JP2006528968A - 無水エレトリプタンヘミサルフェートの製造方法 - Google Patents

無水エレトリプタンヘミサルフェートの製造方法 Download PDF

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Publication number
JP2006528968A
JP2006528968A JP2006530682A JP2006530682A JP2006528968A JP 2006528968 A JP2006528968 A JP 2006528968A JP 2006530682 A JP2006530682 A JP 2006530682A JP 2006530682 A JP2006530682 A JP 2006530682A JP 2006528968 A JP2006528968 A JP 2006528968A
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JP
Japan
Prior art keywords
eletriptan
volume
hours
water content
ethyl acetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006530682A
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English (en)
Japanese (ja)
Inventor
フリアン・アランダ−マルティネス
カサリン・ダン
イュルゲン・フリートリッヒ・クラインシュロート
ジュリー・アン・マクレイ
リチャード・アントニー・ストーリー
エレン・ヨハーナ・ヴァイルバハー
Original Assignee
ファイザー インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by ファイザー インコーポレイテッド filed Critical ファイザー インコーポレイテッド
Publication of JP2006528968A publication Critical patent/JP2006528968A/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
JP2006530682A 2003-05-30 2004-05-18 無水エレトリプタンヘミサルフェートの製造方法 Pending JP2006528968A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0312478.1A GB0312478D0 (en) 2003-05-30 2003-05-30 Improved process
PCT/IB2004/001694 WO2004106327A1 (en) 2003-05-30 2004-05-18 Process for the preparation of anhydrous eleptritan hemisulphate

Publications (1)

Publication Number Publication Date
JP2006528968A true JP2006528968A (ja) 2006-12-28

Family

ID=9959072

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006530682A Pending JP2006528968A (ja) 2003-05-30 2004-05-18 無水エレトリプタンヘミサルフェートの製造方法

Country Status (10)

Country Link
EP (1) EP1633739A1 (pt)
JP (1) JP2006528968A (pt)
AR (1) AR044463A1 (pt)
BR (1) BRPI0410841A (pt)
CA (1) CA2527127A1 (pt)
CL (1) CL2004001132A1 (pt)
GB (1) GB0312478D0 (pt)
MX (1) MXPA05012838A (pt)
TW (1) TWI290923B (pt)
WO (1) WO2004106327A1 (pt)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003510318A (ja) * 1999-09-28 2003-03-18 ファイザー・インク 多形塩

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU651637B2 (en) * 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
WO1999001135A1 (en) * 1997-07-03 1999-01-14 Pfizer Limited Pharmaceutical compositions containing eletriptan hemisulphate and caffeine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003510318A (ja) * 1999-09-28 2003-03-18 ファイザー・インク 多形塩

Also Published As

Publication number Publication date
TWI290923B (en) 2007-12-11
GB0312478D0 (en) 2003-07-09
TW200427683A (en) 2004-12-16
CL2004001132A1 (es) 2005-03-18
EP1633739A1 (en) 2006-03-15
AR044463A1 (es) 2005-09-14
BRPI0410841A (pt) 2006-06-27
CA2527127A1 (en) 2004-12-09
WO2004106327A1 (en) 2004-12-09
MXPA05012838A (es) 2006-02-13

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