JP2007504212A5 - - Google Patents
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- Publication number
- JP2007504212A5 JP2007504212A5 JP2006525214A JP2006525214A JP2007504212A5 JP 2007504212 A5 JP2007504212 A5 JP 2007504212A5 JP 2006525214 A JP2006525214 A JP 2006525214A JP 2006525214 A JP2006525214 A JP 2006525214A JP 2007504212 A5 JP2007504212 A5 JP 2007504212A5
- Authority
- JP
- Japan
- Prior art keywords
- drug release
- hours
- pharmaceutical composition
- release
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940079593 drug Drugs 0.000 claims 27
- 239000003814 drug Substances 0.000 claims 27
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- 239000000203 mixture Substances 0.000 claims 13
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 5
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 claims 4
- 229960004909 aminosalicylic acid Drugs 0.000 claims 4
- 238000004090 dissolution Methods 0.000 claims 4
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical compound NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 claims 4
- 229960004963 mesalazine Drugs 0.000 claims 4
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 4
- 229960001860 salicylate Drugs 0.000 claims 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 claims 4
- 229960004889 salicylic acid Drugs 0.000 claims 4
- KUNZMYAVFWDQKQ-UHFFFAOYSA-N 4-[(4-carboxy-3-hydroxyphenyl)diazenyl]-2-hydroxybenzoic acid Chemical compound C1=C(O)C(C(=O)O)=CC=C1N=NC1=CC=C(C(O)=O)C(O)=C1 KUNZMYAVFWDQKQ-UHFFFAOYSA-N 0.000 claims 3
- 238000013270 controlled release Methods 0.000 claims 2
- 230000003111 delayed effect Effects 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229940002612 prodrug Drugs 0.000 claims 2
- 239000000651 prodrug Substances 0.000 claims 2
- ITHFNJCQUCSZHH-UHFFFAOYSA-N 4-[(3-carboxy-4-hydroxyphenyl)diazenyl]-2-hydroxybenzoic acid Chemical compound C1=C(O)C(C(=O)O)=CC=C1N=NC1=CC=C(O)C(C(O)=O)=C1 ITHFNJCQUCSZHH-UHFFFAOYSA-N 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- QQBDLJCYGRGAKP-UHFFFAOYSA-N olsalazine Chemical compound C1=C(O)C(C(=O)O)=CC(N=NC=2C=C(C(O)=CC=2)C(O)=O)=C1 QQBDLJCYGRGAKP-UHFFFAOYSA-N 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49936503P | 2003-09-03 | 2003-09-03 | |
| US60/499,365 | 2003-09-03 | ||
| PCT/IB2004/003059 WO2005021009A2 (en) | 2003-09-03 | 2004-09-02 | Formulations and methods of treating inflammatory bowel disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007504212A JP2007504212A (ja) | 2007-03-01 |
| JP2007504212A5 true JP2007504212A5 (https=) | 2007-10-18 |
| JP5108304B2 JP5108304B2 (ja) | 2012-12-26 |
Family
ID=34272809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006525214A Expired - Fee Related JP5108304B2 (ja) | 2003-09-03 | 2004-09-02 | 炎症性腸疾患の治療用製剤及び方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7737133B2 (https=) |
| EP (1) | EP1663253B1 (https=) |
| JP (1) | JP5108304B2 (https=) |
| AT (1) | ATE489956T1 (https=) |
| AU (1) | AU2004267953A1 (https=) |
| CA (1) | CA2535923A1 (https=) |
| DE (1) | DE602004030353D1 (https=) |
| ES (1) | ES2353761T3 (https=) |
| IL (1) | IL173684A0 (https=) |
| MX (1) | MXPA06002048A (https=) |
| NO (1) | NO20061489L (https=) |
| WO (1) | WO2005021009A2 (https=) |
| ZA (1) | ZA200601356B (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004112756A1 (en) | 2003-06-26 | 2004-12-29 | Isa Odidi | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
| US7737133B2 (en) | 2003-09-03 | 2010-06-15 | Agi Therapeutics Ltd. | Formulations and methods of treating inflammatory bowel disease |
