JP2007505033A5 - - Google Patents
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- JP2007505033A5 JP2007505033A5 JP2006519734A JP2006519734A JP2007505033A5 JP 2007505033 A5 JP2007505033 A5 JP 2007505033A5 JP 2006519734 A JP2006519734 A JP 2006519734A JP 2006519734 A JP2006519734 A JP 2006519734A JP 2007505033 A5 JP2007505033 A5 JP 2007505033A5
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- JP
- Japan
- Prior art keywords
- seq
- composition
- amino acid
- acid sequence
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 56
- 230000002163 immunogen Effects 0.000 claims 25
- 108091006027 G proteins Proteins 0.000 claims 23
- 102000030782 GTP binding Human genes 0.000 claims 23
- 108091000058 GTP-Binding Proteins 0.000 claims 23
- 125000003275 alpha amino acid group Chemical group 0.000 claims 19
- 230000002209 hydrophobic effect Effects 0.000 claims 17
- 108020001507 fusion proteins Proteins 0.000 claims 13
- 102000037865 fusion proteins Human genes 0.000 claims 13
- 230000004044 response Effects 0.000 claims 9
- 239000012634 fragment Substances 0.000 claims 8
- 230000002134 immunopathologic effect Effects 0.000 claims 8
- 241000725643 Respiratory syncytial virus Species 0.000 claims 7
- 230000028993 immune response Effects 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
- 239000002671 adjuvant Substances 0.000 claims 4
- 210000004899 c-terminal region Anatomy 0.000 claims 4
- 239000003085 diluting agent Substances 0.000 claims 4
- 239000003937 drug carrier Substances 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 4
- 230000001681 protective effect Effects 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 3
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 206010014950 Eosinophilia Diseases 0.000 claims 2
- 101710085938 Matrix protein Proteins 0.000 claims 2
- 101710127721 Membrane protein Proteins 0.000 claims 2
- 206010061603 Respiratory syncytial virus infection Diseases 0.000 claims 2
- 102000002933 Thioredoxin Human genes 0.000 claims 2
- 229940037003 alum Drugs 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 229920002704 polyhistidine Polymers 0.000 claims 2
- 208000030925 respiratory syncytial virus infectious disease Diseases 0.000 claims 2
- 108060008226 thioredoxin Proteins 0.000 claims 2
- 229940094937 thioredoxin Drugs 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 1
- 230000036039 immunity Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 201000009732 pulmonary eosinophilia Diseases 0.000 claims 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48780403P | 2003-07-15 | 2003-07-15 | |
| US56758604P | 2004-05-03 | 2004-05-03 | |
| US10/888,805 US7368537B2 (en) | 2003-07-15 | 2004-07-09 | Subunit vaccine against respiratory syncytial virus infection |
| PCT/CA2004/001007 WO2005007189A1 (en) | 2003-07-15 | 2004-07-14 | Subunit vaccine against respiratory syncytial virus infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007505033A JP2007505033A (ja) | 2007-03-08 |
| JP2007505033A5 true JP2007505033A5 (OSRAM) | 2007-08-30 |
Family
ID=34084525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006519734A Pending JP2007505033A (ja) | 2003-07-15 | 2004-07-14 | 呼吸器合胞体得ウイルス感染に対するサブユニットワクチン |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7368537B2 (OSRAM) |
| EP (2) | EP2204188A1 (OSRAM) |
| JP (1) | JP2007505033A (OSRAM) |
| AT (1) | ATE451119T1 (OSRAM) |
| AU (1) | AU2004257363A1 (OSRAM) |
| CA (1) | CA2532164A1 (OSRAM) |
| DE (1) | DE602004024542D1 (OSRAM) |
| ES (1) | ES2337901T3 (OSRAM) |
| WO (1) | WO2005007189A1 (OSRAM) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE489968T1 (de) * | 2001-03-09 | 2010-12-15 | Id Biomedical Corp Quebec | Proteosom-liposaccharid-vakzine-adjuvans |
| US7255867B2 (en) * | 2002-11-15 | 2007-08-14 | Id Biomedical Corporation Of Quebec | Vaccine |
| US7368537B2 (en) * | 2003-07-15 | 2008-05-06 | Id Biomedical Corporation Of Quebec | Subunit vaccine against respiratory syncytial virus infection |
