JP2007516991A - 慢性静脈不全の治療のための赤ブドウの葉の水性抽出物及び血液循環改善剤を含む組成物 - Google Patents

慢性静脈不全の治療のための赤ブドウの葉の水性抽出物及び血液循環改善剤を含む組成物 Download PDF

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JP2007516991A
JP2007516991A JP2006546016A JP2006546016A JP2007516991A JP 2007516991 A JP2007516991 A JP 2007516991A JP 2006546016 A JP2006546016 A JP 2006546016A JP 2006546016 A JP2006546016 A JP 2006546016A JP 2007516991 A JP2007516991 A JP 2007516991A
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red grape
blood circulation
vitamin
composition according
aqueous extract
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JP2007516991A5 (enExample
Inventor
実 岡田
敏彰 堀江
光一 高橋
賢二 増田
Original Assignee
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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Publication of JP2007516991A publication Critical patent/JP2007516991A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2006546016A 2003-12-29 2004-12-18 慢性静脈不全の治療のための赤ブドウの葉の水性抽出物及び血液循環改善剤を含む組成物 Pending JP2007516991A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03029894A EP1550450A1 (en) 2003-12-29 2003-12-29 Composition comprising an aqueous extract of red vine leaves and a blood circulating-improving agent for the treatment of chronic venous insufficiencies
PCT/EP2004/014456 WO2005063268A1 (en) 2003-12-29 2004-12-18 Composition comprising an aqueous extract of red vine leaves and a blood circulation-improving agent for the treatment of chronic venous insufficiences

Publications (2)

Publication Number Publication Date
JP2007516991A true JP2007516991A (ja) 2007-06-28
JP2007516991A5 JP2007516991A5 (enExample) 2008-02-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006546016A Pending JP2007516991A (ja) 2003-12-29 2004-12-18 慢性静脈不全の治療のための赤ブドウの葉の水性抽出物及び血液循環改善剤を含む組成物

Country Status (13)

Country Link
US (1) US20050202110A1 (enExample)
EP (2) EP1550450A1 (enExample)
JP (1) JP2007516991A (enExample)
KR (1) KR20060130149A (enExample)
CN (1) CN1901929A (enExample)
AU (1) AU2004308616A1 (enExample)
BR (1) BRPI0418223A (enExample)
CA (1) CA2551580A1 (enExample)
EC (1) ECSP066685A (enExample)
MX (1) MXPA06007498A (enExample)
RU (1) RU2006127300A (enExample)
WO (1) WO2005063268A1 (enExample)
ZA (1) ZA200604097B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017524741A (ja) * 2014-08-12 2017-08-31 サノフィ−アヴェンティス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 飲用溶液を製造するための水溶性顆粒状材料
JP2017529314A (ja) * 2014-05-27 2017-10-05 エスエス製薬株式会社 冷え症等の全身症状改善用経口組成物

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JP2001122791A (ja) * 1999-10-20 2001-05-08 Boehringer Ingelheim Internatl Gmbh 下肢の慢性静脈不全の軽減および予防のための赤色ブドウ樹葉の水性抽出物よりなる食事補強剤
US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
US20040151794A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Method of improvement of blood circulation
EP1718168A1 (en) * 2004-02-19 2006-11-08 Boehringer Ingelheim International Gmbh Composition for the treatment of chronic venous insufficiencies comprising an extract of red vine leaves and an anti-inflammatory agent
EP2195000B1 (de) * 2007-08-31 2019-09-25 Sanofi-Aventis Deutschland GmbH Sprühfähige zusammensetzung enthaltend extrakt aus rotem weinlaub
DE102008012908A1 (de) * 2008-03-06 2009-09-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Methode zum anti-inflammatorischen und anti-ödematösen Schutz von explantiertem biologischen Material bis zu seiner Transplantation in Patienten
CN102246879B (zh) * 2011-06-24 2013-01-30 上海马陆葡萄公园有限公司 一种葡萄叶茶及其制备工艺
CN106389700A (zh) * 2016-12-05 2017-02-15 广东伊茗药业有限公司 一种舒缓腿部肿胀的贴剂
FR3075602B1 (fr) * 2017-12-21 2020-06-12 Urgo Recherche Innovation Et Developpement Produit de combinaison pour la prevention et le traitement des insuffisances veineuses chroniques
KR20200115927A (ko) * 2019-03-29 2020-10-08 주식회사 유니베라 포도잎 추출물 및 병풀 추출물을 포함하는 정맥순환 장애 개선용 조성물

