JP2007521013A5 - - Google Patents
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- Publication number
- JP2007521013A5 JP2007521013A5 JP2006521315A JP2006521315A JP2007521013A5 JP 2007521013 A5 JP2007521013 A5 JP 2007521013A5 JP 2006521315 A JP2006521315 A JP 2006521315A JP 2006521315 A JP2006521315 A JP 2006521315A JP 2007521013 A5 JP2007521013 A5 JP 2007521013A5
- Authority
- JP
- Japan
- Prior art keywords
- term
- ambient temperature
- temperature
- mmhg
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49007003P | 2003-07-24 | 2003-07-24 | |
| US53936304P | 2004-01-26 | 2004-01-26 | |
| PCT/US2004/024318 WO2005010015A1 (en) | 2003-07-24 | 2004-07-26 | Method of purifying macrolides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007521013A JP2007521013A (ja) | 2007-08-02 |
| JP2007521013A5 true JP2007521013A5 (enExample) | 2009-07-16 |
Family
ID=34107827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006521315A Ceased JP2007521013A (ja) | 2003-07-24 | 2004-07-26 | マクロライドの精製方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7220357B2 (enExample) |
| EP (1) | EP1558622B1 (enExample) |
| JP (1) | JP2007521013A (enExample) |
| KR (1) | KR20060052874A (enExample) |
| AT (1) | ATE378345T1 (enExample) |
| CA (1) | CA2533548C (enExample) |
| DE (1) | DE602004010059T2 (enExample) |
| DK (1) | DK1558622T3 (enExample) |
| ES (1) | ES2297481T3 (enExample) |
| PL (1) | PL1558622T3 (enExample) |
| PT (1) | PT1558622E (enExample) |
| TW (1) | TW200523266A (enExample) |
| WO (1) | WO2005010015A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2494797T3 (es) * | 2003-12-05 | 2014-09-16 | Biocon Limited | Procedimiento para la purificación de tacrolimus |
| WO2006060616A1 (en) * | 2004-12-01 | 2006-06-08 | Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg | Processes for producing crystalline macrolides |
| US20060142565A1 (en) * | 2004-12-22 | 2006-06-29 | Vilmos Keri | Method of purifying tacrolimus |
| TW200736603A (en) * | 2005-12-07 | 2007-10-01 | Wyeth Corp | Methods for preparing crystalline rapamycin and measuring crystallinity of rapamycin compounds using differential scanning calorimetry |
| KR100859670B1 (ko) * | 2006-09-13 | 2008-09-23 | 동국제약 주식회사 | 타크로리무스를 고수율 및 고순도로 정제하는 방법 |
| WO2008057511A2 (en) * | 2006-11-06 | 2008-05-15 | Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Ascomycin and pimecrolimus having reduced levels of desmethylascomycin and 32-deoxy-32-epichloro-desmethylascomycin respectively, and methods for preparation thereof |
| KR100891313B1 (ko) * | 2007-08-17 | 2009-03-31 | (주) 제노텍 | 담체로 작용하는 흡착성 수지의 제공에 의한 트리사이클로화합물의 생산 및 추출 방법 |
| WO2010121203A1 (en) * | 2009-04-16 | 2010-10-21 | Ocean Spray Cranberries, Inc. | Phenolics extraction and use |
| CN106478664B (zh) * | 2016-08-29 | 2017-12-05 | 广东蓝宝制药有限公司 | 一种发酵液中提取纯化他克莫司的方法 |
| US10975097B2 (en) | 2017-05-01 | 2021-04-13 | Meda Ab | Process to convert technical ascomycin into purified pimecrolimus |
| CN108409751A (zh) * | 2018-02-24 | 2018-08-17 | 海正药业(杭州)有限公司 | 一种子囊霉素的纯化方法 |
| CN111693635A (zh) * | 2020-07-23 | 2020-09-22 | 北京和合医学诊断技术股份有限公司 | 检测血液中雷帕霉素含量的方法 |
| CN113325108B (zh) * | 2021-06-04 | 2022-12-09 | 山东霆科药业有限公司 | 一种他克莫司软膏的样品前处理方法 |
| CN115716839A (zh) * | 2022-11-15 | 2023-02-28 | 无锡福祈制药有限公司 | 一种依维莫司杂质的合成方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2121517C3 (de) | 1971-04-30 | 1974-06-27 | Leningradskij Nautschno-Issledowatelskij Institut Antibiotikow, Ssr, Leningrad (Sowjetunion) | Verfahren zur Gewinnung von Amphoterizin B |