| WO2005042017A1 (en) | 2003-10-22 | 2005-05-12 | Id Biomedical Corporation Of Quebec | Compositions and methods for activating innate and allergic immunity |
| SG186686A1 (en) * | 2004-06-25 | 2013-01-30 | Id Biomedical Corp Quebec | Compositions and methods for treating neurological disorders |
| ES2719406T3 (es) | 2007-12-24 | 2019-07-10 | Id Biomedical Corp Quebec | Antígenos recombinantes del VSR |
| WO2010006447A1 (en) * | 2008-07-18 | 2010-01-21 | Id Biomedical Corporation Of Quebec | Chimeric respiratory syncytial virus polypeptide antigens |
| US20110318376A1 (en) * | 2008-12-24 | 2011-12-29 | University Of Rochester | Recombinant expression of self-folding neutralizing epitope-bearing subdomains of the respiratory syncytial virus attachment and fusion proteins |
| CN102215861B (zh) * | 2009-06-19 | 2014-10-08 | 艾金株式会社 | 宫颈癌疫苗 |
| WO2010149745A1 (en) | 2009-06-24 | 2010-12-29 | Glaxosmithkline Biologicals S.A. | Recombinant rsv antigens |
| AU2010264686A1 (en) | 2009-06-24 | 2012-01-19 | Glaxosmithkline Biologicals S.A. | Vaccine |
| BR112012000826B1 (pt) | 2009-07-06 | 2022-07-26 | Variation Biotechnologies Inc | Método para a preparação de vesículas |
| WO2011005772A1 (en) | 2009-07-06 | 2011-01-13 | Variation Biotechnologies, Inc. | Methods for preparing vesicles and formulations produced therefrom |
| EP4218799A1 (en) | 2009-07-15 | 2023-08-02 | GlaxoSmithKline Biologicals S.A. | Rsv f protein compositions and methods for making same |
| AU2010279492B2 (en) * | 2009-08-04 | 2015-04-09 | The Government Of The United States Of America, As Represented By The Secretary, Department Of The Health And Human Services, Centers For Disease Control And Prevention | Anti-RSV immunogens and methods of immunization |
| AU2010293902A1 (en) | 2009-09-10 | 2012-03-22 | Novartis Ag | Combination vaccines against respiratory tract diseases |
| US8730396B2 (en) * | 2010-06-23 | 2014-05-20 | MindTree Limited | Capturing events of interest by spatio-temporal video analysis |
| CN103096922B (zh) | 2010-07-06 | 2019-08-06 | 变异生物技术公司 | 用于治疗流行性感冒的组合物和方法 |
| HRP20161352T1 (hr) * | 2010-07-06 | 2016-12-02 | Glaxosmithkline Biologicals Sa | Čestice nalik na virione za unos samoreplicirajućih molekula rna |
| ES2586580T3 (es) * | 2010-07-06 | 2016-10-17 | Glaxosmithkline Biologicals Sa | Inmunización de mamíferos grandes con dosis bajas de ARN |
| HUE026646T2 (en) | 2010-07-06 | 2016-07-28 | Glaxosmithkline Biologicals Sa | Preferred liposomes containing lipids of PKA value for delivery of RNA |
| ES2646669T3 (es) | 2010-07-06 | 2017-12-14 | Glaxosmithkline Biologicals Sa | Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN |
| DK2590675T3 (en) | 2010-07-07 | 2018-10-29 | Artificial Cell Tech Inc | ANTI-ANTI-COMPOSITIONS AND PROCEDURES FOR RESPIRATORY SYNCYTIAL VIRUS |
| EP4043040B1 (en) * | 2010-08-31 | 2023-01-11 | GlaxoSmithKline Biologicals SA | Small liposomes for delivery of immunogen-encoding rna |
| DK4226941T3 (da) * | 2010-08-31 | 2024-12-02 | Glaxosmithkline Biologicals Sa | Pegylerede liposomer til levering af immunogen-kodende rna |
| KR102266691B1 (ko) | 2010-10-11 | 2021-06-23 | 노파르티스 아게 | 항원 전달 플랫폼 |
| KR20120068647A (ko) * | 2010-12-18 | 2012-06-27 | 아이진 주식회사 | 개선된 면역반응을 유도하는 백신 |
| CN103501811B (zh) | 2011-01-13 | 2016-03-30 | 变异生物技术公司 | 用于治疗病毒感染的组合物和方法 |
| MX357319B (es) * | 2011-01-13 | 2018-07-04 | Variation Biotechnologies Inc | Metodo para preparar vesiculas y formulaciones producidas de las mismas. |
| RU2456020C1 (ru) * | 2011-03-30 | 2012-07-20 | Государственное образовательное учреждение дополнительного профессионального образования Российская медицинская академия последипломного образования Федерального агентства по здравоохранению и социальному развитию (ГОУ ДПО РМАПО Росздрава) | Способ профилактики гриппа и острых респираторных инфекций у детей с бронхиальной астмой |
| CA2834349A1 (en) * | 2011-04-26 | 2012-11-01 | Molecular Express, Inc. | Liposomal formulations |
| WO2012158613A1 (en) | 2011-05-13 | 2012-11-22 | Novartis Ag | Pre-fusion rsv f antigens |
