JP2006524682A5 - - Google Patents

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Publication number
JP2006524682A5
JP2006524682A5 JP2006507414A JP2006507414A JP2006524682A5 JP 2006524682 A5 JP2006524682 A5 JP 2006524682A5 JP 2006507414 A JP2006507414 A JP 2006507414A JP 2006507414 A JP2006507414 A JP 2006507414A JP 2006524682 A5 JP2006524682 A5 JP 2006524682A5
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JP
Japan
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optionally substituted
compound according
compound
following formula
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JP2006507414A
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English (en)
Japanese (ja)
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JP4960085B2 (ja
JP2006524682A (ja
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Priority claimed from PCT/US2004/008579 external-priority patent/WO2004083235A2/en
Publication of JP2006524682A publication Critical patent/JP2006524682A/ja
Publication of JP2006524682A5 publication Critical patent/JP2006524682A5/ja
Application granted granted Critical
Publication of JP4960085B2 publication Critical patent/JP4960085B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006507414A 2003-03-19 2004-03-19 Ｔｉｅ−２モジュレータと使用方法 Expired - Fee Related JP4960085B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45656503P 2003-03-19 2003-03-19
US60/456,565 2003-03-19
PCT/US2004/008579 WO2004083235A2 (en) 2003-03-19 2004-03-19 Tie-2 modulators and methods of use

Publications (3)

Publication Number Publication Date
JP2006524682A JP2006524682A (ja) 2006-11-02
JP2006524682A5 true JP2006524682A5 (enExample) 2007-05-24
JP4960085B2 JP4960085B2 (ja) 2012-06-27

Family

ID=33030100

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006507414A Expired - Fee Related JP4960085B2 (ja) 2003-03-19 2004-03-19 Ｔｉｅ−２モジュレータと使用方法

Country Status (6)

Country Link
US (1) US8013156B2 (enExample)
EP (1) EP1608373A4 (enExample)
JP (1) JP4960085B2 (enExample)
AU (1) AU2004221812B2 (enExample)
CA (1) CA2517291C (enExample)
WO (1) WO2004083235A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050124625A1 (en) * 2003-10-21 2005-06-09 Salvati Mark E. Piperazine derivatives and their use as modulators of nuclear hormone receptor function
MX2007006230A (es) 2004-11-30 2007-07-25 Amgen Inc Quinolinas y analogos de quinazolinas y su uso como medicamentos para tratar cancer.
JO2787B1 (en) 2005-04-27 2014-03-15 امجين إنك, Alternative amide derivatives and methods of use
AU2013211455B2 (en) * 2005-09-19 2017-12-07 Neuronascent, Inc. Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration
WO2007035722A2 (en) * 2005-09-19 2007-03-29 Neuronascent, Inc. Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration
WO2008040649A2 (en) * 2006-10-04 2008-04-10 F. Hoffmann-La Roche Ag Pyrazine-2-carboxamide derivatives as cb2 receptor modulators
WO2009158432A2 (en) 2008-06-27 2009-12-30 Amgen Inc. Ang-2 inhibition to treat multiple sclerosis
GB0818241D0 (en) 2008-10-06 2008-11-12 Cancer Res Technology Compounds and their use
TW201920110A (zh) 2009-01-16 2019-06-01 美商艾克塞里克斯公司 包含n-(4-{[6,7-雙(甲氧基)喹啉-4-基]氧基}苯基)-n'-(4-氟苯基)環丙烷-1,1-二甲醯胺之蘋果酸鹽之醫藥組合物及其用途
US8618111B2 (en) * 2010-01-26 2013-12-31 Boehringer Ingelheim International Gmbh 5-alkynyl-pyrimidines
WO2012061337A1 (en) 2010-11-02 2012-05-10 Exelixis, Inc. Fgfr2 modulators
ES2670550T3 (es) 2013-10-14 2018-05-30 Eisai R&D Management Co., Ltd. Derivados de quinolina selectivamente sustituidos
KR101823488B1 (ko) 2013-10-14 2018-01-30 에자이 알앤드디 매니지먼트 가부시키가이샤 선택적으로 치환된 퀴놀린 화합물
TWI704145B (zh) 2015-06-05 2020-09-11 芬蘭商奧利安公司 新醫藥化合物
JP2025528119A (ja) * 2022-08-08 2025-08-26 エイジャックス セラピューティクス， インコーポレイテッド Ｊａｋ２阻害剤としての複素環式アミド及び尿素化合物

