JP2007502777A5 - - Google Patents

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Publication number
JP2007502777A5
JP2007502777A5 JP2006523414A JP2006523414A JP2007502777A5 JP 2007502777 A5 JP2007502777 A5 JP 2007502777A5 JP 2006523414 A JP2006523414 A JP 2006523414A JP 2006523414 A JP2006523414 A JP 2006523414A JP 2007502777 A5 JP2007502777 A5 JP 2007502777A5
Authority
JP
Japan
Prior art keywords
alkyl
heterocycloalkyl
alkoxycarbonyl
cycloalkoxy
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006523414A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007502777A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/026393 external-priority patent/WO2005016946A2/en
Publication of JP2007502777A publication Critical patent/JP2007502777A/ja
Publication of JP2007502777A5 publication Critical patent/JP2007502777A5/ja
Pending legal-status Critical Current

Links

JP2006523414A 2003-08-13 2004-08-13 腫瘍の処置のための白金錯体 Pending JP2007502777A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US48122603P 2003-08-13 2003-08-13
US51558003P 2003-10-30 2003-10-30
US51994303P 2003-11-14 2003-11-14
US52529503P 2003-11-25 2003-11-25
PCT/US2004/026393 WO2005016946A2 (en) 2003-08-13 2004-08-13 Platinum complexes for the treatment of tumors

Publications (2)

Publication Number Publication Date
JP2007502777A JP2007502777A (ja) 2007-02-15
JP2007502777A5 true JP2007502777A5 (enExample) 2007-09-27

Family

ID=34199238

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006523414A Pending JP2007502777A (ja) 2003-08-13 2004-08-13 腫瘍の処置のための白金錯体
JP2006523413A Pending JP2007502301A (ja) 2003-08-13 2004-08-13 腫瘍細胞の増殖を阻害するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006523413A Pending JP2007502301A (ja) 2003-08-13 2004-08-13 腫瘍細胞の増殖を阻害するための方法

Country Status (8)

Country Link
US (6) US7238372B2 (enExample)
EP (2) EP1664070B1 (enExample)
JP (2) JP2007502777A (enExample)
AT (2) ATE453653T1 (enExample)
AU (3) AU2004264421B2 (enExample)
CA (2) CA2535762A1 (enExample)
DE (2) DE602004024909D1 (enExample)
WO (2) WO2005016946A2 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2535762A1 (en) * 2003-08-13 2005-03-17 University Of South Florida Methods for inhibiting tumor cell proliferation
US20050288365A1 (en) * 2004-01-06 2005-12-29 Heidi Kay Platinum complexes and methods for inhibiting tumor cell proliferation
WO2005110477A2 (en) * 2004-04-09 2005-11-24 University Of South Florida Combination therapies for cancer and proliferative angiopathies
US7977500B2 (en) 2004-11-10 2011-07-12 University Of South Florida Platinum complexes for targeted drug delivery
WO2006065894A2 (en) * 2004-12-14 2006-06-22 University Of South Florida Methods for inhibiting stat3 signaling in immune cells
DE102004060934A1 (de) * 2004-12-17 2006-06-29 Wacker Chemie Ag Vernetzbare Polyorganosiloxanmassen
DE602006018299D1 (de) * 2005-06-30 2010-12-30 Bionumerik Pharmaceuticals Inc Platinanaloga mit monoazolligand
WO2007006019A1 (en) * 2005-07-06 2007-01-11 University Of South Florida Materials and methods for screening, diagnosis and prognosis of conditions associated with stat protein expression
US8133692B2 (en) * 2005-07-20 2012-03-13 University Of South Florida Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments
WO2007047623A2 (en) * 2005-10-14 2007-04-26 University Of South Florida Methods of inhibiting cell growth and methods of enhancing radiation responses
DE102006040647A1 (de) * 2006-08-30 2008-03-13 Robert Bosch Gmbh Handwerkzeugmaschine
WO2008144616A1 (en) 2007-05-18 2008-11-27 Heidi Kay Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods
US8895610B1 (en) * 2007-05-18 2014-11-25 Heldi Kay Platinum (IV) compounds targeting zinc finger domains
JP2010530411A (ja) * 2007-06-18 2010-09-09 プラットコー テクノロジーズ （プロプライエタリー） リミテッド 白金（ｉｖ）錯体
EP2190429B1 (en) * 2007-09-10 2016-04-20 Boston Biomedical, Inc. A novel group of stat3 pathway inhibitors and cancer stem cell pathway inhibitors
WO2010067335A1 (en) 2008-12-12 2010-06-17 Platco Technologies (Proprietary) Limited Platinum (iv) complexes for use in the treatment of proliferative diseases such as cancer
EP3327148B1 (en) 2010-06-18 2021-03-17 Myriad Genetics, Inc. Methods of predicting the status of brca1 and brca2 genes in a cancer cell
ES2704303T3 (es) 2010-08-24 2019-03-15 Dana Farber Cancer Inst Inc Procedimientos para la predicción de una respuesta contra el cáncer
ES2768344T3 (es) 2011-06-17 2020-06-22 Myriad Genetics Inc Métodos y materiales para evaluar el desequilibrio alélico
RU2491936C2 (ru) * 2011-07-11 2013-09-10 Борис Николаевич Анисимов Способ комплексного лечения больных паразитарными заболеваниями
JP6325453B2 (ja) 2011-12-21 2018-05-16 ミリアド・ジェネティックス・インコーポレイテッド ヘテロ接合性の消失（ｌｏｓｓｏｆｈｅｔｅｒｏｚｙｇｏｓｉｔｙ）を評価するための方法および材料
ES2687024T3 (es) 2012-02-23 2018-10-23 Children's Medical Center Corporation Procedimientos para predecir la respuesta contra el cáncer
CA2867434C (en) 2012-06-07 2021-10-12 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
US10308986B2 (en) 2013-03-14 2019-06-04 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
US10766915B2 (en) 2013-03-15 2020-09-08 Sherri Ann McFARLAND Metal-based coordination complexes as photodynamic compounds and their use
DK2981624T3 (da) 2013-04-05 2020-03-02 Myriad Genetics Inc Fremgangsmåder til vurdering af homolog rekombinationsdeficiens og forudsigelse af respons på cancerbehandling
US9650403B2 (en) * 2013-06-13 2017-05-16 Shanghai Institute Of Pharmaceutical Industry Platinum (II) compound, preparation method therefor, and pharmaceutical composition and application thereof
WO2015013565A1 (en) * 2013-07-25 2015-01-29 Nemucore Medical Innovations, Inc. Platinum derivatives for hydrophobic formulations
CA2931181C (en) 2013-12-09 2023-01-24 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
DK3686288T3 (da) 2014-08-15 2023-05-22 Myriad Genetics Inc Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens
JP6768716B2 (ja) 2015-06-19 2020-10-14 シン−ナット プロダクツ エンタープライズ エルエルシー カルボプラチンベースの共結晶の医薬組成物及びその用途
EP3297440A4 (en) 2015-06-19 2019-04-10 Syn-Nat Products Enterprise LLC COMPOSITION WITH CARBOPLATIN AND USE
KR20180021805A (ko) 2015-06-25 2018-03-05 신-낫 프로덕츠 엔터프라이즈 엘엘씨 약제학적 공-결정 조성물 및 이의 용도
CA3045306A1 (en) 2016-11-29 2018-06-07 Boston Biomedical, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
MX2020005310A (es) 2017-11-21 2020-10-08 Medoncare Pharmaceutical Co Ltd Producto de combinacion que comprende dicicloplatino y metodo de preparacion y uso del mismo.
CN112175014B (zh) * 2020-10-10 2021-08-20 中国药科大学 一种一氧化氮供体型四价铂衍生物、制备方法及其医药用途
EP4141127B1 (en) 2021-08-30 2024-10-09 Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln Method for assessing homologous recombination deficiency in ovarian cancer cells
WO2024063828A1 (en) 2022-09-21 2024-03-28 Oracle International Corporation Expert-optimal correlation: contamination factor identification for unsupervised anomaly detection

