JP2007503831A5 - - Google Patents
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- Publication number
- JP2007503831A5 JP2007503831A5 JP2006525390A JP2006525390A JP2007503831A5 JP 2007503831 A5 JP2007503831 A5 JP 2007503831A5 JP 2006525390 A JP2006525390 A JP 2006525390A JP 2006525390 A JP2006525390 A JP 2006525390A JP 2007503831 A5 JP2007503831 A5 JP 2007503831A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- binding
- moiety
- amplification
- acid moiety
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 68
- 108020004707 nucleic acids Proteins 0.000 claims 47
- 102000039446 nucleic acids Human genes 0.000 claims 47
- 238000000034 method Methods 0.000 claims 46
- 230000003321 amplification Effects 0.000 claims 16
- 238000003199 nucleic acid amplification method Methods 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 15
- -1 nucleic acid compound Chemical class 0.000 claims 15
- 238000001514 detection method Methods 0.000 claims 12
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 6
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 6
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 6
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 6
- 102000004190 Enzymes Human genes 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 238000009396 hybridization Methods 0.000 claims 4
- 239000012528 membrane Substances 0.000 claims 4
- 238000003752 polymerase chain reaction Methods 0.000 claims 4
- 108020004414 DNA Proteins 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 239000011324 bead Substances 0.000 claims 2
- 239000000835 fiber Substances 0.000 claims 2
- 239000000945 filler Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000006249 magnetic particle Substances 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 230000035945 sensitivity Effects 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 2
- 239000002131 composite material Substances 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 239000012071 phase Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/653,321 | 2003-09-02 | ||
| US10/653,321 US7341837B2 (en) | 2003-09-02 | 2003-09-02 | Soluble analyte detection and amplification |
| PCT/US2004/028267 WO2005021731A2 (en) | 2003-09-02 | 2004-08-31 | Soluble analyte detection and amplification |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011218349A Division JP5597615B2 (ja) | 2003-09-02 | 2011-09-30 | 可溶性検体の検出および増幅 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007503831A JP2007503831A (ja) | 2007-03-01 |
| JP2007503831A5 true JP2007503831A5 (enExample) | 2007-10-18 |
| JP5547363B2 JP5547363B2 (ja) | 2014-07-09 |
Family
ID=34217868
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006525390A Expired - Fee Related JP5547363B2 (ja) | 2003-09-02 | 2004-08-31 | 可溶性検体の検出および増幅 |
| JP2011218349A Expired - Fee Related JP5597615B2 (ja) | 2003-09-02 | 2011-09-30 | 可溶性検体の検出および増幅 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011218349A Expired - Fee Related JP5597615B2 (ja) | 2003-09-02 | 2011-09-30 | 可溶性検体の検出および増幅 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7341837B2 (enExample) |
| EP (3) | EP1699934A4 (enExample) |
| JP (2) | JP5547363B2 (enExample) |
| CN (1) | CN1875116B (enExample) |
| AU (1) | AU2004269412B2 (enExample) |
| CA (1) | CA2538513C (enExample) |
| NZ (1) | NZ545485A (enExample) |
| WO (1) | WO2005021731A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7341837B2 (en) * | 2003-09-02 | 2008-03-11 | Lawton Robert L | Soluble analyte detection and amplification |
| US8669052B2 (en) | 2008-06-10 | 2014-03-11 | Rapid Pathogen Screening, Inc. | Lateral flow nucleic acid detector |
| EP1869469B1 (en) | 2005-03-17 | 2011-12-07 | Phigenics, LLC | Rapidly detecting and quantifying viable legionella |
| US7901932B2 (en) | 2005-03-17 | 2011-03-08 | Phigenics, Llc | Methods and compositions for rapidly detecting and quantifying viable Legionella |
| US8003314B2 (en) | 2007-04-16 | 2011-08-23 | Diagnostic Hybrids, Inc. | Methods for direct fluorescent antibody virus detection in liquids |
| US8609433B2 (en) | 2009-12-04 | 2013-12-17 | Rapid Pathogen Screening, Inc. | Multiplanar lateral flow assay with sample compressor |
