JP2007510690A5 - - Google Patents
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- Publication number
- JP2007510690A5 JP2007510690A5 JP2006538767A JP2006538767A JP2007510690A5 JP 2007510690 A5 JP2007510690 A5 JP 2007510690A5 JP 2006538767 A JP2006538767 A JP 2006538767A JP 2006538767 A JP2006538767 A JP 2006538767A JP 2007510690 A5 JP2007510690 A5 JP 2007510690A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- water
- weight
- dosage form
- stabilizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 28
- 239000002552 dosage form Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 239000003381 stabilizer Substances 0.000 claims 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 7
- 150000002148 esters Chemical class 0.000 claims 6
- 239000013543 active substance Substances 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 5
- 235000014113 dietary fatty acids Nutrition 0.000 claims 4
- 229930195729 fatty acid Natural products 0.000 claims 4
- 239000000194 fatty acid Substances 0.000 claims 4
- 150000004665 fatty acids Chemical class 0.000 claims 4
- 235000011187 glycerol Nutrition 0.000 claims 4
- 108010010803 Gelatin Proteins 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 238000006136 alcoholysis reaction Methods 0.000 claims 3
- 238000005886 esterification reaction Methods 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- 229920000159 gelatin Polymers 0.000 claims 3
- 239000008273 gelatin Substances 0.000 claims 3
- 235000019322 gelatine Nutrition 0.000 claims 3
- 235000011852 gelatine desserts Nutrition 0.000 claims 3
- 239000011159 matrix material Substances 0.000 claims 3
- 238000002844 melting Methods 0.000 claims 3
- 230000008018 melting Effects 0.000 claims 3
- 239000004033 plastic Substances 0.000 claims 3
- 229920003023 plastic Polymers 0.000 claims 3
- 229920001223 polyethylene glycol Polymers 0.000 claims 3
- 239000000758 substrate Substances 0.000 claims 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 2
- 229940069428 antacid Drugs 0.000 claims 2
- 239000003159 antacid agent Substances 0.000 claims 2
- 230000001458 anti-acid effect Effects 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229920001328 Polyvinylidene chloride Polymers 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000009969 flowable effect Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- 239000008177 pharmaceutical agent Substances 0.000 claims 1
- 239000005033 polyvinylidene chloride Substances 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200302612A ES2235626B1 (es) | 2003-11-10 | 2003-11-10 | Formas de administracion masticables, no comprimidas dosificadas individualmente. |
| ESP200302612 | 2003-11-10 | ||
| PCT/EP2004/012658 WO2005048974A2 (en) | 2003-11-10 | 2004-11-09 | Non-tabletted, chewable, individually dosed administration forms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007510690A JP2007510690A (ja) | 2007-04-26 |
| JP2007510690A5 true JP2007510690A5 (https=) | 2007-12-06 |
| JP4879021B2 JP4879021B2 (ja) | 2012-02-15 |
Family
ID=34610359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538767A Expired - Fee Related JP4879021B2 (ja) | 2003-11-10 | 2004-11-09 | 非錠剤形チュアブル単回用投与形態 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20070134318A1 (https=) |
| EP (1) | EP1682097B1 (https=) |
| JP (1) | JP4879021B2 (https=) |
