JP2007512256A5 - - Google Patents

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Publication number
JP2007512256A5
JP2007512256A5 JP2006540036A JP2006540036A JP2007512256A5 JP 2007512256 A5 JP2007512256 A5 JP 2007512256A5 JP 2006540036 A JP2006540036 A JP 2006540036A JP 2006540036 A JP2006540036 A JP 2006540036A JP 2007512256 A5 JP2007512256 A5 JP 2007512256A5
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JP
Japan
Prior art keywords
group
alkyl
unsaturated
saturated
aromatic
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006540036A
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English (en)
Japanese (ja)
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JP2007512256A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/038777 external-priority patent/WO2005049632A1/en
Publication of JP2007512256A publication Critical patent/JP2007512256A/ja
Publication of JP2007512256A5 publication Critical patent/JP2007512256A5/ja
Pending legal-status Critical Current

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JP2006540036A 2003-11-18 2004-11-18 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法 Pending JP2007512256A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52320703P 2003-11-18 2003-11-18
PCT/US2004/038777 WO2005049632A1 (en) 2003-11-18 2004-11-18 Bifunctional macrolide heterocyclic compounds and methods of making and using the same

Publications (2)

Publication Number Publication Date
JP2007512256A JP2007512256A (ja) 2007-05-17
JP2007512256A5 true JP2007512256A5 (https=) 2007-12-13

Family

ID=34619585

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006540036A Pending JP2007512256A (ja) 2003-11-18 2004-11-18 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法

Country Status (4)

Country Link
US (1) US20070270357A1 (https=)
EP (1) EP1699808A1 (https=)
JP (1) JP2007512256A (https=)
WO (1) WO2005049632A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
EP1934237A2 (en) 2005-08-24 2008-06-25 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
EP3290427A1 (en) 2005-08-24 2018-03-07 Melinta Therapeutics, Inc. Triazole compounds and methods of making and using the same
EP2657238A4 (en) 2010-12-24 2014-06-18 Univ Tohoku Macrolide compound having anticancer effect

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629232A (en) * 1969-08-19 1971-12-21 Abbott Lab 2'-o-alkanoyl-4'-alkanoyloxy derivatives of erythromycin
US3681325A (en) * 1970-09-30 1972-08-01 Abbott Lab De(n-methyl)-n-substituted derivatives of erythromycin
US4404201A (en) * 1981-11-13 1983-09-13 Warner-Lambert Company Cephalosporins
US4546176A (en) * 1982-12-14 1985-10-08 Eisai Co., Ltd. 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same
US5232918A (en) * 1987-07-23 1993-08-03 Imperial Chemical Industries Plc Cephalosporin derivatives
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US6446032B1 (en) * 1990-09-21 2002-09-03 Massachusetts Institute Of Technology Designing compounds specifically inhibiting ribonucleic acid by binding to the minor groove
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
ATE150463T1 (de) * 1991-10-01 1997-04-15 Procter & Gamble Pharma Verfahren zur herstellung von antimikrobiellen quinolonyl-lactamen
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
MY113693A (en) * 1992-05-26 2002-05-31 Chugai Pharmaceutical Co Ltd Erythromycin derivatives having an enterokinesis stimulating action
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
US6274715B1 (en) * 1995-11-08 2001-08-14 Abbott Laboratories Tricyclic erythromycin derivatives
US5891643A (en) * 1995-11-14 1999-04-06 Abbott Laboratories Use of nuclear magnetic resonance to design ligands to target biomolecules
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
US5780605A (en) * 1997-09-08 1998-07-14 Abbott Laboratories 6,9-bridged erythromycin derivatives
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
US5955440A (en) * 1998-03-27 1999-09-21 Abbott Laboratories Macrolide LHRH antagonists
US6437119B1 (en) * 1998-05-07 2002-08-20 William Lawrence Truett Compounds formed from two or three antibiotics and their processes of preparation
WO1999063994A1 (en) * 1998-06-08 1999-12-16 Advanced Medicine, Inc. MULTIBINDING INHIBITORS OF HMG-CoA REDUCTASE
JP2002517423A (ja) * 1998-06-08 2002-06-18 アドバンスド メディスン インコーポレーテッド シクロオキシゲナーゼ−2の多結合インヒビター
US6420354B1 (en) * 1998-06-08 2002-07-16 Advanced Medicine, Inc. Sodium channel drugs and uses
US6288234B1 (en) * 1998-06-08 2001-09-11 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
US6541669B1 (en) * 1998-06-08 2003-04-01 Theravance, Inc. β2-adrenergic receptor agonists
IT1301968B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Derivati di eritromicina ad attivita' antibiotica
US6020521A (en) * 1998-08-26 2000-02-01 Abbott Laboratories Macrolide LHRH antagonists
US6479498B1 (en) * 1999-06-04 2002-11-12 Theravance, Inc. Sodium channel drugs and uses
DE60139257D1 (de) * 2000-04-27 2009-08-27 Scripps Research Inst Bifunktionelle antibiotika
WO2003015709A2 (en) * 2001-08-17 2003-02-27 The Trustees Of Princeton University Bifunctional glycopeptides antibiotics and combinatorial libraries thereof
US6576615B2 (en) * 2001-11-08 2003-06-10 Enanta Pharmaceuticals, Inc. 4′-O-substituted tylosin analogs
US6664240B2 (en) * 2001-11-15 2003-12-16 Enanta Pharmaceuticals, Inc. Tylosin derivatives having antibacterial activity
BR0307066A (pt) * 2002-01-22 2004-12-28 Upjohn Co Dispositivo médico resistente a infecção
AU2003219770B2 (en) * 2002-02-15 2008-10-09 Merckle Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US6710034B2 (en) * 2002-04-19 2004-03-23 Enanta Pharmaceuticals, Inc. 5-O-mycaminosyltylonide derivatives
US6753415B2 (en) * 2002-04-19 2004-06-22 Enanta Pharmaceuticals, Inc. 23-O-substituted 5-O-mycaminosyltylonide derivatives
US7064110B2 (en) * 2002-05-13 2006-06-20 Enanta Pharmaceuticals, Inc. 6-11 bicycle ketolide derivatives
US6878691B2 (en) * 2002-05-13 2005-04-12 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7129221B2 (en) * 2002-05-13 2006-10-31 Enanta Pharmaceuticals, Inc. 6,11-bicyclic erythromycin derivatives
AU2003264917A1 (en) * 2002-07-08 2004-01-23 Pliva - Istrazivacki Institut D.O.O. Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
RS20050008A (sr) * 2002-07-08 2007-06-04 Pliva-Istraživački Institut D.O.O., Nova jedinjenja,kompozicije i metode za lečenje inflamatornih oboljenja i stanja
EP1521763A2 (en) * 2002-07-08 2005-04-13 Pliva - Istrazivacki Institut d.o.o. Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use
TW200420573A (en) * 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
AU2004217919A1 (en) * 2003-03-05 2004-09-16 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using the same
WO2005042554A1 (en) * 2003-10-30 2005-05-12 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same

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