| US7825106B2 (en) * | 2003-09-03 | 2010-11-02 | Agi Therapeutics Ltd. | Modified release formulations and methods of treating inflammatory bowel disease |
| CA2555304C (en) | 2004-02-06 | 2016-06-28 | Nicolas Peter Shortis | Use of aminosalicylates in diarrhoea-predominent irritable bowel syndrome |
| US20080306029A1 (en) * | 2004-05-28 | 2008-12-11 | Salix Pharmaceuticals, Inc. | Prevention, Treatment, and Amelioration of Radiation Induced Enteritis |
| US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| US20090017110A1 (en) * | 2005-05-31 | 2009-01-15 | Capricorn Pharma Inc. | Modified release formulations of anti-irritability drugs |
| US20070015689A1 (en) * | 2005-06-23 | 2007-01-18 | Alza Corporation | Complexation of metal ions with polypeptides |
| US8921344B2 (en) * | 2006-11-03 | 2014-12-30 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| US7452872B2 (en) | 2005-08-24 | 2008-11-18 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| WO2007025146A2 (en) * | 2005-08-24 | 2007-03-01 | Salix Pharmaceuticals, Inc. | Balsalazide formulations and manufacture and use thereof |
| US8679545B2 (en) | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
| US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| CA2648280C (en) | 2006-04-03 | 2014-03-11 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| EP2050439B1 (en) * | 2006-08-11 | 2016-11-23 | Asahi Kasei Kabushiki Kaisha | Process for production of spherical granule containing slightly water-soluble substance |
| WO2008027557A2 (en) * | 2006-08-31 | 2008-03-06 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
| WO2008043107A2 (en) * | 2006-10-06 | 2008-04-10 | Alba Therapeutics Corporation | Use of tight junction antagonists to treat inflammatory bowel disease |
| ES2555066T3 (es) | 2006-11-17 | 2015-12-28 | Supernus Pharmaceuticals, Inc. | Formulaciones de liberación sostenida de topiramato |
| ES2645719T3 (es) * | 2006-12-04 | 2017-12-07 | Supernus Pharmaceuticals, Inc. | Formulaciones de topiramato de liberación inmediata mejoradas |
| WO2008085484A2 (en) * | 2006-12-28 | 2008-07-17 | Jacobus Pharmaceutical Company, Inc. | Treatment of inflammatory bowel disease with enteric coated formulations comprising 5-aminosalicylic acid or 4-aminosalicylic acid |
| GB2461822B (en) * | 2007-03-20 | 2011-09-21 | Isp Investments Inc | Meltable binder for melt granulation and/or pelletization |
| US20090036414A1 (en) * | 2007-08-02 | 2009-02-05 | Mutual Pharmaceutical Company, Inc. | Mesalamine Formulations |
| WO2009047802A2 (en) * | 2007-10-10 | 2009-04-16 | Lupin Limited | Novel colon targeted modified release bioadhesive formulation of 5-amino salicylic acid or its salts and metabolites thereof |
| US20090162434A1 (en) * | 2007-12-21 | 2009-06-25 | Disphar International Bv | Mesalazine tablet |
| EP2367421A4 (en) * | 2008-12-17 | 2013-03-13 | Altheus Therapeutics Inc | ORAL FORMULAS |
| CA3014688A1 (en) | 2008-12-19 | 2010-07-15 | Supernus Pharmaceuticals, Inc. | Use of molindone for the treatment of aggression, irritability, or impulsivity |
| WO2011123497A1 (en) | 2010-03-31 | 2011-10-06 | Supernus Pharmaceuticals Inc. | Stabilized formulations of cns compounds |
| US8597683B2 (en) * | 2010-11-30 | 2013-12-03 | Watson Pharmaceuticals, Inc. | Modified release tranexamic acid formulation |
| AU2013229990B2 (en) * | 2012-03-07 | 2017-07-06 | Santarus, Inc. | Controlled-release solid dosage forms of mesalamine |