| KR (1) | KR20060116821A (https=) |
| CN (1) | CN1878542A (https=) |
| AR (1) | AR048050A1 (https=) |
| AT (1) | ATE492270T1 (https=) |
| AU (1) | AU2004290517B2 (https=) |
| BR (1) | BRPI0416215A (https=) |
| CA (1) | CA2548615A1 (https=) |
| CO (1) | CO5690531A2 (https=) |
| DE (1) | DE602004030706D1 (https=) |
| EC (1) | ECSP066553A (https=) |
| ES (2) | ES2235626B1 (https=) |
| IL (1) | IL175285A (https=) |
| MY (1) | MY143793A (https=) |
| NO (1) | NO20062723L (https=) |
| NZ (1) | NZ546375A (https=) |
| PE (1) | PE20050488A1 (https=) |
| RU (1) | RU2369379C2 (https=) |
| TW (1) | TW200526266A (https=) |
| UA (1) | UA90253C2 (https=) |
| UY (1) | UY28586A1 (https=) |
| WO (2) | WO2005048975A1 (https=) |
| ZA (1) | ZA200602416B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050089559A1 (en) | 2003-10-23 | 2005-04-28 | Istvan Szelenyi | Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
| US7960436B2 (en) | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
| SG174095A1 (en) | 2006-08-23 | 2011-09-29 | Valeant Pharmaceuticals Int | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
| US8993593B2 (en) | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
| CN101578259A (zh) | 2006-11-28 | 2009-11-11 | 威朗国际制药公司 | 作为钾通道调节剂的1,4-二氨基双环瑞替加滨类似物 |
| US8367684B2 (en) | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
| EP2170282A4 (en) * | 2007-06-27 | 2014-11-05 | Hanmi Pharm Ind Co Ltd | METHOD FOR PRODUCING A QUICKLY CRUSHING FORMULATION FOR ORAL ADMINISTRATION AND DEVICE FOR PREPARING AND PACKAGING THE FORMULATION |
| IL187159A0 (en) | 2007-07-03 | 2009-02-11 | Gur Megiddo | Use of metadoxine in relief of alcohol intoxication |
| US7786146B2 (en) | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
| WO2010013242A1 (en) | 2008-07-29 | 2010-02-04 | Alcobra Ltd. | Substituted pyridoxine-lactam carboxylate salts |
| EP2238976B1 (en) * | 2009-04-03 | 2012-06-27 | Hexal AG | Oral films comprising 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro- 1H-quinolin-2-one base or salts or hydrates thereof |
| CN102481291B (zh) | 2009-06-25 | 2015-10-21 | 阿尔考布拉有限公司 | 用于治疗、减轻症状、缓解、改善和预防认知疾病、障碍或病症的方法 |
| EA021368B1 (ru) * | 2011-06-21 | 2015-06-30 | Общество С Ограниченной Ответственностью "Консорциум-Пик" | Препарат кардиопротекторного действия |
| CN105911057B (zh) * | 2016-06-22 | 2018-10-19 | 扬州一洋制药有限公司 | 一种铝镁加混悬液的质量控制方法 |
| TWI886158B (zh) | 2019-10-10 | 2025-06-11 | 加拿大商再諾製藥公司 | 選擇性鉀通道調節劑之固態晶型 |
| MX2022005490A (es) | 2019-11-08 | 2022-08-10 | Xenon Pharmaceuticals Inc | Metodos para el tratamiento de trastornos depresivos. |
| US11957675B2 (en) | 2021-02-09 | 2024-04-16 | Xenon Pharmaceuticals Inc. | Methods and uses for treating anhedonia |
| CN113425694A (zh) * | 2021-07-02 | 2021-09-24 | 杭州蚕宝生物技术有限公司 | 一种石斛生物碱口腔崩解片剂及其制备方法 |
| US12053484B2 (en) | 2021-10-29 | 2024-08-06 | Medicated Chews, Llc | Simethicone chewable composition |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5645411A (en) * | 1979-09-20 | 1981-04-25 | Taiho Yakuhin Kogyo Kk | Poultice |
| FR2515035A1 (fr) * | 1981-10-26 | 1983-04-29 | Rhone Poulenc Sante | Nouvelle forme galenique solide pour administration par voie orale et son procede de fabrication |
| EP0409432A3 (en) * | 1989-07-20 | 1991-12-11 | Warner-Lambert Company | Confectionery delivery system |