| US20130196310A1 (en) | 2008-05-20 | 2013-08-01 | Rapid Pathogen Screening, Inc. | Method and Device for Combined Detection of Viral and Bacterial Infections |
| US8962260B2 (en) | 2008-05-20 | 2015-02-24 | Rapid Pathogen Screening, Inc. | Method and device for combined detection of viral and bacterial infections |
| US8815609B2 (en) | 2008-05-20 | 2014-08-26 | Rapid Pathogen Screening, Inc. | Multiplanar lateral flow assay with diverting zone |
| US9068981B2 (en) | 2009-12-04 | 2015-06-30 | Rapid Pathogen Screening, Inc. | Lateral flow assays with time delayed components |
| US20110086359A1 (en) * | 2008-06-10 | 2011-04-14 | Rapid Pathogen Screening, Inc. | Lateral flow assays |
| JP2010043934A (ja) * | 2008-08-12 | 2010-02-25 | Fujifilm Corp | 検出方法、検出用試料セル、検出用キット及び検出装置 |
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| US8698541B2 (en) * | 2011-02-17 | 2014-04-15 | Taiwan Semiconductor Manufacturing Company, Ltd. | Threshold voltage detection apparatus |
| CN104105966B (zh) | 2012-02-01 | 2016-10-26 | 弗·哈夫曼-拉罗切有限公司 | 用于检测多特异性结合物的结合搭档的方法 |
| CA2865575C (en) | 2012-02-27 | 2024-01-16 | Cellular Research, Inc. | Compositions and kits for molecular counting |
| WO2013148498A1 (en) | 2012-03-27 | 2013-10-03 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| CN102707066A (zh) * | 2012-04-01 | 2012-10-03 | 首都医科大学 | 一种基于抗体dna标记和高通量测序技术的蛋白质或其它分子的检测方法 |
| CN110964796B (zh) | 2013-08-28 | 2024-04-05 | 贝克顿迪金森公司 | 大规模平行单细胞分析 |
| US9909167B2 (en) * | 2014-06-23 | 2018-03-06 | The Board Of Trustees Of The Leland Stanford Junior University | On-slide staining by primer extension |
| EP3262192B1 (en) | 2015-02-27 | 2020-09-16 | Becton, Dickinson and Company | Spatially addressable molecular barcoding |
| WO2016160844A2 (en) | 2015-03-30 | 2016-10-06 | Cellular Research, Inc. | Methods and compositions for combinatorial barcoding |
| WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
| CN108026524A (zh) | 2015-09-11 | 2018-05-11 | 赛卢拉研究公司 | 用于核酸文库标准化的方法和组合物 |
| US10808287B2 (en) | 2015-10-23 | 2020-10-20 | Rapid Pathogen Screening, Inc. | Methods and devices for accurate diagnosis of infections |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| KR102638006B1 (ko) | 2016-09-26 | 2024-02-20 | 셀룰러 리서치, 인크. | 바코딩된 올리고뉴클레오티드 서열을 갖는 시약을 이용한 단백질 발현의 측정 |
| US11319583B2 (en) | 2017-02-01 | 2022-05-03 | Becton, Dickinson And Company | Selective amplification using blocking oligonucleotides |
| EP4345172A3 (en) | 2017-06-05 | 2024-07-03 | Becton, Dickinson and Company | Sample indexing for single cells |
| AU2019262048B2 (en) | 2018-05-03 | 2025-09-04 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| EP4545647A3 (en) | 2018-05-03 | 2025-07-09 | Becton, Dickinson and Company | Molecular barcoding on opposite transcript ends |
| CN118853827A (zh) | 2018-10-01 | 2024-10-29 | 贝克顿迪金森公司 | 确定5’转录物序列 |
| CN112969789A (zh) | 2018-11-08 | 2021-06-15 | 贝克顿迪金森公司 | 使用随机引发的单细胞全转录组分析 |
| EP3894552A1 (en) | 2018-12-13 | 2021-10-20 | Becton, Dickinson and Company | Selective extension in single cell whole transcriptome analysis |
| EP3914728B1 (en) | 2019-01-23 | 2023-04-05 | Becton, Dickinson and Company | Oligonucleotides associated with antibodies |
| CN113454234B (zh) | 2019-02-14 | 2025-03-18 | 贝克顿迪金森公司 | 杂合体靶向和全转录物组扩增 |
| EP4004231B1 (en) | 2019-07-22 | 2025-11-12 | Becton, Dickinson and Company | Single cell chromatin immunoprecipitation sequencing assay |
| CN114729350A (zh) | 2019-11-08 | 2022-07-08 | 贝克顿迪金森公司 | 使用随机引发获得用于免疫组库测序的全长v(d)j信息 |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| EP4097228B1 (en) | 2020-01-29 | 2024-08-14 | Becton, Dickinson and Company | Barcoded wells for spatial mapping of single cells through sequencing |
| WO2021173719A1 (en) | 2020-02-25 | 2021-09-02 | Becton, Dickinson And Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| EP4150118A1 (en) | 2020-05-14 | 2023-03-22 | Becton Dickinson and Company | Primers for immune repertoire profiling |
| EP4407030B1 (en) | 2020-06-02 | 2025-12-17 | Becton, Dickinson and Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| CN116194589A (zh) | 2020-07-31 | 2023-05-30 | 贝克顿迪金森公司 | 用于转座酶可及染色质的单细胞测定 |