| US3993749A (en) * | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
| US4160861A (en) * | 1977-10-03 | 1979-07-10 | Merck & Co., Inc. | Method for the separation of antibiotic macrolides |
| US4894366A (en) | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
| JP2639737B2 (ja) * | 1990-01-23 | 1997-08-13 | 寳酒造株式会社 | 新規ｒ１０６類化合物 |
| US5116756A (en) * | 1991-01-28 | 1992-05-26 | Merck & Co., Inc. | Process for producing FK-506 |
| US5494820A (en) | 1991-04-11 | 1996-02-27 | Pfizer Inc. | Streptomyces braegensis strain and its cultivation in a process for producing C9 -desoxo-FK-520 |
| US5091389A (en) * | 1991-04-23 | 1992-02-25 | Merck & Co., Inc. | Lipophilic macrolide useful as an immunosuppressant |
| DE69330747T2 (de) * | 1992-03-02 | 2002-05-29 | Pfizer Inc., New York | Desosamino-derivate von makroliden als immunosuppressive und antifungale mittel |
| UA41884C2 (uk) * | 1993-11-05 | 2001-10-15 | Амерікан Хоум Продактс Корпорейшн | Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів |
| US5622866A (en) * | 1994-06-23 | 1997-04-22 | Merck & Co., Inc. | Expression cassettes useful in construction of integrative and replicative expression vectors for Streptomyces |
| GB9618952D0 (en) | 1996-09-11 | 1996-10-23 | Sandoz Ltd | Process |
| GB9826882D0 (en) | 1998-12-07 | 1999-01-27 | Novartis Ag | Organic compounds |
| TW553946B (en) * | 1999-09-08 | 2003-09-21 | Fujisawa Pharmaceutical Co | Method for separating lactone-containing high-molecular weight compounds |
| ES2177373B1 (es) | 1999-11-26 | 2003-11-01 | Astur Pharma Sa | Preparacion de azitromicina en su forma no cristalina |
| FR2803307A1 (fr) * | 1999-12-30 | 2001-07-06 | Centre Nat Rech Scient | Lignees de lymphocytes t cd4 specifiques de type th1 et procede pour leur induction ex vivo |
| AU2001236543B2 (en) * | 2000-02-24 | 2005-02-03 | Teva Gyogyszergyar Reszvenytarsasag | Method of purifying a fermentation broth |
| AUPQ801700A0 (en) * | 2000-06-07 | 2000-06-29 | Peplin Research Pty Ltd | Enzyme and viral activation |
| AUPQ923100A0 (en) * | 2000-08-07 | 2000-08-31 | Peplin Research Pty Ltd | Treatment of prostate cancer |
| KR20040086369A (ko) * | 2002-02-13 | 2004-10-08 | 비오갈 기오기스제르갸르 알티. | 바이오매터로부터 마크롤라이드를 추출하는 방법 |
-
2004
- 2004-07-26 US US10/899,757 patent/US7220357B2/en not_active Expired - Fee Related
- 2004-07-26 EP EP04779384A patent/EP1558622B1/en not_active Expired - Lifetime
- 2004-07-26 TW TW093122295A patent/TW200523266A/zh unknown
- 2004-07-26 AT AT04779384T patent/ATE378345T1/de active
- 2004-07-26 ES ES04779384T patent/ES2297481T3/es not_active Expired - Lifetime
- 2004-07-26 JP JP2006521315A patent/JP2007521013A/ja not_active Ceased
- 2004-07-26 PT PT04779384T patent/PT1558622E/pt unknown
- 2004-07-26 KR KR1020067001618A patent/KR20060052874A/ko not_active Abandoned
- 2004-07-26 CA CA2533548A patent/CA2533548C/en not_active Expired - Fee Related
- 2004-07-26 DE DE602004010059T patent/DE602004010059T2/de not_active Expired - Lifetime
- 2004-07-26 DK DK04779384T patent/DK1558622T3/da active
- 2004-07-26 WO PCT/US2004/024318 patent/WO2005010015A1/en not_active Ceased
- 2004-07-26 PL PL04779384T patent/PL1558622T3/pl unknown
-
2007
- 2007-01-17 US US11/654,758 patent/US20070117976A1/en not_active Abandoned
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