JP2007308383A - 油中水乳化剤形の皮膚外用剤 - Google Patents
油中水乳化剤形の皮膚外用剤 Download PDFInfo
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- JP2007308383A JP2007308383A JP2006136247A JP2006136247A JP2007308383A JP 2007308383 A JP2007308383 A JP 2007308383A JP 2006136247 A JP2006136247 A JP 2006136247A JP 2006136247 A JP2006136247 A JP 2006136247A JP 2007308383 A JP2007308383 A JP 2007308383A
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- oil
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007308385A (ja) * | 2006-05-16 | 2007-11-29 | Pola Chem Ind Inc | 乳化剤形の皮膚外用剤 |
| JP2007308384A (ja) * | 2006-05-16 | 2007-11-29 | Pola Chem Ind Inc | 乳化剤形の皮膚外用剤 |
| JP2007308381A (ja) * | 2006-05-16 | 2007-11-29 | Pola Chem Ind Inc | 油中水乳化剤形の皮膚外用剤 |
| JP2011195493A (ja) * | 2010-03-19 | 2011-10-06 | Pola Chemical Industries Inc | ヒアルロン酸産生促進因子 |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09249547A (ja) * | 1996-03-18 | 1997-09-22 | Pola Chem Ind Inc | 油中水乳化組成物 |
| JPH1171256A (ja) * | 1997-08-27 | 1999-03-16 | Noevir Co Ltd | 微細エマルション組成物 |
| JPH11116433A (ja) * | 1997-10-14 | 1999-04-27 | Shiseido Co Ltd | 油中水型乳化組成物及び皮膚外用剤 |
| JPH11228343A (ja) * | 1998-02-20 | 1999-08-24 | Kose Corp | 固形状油中水型化粧料 |
| JP2000136114A (ja) * | 1998-10-30 | 2000-05-16 | Pola Chem Ind Inc | クレンジング化粧料 |
| JP2001348310A (ja) * | 2000-06-06 | 2001-12-18 | Kanebo Ltd | 油中水型固形メイクアップ化粧料 |
| JP2001354538A (ja) * | 2000-06-08 | 2001-12-25 | Noevir Co Ltd | 皮膚外用剤 |
| JP2002212028A (ja) * | 2001-01-12 | 2002-07-31 | Shiseido Co Ltd | 油中水型乳化組成物およびこれを用いた乳化化粧料 |
| JP2004059526A (ja) * | 2002-07-30 | 2004-02-26 | Sakamoto Yakuhin Kogyo Co Ltd | 油中水型乳化化粧料 |
| JP2004534068A (ja) * | 2001-06-19 | 2004-11-11 | バイヤースドルフ・アクチエンゲゼルシヤフト | セラミド生合成を増加させる化粧品学的又は皮膚科学的調製物の調製のためのカルニチン及び／又は１種もしくはそれより多いアシル−カルニチンの使用 |
| JP2005206573A (ja) * | 2003-12-22 | 2005-08-04 | Nippon Fine Chem Co Ltd | ジエステル及び油剤、並びに化粧料及び皮膚外用剤 |
-
2006
- 2006-05-16 JP JP2006136247A patent/JP2007308383A/ja active Pending
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09249547A (ja) * | 1996-03-18 | 1997-09-22 | Pola Chem Ind Inc | 油中水乳化組成物 |
| JPH1171256A (ja) * | 1997-08-27 | 1999-03-16 | Noevir Co Ltd | 微細エマルション組成物 |
| JPH11116433A (ja) * | 1997-10-14 | 1999-04-27 | Shiseido Co Ltd | 油中水型乳化組成物及び皮膚外用剤 |
| JPH11228343A (ja) * | 1998-02-20 | 1999-08-24 | Kose Corp | 固形状油中水型化粧料 |
| JP2000136114A (ja) * | 1998-10-30 | 2000-05-16 | Pola Chem Ind Inc | クレンジング化粧料 |
| JP2001348310A (ja) * | 2000-06-06 | 2001-12-18 | Kanebo Ltd | 油中水型固形メイクアップ化粧料 |
| JP2001354538A (ja) * | 2000-06-08 | 2001-12-25 | Noevir Co Ltd | 皮膚外用剤 |
| JP2002212028A (ja) * | 2001-01-12 | 2002-07-31 | Shiseido Co Ltd | 油中水型乳化組成物およびこれを用いた乳化化粧料 |
| JP2004534068A (ja) * | 2001-06-19 | 2004-11-11 | バイヤースドルフ・アクチエンゲゼルシヤフト | セラミド生合成を増加させる化粧品学的又は皮膚科学的調製物の調製のためのカルニチン及び／又は１種もしくはそれより多いアシル−カルニチンの使用 |
| JP2004059526A (ja) * | 2002-07-30 | 2004-02-26 | Sakamoto Yakuhin Kogyo Co Ltd | 油中水型乳化化粧料 |
| JP2005206573A (ja) * | 2003-12-22 | 2005-08-04 | Nippon Fine Chem Co Ltd | ジエステル及び油剤、並びに化粧料及び皮膚外用剤 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007308385A (ja) * | 2006-05-16 | 2007-11-29 | Pola Chem Ind Inc | 乳化剤形の皮膚外用剤 |
| JP2007308384A (ja) * | 2006-05-16 | 2007-11-29 | Pola Chem Ind Inc | 乳化剤形の皮膚外用剤 |
| JP2007308381A (ja) * | 2006-05-16 | 2007-11-29 | Pola Chem Ind Inc | 油中水乳化剤形の皮膚外用剤 |
| JP2011195493A (ja) * | 2010-03-19 | 2011-10-06 | Pola Chemical Industries Inc | ヒアルロン酸産生促進因子 |
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