| WO2022109343A1 (en) | 2020-11-20 | 2022-05-27 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| US12392771B2 (en) | 2020-12-15 | 2025-08-19 | Becton, Dickinson And Company | Single cell secretome analysis |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5344622A (en) * | 1976-09-30 | 1978-04-21 | Mochida Pharm Co Ltd | Immunologically measuring method |
| US4134792A (en) * | 1976-12-06 | 1979-01-16 | Miles Laboratories, Inc. | Specific binding assay with an enzyme modulator as a labeling substance |
| US4628037A (en) * | 1983-05-12 | 1986-12-09 | Advanced Magnetics, Inc. | Binding assays employing magnetic particles |
| US4957858A (en) * | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
| DE3433652A1 (de) * | 1984-09-13 | 1986-03-20 | Boehringer Mannheim Gmbh, 6800 Mannheim | Immunchemisches messverfahren fuer haptene und proteine |
| EP0253270B1 (en) * | 1986-07-14 | 1992-09-23 | Abbott Laboratories | Method for diagnostic immunoassay by solid phase separation |
| US5244816A (en) * | 1989-10-11 | 1993-09-14 | Akzo N.V. | Method for purifying chelator conjugated compounds |
| US5665539A (en) * | 1991-07-12 | 1997-09-09 | The Regents Of The University Of California | Immuno-polymerase chain reaction system for antigen detection |
| US5985548A (en) * | 1993-02-04 | 1999-11-16 | E. I. Du Pont De Nemours And Company | Amplification of assay reporters by nucleic acid replication |
| US5445936A (en) * | 1993-09-15 | 1995-08-29 | Ciba Corning Diagnostics Corp. | Method for non-competitive binding assays |
| US5648213A (en) * | 1994-08-30 | 1997-07-15 | Beckman Instruments, Inc. | Compositions and methods for use in detection of analytes |
| US6413783B1 (en) * | 1997-09-18 | 2002-07-02 | Meso Scale Technologies, Llc | Assay sonication apparatus and methodology |
| US7090804B2 (en) * | 1998-01-27 | 2006-08-15 | Clinical Mirco Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| US6686150B1 (en) * | 1998-01-27 | 2004-02-03 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| CA2329948A1 (en) * | 1998-06-09 | 1999-12-16 | Vijay Kumar | Solution-phase elisa |
| WO2001006016A2 (en) * | 1999-07-20 | 2001-01-25 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| IL148091A0 (en) | 1999-09-13 | 2002-09-12 | Nugen Technologies Inc | Methods and compositions for linear isothermal amplification of polynucleotide sequences |
| US6511809B2 (en) * | 2000-06-13 | 2003-01-28 | E. I. Du Pont De Nemours And Company | Method for the detection of an analyte by means of a nucleic acid reporter |
| DE10041766A1 (de) * | 2000-08-25 | 2002-03-14 | Friz Biochem Gmbh | Verfahren zur Markierung chemischer Substanzen |
| US6797481B1 (en) * | 2000-10-17 | 2004-09-28 | Dade Behring Marburg Gmbh | Simultaneous screening of multiple analytes |
| JP2002238565A (ja) * | 2001-02-13 | 2002-08-27 | Jsr Corp | ウイルス核酸増幅方法 |
| US20020197694A1 (en) * | 2001-06-20 | 2002-12-26 | Weiping Shao | Conjugates of reduced antibodies and biomolecules |
| US7341837B2 (en) | 2003-09-02 | 2008-03-11 | Lawton Robert L | Soluble analyte detection and amplification |
-
2003
- 2003-09-02 US US10/653,321 patent/US7341837B2/en not_active Expired - Lifetime
-
2004
- 2004-08-31 EP EP04782696A patent/EP1699934A4/en not_active Ceased
- 2004-08-31 WO PCT/US2004/028267 patent/WO2005021731A2/en not_active Ceased
- 2004-08-31 EP EP10150530A patent/EP2204456A1/en not_active Ceased
- 2004-08-31 CN CN200480032060.6A patent/CN1875116B/zh not_active Expired - Fee Related
- 2004-08-31 CA CA2538513A patent/CA2538513C/en not_active Expired - Fee Related
- 2004-08-31 EP EP14171566.4A patent/EP2808399B1/en not_active Expired - Lifetime
- 2004-08-31 JP JP2006525390A patent/JP5547363B2/ja not_active Expired - Fee Related
- 2004-08-31 AU AU2004269412A patent/AU2004269412B2/en not_active Ceased
- 2004-08-31 NZ NZ545485A patent/NZ545485A/en not_active IP Right Cessation
-
2010
- 2010-02-12 US US12/704,689 patent/US9181579B2/en not_active Expired - Fee Related
-
2011
- 2011-09-30 JP JP2011218349A patent/JP5597615B2/ja not_active Expired - Fee Related
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