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Publication number Priority date Publication date Assignee Title
EP0366156A1 (de) * 1984-01-28 1990-05-02 Roshdy Dr. Ismail Mittel zur Behandlung von Erkrankungen der Venen und des Analbereichs
WO1998051291A1 (fr) * 1997-05-13 1998-11-19 Remacle Jose Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie
JP2003511476A (ja) * 1999-10-20 2003-03-25 ベーリンガー インゲルハイム インターナシヨナル ゲゼルシヤフト ミツト ベシユレンクテル ハフツンク 赤色ブドウ樹葉の抽出物を用いる慢性静脈不全の治療方法
WO2003080062A1 (en) * 2002-03-25 2003-10-02 Silvia Perrella Segre Composition comprising vitamin b9, vitamin b6, lipoic acid and plant extracts for treating circulatory disorders

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US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
US20040151794A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Method of improvement of blood circulation
US20040146539A1 (en) * 2003-01-24 2004-07-29 Gupta Shyam K. Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
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EP1550452A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a antthrombotic agent for the treatment of chronic venous insufficiencies
EP1550451A1 (en) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Composition comprising an aqueous extract of red vine leaves and a diuretic for the treatment of chronic venous insufficiencies
EP1718168A1 (en) * 2004-02-19 2006-11-08 Boehringer Ingelheim International Gmbh Composition for the treatment of chronic venous insufficiencies comprising an extract of red vine leaves and an anti-inflammatory agent

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0366156A1 (de) * 1984-01-28 1990-05-02 Roshdy Dr. Ismail Mittel zur Behandlung von Erkrankungen der Venen und des Analbereichs
WO1998051291A1 (fr) * 1997-05-13 1998-11-19 Remacle Jose Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie
JP2003511476A (ja) * 1999-10-20 2003-03-25 ベーリンガー インゲルハイム インターナシヨナル ゲゼルシヤフト ミツト ベシユレンクテル ハフツンク 赤色ブドウ樹葉の抽出物を用いる慢性静脈不全の治療方法
WO2003080062A1 (en) * 2002-03-25 2003-10-02 Silvia Perrella Segre Composition comprising vitamin b9, vitamin b6, lipoic acid and plant extracts for treating circulatory disorders

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017529314A (ja) * 2014-05-27 2017-10-05 エスエス製薬株式会社 冷え症等の全身症状改善用経口組成物
US10695392B2 (en) 2014-05-27 2020-06-30 Ssp Co. Ltd Oral composition for improving systemic symptoms including sensitivity to cold
JP2017524741A (ja) * 2014-08-12 2017-08-31 サノフィ−アヴェンティス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 飲用溶液を製造するための水溶性顆粒状材料

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Publication number Publication date
ECSP066685A (es) 2006-10-25
CN1901929A (zh) 2007-01-24
RU2006127300A (ru) 2008-02-10
AU2004308616A1 (en) 2005-07-14
KR20060130149A (ko) 2006-12-18
EP1708727A1 (en) 2006-10-11
ZA200604097B (en) 2007-10-31
WO2005063268A1 (en) 2005-07-14
EP1550450A1 (en) 2005-07-06
CA2551580A1 (en) 2005-07-14
MXPA06007498A (es) 2006-08-31
BRPI0418223A (pt) 2007-04-27
US20050202110A1 (en) 2005-09-15

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