| US5433951A (en) * | 1993-10-13 | 1995-07-18 | Bristol-Myers Squibb Company | Sustained release formulation containing captopril and method |
| JPH08319232A (ja) * | 1995-03-22 | 1996-12-03 | Takeda Chem Ind Ltd | 粉粒状組成物 |
| JPH0912463A (ja) * | 1995-06-23 | 1997-01-14 | Fujisawa Pharmaceut Co Ltd | 口中咀嚼用製剤 |
| US20030216303A1 (en) * | 1998-03-06 | 2003-11-20 | Michael Ambuhl | Emulsion preconcentrates containing cyclosporin or a macrolide |
| US6171615B1 (en) * | 1998-07-06 | 2001-01-09 | Gattefoss{acute over (e)} | Sustained release theophylline formulations, excipient systems and methods of production |
| US6060078A (en) * | 1998-09-28 | 2000-05-09 | Sae Han Pharm Co., Ltd. | Chewable tablet and process for preparation thereof |
| US6652880B1 (en) * | 1999-04-01 | 2003-11-25 | R.P. Scherer Technologies, Inc. | Oral pharmaceutical compositions containing long-chain triglycerides and liphophilic surfactants |
| DK1361864T3 (en) * | 2001-02-14 | 2014-03-03 | Gw Pharma Ltd | FLYLDENDE SPRAY FORMULATIONS FOR buccal administration of cannabinoids |
| US6692771B2 (en) * | 2001-02-23 | 2004-02-17 | Cima Labs Inc. | Emulsions as solid dosage forms for oral administration |
| RU2197094C1 (ru) * | 2001-12-26 | 2003-01-27 | Ставрулов Игорь Анатольевич | Жевательная резинка |
-
2003
- 2003-11-10 ES ES200302612A patent/ES2235626B1/es not_active Expired - Fee Related
-
2004
- 2004-03-11 WO PCT/EP2004/002513 patent/WO2005048975A1/en not_active Ceased
- 2004-10-28 UY UY28586A patent/UY28586A1/es not_active Application Discontinuation
- 2004-11-05 PE PE2004001080A patent/PE20050488A1/es not_active Application Discontinuation
- 2004-11-08 AR ARP040104105A patent/AR048050A1/es not_active Application Discontinuation
- 2004-11-08 MY MYPI20044643A patent/MY143793A/en unknown
- 2004-11-09 US US10/578,515 patent/US20070134318A1/en not_active Abandoned
- 2004-11-09 ES ES04797734T patent/ES2358332T3/es not_active Expired - Lifetime
- 2004-11-09 KR KR1020067009596A patent/KR20060116821A/ko not_active Ceased
- 2004-11-09 RU RU2006120087/15A patent/RU2369379C2/ru not_active IP Right Cessation
- 2004-11-09 NZ NZ546375A patent/NZ546375A/en unknown
- 2004-11-09 AT AT04797734T patent/ATE492270T1/de not_active IP Right Cessation
- 2004-11-09 WO PCT/EP2004/012658 patent/WO2005048974A2/en not_active Ceased
- 2004-11-09 JP JP2006538767A patent/JP4879021B2/ja not_active Expired - Fee Related
- 2004-11-09 AU AU2004290517A patent/AU2004290517B2/en not_active Ceased
- 2004-11-09 CA CA002548615A patent/CA2548615A1/en not_active Abandoned
- 2004-11-09 EP EP04797734A patent/EP1682097B1/en not_active Expired - Lifetime
- 2004-11-09 BR BRPI0416215-3A patent/BRPI0416215A/pt not_active IP Right Cessation
- 2004-11-09 CN CNA2004800330379A patent/CN1878542A/zh active Pending
- 2004-11-09 UA UAA200606335A patent/UA90253C2/ru unknown
- 2004-11-09 DE DE602004030706T patent/DE602004030706D1/de not_active Expired - Lifetime
- 2004-11-10 TW TW093134361A patent/TW200526266A/zh unknown
-
2006
- 2006-03-24 ZA ZA200602416A patent/ZA200602416B/xx unknown
- 2006-04-27 IL IL175285A patent/IL175285A/en not_active IP Right Cessation
- 2006-05-08 EC EC2006006553A patent/ECSP066553A/es unknown
- 2006-05-09 CO CO06043842A patent/CO5690531A2/es not_active Application Discontinuation
- 2006-06-12 NO NO20062723A patent/NO20062723L/no not_active Application Discontinuation
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