JP2007516180A - c−Met阻害薬としてのアリールメチルトリアゾロおよびイミダゾピラジン類 - Google Patents
c−Met阻害薬としてのアリールメチルトリアゾロおよびイミダゾピラジン類 Download PDFInfo
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- JP2007516180A JP2007516180A JP2006517562A JP2006517562A JP2007516180A JP 2007516180 A JP2007516180 A JP 2007516180A JP 2006517562 A JP2006517562 A JP 2006517562A JP 2006517562 A JP2006517562 A JP 2006517562A JP 2007516180 A JP2007516180 A JP 2007516180A
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- heteroalicyclic
- lower alkyl
- heteroaryl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48422003P | 2003-07-02 | 2003-07-02 | |
| PCT/US2004/020062 WO2005004607A1 (en) | 2003-07-02 | 2004-06-25 | Arylmethyl triazolo and imidazopyrazines as c-met inhibitors |
| US10/875,507 US7250417B2 (en) | 2003-07-02 | 2004-06-25 | Arylmethyl triazolo- and imidazopyrazines as c-Met inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516180A true JP2007516180A (ja) | 2007-06-21 |
| JP2007516180A5 JP2007516180A5 (enExample) | 2007-08-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006517562A Withdrawn JP2007516180A (ja) | 2003-07-02 | 2004-06-25 | c−Met阻害薬としてのアリールメチルトリアゾロおよびイミダゾピラジン類 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7250417B2 (enExample) |
| EP (1) | EP1643836A4 (enExample) |
| JP (1) | JP2007516180A (enExample) |
| BR (1) | BRPI0412003A (enExample) |
| CA (1) | CA2530589A1 (enExample) |
| MX (1) | MXPA06000091A (enExample) |
| WO (1) | WO2005004607A1 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011515343A (ja) * | 2008-03-03 | 2011-05-19 | タイガー ファーマテック | チロシンキナーゼ阻害薬 |
| JP2011530545A (ja) * | 2008-08-14 | 2011-12-22 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 腫瘍の治療のための二環式トリアゾール誘導体 |
| JP2012509903A (ja) * | 2008-11-25 | 2012-04-26 | ユニバーシティー オブ ロチェスター | Mlk阻害剤および使用方法 |
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| ES2376404T3 (es) * | 2008-05-22 | 2012-03-13 | Amgen Inc. | Heterociclos como inhibidores de proteínas cinasas. |
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| JP2012509342A (ja) | 2008-11-20 | 2012-04-19 | オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド | 置換ピロロ[2,3−b]−ピリジンおよび−ピラジン |
| EA019320B1 (ru) | 2008-12-22 | 2014-02-28 | Мерк Патент Гмбх | Новые полиморфные формы дигидрофосфата 6-(1-метил-1h-пиразол-4-ил)-2-{3-[5-(2-морфолин-4-илэтокси)пиримидин-2-ил]бензил}-2h-пиридазин-3-она и способы их получения |
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- 2004-06-25 BR BRPI0412003-5A patent/BRPI0412003A/pt not_active IP Right Cessation
- 2004-06-25 EP EP04776951A patent/EP1643836A4/en not_active Withdrawn
- 2004-06-25 CA CA002530589A patent/CA2530589A1/en not_active Abandoned
- 2004-06-25 US US10/875,507 patent/US7250417B2/en not_active Expired - Fee Related
- 2004-06-25 MX MXPA06000091A patent/MXPA06000091A/es unknown
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011515343A (ja) * | 2008-03-03 | 2011-05-19 | タイガー ファーマテック | チロシンキナーゼ阻害薬 |
| JP2011530545A (ja) * | 2008-08-14 | 2011-12-22 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 腫瘍の治療のための二環式トリアゾール誘導体 |
| JP2012509903A (ja) * | 2008-11-25 | 2012-04-26 | ユニバーシティー オブ ロチェスター | Mlk阻害剤および使用方法 |
| JP2013209418A (ja) * | 2009-12-31 | 2013-10-10 | Hutchison Medipharma Ltd | 特定のトリアゾロピリジンおよびトリアゾロピラジン、それらの組成物並びにそれらの使用方法 |
| JP2016155848A (ja) * | 2009-12-31 | 2016-09-01 | ハッチソン・メディファーマ・リミテッド | 特定のトリアゾロピリジンおよびトリアゾロピラジン、それらの組成物並びにそれらの使用方法 |
| JP2018009004A (ja) * | 2009-12-31 | 2018-01-18 | ハッチソン・メディファーマ・リミテッド | 特定のトリアゾロピリジンおよびトリアゾロピラジン、それらの組成物並びにそれらの使用方法 |
| JP2013529207A (ja) * | 2010-05-17 | 2013-07-18 | インコゼン セラピューティクス プライベート リミテッド | プロテインキナーゼ調節物質としての新規3,5−二置換−3h−イミダゾ[4,5−b]ピリジン化合物および3,5−二置換−3h−[1,2,3]トリアゾロ[4,5−b]ピリジン化合物 |
| JP2016164184A (ja) * | 2010-05-17 | 2016-09-08 | インコゼン セラピューティクス プライベート リミテッド | プロテインキナーゼ調節物質としての新規3,5−二置換−3h−イミダゾ[4,5−b]ピリジン化合物および3,5−二置換−3h−[1,2,3]トリアゾロ[4,5−b]ピリジン化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2530589A1 (en) | 2005-01-20 |
| BRPI0412003A (pt) | 2006-08-15 |
| EP1643836A4 (en) | 2006-12-06 |
| EP1643836A1 (en) | 2006-04-12 |
| WO2005004607A1 (en) | 2005-01-20 |
| US7250417B2 (en) | 2007-07-31 |
| MXPA06000091A (es) | 2006-04-07 |
| US20050107391A1 (en) | 2005-05-19 |
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