JP2006525365A5 - - Google Patents
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- Publication number
- JP2006525365A5 JP2006525365A5 JP2006514244A JP2006514244A JP2006525365A5 JP 2006525365 A5 JP2006525365 A5 JP 2006525365A5 JP 2006514244 A JP2006514244 A JP 2006514244A JP 2006514244 A JP2006514244 A JP 2006514244A JP 2006525365 A5 JP2006525365 A5 JP 2006525365A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- allyl
- independently
- groups
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 18
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 10
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 9
- 229910052736 halogen Inorganic materials 0.000 claims 7
- 150000002367 halogens Chemical class 0.000 claims 7
- 125000004438 haloalkoxy group Chemical group 0.000 claims 5
- 125000001188 haloalkyl group Chemical group 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims 1
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 1
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 1
- -1 phenyloxy Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46686803P | 2003-04-30 | 2003-04-30 | |
| PCT/US2004/013701 WO2004099170A2 (en) | 2003-04-30 | 2004-04-30 | Phenyl substituted carboxylic acids as inhibitors of protein tyrosine phosphatase-1b |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006525365A JP2006525365A (ja) | 2006-11-09 |
| JP2006525365A5 true JP2006525365A5 (https=) | 2007-06-21 |
Family
ID=33434989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006514244A Pending JP2006525365A (ja) | 2003-04-30 | 2004-04-30 | フェニル置換カルボン酸 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7524878B2 (https=) |
| EP (1) | EP1620422A2 (https=) |
| JP (1) | JP2006525365A (https=) |
| KR (1) | KR20060006954A (https=) |
| CN (1) | CN1812978A (https=) |
| AU (1) | AU2004236248A1 (https=) |
| BR (1) | BRPI0409916A (https=) |
| CA (1) | CA2524235A1 (https=) |
| EA (1) | EA200501713A1 (https=) |
| MX (1) | MXPA05011536A (https=) |
| NO (1) | NO20055129L (https=) |
| WO (1) | WO2004099170A2 (https=) |
| ZA (1) | ZA200509635B (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2523718A1 (en) | 2003-04-30 | 2004-11-18 | The Institutes For Pharmaceutical Discovery, Llc | Substituted amino carboxylic acids as inhibitors of protein tyrosine phosphatase-1b |
| DK1666473T3 (da) | 2003-09-17 | 2013-03-25 | Ono Pharmaceutical Co | Carboxylsyreforbindelser og medicinske sammensætninger indeholdende samme som aktiv ingrediens |
| US8053598B2 (en) | 2004-05-05 | 2011-11-08 | High Point Pharmaceuticals, Llc | Compounds, their preparation and use |
| DE602005024384D1 (de) | 2004-05-05 | 2010-12-09 | High Point Pharmaceuticals Llc | Neue verbindungen, ihre herstellung und verwendung |
| US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| US7772271B2 (en) | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| EP1771169A1 (en) | 2004-07-14 | 2007-04-11 | PTC Therapeutics, Inc. | Methods for treating hepatitis c |
| US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| JP2008507518A (ja) | 2004-07-22 | 2008-03-13 | ピーティーシー セラピューティクス，インコーポレーテッド | Ｃ型肝炎を治療するためのチエノピリジン |
| AU2005307735A1 (en) | 2004-11-18 | 2006-05-26 | The Institutes For Pharmaceutical Discovery, Llc | Substituted amino acids as protein Tyrosine phosphatase inhibitors |