| US11896636B2 (en) | 2011-07-06 | 2024-02-13 | Glaxosmithkline Biologicals Sa | Immunogenic combination compositions and uses thereof |
| EP2802353A4 (en) | 2012-01-12 | 2015-12-02 | Variation Biotechnologies Inc | COMPOSITIONS AND METHOD FOR THE TREATMENT OF VIRUS INFECTIONS |
| US20150079077A1 (en) | 2012-01-27 | 2015-03-19 | Variation Biotechnologies, Inc. | Methods and compositions for therapeutic agents |
| SI2879702T1 (sl) | 2012-08-01 | 2020-02-28 | Bavarian Nordic A/S | Cepivo na osnovi rekombinantnega modificiranega virusa vakcinacije Ankara (MVA) proti respiratornemu sincitialnemu virusu (RSV) |
| WO2014024026A1 (en) | 2012-08-06 | 2014-02-13 | Glaxosmithkline Biologicals S.A. | Method for eliciting in infants an immune response against rsv and b. pertussis |
| US20140037680A1 (en) | 2012-08-06 | 2014-02-06 | Glaxosmithkline Biologicals, S.A. | Novel method |
| EP3030260A1 (en) | 2013-08-05 | 2016-06-15 | GlaxoSmithKline Biologicals S.A. | Combination immunogenic compositions |
| US9415101B2 (en) * | 2013-09-25 | 2016-08-16 | Sequoia Sciences, Inc. | Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections |
| KR101695518B1 (ko) * | 2014-09-30 | 2017-01-12 | 이화여자대학교 산학협력단 | 호흡기 신시치아 바이러스 범용 백신 |
| US10835601B2 (en) | 2015-11-10 | 2020-11-17 | Ohio State Innovation Foundation | Methods and compositions related to accelerated humoral affinity |
| US11773143B2 (en) | 2017-10-13 | 2023-10-03 | Trellis Bioscience, Llc | Conformational epitopes in respiratory syncytial virus G protein central conserved region |
| CA3107037A1 (en) | 2018-08-08 | 2020-02-13 | Trellis Bioscience, Llc | Improved rsv passive and active vaccines |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4707543A (en) * | 1985-09-17 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines |
| US5726292A (en) * | 1987-06-23 | 1998-03-10 | Lowell; George H. | Immuno-potentiating systems for preparation of immunogenic materials |
| US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
| US5961970A (en) * | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
| PT854729E (pt) * | 1995-09-18 | 2004-08-31 | Us Army Med Res Mat Com Usamrm | Metodos melhorados para a producao de vacinas de subunidade multivalentes de proteossomas complexados nao covalentemente |
| US5848152A (en) | 1995-09-26 | 1998-12-08 | Motorola, Inc. | Communication device having interchangeable faceplates and active keypad cover |
| US6699478B1 (en) * | 1997-09-19 | 2004-03-02 | Wyeth Holdings Corporation | Enhanced immune response to attachment (G) protein of Respiratory Syncytial Virus |
| KR100550132B1 (ko) * | 1997-09-19 | 2006-02-08 | 와이어쓰 홀딩스 코포레이션 | 호흡 신시티아 바이러스의 부착 (지) 단백질에서 유도된펩티드 |
| WO2001060402A2 (en) | 2000-02-15 | 2001-08-23 | Intellivax International Inc. | Proteosome influenza vaccine |
| FR2819810B1 (fr) | 2001-01-23 | 2004-05-28 | Pf Medicament | Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin |
| ATE489968T1 (de) * | 2001-03-09 | 2010-12-15 | Id Biomedical Corp Quebec | Proteosom-liposaccharid-vakzine-adjuvans |
| US7368537B2 (en) * | 2003-07-15 | 2008-05-06 | Id Biomedical Corporation Of Quebec | Subunit vaccine against respiratory syncytial virus infection |
-
2004
- 2004-07-09 US US10/888,805 patent/US7368537B2/en not_active Expired - Fee Related
- 2004-07-14 DE DE602004024542T patent/DE602004024542D1/de not_active Expired - Lifetime
- 2004-07-14 EP EP09178294A patent/EP2204188A1/en not_active Withdrawn
- 2004-07-14 JP JP2006519734A patent/JP2007505033A/ja active Pending
- 2004-07-14 WO PCT/CA2004/001007 patent/WO2005007189A1/en not_active Ceased
- 2004-07-14 AU AU2004257363A patent/AU2004257363A1/en not_active Abandoned
- 2004-07-14 ES ES04761567T patent/ES2337901T3/es not_active Expired - Lifetime
- 2004-07-14 CA CA002532164A patent/CA2532164A1/en not_active Abandoned
- 2004-07-14 EP EP04761567A patent/EP1651264B1/en not_active Expired - Lifetime
- 2004-07-14 AT AT04761567T patent/ATE451119T1/de not_active IP Right Cessation
-
2008
- 2008-03-19 US US12/051,397 patent/US20080226673A1/en not_active Abandoned
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