JP2007512302A5 - - Google Patents
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- Publication number
- JP2007512302A5 JP2007512302A5 JP2006540617A JP2006540617A JP2007512302A5 JP 2007512302 A5 JP2007512302 A5 JP 2007512302A5 JP 2006540617 A JP2006540617 A JP 2006540617A JP 2006540617 A JP2006540617 A JP 2006540617A JP 2007512302 A5 JP2007512302 A5 JP 2007512302A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- caspase
- alkyl
- inhibitor
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0327494.1A GB0327494D0 (en) | 2003-11-26 | 2003-11-26 | Novel imaging agents |
| PCT/GB2004/005003 WO2005053752A2 (en) | 2003-11-26 | 2004-11-26 | Novel imaging agents comprising caspase-3 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007512302A JP2007512302A (ja) | 2007-05-17 |
| JP2007512302A5 true JP2007512302A5 (https=) | 2008-01-31 |
Family
ID=29797853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006540617A Pending JP2007512302A (ja) | 2003-11-26 | 2004-11-26 | カスパーゼ−３阻害剤を含む新規な造影剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060275215A1 (https=) |
| EP (1) | EP1763371A2 (https=) |
| JP (1) | JP2007512302A (https=) |
| KR (1) | KR101236124B1 (https=) |
| CN (1) | CN1905904B (https=) |
| AU (1) | AU2004294784B2 (https=) |
| BR (1) | BRPI0416938A (https=) |
| CA (1) | CA2547236A1 (https=) |
| GB (1) | GB0327494D0 (https=) |
| IL (1) | IL175667A (https=) |
| MX (1) | MXPA06006045A (https=) |
| NO (1) | NO20062387L (https=) |
| RU (1) | RU2006117819A (https=) |
| WO (1) | WO2005053752A2 (https=) |
| ZA (1) | ZA200603887B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008505884A (ja) | 2004-07-08 | 2008-02-28 | エヌエスティー・ニューロサバイバル・テクノロジーズ・リミテッド | 疾患を検出する方法および化合物 |
| WO2006074799A2 (en) * | 2005-01-17 | 2006-07-20 | Universitätsklinikum Münster | 5-pyrrolidinylsulfonyl isatin derivatives |
| GB0502277D0 (en) * | 2005-02-04 | 2005-03-09 | Amersham Plc | Novel imaging agents |
| WO2007050319A1 (en) * | 2005-10-21 | 2007-05-03 | Immunochemistry Technologies, Llc | In vivo detection of apoptosis |
| GB0610395D0 (en) * | 2006-05-25 | 2006-07-05 | Ge Healthcare Ltd | Novel imaging agents |
| GB0612333D0 (en) * | 2006-06-21 | 2006-08-02 | Ge Healthcare Ltd | Radiopharmaceutical products |
| PL2029178T3 (pl) * | 2006-06-21 | 2012-08-31 | Ge Healthcare Ltd | Produkty radiofarmaceutyczne |
| GB0718957D0 (en) * | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Optical imaging agents |
| KR100845010B1 (ko) * | 2007-08-29 | 2008-07-08 | 한국생명공학연구원 | Ｎｉｒ／ｍｒ 이중모드 분자영상용 고분자 입자 및 그제조방법 |
| CA2722858C (en) * | 2008-04-30 | 2017-08-29 | Siemens Medical Solutions Usa, Inc. | Substrate based pet imaging agents |
| WO2010028156A2 (en) * | 2008-09-04 | 2010-03-11 | Board Of Regents, The University Of Texas System | Dual modality detection of apoptosis |
| EP2367816B1 (en) | 2008-09-05 | 2016-11-09 | Imperial Innovations Limited | Isatin derivatives for use as in vivo imaging agents |
| GB0818738D0 (en) * | 2008-10-13 | 2008-11-19 | Ge Healthcare Ltd | Imaging neuroflammation |
