JP2007525958A5 - - Google Patents

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Publication number
JP2007525958A5
JP2007525958A5 JP2006517337A JP2006517337A JP2007525958A5 JP 2007525958 A5 JP2007525958 A5 JP 2007525958A5 JP 2006517337 A JP2006517337 A JP 2006517337A JP 2006517337 A JP2006517337 A JP 2006517337A JP 2007525958 A5 JP2007525958 A5 JP 2007525958A5
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JP
Japan
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substituted
unsubstituted
formula
integer
copolymer
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JP2006517337A
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English (en)
Japanese (ja)
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JP4701169B2 (ja
JP2007525958A (ja
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Priority claimed from PCT/US2004/019296 external-priority patent/WO2005012407A2/en
Publication of JP2007525958A publication Critical patent/JP2007525958A/ja
Publication of JP2007525958A5 publication Critical patent/JP2007525958A5/ja
Application granted granted Critical
Publication of JP4701169B2 publication Critical patent/JP4701169B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006517337A 2003-06-30 2004-06-16 アデノウイルスのポリマーカプセル化 Expired - Fee Related JP4701169B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48406003P 2003-06-30 2003-06-30
US60/484,060 2003-06-30
PCT/US2004/019296 WO2005012407A2 (en) 2003-06-30 2004-06-16 Polymer encapsulation of adenoviruses

Publications (3)

Publication Number Publication Date
JP2007525958A JP2007525958A (ja) 2007-09-13
JP2007525958A5 true JP2007525958A5 (https=) 2009-02-26
JP4701169B2 JP4701169B2 (ja) 2011-06-15

Family

ID=34115316

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006517337A Expired - Fee Related JP4701169B2 (ja) 2003-06-30 2004-06-16 アデノウイルスのポリマーカプセル化

Country Status (8)

Country Link
US (1) US20050031579A1 (https=)
EP (1) EP1646684A4 (https=)
JP (1) JP4701169B2 (https=)
CN (1) CN1859926B (https=)
AU (1) AU2004260935A1 (https=)
CA (1) CA2536120A1 (https=)
MX (1) MXPA05013983A (https=)
WO (1) WO2005012407A2 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492400B2 (en) 2004-11-04 2016-11-15 Massachusetts Institute Of Technology Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
US9267937B2 (en) 2005-12-15 2016-02-23 Massachusetts Institute Of Technology System for screening particles
US8367113B2 (en) 2006-05-15 2013-02-05 Massachusetts Institute Of Technology Polymers for functional particles
WO2007150030A2 (en) 2006-06-23 2007-12-27 Massachusetts Institute Of Technology Microfluidic synthesis of organic nanoparticles
US9217129B2 (en) 2007-02-09 2015-12-22 Massachusetts Institute Of Technology Oscillating cell culture bioreactor
WO2008124632A1 (en) 2007-04-04 2008-10-16 Massachusetts Institute Of Technology Amphiphilic compound assisted nanoparticles for targeted delivery
EP2630966B1 (en) 2007-10-12 2017-04-19 Massachusetts Institute of Technology Vaccine nanotechnology
US8343498B2 (en) 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
US8277812B2 (en) 2008-10-12 2012-10-02 Massachusetts Institute Of Technology Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
US8343497B2 (en) 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
US8591905B2 (en) 2008-10-12 2013-11-26 The Brigham And Women's Hospital, Inc. Nicotine immunonanotherapeutics
EP2338520A1 (de) 2009-12-21 2011-06-29 Ludwig Maximilians Universität Konjugat mit Zielfindungsligand und dessen Verwendung
EP2538929A4 (en) 2010-02-25 2014-07-09 Univ Johns Hopkins DELAYED RELEASE OF THERAPIES IN A PART OF THE EYE
WO2012109363A2 (en) 2011-02-08 2012-08-16 The Johns Hopkins University Mucus penetrating gene carriers
JP5944622B2 (ja) * 2011-04-08 2016-07-05 株式会社ブリヂストン 遺伝子導入剤組成物
CN102205133B (zh) * 2011-05-16 2017-12-12 姚宏 一种多聚阳离子包被腺病毒组合物的制备方法及其应用
CN104203282A (zh) 2012-01-30 2014-12-10 艾瑞克有限公司 稳定的水性抗体组合物
US9533068B2 (en) 2012-05-04 2017-01-03 The Johns Hopkins University Drug loaded microfiber sutures for ophthalmic application
EA037448B1 (ru) * 2012-06-08 2021-03-30 Этрис Гмбх Способ доставки в легкие терапевтической мрнк с pei и фармацевтическая композиция
WO2014124006A1 (en) 2013-02-05 2014-08-14 The Johns Hopkins University Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof
AP2016009154A0 (en) * 2013-09-19 2016-04-30 Crucell Holland Bv Improved adenovirus formulations
WO2015175545A1 (en) 2014-05-12 2015-11-19 The Johns Hopkins University Highly stable biodegradable gene vector platforms for overcoming biological barriers
US9682100B2 (en) 2015-01-26 2017-06-20 International Business Machines Corporation Cationic polyamines for treatment of viruses
CN107635545A (zh) 2015-01-27 2018-01-26 约翰霍普金斯大学 用于增强粘膜表面处活性剂的输送的低渗水凝胶制剂
GB201708203D0 (en) * 2017-05-22 2017-07-05 Sagetis Biotech Sl Chemical compounds
US12496279B2 (en) 2019-04-11 2025-12-16 The Johns Hopkins University Nanoparticles for drug delivery to brain

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747469A (en) * 1991-03-06 1998-05-05 Board Of Regents, The University Of Texas System Methods and compositions comprising DNA damaging agents and p53
US5846945A (en) * 1993-02-16 1998-12-08 Onyx Pharmaceuticals, Inc. Cytopathic viruses for therapy and prophylaxis of neoplasia
FR2719316B1 (fr) * 1994-04-28 1996-05-31 Idm Nouveaux complexes d'acide nucléique et de polymère, leur procédé de préparation et leur utilisation pour la transfection de cellules.
US6221959B1 (en) * 1994-11-18 2001-04-24 Supratek Pharma, Inc. Polynucleotide compositions
JP4320054B2 (ja) * 1996-08-13 2009-08-26 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド ポリヌクレオチド送達のための組成物および方法
CN1181422A (zh) * 1996-10-31 1998-05-13 上海市肿瘤研究所 与生长因子受体结合的多肽所构建的基因转移载体
US5962429A (en) * 1996-11-22 1999-10-05 University Of Iowa Complexes of adenovirus with cationic molecules
DE19726186A1 (de) * 1997-06-20 1998-12-24 Boehringer Ingelheim Int Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen
FR2766195A1 (fr) * 1997-07-21 1999-01-22 Transgene Sa Polymeres cationiques, complexes associant lesdits polymeres cationiques et des substances therapeutiquement actives comprenant au moins une charges negative, notamment des acides nucleiques, et leur utilisation en therapie genique
MXPA00011312A (es) * 1998-05-20 2003-04-22 Expression Genetics Inc Un vehiculo de gen polimerico de poli-l.lisina injertada con polietilenglicol con porcion de enfoque hepatocitos.
US6333051B1 (en) * 1998-09-03 2001-12-25 Supratek Pharma, Inc. Nanogel networks and biological agent compositions thereof
JP2001199903A (ja) * 1999-11-09 2001-07-24 Eizo Mori 核酸含有複合体
US6586524B2 (en) * 2001-07-19 2003-07-01 Expression Genetics, Inc. Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier

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