| US20140141075A1 (en) | 2012-11-21 | 2014-05-22 | Warner Chilcott Company, Llc | 5-aminosalicylic acid capsule formulation |
| JP5897196B1 (ja) * | 2015-10-05 | 2016-03-30 | 大同化成工業株式会社 | 糖又は糖アルコール、膨潤型結合剤、崩壊剤及び高吸収性賦形剤を含む複合化造粒物及びその製造方法 |
| US20170119680A1 (en) | 2015-10-30 | 2017-05-04 | R.P. Scherer Technologies, Llc | Extended release film-coated capsules |
| JP7438113B2 (ja) * | 2018-01-03 | 2024-02-26 | フェリング ベスローテン フェンノートシャップ | アミノサリチレートの経口液体医薬組成物 |
| US12053447B2 (en) | 2019-06-25 | 2024-08-06 | NuBioPharma, LLC | Oral solution and powder to liquid compositions of balsalazide |
| CN112569915B (zh) * | 2020-12-27 | 2023-06-23 | 王晓玉 | 一种煤矿井水除铀吸附剂、及其制备方法和应用 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57500432A (https=) * | 1980-03-20 | 1982-03-11 | ||
| SE8002322L (sv) * | 1980-03-26 | 1981-09-27 | Pharmacia Ab | Medel for behandling av inflammatoriska tarmsjukdomar |
| US4374932A (en) * | 1981-06-08 | 1983-02-22 | G. D. Searle & Co. | 5-ASA Drug delivery system |
| ZA825384B (en) * | 1981-07-31 | 1983-05-25 | Tillott J B Ltd | Orally administrable pharmaceutical compositions |
| SE8303400D0 (sv) | 1983-06-15 | 1983-06-15 | Pharmacia Ab | Azo-bis-salicylsyra och salt derav samt deras farmaceutiska beredning och anvendning |
| SE8303399D0 (sv) * | 1983-06-15 | 1983-06-15 | Pharmacia Ab | Azo-bis-salicyl syra och salt derav, deras farmaceutiska beredning samt framstellning av syran |
| US4627851A (en) * | 1984-10-26 | 1986-12-09 | Alza Corporation | Colonic-therapeutic delivery system |
| US4693895A (en) * | 1984-10-26 | 1987-09-15 | Alza Corporation | Colon delivery system |
| US4705515A (en) * | 1984-10-26 | 1987-11-10 | Alza Corporation | Dosage form for administering drug of the colon |
| US4608048A (en) | 1984-12-06 | 1986-08-26 | Alza Corporation | Dispensing device with drug delivery patterns |
| US4904474A (en) * | 1988-01-25 | 1990-02-27 | Alza Corporation | Delivery of drug to colon by oral disage form |
| US5330998A (en) * | 1988-03-08 | 1994-07-19 | Pfizer Inc. | Thiazolidinedione derivatives as hypoglycemic agents |
| US5256675A (en) * | 1989-08-07 | 1993-10-26 | Fujisawa Pharmaceutical Co., Ltd. | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same |
| IE68593B1 (en) * | 1989-12-06 | 1996-06-26 | Sanofi Sa | Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them |
| IT1246382B (it) | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
| IL98087A (en) * | 1990-05-04 | 1996-11-14 | Perio Prod Ltd | Preparation for dispensing drugs in the colon |
| SE9002339L (sv) | 1990-07-04 | 1992-01-05 | Kabi Pharmacia Ab | Terapeutisk komposition och foerfarande foer dess framstaellning |
| US5519014A (en) | 1990-10-22 | 1996-05-21 | Borody; Thomas J. | Treatment of non-inflammatory and non-infectious bowel disorders |
| FR2692484B1 (fr) | 1992-06-22 | 1995-06-30 | Gouchet Franck | Nouvelle forme galenique de 4-asa a liberation controlee. |
| WO1995016451A1 (fr) | 1992-06-22 | 1995-06-22 | Franck Arno Gouchet | Comprimes a liberation controlee de 4-asa |
| ATE195252T1 (de) * | 1993-04-23 | 2000-08-15 | Novartis Erfind Verwalt Gmbh | Wirkstoffabgabevorrichtung mit gesteuerter freigabe |
| DK66493D0 (da) * | 1993-06-08 | 1993-06-08 | Ferring A S | Praeparater, isaer til brug ved behandling af inflammatoriske tarmsygdomme eller til at opnaa forbedret saarheling |
| JPH072650A (ja) * | 1993-06-18 | 1995-01-06 | Tanabe Seiyaku Co Ltd | 放出部位制御型製剤 |
| US5482718A (en) | 1994-03-23 | 1996-01-09 | Hoffmann-La Roche Inc. | Colon-targeted delivery system |
