CA2535584A1 - Platinum complexes for the treatment of tumors - Google Patents
Platinum complexes for the treatment of tumors Download PDFInfo
- Publication number
- CA2535584A1 CA2535584A1 CA002535584A CA2535584A CA2535584A1 CA 2535584 A1 CA2535584 A1 CA 2535584A1 CA 002535584 A CA002535584 A CA 002535584A CA 2535584 A CA2535584 A CA 2535584A CA 2535584 A1 CA2535584 A1 CA 2535584A1
- Authority
- CA
- Canada
- Prior art keywords
- cpa
- alkyl
- aryl
- heteroaryl
- platinum complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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| PCT/US2004/026393 WO2005016946A2 (en) | 2003-08-13 | 2004-08-13 | Platinum complexes for the treatment of tumors |
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| US10766915B2 (en) | 2013-03-15 | 2020-09-08 | Sherri Ann McFARLAND | Metal-based coordination complexes as photodynamic compounds and their use |
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| DE602004015811D1 (de) | 2003-08-13 | 2008-09-25 | Univ South Florida | Verfahren zur inhibierung der proliferation von tumorzellen, bei dem platinkomplexe eingesetzt werden |
| US20050288365A1 (en) | 2004-01-06 | 2005-12-29 | Heidi Kay | Platinum complexes and methods for inhibiting tumor cell proliferation |
| CA2563305A1 (en) * | 2004-04-09 | 2005-11-24 | University Of South Florida | Combination therapies for cancer and proliferative angiopathies |
| JP2008519859A (ja) | 2004-11-10 | 2008-06-12 | ユニバーシティー オブ サウス フロリダ | 標的化した薬物送達のための白金錯体 |
| US7951374B2 (en) | 2004-12-14 | 2011-05-31 | University Of South Florida | Methods for inhibiting STAT3 signaling in immune cells |
| DE102004060934A1 (de) * | 2004-12-17 | 2006-06-29 | Wacker Chemie Ag | Vernetzbare Polyorganosiloxanmassen |
| MX2007015852A (es) * | 2005-06-30 | 2008-02-22 | Bionumerik Pharmaceuticals Inc | Analogos de platino con ligandos de monoazol. |
| US20100190180A1 (en) * | 2005-07-06 | 2010-07-29 | Heidi Kay | Materials and Methods for Screening, Diagnosis and Prognosis of Conditions Associated With Stat Protein Expression |
| WO2007013946A2 (en) * | 2005-07-20 | 2007-02-01 | University Of South Florida | Method of predicting responsiveness to chemotherapy and selecting treatments |
| WO2007047623A2 (en) * | 2005-10-14 | 2007-04-26 | University Of South Florida | Methods of inhibiting cell growth and methods of enhancing radiation responses |
| DE102006040647A1 (de) * | 2006-08-30 | 2008-03-13 | Robert Bosch Gmbh | Handwerkzeugmaschine |
| WO2008144616A1 (en) | 2007-05-18 | 2008-11-27 | Heidi Kay | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods |
| US8895610B1 (en) * | 2007-05-18 | 2014-11-25 | Heldi Kay | Platinum (IV) compounds targeting zinc finger domains |
| CA2691047A1 (en) * | 2007-06-18 | 2008-12-24 | Platco Technologies (Proprietary) Limited | Platinum (iv) complexes |
| HUE027443T2 (en) | 2007-09-10 | 2016-10-28 | Boston Biomedical Inc | A novel class of Stat3 pathway inhibitors and tumor stem cell inhibitors |
| WO2010067335A1 (en) | 2008-12-12 | 2010-06-17 | Platco Technologies (Proprietary) Limited | Platinum (iv) complexes for use in the treatment of proliferative diseases such as cancer |
| WO2011160063A2 (en) | 2010-06-18 | 2011-12-22 | Myriad Genetics, Inc. | Methods and materials for assessing loss of heterozygosity |
| ES2704303T3 (es) | 2010-08-24 | 2019-03-15 | Dana Farber Cancer Inst Inc | Procedimientos para la predicción de una respuesta contra el cáncer |
