JP2007500238A - うつ病及びその他の気分障害のために、nmda受容体アンタゴニストと選択的セロトニン再取り込み阻害薬の併用 - Google Patents

うつ病及びその他の気分障害のために、nmda受容体アンタゴニストと選択的セロトニン再取り込み阻害薬の併用 Download PDF

Info

Publication number
JP2007500238A
JP2007500238A JP2006533500A JP2006533500A JP2007500238A JP 2007500238 A JP2007500238 A JP 2007500238A JP 2006533500 A JP2006533500 A JP 2006533500A JP 2006533500 A JP2006533500 A JP 2006533500A JP 2007500238 A JP2007500238 A JP 2007500238A
Authority
JP
Japan
Prior art keywords
administered
per day
ssri
nmda
linear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006533500A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007500238A5 (https=
Inventor
グプタ・サンディープ
サモリスキー・ゲーリー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forest Laboratories LLC
Original Assignee
Forest Laboratories LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forest Laboratories LLC filed Critical Forest Laboratories LLC
Publication of JP2007500238A publication Critical patent/JP2007500238A/ja
Publication of JP2007500238A5 publication Critical patent/JP2007500238A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006533500A 2003-05-27 2004-05-27 うつ病及びその他の気分障害のために、nmda受容体アンタゴニストと選択的セロトニン再取り込み阻害薬の併用 Pending JP2007500238A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47363903P 2003-05-27 2003-05-27
PCT/US2004/016959 WO2005000216A2 (en) 2003-05-27 2004-05-27 Combination of an nmda receptor antagonist and a selective serotonin reuptake inhibitor for the treatment of depression and other mood disorders

Publications (2)

Publication Number Publication Date
JP2007500238A true JP2007500238A (ja) 2007-01-11
JP2007500238A5 JP2007500238A5 (https=) 2009-07-30

Family

ID=33551455

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006533500A Pending JP2007500238A (ja) 2003-05-27 2004-05-27 うつ病及びその他の気分障害のために、nmda受容体アンタゴニストと選択的セロトニン再取り込み阻害薬の併用

Country Status (16)

Country Link
US (2) US20050014743A1 (https=)
EP (2) EP2260844A1 (https=)
JP (1) JP2007500238A (https=)
KR (2) KR20070104480A (https=)
CN (1) CN1794981A (https=)
AU (1) AU2004251636B2 (https=)
CA (1) CA2528622C (https=)
EA (1) EA010430B1 (https=)
IL (1) IL172163A (https=)
IS (1) IS8150A (https=)
MX (1) MXPA05012493A (https=)
NO (1) NO20056134L (https=)
RS (1) RS20050851A (https=)
UA (1) UA80055C2 (https=)
WO (1) WO2005000216A2 (https=)
ZA (1) ZA200509542B (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007531541A (ja) * 2003-07-16 2007-11-08 アラーガン、インコーポレイテッド タイトレーション/コンプライアンスパック
JP2013121956A (ja) * 2011-12-09 2013-06-20 Lab Servier 4−{3−[cis−ヘキサヒドロシクロペンタ[c]ピロール−2(1H)−イル]プロポキシ}ベンズアミドとNMDA受容体アンタゴニストとの新規な組み合わせ、及びそれを含む医薬組成物
JP2015522075A (ja) * 2012-07-12 2015-08-03 ダニエル・シー・ジャヴィット ヒトにおけるうつ病及び精神病の治療のための組成物及び方法
JP2017514871A (ja) * 2014-05-06 2017-06-08 ノースウェスタン ユニバーシティ Nmdar調節化合物の組合せ
JP2021501209A (ja) * 2017-11-01 2021-01-14 コリア リサーチ インスティチュート オブ ケミカル テクノロジー エスシタロプラムを含む微粒球状徐放出注射剤及びその製造方法