| EP0759303B1 (en) * | 1994-04-22 | 2002-10-16 | Yamanouchi Pharmaceutical Co. Ltd. | Colon-specific drug release system |
| GB9412394D0 (en) | 1994-06-21 | 1994-08-10 | Danbiosyst Uk | Colonic drug delivery composition |
| JPH0840941A (ja) * | 1994-07-29 | 1996-02-13 | Kanegafuchi Chem Ind Co Ltd | 炎症性腸疾患治療製剤 |
| US5608048A (en) * | 1995-06-05 | 1997-03-04 | Bristol-Myers Squibb Company | d4 T polymorphic Form 1 process |
| US6004581A (en) * | 1995-12-21 | 1999-12-21 | Farmaceutisk Laboratorium Ferring A/S | Modified release oral pharmaceutical composition and method for the treatment of bowel diseases |
| US5840332A (en) * | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
| DE19732903A1 (de) * | 1997-07-30 | 1999-02-04 | Falk Pharma Gmbh | Pellet-Formulierung zur Behandlung des Intestinaltraktes |
| JP2000103732A (ja) * | 1998-07-28 | 2000-04-11 | Tanabe Seiyaku Co Ltd | 腸内適所放出型製剤 |
| DE69924735T2 (de) | 1998-07-28 | 2006-01-19 | Tanabe Seiyaku Co., Ltd. | Zur wirkstoffabgabe an zielorten im darm fähige zubereitung |
| JP5068401B2 (ja) | 1998-09-28 | 2012-11-07 | カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップ | Ｈｐｍｃカプセルを使用する腸及び結腸への送達 |
| US6733789B1 (en) * | 1999-01-21 | 2004-05-11 | Biovail Laboratories, Inc. | Multiparticulate bisoprolol formulation |
| US6962717B1 (en) * | 1999-01-29 | 2005-11-08 | Disphar International B.V. | Pharmaceutical compositions |
| ITMI991316A1 (it) | 1999-06-14 | 2000-12-14 | Cip Ninety Two 92 S A | Composizioni farmaceutiche orali a rilascio modificato di mesalazina |
| DE10013029A1 (de) * | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Mehrschichtige Arzneiform für die Colonfreigabe |
| US6602915B2 (en) * | 2000-07-27 | 2003-08-05 | Rutgers, The State University Of New Jersey | Therapeutic azo-compounds for drug delivery |
| EP1315481B1 (de) | 2000-08-29 | 2006-12-06 | Mepha AG | Arzneimittel zur behandlung von darmerkrankungen |
| CA2359812C (en) | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
| SK287902B6 (sk) * | 2001-01-31 | 2012-03-02 | Evonik Rohm Gmbh | Multiparticulate drug form and method for the preparation thereof |
| US7737133B2 (en) | 2003-09-03 | 2010-06-15 | Agi Therapeutics Ltd. | Formulations and methods of treating inflammatory bowel disease |
| US7825106B2 (en) * | 2003-09-03 | 2010-11-02 | Agi Therapeutics Ltd. | Modified release formulations and methods of treating inflammatory bowel disease |
-
2004
- 2004-09-01 US US10/930,743 patent/US7737133B2/en not_active Expired - Lifetime
- 2004-09-02 ES ES04769427T patent/ES2353761T3/es not_active Expired - Lifetime
- 2004-09-02 WO PCT/IB2004/003059 patent/WO2005021009A2/en not_active Ceased
- 2004-09-02 AT AT04769427T patent/ATE489956T1/de not_active IP Right Cessation
- 2004-09-02 AU AU2004267953A patent/AU2004267953A1/en not_active Abandoned
- 2004-09-02 CA CA002535923A patent/CA2535923A1/en not_active Abandoned
- 2004-09-02 JP JP2006525214A patent/JP5108304B2/ja not_active Expired - Fee Related
- 2004-09-02 DE DE602004030353T patent/DE602004030353D1/de not_active Expired - Lifetime
- 2004-09-02 EP EP04769427A patent/EP1663253B1/en not_active Expired - Lifetime
- 2004-09-02 MX MXPA06002048A patent/MXPA06002048A/es not_active Application Discontinuation
-
2006
- 2006-02-13 IL IL173684A patent/IL173684A0/en unknown
- 2006-02-15 ZA ZA200601356A patent/ZA200601356B/en unknown
- 2006-04-03 NO NO20061489A patent/NO20061489L/no not_active Application Discontinuation
-
2010
- 2010-06-10 US US12/797,655 patent/US7928092B2/en not_active Expired - Lifetime
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