| WO2014186737A1 (en) * | 2013-05-16 | 2014-11-20 | The Johns Hopkins University | Compositions and methods for chemical exchange saturation transfer (cest) based magnetic resonance imaging (mri) |
| WO2017053864A1 (en) * | 2015-09-23 | 2017-03-30 | Intracellular Technologies, Llc | Cysteine protease inhibitors |
| CN107655871A (zh) * | 2017-09-12 | 2018-02-02 | 重庆医科大学 | 一种阿仑膦酸钠的高灵敏宽检测范围荧光检测新方法 |
| KR20240132016A (ko) * | 2021-12-08 | 2024-09-02 | 사이토사이트 바이오파마 인코포레이티드 | 그랜자임 b에 특이적인 화합물 및 그의 용도 |
| TW202508601A (zh) * | 2023-06-07 | 2025-03-01 | 美商塞托賽特生物製藥股份有限公司 | 對顆粒酶ｂ具有特異性之化合物之前驅藥及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5601801A (en) * | 1994-08-02 | 1997-02-11 | Merck Frosst Canada, Inc. | Radiolabelled angiotensin converting enzyme inhibitors |
| AR016384A1 (es) * | 1997-07-30 | 2001-07-04 | Smithkline Beecham Corp | Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta. |
| US6589503B1 (en) * | 1998-06-20 | 2003-07-08 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
| NO20002644D0 (no) * | 2000-05-23 | 2000-05-23 | Nycomed Imaging As | Kontrastmiddel |
| EP1283728A2 (en) * | 2000-05-23 | 2003-02-19 | Amersham Health AS | Contrast agents |
| WO2002070020A2 (en) * | 2001-03-02 | 2002-09-12 | University Of Western Ontario | Polymer precursors of radiolabeled compounds, and methods of making and using the same |
| WO2004028449A2 (en) * | 2002-09-24 | 2004-04-08 | The General Hospital Corporation | Azulene dimer-quenched, near-infrared fluorescent probes |
| CA2514441A1 (en) * | 2003-02-07 | 2004-10-19 | Merck Frosst Canada & Co. | Irreversible caspase-3 inhibitors as active site probes |
| PE20050159A1 (es) * | 2003-05-27 | 2005-04-19 | Vertex Pharma | Derivados de acido 3-[2-(3-amino-2-oxo-2h-piridin-1-il)-acetilamino]-4-oxo-pentanoico como inhibidores de caspasa |
-
2003
- 2003-11-26 GB GBGB0327494.1A patent/GB0327494D0/en not_active Ceased
-
2004
- 2004-11-26 US US10/560,509 patent/US20060275215A1/en not_active Abandoned
- 2004-11-26 JP JP2006540617A patent/JP2007512302A/ja active Pending
- 2004-11-26 CA CA002547236A patent/CA2547236A1/en not_active Abandoned
- 2004-11-26 KR KR1020067010133A patent/KR101236124B1/ko not_active Expired - Fee Related
- 2004-11-26 EP EP04805892A patent/EP1763371A2/en not_active Ceased
- 2004-11-26 RU RU2006117819/15A patent/RU2006117819A/ru not_active Application Discontinuation
- 2004-11-26 CN CN2004800406077A patent/CN1905904B/zh not_active Expired - Fee Related
- 2004-11-26 MX MXPA06006045A patent/MXPA06006045A/es active IP Right Grant
- 2004-11-26 AU AU2004294784A patent/AU2004294784B2/en not_active Expired - Fee Related
- 2004-11-26 WO PCT/GB2004/005003 patent/WO2005053752A2/en not_active Ceased
- 2004-11-26 BR BRPI0416938-7A patent/BRPI0416938A/pt not_active IP Right Cessation
-
2006
- 2006-05-15 ZA ZA200603887A patent/ZA200603887B/en unknown
- 2006-05-16 IL IL175667A patent/IL175667A/en not_active IP Right Cessation
- 2006-05-24 NO NO20062387A patent/NO20062387L/no not_active Application Discontinuation
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