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004266057A1 (en) * 2003-08-21 2005-03-03 H.Lundbeck A/S The combination of a serotonin reuptake inhibitor and a glycine transporter type 1 inhibitor for the treatment of depression
AR046314A1 (es) * 2003-11-05 2005-11-30 Merz Pharma Gmbh & Co Kgaa Composiciones que comprenden ciclohexilaminas y aminoadamantanos
TW200531680A (en) * 2004-03-03 2005-10-01 Merz Pharma Gmbh & Co Kgaa Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease
US20060002999A1 (en) * 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
CN101534808A (zh) * 2005-06-27 2009-09-16 拜维尔实验室国际有限公司 丁氨苯丙酮盐的改良释放配制品
WO2007061868A2 (en) * 2005-11-17 2007-05-31 Trustees Of Tufts College Treatment of stereotypic, self-injurious and compulsive behaviors using specific serotonin reuptake inhibitors and antagonists of nmda receptors
US20070141148A1 (en) * 2005-11-30 2007-06-21 Merz Pharma Gmbh & Co. Kgaa Neramexane MR matrix tablet
EP2089383B1 (en) 2006-11-09 2015-09-16 Probiodrug AG 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
US9126987B2 (en) 2006-11-30 2015-09-08 Probiodrug Ag Inhibitors of glutaminyl cyclase
AU2008220785B2 (en) 2007-03-01 2013-02-21 Vivoryon Therapeutics N.V. New use of glutaminyl cyclase inhibitors
JP5667440B2 (ja) 2007-04-18 2015-02-12 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体
KR100769700B1 (ko) * 2007-06-15 2007-10-23 손춘남 배압제거 역류방지 장치
US20110086916A1 (en) * 2007-09-12 2011-04-14 Merz Pharma Gmbh & Co. Kgaa Interval therapy for the treatment of tinnitus
US20090275597A1 (en) * 2008-05-02 2009-11-05 Forest Laboratories Holdings Limited Methods of treating cns disorders
NZ589764A (en) * 2008-05-09 2012-10-26 Univ Emory NMDA receptor antagonists for the treatment of neuropsychiatric disorders
TWI432188B (zh) 2008-12-19 2014-04-01 Merz Pharma Gmbh & Co Kgaa 供治療發炎性皮膚疾病之1-胺基-烷基環己烷衍生物類
MX2011006353A (es) 2008-12-19 2011-07-13 Merz Pharma Gmbh & Co Kgaa Derivados de 1-amino-alquilciclohexano para el tratamiento de enfermedades mediadas por mastocitos.
IT1396556B1 (it) * 2009-02-11 2012-12-14 Serra Uso di memantina per il trattamento di disturbi dell umore
WO2010126527A1 (en) * 2009-05-01 2010-11-04 Forest Laboratories Holdings Limited Methods of treating cns disorders
US20120123166A1 (en) * 2009-06-29 2012-05-17 Merz Pharma Gmbh & Co. Kgaa Method of preparing 1-hydroxy-1,3,3,5,5-pentamethylcyclohexane
JP5934645B2 (ja) 2009-09-11 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体
WO2011107530A2 (en) 2010-03-03 2011-09-09 Probiodrug Ag Novel inhibitors
JP5688745B2 (ja) 2010-03-10 2015-03-25 プロビオドルグ エージー グルタミニルシクラーゼ(qc、ec2.3.2.5)の複素環阻害剤
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
US10583138B2 (en) 2012-07-12 2020-03-10 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
US10576045B2 (en) * 2011-02-16 2020-03-03 Nir Barak Low dosage combinations of fluoxetine and reboxetine for treating obesity
EP2686313B1 (en) 2011-03-16 2016-02-03 Probiodrug AG Benzimidazole derivatives as inhibitors of glutaminyl cyclase
EP2755644A1 (en) * 2011-09-13 2014-07-23 Novartis AG Combinations comprising a s1p receptor modulator
UA107653U (uk) 2012-10-01 2016-06-24 Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" Композиція лікарських засобів для лікування та профілактики поведінкових, психічних та когнітивних розладів
KR101484405B1 (ko) * 2013-08-14 2015-01-19 서울대학교산학협력단 Ninjurin1 결핍 유래의 강박증 예방 또는 치료용 약학적 조성물
ES2882602T3 (es) * 2015-05-18 2021-12-02 Sensorion Azasetrón para usar en el tratamiento de la pérdida auditiva
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001527554A (ja) * 1997-05-07 2001-12-25 アルゴス ファーマシューティカル コーポレーション 抗うつ薬とnmdaレセプター拮抗薬とを組み合わせる神経障害痛の治療用組成物及び治療方法
JP2002511873A (ja) * 1997-06-30 2002-04-16 メルツ ウント コンパニー ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー 1−アミノ−アルキルシクロヘキサンnmda受容体拮抗薬
JP2003516326A (ja) * 1999-12-06 2003-05-13 ハー・ルンドベック・アクチエゼルスカベット セロトニン再取り込み阻害剤及び5−ht2cアンタゴニスト、逆アゴニスト、または半アゴニストの組み合わせ

