JP2006525368A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006525368A5 JP2006525368A5 JP2006514250A JP2006514250A JP2006525368A5 JP 2006525368 A5 JP2006525368 A5 JP 2006525368A5 JP 2006514250 A JP2006514250 A JP 2006514250A JP 2006514250 A JP2006514250 A JP 2006514250A JP 2006525368 A5 JP2006525368 A5 JP 2006525368A5
- Authority
- JP
- Japan
- Prior art keywords
- ligand
- lipid
- alkyl
- independently
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003446 ligand Substances 0.000 claims 4
- 150000002632 lipids Chemical class 0.000 claims 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 4
- PORPENFLTBBHSG-MGBGTMOVSA-N 1,2-dihexadecanoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCCC PORPENFLTBBHSG-MGBGTMOVSA-N 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 229910052697 platinum Inorganic materials 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000002993 cycloalkylene group Chemical group 0.000 claims 1
- 150000004985 diamines Chemical class 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46756703P | 2003-05-02 | 2003-05-02 | |
| PCT/US2004/013727 WO2004098524A2 (en) | 2003-05-02 | 2004-05-03 | Lipid platinum complexes and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006525368A JP2006525368A (ja) | 2006-11-09 |
| JP2006525368A5 true JP2006525368A5 (enExample) | 2007-06-14 |
Family
ID=33435089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006514250A Pending JP2006525368A (ja) | 2003-05-02 | 2004-05-03 | 脂質白金錯体およびその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070160656A1 (enExample) |
| EP (1) | EP1622585A4 (enExample) |
| JP (1) | JP2006525368A (enExample) |
| AU (1) | AU2004235781A1 (enExample) |
| CA (1) | CA2524478A1 (enExample) |
| WO (1) | WO2004098524A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080050425A1 (en) * | 2003-05-20 | 2008-02-28 | Jonathan Lewis | Combination Chemotherapy Comprising 5-Fluorouracil or a Derivative Thereof and a Liposomal Platinum Complex |
| WO2004105747A1 (en) * | 2003-05-20 | 2004-12-09 | Aronex Pharmaceuticals, Inc | Combination chemotherapy comprising capecitabine and a liposomal platinum complex |
| AU2005228410A1 (en) | 2004-03-29 | 2005-10-13 | University Of South Florida | Effective treatment of tumors and cancer with triciribine and related compounds |
| US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
| US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
| GR20060100144A (el) * | 2006-03-03 | 2007-10-17 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene | |
| WO2008070136A1 (en) * | 2006-12-06 | 2008-06-12 | University Of South Florida | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
| EP2123258A1 (en) * | 2008-05-23 | 2009-11-25 | Liplasome Pharma A/S | Liposomes for drug delivery |
| AU2010255391C1 (en) * | 2009-06-03 | 2016-10-27 | Sequessome Technology Holdings Limited | Formulations for the treatment of deep tissue pain |
| SG185722A1 (en) | 2010-06-04 | 2013-01-30 | Univ Ohio | Phosphaplatins and their use for treatment of cancers |
| GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
| CN103665050B (zh) * | 2013-08-29 | 2016-04-27 | 西北工业大学 | 一种苯基咪唑邻菲罗啉竹红菌素铂配合物及其制备方法 |
| WO2017001625A1 (en) | 2015-06-30 | 2017-01-05 | Sequessome Technology Holdings Limited | Multiphasic compositions |
| CN105481902B (zh) * | 2015-12-03 | 2017-12-05 | 昆明贵金属研究所 | 以磷酸二氢根为轴向配体的铂(iv)抗癌化合物 |
| CN113453667A (zh) * | 2018-11-02 | 2021-09-28 | 利帕克肿瘤学有限责任公司 | 脂质体增强腹腔内化学疗法 |
| WO2021043402A1 (en) * | 2019-09-05 | 2021-03-11 | Vuab Pharma A.S. | New platinum iv complexes with substantially increased antitumor efficacy |
| ES2998498T3 (en) * | 2020-03-10 | 2025-02-20 | Univ Chung Yuan Christian | Liposome composition and preparation method thereof |
| WO2021216849A1 (en) * | 2020-04-22 | 2021-10-28 | Oncovolution, Llc | Peptide platinum complexes and methods of use thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5829957B2 (ja) * | 1977-09-12 | 1983-06-25 | 喜徳 喜谷 | 新規な白金錯体 |
| JPS5622724A (en) * | 1979-08-02 | 1981-03-03 | Asahi Chem Ind Co Ltd | Pharmaceutical preparation of n4-acylcytosine arabinoside |
| EP0113508A1 (en) * | 1982-11-04 | 1984-07-18 | Inco Research & Development Center, Inc. | Hydrophobic platinum compounds and their preparation |
| US5041581A (en) * | 1985-10-18 | 1991-08-20 | The University Of Texas System Board Of Regents | Hydrophobic cis-platinum complexes efficiently incorporated into liposomes |
| US5384127A (en) * | 1985-10-18 | 1995-01-24 | Board Of Regents, The University Of Texas System | Stable liposomal formulations of lipophilic platinum compounds |
| US5117022A (en) * | 1985-10-18 | 1992-05-26 | The Board Of Regents, The University Of Texas System | Hydrophobic cis-platinum complexes efficiently incorporated into liposomes |
| US5698155A (en) * | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| US5902604A (en) * | 1995-06-06 | 1999-05-11 | Board Of Regents, The University Of Texas System | Submicron liposome suspensions obtained from preliposome lyophilizates |
| WO1998024424A1 (en) * | 1996-12-03 | 1998-06-11 | Rijksuniversiteit Utrecht | Cisplatinum comprising pharmaceutical |
| US5843475A (en) * | 1996-12-06 | 1998-12-01 | Board Of Regents, The University Of Texas System | Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes |
| CN1191067C (zh) * | 1997-02-05 | 2005-03-02 | 法玛西雅厄普约翰美国公司 | 高不溶性铂配合物的脂质复合物和脂质体 |
| JP5096657B2 (ja) * | 2000-08-11 | 2012-12-12 | 大日本住友製薬株式会社 | シスプラチン耐性癌治療剤 |
| AU2003258075A1 (en) * | 2002-08-06 | 2004-02-23 | Lyotropic Therapeutics, Inc. | Lipid-drug complexes in reversed liquid and liquid crystalline phases |
-
2004
- 2004-05-03 JP JP2006514250A patent/JP2006525368A/ja active Pending
- 2004-05-03 EP EP04751216A patent/EP1622585A4/en not_active Withdrawn
- 2004-05-03 US US10/555,495 patent/US20070160656A1/en not_active Abandoned
- 2004-05-03 CA CA002524478A patent/CA2524478A1/en not_active Abandoned
- 2004-05-03 WO PCT/US2004/013727 patent/WO2004098524A2/en not_active Ceased
- 2004-05-03 AU AU2004235781A patent/AU2004235781A1/en not_active Abandoned