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177263A (en) * 1972-02-28 1979-12-04 Research Corporation Anti-animal tumor method
GB1432563A (en) 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
GR851932B (enExample) * 1984-08-14 1985-12-13 Engelhard Corp
JPS6296A (ja) * 1985-03-06 1987-01-06 Sumitomo Pharmaceut Co Ltd 脂溶性白金（２）錯体
JPH01156989A (ja) * 1987-09-25 1989-06-20 Ss Pharmaceut Co Ltd 新規白金錯体
ATE113054T1 (de) * 1988-02-02 1994-11-15 Johnson Matthey Inc Pt(iv) komplexe.
JP3520367B2 (ja) * 1994-12-22 2004-04-19 独立行政法人産業技術総合研究所 白金ニトロアンミン系錯体の製造方法
WO1996026949A1 (en) * 1995-02-28 1996-09-06 Debiopharm Sa Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same
US5922689A (en) * 1995-09-11 1999-07-13 Unitech Pharmaceuticals, Inc. Cisplatin analogs for cancer treatment
US5849790A (en) * 1995-11-17 1998-12-15 The University Of South Florida (Mono) ethylenediaminenitroplatinum (IV) complexes with ligands of oxides of nitrogen as possible anti-tumor agents
US6145688A (en) * 1996-07-17 2000-11-14 Smith; James C. Closure device for containers
US5977393A (en) 1997-11-21 1999-11-02 California Institute Of Technology Schiff base derivatives of ruthenium and osmium olefin metathesis catalysts
KR100246722B1 (ko) * 1997-12-30 2000-04-01 박호군 경구용 백금 착화합물 항암제 및 그 제조방법
JP2002535247A (ja) 1998-11-26 2002-10-22 ペンタファルム アクチェンゲゼルシャフト 輸送系複合体
JP2003525862A (ja) * 1999-01-27 2003-09-02 ザ ユニヴァーシティー オブ サウス フロリダ ヒト癌の治療のためのｓｔａｔ３シグナル伝達の阻害
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
US7033597B2 (en) 2000-10-13 2006-04-25 Université de Lausanne Intracellular delivery of biological effectors
CA2425610A1 (en) 2000-10-13 2002-04-18 University Of Lausanne Intracellular delivery of biological effectors by novel transporter peptide sequences
US7638122B2 (en) * 2003-03-07 2009-12-29 University Of South Florida Stat3 antagonists and their use as vaccines against cancer
WO2005002508A2 (en) 2003-06-11 2005-01-13 Access Pharmaceuticals, Inc. Macromolecular platinum chelates
CA2535762A1 (en) 2003-08-13 2005-03-17 University Of South Florida Methods for inhibiting tumor cell proliferation
US20050288365A1 (en) 2004-01-06 2005-12-29 Heidi Kay Platinum complexes and methods for inhibiting tumor cell proliferation
US7977500B2 (en) 2004-11-10 2011-07-12 University Of South Florida Platinum complexes for targeted drug delivery
WO2007006019A1 (en) 2005-07-06 2007-01-11 University Of South Florida Materials and methods for screening, diagnosis and prognosis of conditions associated with stat protein expression

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