| AU2005307718A1 (en) * | 2004-11-18 | 2006-05-26 | The Institutes For Pharmaceutical Discovery, Llc | Heterocycle substituted carboxylic acids for the treatment of diabetes |
| EP1836182A2 (en) * | 2004-11-18 | 2007-09-26 | The Institutes for Pharmaceutical Discovery, LLC | Heterocyclylbiphenyl derivates as protein tyrosine phosphatase inhibitors |
| DE102004060542A1 (de) * | 2004-12-16 | 2006-07-06 | Sanofi-Aventis Deutschland Gmbh | Hydroxybiphenyl-Carbonsäuren und Derivate, Verfahren zu deren Herstellung und deren Verwendung |
| WO2006117657A1 (en) * | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Triazolone derivatives as anti-inflammatory agents |
| ES2372617T3 (es) | 2005-06-30 | 2012-01-24 | High Point Pharmaceuticals, Llc | Ácidos fenoxiacéticos como activadores de ppar-delta. |
| JP4324221B2 (ja) | 2005-08-26 | 2009-09-02 | 株式会社医薬分子設計研究所 | Ｐｐａｒアゴニスト活性を有する誘導体 |
| CN103224477A (zh) | 2005-12-22 | 2013-07-31 | 高点制药有限责任公司 | 作为PPAR-δ活化剂的苯氧基乙酸 |
| US7989461B2 (en) | 2005-12-23 | 2011-08-02 | Amgen Inc. | Substituted quinazolinamine compounds for the treatment of cancer |
| US7943612B2 (en) | 2006-03-09 | 2011-05-17 | High Point Pharmaceuticals, Llc | Compounds that modulate PPAR activity, their preparation and use |
| WO2008033934A1 (en) * | 2006-09-13 | 2008-03-20 | The Institutes For Pharmaceutical Discovery, Llc | Substituted heteroaryl carboxylic acid derivatives as ptb-1b inhibitors |
| WO2008033931A1 (en) * | 2006-09-13 | 2008-03-20 | The Institutes For Pharmaceutical Discovery, Llc | Para-xylylene carboxylic acids and isothiazolones useful as protein tyrosine phosphatases (ptps) in particular ptp-ib |
| EP3103791B1 (en) | 2007-06-27 | 2018-01-31 | Merck Sharp & Dohme Corp. | 4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
| WO2009005638A2 (en) | 2007-06-27 | 2009-01-08 | Merck & Co., Inc. | Pyridyl and pyrimidinyl derivatives as histone deacetylase inhibitors |
| AU2008335709A1 (en) * | 2007-12-13 | 2009-06-18 | Amgen Inc. | Gamma secretase modulators |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| MX2012003778A (es) | 2009-09-29 | 2012-06-01 | Glaxo Group Ltd | Compuestos novedosos. |
| DE102009046115A1 (de) | 2009-10-28 | 2011-09-08 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 3-Phenylpropansäuren und ihre Verwendung |
| JP5814031B2 (ja) * | 2010-07-30 | 2015-11-17 | ユー・ディー・シー アイルランド リミテッド | 有機電界発光素子、及びジベンゾチオフェン構造又はジベンゾフラン構造を有する有機電界発光素子用材料 |
| CN102382037B (zh) * | 2010-09-03 | 2016-01-20 | 中国医学科学院药物研究所 | 苯丙酸类化合物及其制法和药物用途 |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
| WO2012076466A2 (de) | 2010-12-07 | 2012-06-14 | Bayer Pharma Aktiengesellschaft | Substituierte 1-benzylcycloalkylcarbonsäuren und ihre verwendung |
| MX2013006768A (es) | 2010-12-23 | 2013-07-22 | Pfizer | Moduladores de receptor de glucagon. |
| HRP20161177T1 (hr) | 2011-02-08 | 2016-11-04 | Pfizer Inc. | Modulator glukagonskog receptora |
| DE102011007272A1 (de) | 2011-04-13 | 2012-10-18 | Bayer Pharma Aktiengesellschaft | Verzweigte 3-Phenylpropionsäure-Derivate und ihre Verwendung |
| US9308190B2 (en) | 2011-06-06 | 2016-04-12 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
| AU2012288493B2 (en) | 2011-07-22 | 2015-08-06 | Pfizer Inc. | Quinolinyl glucagon receptor modulators |
| DE102012208530A1 (de) | 2012-05-22 | 2013-11-28 | Bayer Pharma AG | Substituierte Piperidinoacetamide und ihre Verwendung |
| WO2014209034A1 (en) * | 2013-06-27 | 2014-12-31 | Lg Life Sciences Ltd. | Biaryl derivatives as gpr120 agonists |