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES413944A1 (es) * 1972-04-20 1976-06-01 Merz & Co Procedimiento para la preparacion de compuestos de adamen- tano trisustituidos en las posiciones 1,3,5.
DE2856393C2 (de) * 1978-12-27 1983-04-28 Merz + Co GmbH & Co, 6000 Frankfurt Arzneimittel zur Behandlung von Morbus Parkinson
US5366738A (en) * 1982-07-29 1994-11-22 Merck & Co., Inc. Controlled release drug dispersion delivery device
US5811128A (en) * 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US4849222A (en) 1987-03-24 1989-07-18 The Procter & Gamble Company Mixtures for treating hypercholesterolemia
US4904681A (en) * 1987-12-01 1990-02-27 G. D. Searle & Co. D-cycloserine and its prodrugs as cognitive enhancers
JP2670680B2 (ja) 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
US5061721A (en) * 1989-03-15 1991-10-29 G. D. Searle & Co. Composition containing d-cycloserine and d-alanine for memory and learning enhancement or treatment of a cognitive or psychotic disorder
US5506231A (en) 1989-03-31 1996-04-09 The Children's Medical Center Corporation Treatment of aids dementia, myelopathy and blindness
US5334618A (en) * 1991-04-04 1994-08-02 The Children's Medical Center Corporation Method of preventing NMDA receptor-mediated neuronal damage
DE58905637D1 (de) 1989-04-14 1993-10-21 Merz & Co Gmbh & Co Verwendung von Adamantan-Derivaten zur Prävention und Behandlung der cerebralen Ischämie.
US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
US5614560A (en) * 1991-04-04 1997-03-25 Children's Medical Center Corporation Method of preventing NMDA receptor-mediated neuronal damage
US5288502A (en) 1991-10-16 1994-02-22 The University Of Texas System Preparation and uses of multi-phase microspheres
WO1995011010A1 (en) 1993-10-22 1995-04-27 Genentech, Inc. Methods and compositions for microencapsulation of antigens for use as vaccines
US6071966A (en) * 1997-06-30 2000-06-06 Merz + Co. Gmbh & Co. 1-amino-alkylcyclohexane NMDA receptor antagonists
GB9802225D0 (en) * 1998-02-02 1998-04-01 Cerebrus Ltd Chemical compounds
AU771252B2 (en) 1998-07-13 2004-03-18 Nps Pharmaceuticals, Inc. Methods and compounds for treating depression and other disorders
SE9901077D0 (sv) * 1999-03-23 1999-03-23 Astra Ab Novel use
TW593223B (en) 2000-06-20 2004-06-21 Merz Pharma Gmbh & Co Kgaa 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists
EP1471909A4 (en) * 2002-01-16 2007-07-25 Endo Pharmaceuticals Inc PHARMACEUTICAL COMPOSITION AND METHOD FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM
AU2003268026A1 (en) * 2002-07-30 2004-02-16 Peter Migaly Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions
AU2003302147A1 (en) * 2002-12-23 2004-07-14 Osmotica Costa Rica Sociedad Anonima Delivery device containing venlafaxine and memantine and use method thereof
AR043467A1 (es) * 2003-03-05 2005-07-27 Osmotica Argentina S A Combinacion de drogas para la disfuncion motora en la enfermedad de parkinson
EP1734920A2 (en) * 2004-02-13 2006-12-27 Neuromolecular Inc. Combination of a nmda receptor antagonist and an mao-inhibitor or a gadph-inhibitor for the treatment of psychiatric conditions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001527554A (ja) * 1997-05-07 2001-12-25 アルゴス ファーマシューティカル コーポレーション 抗うつ薬とnmdaレセプター拮抗薬とを組み合わせる神経障害痛の治療用組成物及び治療方法
JP2002511873A (ja) * 1997-06-30 2002-04-16 メルツ ウント コンパニー ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー 1−アミノ−アルキルシクロヘキサンnmda受容体拮抗薬
JP2003516326A (ja) * 1999-12-06 2003-05-13 ハー・ルンドベック・アクチエゼルスカベット セロトニン再取り込み阻害剤及び5−ht2cアンタゴニスト、逆アゴニスト、または半アゴニストの組み合わせ