| CA2839210A1 (en) | 2011-06-17 | 2012-12-20 | Myriad Genetics, Inc. | Methods and materials for assessing allelic imbalance |
| RU2491936C2 (ru) * | 2011-07-11 | 2013-09-10 | Борис Николаевич Анисимов | Способ комплексного лечения больных паразитарными заболеваниями |
| EP3660161B1 (en) | 2011-12-21 | 2024-07-31 | Myriad Genetics, Inc. | Methods and materials for assessing loss of heterozygosity |
| EP3415915B1 (en) | 2012-02-23 | 2024-10-23 | Children's Medical Center Corporation | Methods for predicting response to parp inhibitors |
| CA2867434C (en) | 2012-06-07 | 2021-10-12 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
| US10308986B2 (en) | 2013-03-14 | 2019-06-04 | Children's Medical Center Corporation | Cancer diagnosis, treatment selection and treatment |
| AU2014248007B2 (en) | 2013-04-05 | 2020-03-26 | Myriad Genetics, Inc. | Methods and materials for assessing homologous recombination deficiency |
| WO2014198140A1 (zh) * | 2013-06-13 | 2014-12-18 | 上海医药工业研究院 | 一种铂（ⅱ）配合物、其制备方法、药物组合物及应用 |
| WO2015013565A1 (en) * | 2013-07-25 | 2015-01-29 | Nemucore Medical Innovations, Inc. | Platinum derivatives for hydrophobic formulations |
| EP4023765A1 (en) | 2013-12-09 | 2022-07-06 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
| ES2800673T3 (es) | 2014-08-15 | 2021-01-04 | Myriad Genetics Inc | Métodos y materiales para evaluar una deficiencia de recombinación homóloga |
| CN108697093A (zh) | 2015-06-19 | 2018-10-23 | 新纳特产品公司 | 含卡铂的组合物及其用途 |
| AU2016279099B2 (en) | 2015-06-19 | 2021-09-23 | Syn-Nat Products Enterprise LLC | Pharmaceutical composition of carboplatin based co-crystals and use thereof |
| EP3297640A4 (en) | 2015-06-25 | 2019-01-02 | Syn-Nat Products Enterprise LLC | Pharmaceutical co-crystal composition and use thereof |
| US11299469B2 (en) | 2016-11-29 | 2022-04-12 | Sumitomo Dainippon Pharma Oncology, Inc. | Naphthofuran derivatives, preparation, and methods of use thereof |
| EP3714881A4 (en) | 2017-11-21 | 2021-09-01 | Medoncare Pharmaceutical Co., Ltd | COMBINATION PRODUCT INCLUDING DICYCLOPLATIN, ITS PREPARATION PROCESS AND ITS USE |
| CN112175014B (zh) * | 2020-10-10 | 2021-08-20 | 中国药科大学 | 一种一氧化氮供体型四价铂衍生物、制备方法及其医药用途 |
| EP4141127B1 (en) | 2021-08-30 | 2024-10-09 | Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln | Method for assessing homologous recombination deficiency in ovarian cancer cells |
| WO2024063828A1 (en) | 2022-09-21 | 2024-03-28 | Oracle International Corporation | Expert-optimal correlation: contamination factor identification for unsupervised anomaly detection |
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| US4177263A (en) * | 1972-02-28 | 1979-12-04 | Research Corporation | Anti-animal tumor method |
| GB1432563A (en) | 1972-04-10 | 1976-04-22 | Rustenburg Platinum Mines Ltd | Platinum- co-ordination compounds |
| GR851932B (enExample) * | 1984-08-14 | 1985-12-13 | Engelhard Corp | |
| JPS6296A (ja) * | 1985-03-06 | 1987-01-06 | Sumitomo Pharmaceut Co Ltd | 脂溶性白金（２）錯体 |
| JPH01156989A (ja) * | 1987-09-25 | 1989-06-20 | Ss Pharmaceut Co Ltd | 新規白金錯体 |
| EP0328274B1 (en) * | 1988-02-02 | 1994-10-19 | Johnson Matthey, Inc., | Pt (IV) complexes |
| JP3520367B2 (ja) * | 1994-12-22 | 2004-04-19 | 独立行政法人産業技術総合研究所 | 白金ニトロアンミン系錯体の製造方法 |
| AU4842996A (en) * | 1995-02-28 | 1996-09-18 | Yoshinori Kidani | Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same |
| US5922689A (en) * | 1995-09-11 | 1999-07-13 | Unitech Pharmaceuticals, Inc. | Cisplatin analogs for cancer treatment |
