JP2007512256A - 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法 - Google Patents

二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法 Download PDF

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Publication number
JP2007512256A
JP2007512256A JP2006540036A JP2006540036A JP2007512256A JP 2007512256 A JP2007512256 A JP 2007512256A JP 2006540036 A JP2006540036 A JP 2006540036A JP 2006540036 A JP2006540036 A JP 2006540036A JP 2007512256 A JP2007512256 A JP 2007512256A
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group
alkyl
unsaturated
saturated
aromatic
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Pending
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JP2006540036A
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Japanese (ja)
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JP2007512256A5 (https=
Inventor
ジェイ ジェイ． ファーマー，
ジョエル エー． ゴールドバーグ，
アデグボイェーガ ケー． オイェラー，
ジョセフ エム． サルビーノ，
デーン エム． スプリンガー，
ジェニファー トラン，
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Melinta Subsidiary Corp
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Rib X Pharmaceuticals Inc
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Application filed by Rib X Pharmaceuticals Inc filed Critical Rib X Pharmaceuticals Inc
Publication of JP2007512256A publication Critical patent/JP2007512256A/ja
Publication of JP2007512256A5 publication Critical patent/JP2007512256A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
JP2006540036A 2003-11-18 2004-11-18 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法 Pending JP2007512256A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52320703P 2003-11-18 2003-11-18
PCT/US2004/038777 WO2005049632A1 (en) 2003-11-18 2004-11-18 Bifunctional macrolide heterocyclic compounds and methods of making and using the same

Publications (2)

Publication Number Publication Date
JP2007512256A true JP2007512256A (ja) 2007-05-17
JP2007512256A5 JP2007512256A5 (https=) 2007-12-13

Family

ID=34619585

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006540036A Pending JP2007512256A (ja) 2003-11-18 2004-11-18 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法

Country Status (4)

Country Link
US (1) US20070270357A1 (https=)
EP (1) EP1699808A1 (https=)
JP (1) JP2007512256A (https=)
WO (1) WO2005049632A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957228B2 (en) 2010-12-24 2015-02-17 Tohoku University Macrolide compound having anticancer effect

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
JP5383037B2 (ja) * 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
JP2009506063A (ja) 2005-08-24 2009-02-12 リブ−エックス ファーマシューティカルズ，インコーポレイテッド トリアゾール化合物ならびにこれを作製する方法および使用する方法
EP3290427A1 (en) 2005-08-24 2018-03-07 Melinta Therapeutics, Inc. Triazole compounds and methods of making and using the same

Citations (2)

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Publication number Priority date Publication date Assignee Title
JP2002517422A (ja) * 1998-06-08 2002-06-18 アドバンスド メディスン インコーポレーテッド 多価のマクロライド系抗生物質
WO2003070174A2 (en) * 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002517422A (ja) * 1998-06-08 2002-06-18 アドバンスド メディスン インコーポレーテッド 多価のマクロライド系抗生物質
WO2003070174A2 (en) * 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957228B2 (en) 2010-12-24 2015-02-17 Tohoku University Macrolide compound having anticancer effect

Also Published As

Publication number Publication date
US20070270357A1 (en) 2007-11-22
WO2005049632A1 (en) 2005-06-02
WO2005049632A8 (en) 2005-09-01
EP1699808A1 (en) 2006-09-13

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