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007531541A (ja) * 2003-07-16 2007-11-08 アラーガン、インコーポレイテッド タイトレーション/コンプライアンスパック
JP2013121956A (ja) * 2011-12-09 2013-06-20 Lab Servier 4−{3−[cis−ヘキサヒドロシクロペンタ[c]ピロール−2(1H)−イル]プロポキシ}ベンズアミドとNMDA受容体アンタゴニストとの新規な組み合わせ、及びそれを含む医薬組成物
JP2015522075A (ja) * 2012-07-12 2015-08-03 ダニエル・シー・ジャヴィット ヒトにおけるうつ病及び精神病の治療のための組成物及び方法
JP2017514871A (ja) * 2014-05-06 2017-06-08 ノースウェスタン ユニバーシティ Nmdar調節化合物の組合せ
JP2020138973A (ja) * 2014-05-06 2020-09-03 ノースウェスタン ユニバーシティ Nmdar調節化合物の組合せ
JP2021501209A (ja) * 2017-11-01 2021-01-14 コリア リサーチ インスティチュート オブ ケミカル テクノロジー エスシタロプラムを含む微粒球状徐放出注射剤及びその製造方法
JP7266220B2 (ja) 2017-11-01 2023-04-28 コリア リサーチ インスティチュート オブ ケミカル テクノロジー エスシタロプラムを含む微粒球状徐放出注射剤及びその製造方法

Also Published As

Publication number Publication date
CA2528622A1 (en) 2005-01-06
NO20056134L (no) 2006-02-27
ZA200509542B (en) 2007-03-28
UA80055C2 (en) 2007-08-10
EA200501867A1 (ru) 2006-06-30
KR20070104480A (ko) 2007-10-25
EP2260844A1 (en) 2010-12-15
IS8150A (is) 2005-11-25
US20100076073A1 (en) 2010-03-25
EA010430B1 (ru) 2008-08-29
WO2005000216A8 (en) 2005-12-22
MXPA05012493A (es) 2006-05-25
WO2005000216A2 (en) 2005-01-06
RS20050851A (sr) 2008-04-04
AU2004251636A1 (en) 2005-01-06
CN1794981A (zh) 2006-06-28
CA2528622C (en) 2010-08-03
EP1631274A4 (en) 2007-03-28
US20050014743A1 (en) 2005-01-20
EP1631274A2 (en) 2006-03-08
IL172163A (en) 2012-01-31
WO2005000216A3 (en) 2005-11-10
AU2004251636B2 (en) 2006-11-09
KR20060030469A (ko) 2006-04-10

Similar Documents

Publication Publication Date Title
JP2007500238A (ja) うつ病及びその他の気分障害のために、nmda受容体アンタゴニストと選択的セロトニン再取り込み阻害薬の併用
Wellington et al. Venlafaxine extended-release: a review of its use in the management of major depression
JP5675650B2 (ja) 向精神薬の働きを向上させるソルビン酸、安息香酸及びその誘導体
JP2019515891A (ja) タンニン酸を含有する組成物及びその使用
JP2010508354A (ja) 広汎性発達障害の処置
JP2007526335A (ja) 焦燥およびその他の行動障害、特にアルツハイマー病に関連する行動障害の治療用1−アミノシクロヘキサン誘導体
JP2024516297A (ja) うつ病の治療のための組成物及び方法
JP2007513052A (ja) セロトニン再取り込み阻害剤およびアゴメラチンの併用。
US20130217615A1 (en) Combination treatment of major depressive disorder
AU2010252740A1 (en) Methods of enhancing selective serotonin reuptake inhibitor effects in mammals
NO334448B1 (no) Farmasøytisk preparat som omfatter modafinil og et antidepressivt middel
US20260083759A1 (en) Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders
US20250032429A1 (en) 2-fluorodeschloroketamine for treatment of depression, including treatment-resistant depression
WO2024050323A1 (en) Ulotaront for the adjuvant treatment of major depressive disorder
MX2014002965A (es) Combinaciones que comprenden un modulador del receptor de s1p.
HK1092056A (en) Combination of an nmda receptor antagonist and a selective serotonin reuptake inhibitor for the treatment of depression and other mood disorders
HK1105362A (en) 1-aminovyclohexane derivatives for the treatment of agitation and other behavioral disorders, especially those associated with alzheimer's disease

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060110

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060111

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090317

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20090612

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20090908

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20091204

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20091204

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100107

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20100402

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20100423

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20100527

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111108

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111114