532572A5 - - Google Patents
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- JP2007532572A5 JP2007532572A5 JP2007507539A JP2007507539A JP2007532572A5 JP 2007532572 A5 JP2007532572 A5 JP 2007532572A5 JP 2007507539 A JP2007507539 A JP 2007507539A JP 2007507539 A JP2007507539 A JP 2007507539A JP 2007532572 A5 JP2007532572 A5 JP 2007532572A5
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- Prior art keywords
- irm
- soluble
- polymer
- polymer complex
- poly
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- 229920000642 polymer Polymers 0.000 claims 12
- 125000002947 alkylene group Chemical group 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 229920001389 Poly(hydroxyalkylmethacrylamide) Polymers 0.000 claims 1
- 108010020346 Polyglutamic Acid Proteins 0.000 claims 1
- 108010039918 Polylysine Proteins 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- 150000001336 alkenes Chemical class 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 1
- 229920000370 gamma-poly(glutamate) polymer Polymers 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 claims 1
- 230000004962 physiological condition Effects 0.000 claims 1
- -1 poly (alkylene glycol Chemical compound 0.000 claims 1
- 229920000765 poly(2-oxazolines) Polymers 0.000 claims 1
- 229920001390 poly(hydroxyalkylmethacrylate) Polymers 0.000 claims 1
- 229920002401 polyacrylamide Polymers 0.000 claims 1
- 229920000656 polylysine Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Claims (6)
- アルキレンオキシド含有ポリマーに結合された1つ以上のIRM化合物を含む、可溶性IRM−ポリマー複合体。
- 前記可溶性IRM−ポリマー複合体の溶解度が、生理学的条件下で、水1ミリリットルあたり少なくとも1マイクログラムである、請求項1に記載の可溶性IRM−ポリマー複合体。
- 前記IRM−ポリマー複合体の分子量が1kDa〜500kDaである、請求項1又は2に記載の可溶性IRM−ポリマー複合体。
- 前記IRM−ポリマー複合体の分子量が20kDa〜200kDaである、請求項3に記載の可溶性IRM−ポリマー複合体。
- 1つ以上のIRM化合物が、アルキレンオキシド含有ポリマーに共有結合で結合されている、請求項1〜4のいずれか1項に記載の可溶性IRM−ポリマー複合体。
- 前記可溶性ポリマーが、ポリ(アルキレングリコール)、ポリ(オレフィンアルコール)、ポリビニルピロリドン、ポリ(ヒドロキシアルキルメタクリルアミド)、ポリ(ヒドロキシアルキルメタクリレート)、ポリビニルアルコール、ポリオキサゾリン、ポリ(アクリル酸)、ポリアクリルアミド、ポリグルタメート、ポリリシン、多糖類、及びこれらの組み合わせからなる群から選択される、請求項1又は請求項1に従属する場合を除いて請求項2〜4のいずれか1項に記載の可溶性IRM−ポリマー複合体。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56086204P | 2004-04-09 | 2004-04-09 | |
US61719604P | 2004-10-08 | 2004-10-08 | |
PCT/US2005/011997 WO2005110013A2 (en) | 2004-04-09 | 2005-04-08 | Methods, compositions, and preparations for delivery of immune response modifiers |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007532572A JP2007532572A (ja) | 2007-11-15 |
JP2007532572A5 true JP2007532572A5 (ja) | 2008-04-24 |
Family
ID=35394580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007507539A Withdrawn JP2007532572A (ja) | 2004-04-09 | 2005-04-08 | 免疫反応調整剤を送達させるための方法、組成物および調製物 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20070166384A1 (ja) |
EP (1) | EP1735010A4 (ja) |
JP (1) | JP2007532572A (ja) |
AU (1) | AU2005244260B2 (ja) |
CA (1) | CA2562283A1 (ja) |
WO (1) | WO2005110013A2 (ja) |
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WO2006026394A2 (en) * | 2004-08-27 | 2006-03-09 | 3M Innovative Properties Company | Method of eliciting an immune response against hiv |
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-
2005
- 2005-04-08 WO PCT/US2005/011997 patent/WO2005110013A2/en active Application Filing
- 2005-04-08 CA CA002562283A patent/CA2562283A1/en not_active Abandoned
- 2005-04-08 JP JP2007507539A patent/JP2007532572A/ja not_active Withdrawn
- 2005-04-08 EP EP05778021A patent/EP1735010A4/en not_active Withdrawn
- 2005-04-08 AU AU2005244260A patent/AU2005244260B2/en not_active Ceased
- 2005-04-08 US US10/599,730 patent/US20070166384A1/en not_active Abandoned
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