JP2007516991A5 - - Google Patents

Info

Publication number

JP2007516991A5

JP2007516991A5 JP2006546016A JP2006546016A JP2007516991A5 JP 2007516991 A5 JP2007516991 A5 JP 2007516991A5 JP 2006546016 A JP2006546016 A JP 2006546016A JP 2006546016 A JP2006546016 A JP 2006546016A JP 2007516991 A5 JP2007516991 A5 JP 2007516991A5

Authority

JP

Japan

Prior art keywords

composition according

leaves

aqueous extract

red

vitamin

Prior art date

2004-12-18

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 239000000203 mixture Substances 0.000 claims 19
• 241001593968 Vitis palmata Species 0.000 claims 9
• 239000006286 aqueous extract Substances 0.000 claims 9
• 230000017531 blood circulation Effects 0.000 claims 4
• 201000002816 chronic venous insufficiency Diseases 0.000 claims 4
• 201000002282 venous insufficiency Diseases 0.000 claims 4
• 241000978499 Brunnichia ovata Species 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 239000000546 pharmaceutical excipient Substances 0.000 claims 3
• GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
• CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
• PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims 2
• VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
• 239000000284 extract Substances 0.000 claims 2
• 229930003935 flavonoid Natural products 0.000 claims 2
• 150000002215 flavonoids Chemical class 0.000 claims 2
• 235000017173 flavonoids Nutrition 0.000 claims 2
• 230000002265 prevention Effects 0.000 claims 2
• RBCOYOYDYNXAFA-UHFFFAOYSA-L (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate Chemical compound CC1=NC=C(COP([O-])([O-])=O)C(C)=C1O RBCOYOYDYNXAFA-UHFFFAOYSA-L 0.000 claims 1
• ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 1
• 239000004129 EU approved improving agent Substances 0.000 claims 1
• WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
• AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims 1
• 229930003268 Vitamin C Natural products 0.000 claims 1
• 229930003427 Vitamin E Natural products 0.000 claims 1
• 239000013543 active substance Substances 0.000 claims 1
• 239000008280 blood Substances 0.000 claims 1
• 210000004369 blood Anatomy 0.000 claims 1
• FDJOLVPMNUYSCM-UVKKECPRSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7, Chemical compound [Co+3].N#[C-].C1([C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)[N-]\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O FDJOLVPMNUYSCM-UVKKECPRSA-L 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 230000000694 effects Effects 0.000 claims 1
• 238000000605 extraction Methods 0.000 claims 1
• WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
• 239000008103 glucose Substances 0.000 claims 1
• 235000013402 health food Nutrition 0.000 claims 1
• 235000008216 herbs Nutrition 0.000 claims 1
• 229960003512 nicotinic acid Drugs 0.000 claims 1
• 235000001968 nicotinic acid Nutrition 0.000 claims 1
• 239000011664 nicotinic acid Substances 0.000 claims 1
• 238000007911 parenteral administration Methods 0.000 claims 1
• 239000000825 pharmaceutical preparation Substances 0.000 claims 1
• 229940127557 pharmaceutical product Drugs 0.000 claims 1
• 150000008442 polyphenolic compounds Chemical class 0.000 claims 1
• 235000013824 polyphenols Nutrition 0.000 claims 1
• 238000002360 preparation method Methods 0.000 claims 1
• 239000008213 purified water Substances 0.000 claims 1
• IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 claims 1
• 235000012239 silicon dioxide Nutrition 0.000 claims 1
• 239000000377 silicon dioxide Substances 0.000 claims 1
• 239000006188 syrup Substances 0.000 claims 1
• 235000020357 syrup Nutrition 0.000 claims 1
• JZRWCGZRTZMZEH-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 claims 1
• 239000011718 vitamin C Substances 0.000 claims 1
• 235000019154 vitamin C Nutrition 0.000 claims 1
• 235000019165 vitamin E Nutrition 0.000 claims 1
• 229940046009 vitamin E Drugs 0.000 claims 1
• 239000011709 vitamin E Substances 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1