| JO3425B1 (ar) | 2013-07-15 | 2019-10-20 | Novartis Ag | مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b |
| US20170119776A1 (en) | 2014-04-03 | 2017-05-04 | Bayer Pharma Aktiengesellschaft | Chiral 2,5-disubstituted cyclopentanecarboxylic acid derivatives and use thereof |
| US20170114049A1 (en) | 2014-04-03 | 2017-04-27 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituted cyclopentane carboxylic acids for the treatment of respiratory tract diseases |
| EP3126339A1 (de) | 2014-04-03 | 2017-02-08 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituierte cyclopentancarbonsäuren und ihre verwendung |
| CN111978319B (zh) | 2014-06-27 | 2023-08-11 | 诺格拉制药有限公司 | 芳基受体调制剂及其制备和使用方法 |
| KR20170098869A (ko) | 2014-12-18 | 2017-08-30 | 바이엘 파마 악티엔게젤샤프트 | 치환된 피리딜-시클로알킬-카르복실산, 그를 함유하는 조성물 및 그의 의학적 용도 |
| US10905667B2 (en) | 2018-07-24 | 2021-02-02 | Bayer Pharma Aktiengesellschaft | Orally administrable modified-release pharmaceutical dosage form |
| WO2023165523A1 (zh) * | 2022-03-01 | 2023-09-07 | 上海璎黎药业有限公司 | 一类芳香环取代的甲氧基衍生物及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4243678A (en) * | 1977-12-30 | 1981-01-06 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Acylhydrocarbylaminoalkanoic acids, compositions and uses |
| JPS59141540A (ja) * | 1983-02-01 | 1984-08-14 | Chisso Corp | 三環カルボン酸エステル誘導体 |
| MY136593A (en) * | 1992-03-19 | 2008-10-31 | Lilly Co Eli | Cyclic peptide antifungal agents and process for preparation thereof |
| US5786325A (en) * | 1995-05-26 | 1998-07-28 | Eli Lilly And Company | Cyclic peptide antifungal agents and methods of making and using |
| EP0893731B1 (en) * | 1997-07-25 | 2004-01-28 | Eastman Kodak Company | Silver halide light sensitive emulsion layer having enhanced photographic sensitivity |
| DE19907904A1 (de) * | 1999-02-24 | 2000-08-31 | Clariant Gmbh | Verfahren zur Herstellung von [1,1':4',1"]-Terphenylverbindungen |
| US6548529B1 (en) | 1999-04-05 | 2003-04-15 | Bristol-Myers Squibb Company | Heterocyclic containing biphenyl aP2 inhibitors and method |
| CA2404226A1 (en) | 2000-03-23 | 2001-09-27 | Takeda Chemical Industries, Ltd. | Furoisoquinoline derivatives, process for producing the same and use thereof |
| JP4105446B2 (ja) * | 2002-02-20 | 2008-06-25 | 富士フイルム株式会社 | 重合性化合物およびそのマトリックスを用いた光学素子 |
-
2004
- 2004-04-30 MX MXPA05011536A patent/MXPA05011536A/es not_active Application Discontinuation
- 2004-04-30 CN CNA2004800184175A patent/CN1812978A/zh active Pending
- 2004-04-30 EP EP04751193A patent/EP1620422A2/en not_active Withdrawn
- 2004-04-30 WO PCT/US2004/013701 patent/WO2004099170A2/en not_active Ceased
- 2004-04-30 JP JP2006514244A patent/JP2006525365A/ja active Pending
- 2004-04-30 EA EA200501713A patent/EA200501713A1/ru unknown
- 2004-04-30 US US10/835,924 patent/US7524878B2/en not_active Expired - Fee Related
- 2004-04-30 CA CA002524235A patent/CA2524235A1/en not_active Abandoned
- 2004-04-30 AU AU2004236248A patent/AU2004236248A1/en not_active Abandoned
- 2004-04-30 BR BRPI0409916-8A patent/BRPI0409916A/pt not_active IP Right Cessation
- 2004-04-30 KR KR1020057020623A patent/KR20060006954A/ko not_active Withdrawn
-
2005
- 2005-11-02 NO NO20055129A patent/NO20055129L/no not_active Application Discontinuation
- 2005-11-29 ZA ZA200509635A patent/ZA200509635B/en unknown
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