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI193974A7 (enExample) * 1973-07-13 1975-01-14 Merck & Co Inc
DE2428030A1 (de) 1974-06-11 1976-01-02 Merck Sharp & Dohme Substituierte thiadiazole und verfahren zu ihrer herstellung
EP0096006A3 (de) 1982-05-28 1984-12-19 Ciba-Geigy Ag 3-(Ureidocyclohexylamino)-propan-1,2-diolderivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen, sowie ihre therapeutische Verwendung
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US4994476A (en) * 1984-10-31 1991-02-19 Bristol-Myers Company Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
IT1191845B (it) * 1986-01-20 1988-03-23 Dompe Farmaceutici Spa Alchiloli derivati farmacologicamente attivi
US4954502A (en) * 1988-06-10 1990-09-04 Bristol-Myers Squibb Company 1-indolyalkyl-4-(substituted-pyridinyl)piperazines
SE8803429D0 (sv) 1988-09-28 1988-09-28 Pharmacia Ab Novel pyridyl- and pyrimidyl derivatives
DE4134467A1 (de) * 1991-10-18 1993-04-22 Thomae Gmbh Dr K Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
SE9202265D0 (sv) 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel- pyridyl and pyrimidylpiperazine derivatives
TW279864B (enExample) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv
US5637592A (en) * 1994-07-12 1997-06-10 Janssen Pharmaceutica N.V. Acyl derivatives of azolones
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones
US5639754A (en) * 1994-07-12 1997-06-17 Janssen Pharmaceutica N.V. Urea and thiourea derivatives of azolones
SK282252B6 (sk) * 1995-01-11 2001-12-03 Samjin Pharmaceutical Co., Ltd. Piperazínové deriváty a farmaceutický prostriedok s ich obsahom
US6391874B1 (en) * 1996-07-13 2002-05-21 Smithkline Beecham Corporation Fused heterocyclic compounds as protein tyrosine kinase inhibitors
GB9713087D0 (en) * 1997-06-20 1997-08-27 Celltech Therapeutics Ltd Chemical compounds
JPH1180119A (ja) 1997-07-15 1999-03-26 Sankyo Co Ltd ピペラジン誘導体
US6462036B1 (en) 1998-11-06 2002-10-08 Basf Aktiengesellschaft Tricyclic pyrazole derivatives
WO2000051999A1 (en) 1999-03-03 2000-09-08 American Home Products Corporation New diazole derivatives as serotonergic agents
CA2374898C (en) 1999-05-21 2009-12-08 Biovitrum Ab Pyrazinyl-piperazine compounds, their use and preparation
SE9901884D0 (sv) * 1999-05-21 1999-05-21 Pharmacia & Upjohn Ab Novel compounds their use and preparation
US6921763B2 (en) * 1999-09-17 2005-07-26 Abbott Laboratories Pyrazolopyrimidines as therapeutic agents
EP1088821A1 (en) * 1999-09-28 2001-04-04 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonamide derivatives
IL153884A0 (en) * 2000-07-20 2003-07-31 Neurogen Corp Capsaicin receptor ligands
JP2004523530A (ja) 2001-01-23 2004-08-05 イーライ・リリー・アンド・カンパニー メラノコルチン受容体アゴニストとしてのピペラジンおよびピペリジン誘導体
WO2002060492A1 (en) * 2001-01-30 2002-08-08 Cytopia Pty Ltd Methods of inhibiting kinases
EP1390034A4 (en) * 2001-04-03 2005-07-13 Merck & Co Inc N-SUBSTITUTED NONARYL HETEROCYCLO AMIDYL-NMDA / NR2B ANTAGONISTS
JP2004536113A (ja) * 2001-07-03 2004-12-02 カイロン コーポレイション チロシンキナーゼおよびセリン／スレオニンキナーゼのインヒビターとしてのインダゾールベンズイミダゾール化合物
DK1531822T3 (da) * 2002-06-12 2009-12-07 Chemocentryx Inc 1-aryl-4-substituerede piperazin derivater til anvendelse som CCR1 antagonister til behandlingen af inflammation og immunforstyrrelser
US7320979B2 (en) * 2003-04-14 2008-01-22 Abbott Gmbh & Co. Kg. N-[(piperazinyl)hetaryl]arylsulfonamide compounds

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