| US5849790A (en) * | 1995-11-17 | 1998-12-15 | The University Of South Florida | (Mono) ethylenediaminenitroplatinum (IV) complexes with ligands of oxides of nitrogen as possible anti-tumor agents |
| US6145688A (en) * | 1996-07-17 | 2000-11-14 | Smith; James C. | Closure device for containers |
| US5977393A (en) | 1997-11-21 | 1999-11-02 | California Institute Of Technology | Schiff base derivatives of ruthenium and osmium olefin metathesis catalysts |
| KR100246722B1 (ko) * | 1997-12-30 | 2000-04-01 | 박호군 | 경구용 백금 착화합물 항암제 및 그 제조방법 |
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| EP1146869A2 (en) * | 1999-01-27 | 2001-10-24 | University Of South Florida | Inhibition of stat3 signal transduction for human cancer therapy |
| US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
| US7033597B2 (en) * | 2000-10-13 | 2006-04-25 | Université de Lausanne | Intracellular delivery of biological effectors |
| EP1345956A2 (en) | 2000-10-13 | 2003-09-24 | University of Lausanne | Intracellular delivery of biological effectors by novel transporter peptide sequences |
| US7638122B2 (en) * | 2003-03-07 | 2009-12-29 | University Of South Florida | Stat3 antagonists and their use as vaccines against cancer |
| US7754684B2 (en) | 2003-06-11 | 2010-07-13 | Access Pharmaceuticals, Inc. | Macromolecular platinum chelates |
| DE602004015811D1 (de) | 2003-08-13 | 2008-09-25 | Univ South Florida | Verfahren zur inhibierung der proliferation von tumorzellen, bei dem platinkomplexe eingesetzt werden |
| US20050288365A1 (en) | 2004-01-06 | 2005-12-29 | Heidi Kay | Platinum complexes and methods for inhibiting tumor cell proliferation |
| JP2008519859A (ja) | 2004-11-10 | 2008-06-12 | ユニバーシティー オブ サウス フロリダ | 標的化した薬物送達のための白金錯体 |
| US20100190180A1 (en) | 2005-07-06 | 2010-07-29 | Heidi Kay | Materials and Methods for Screening, Diagnosis and Prognosis of Conditions Associated With Stat Protein Expression |
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- 2004-08-13 AT AT04781131T patent/ATE453653T1/de not_active IP Right Cessation
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- 2004-08-13 CA CA002535762A patent/CA2535762A1/en not_active Abandoned
- 2004-08-13 CA CA002535584A patent/CA2535584A1/en not_active Abandoned
- 2004-08-13 AT AT04809566T patent/ATE404574T1/de not_active IP Right Cessation
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2011
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10766915B2 (en) | 2013-03-15 | 2020-09-08 | Sherri Ann McFARLAND | Metal-based coordination complexes as photodynamic compounds and their use |
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| AU2011202386A1 (en) | 2011-06-09 |
| EP1664070B1 (en) | 2008-08-13 |
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| US7763585B2 (en) | 2010-07-27 |
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| US7759510B2 (en) | 2010-07-20 |
| EP1675864B1 (en) | 2009-12-30 |
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| US7238372B2 (en) | 2007-07-03 |
| WO2005023824A2 (en) | 2005-03-17 |
| ATE404574T1 (de) | 2008-08-15 |
| JP2007502301A (ja) | 2007-02-08 |
| WO2005016946A3 (en) | 2005-09-29 |
| DE602004015811D1 (de) | 2008-09-25 |
| JP2007502777A (ja) | 2007-02-15 |
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| US20050074502A1 (en) | 2005-04-07 |
| AU2004270655B2 (en) | 2011-03-24 |
| WO2005016946A2 (en) | 2005-02-24 |
| US8247445B2 (en) | 2012-08-21 |
| US8598230B2 (en) | 2013-12-03 |
| US20100310645A1 (en) | 2010-12-09 |
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