JP2008534541A5 - - Google Patents

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Publication number
JP2008534541A5
JP2008534541A5 JP2008503415A JP2008503415A JP2008534541A5 JP 2008534541 A5 JP2008534541 A5 JP 2008534541A5 JP 2008503415 A JP2008503415 A JP 2008503415A JP 2008503415 A JP2008503415 A JP 2008503415A JP 2008534541 A5 JP2008534541 A5 JP 2008534541A5
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JP
Japan
Prior art keywords
alkyl
aryl
heteroaryl
cycloalkyl
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008503415A
Other languages
English (en)
Japanese (ja)
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JP2008534541A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2006/002769 external-priority patent/WO2006103038A1/en
Publication of JP2008534541A publication Critical patent/JP2008534541A/ja
Publication of JP2008534541A5 publication Critical patent/JP2008534541A5/ja
Pending legal-status Critical Current

Links

JP2008503415A 2005-03-30 2006-03-27 置換１，２−エチレンジアミン、前記化合物を含む薬物、それらの使用及びそれらの製造方法 Pending JP2008534541A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05006939 2005-03-30
PCT/EP2006/002769 WO2006103038A1 (en) 2005-03-30 2006-03-27 Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture

Publications (2)

Publication Number Publication Date
JP2008534541A JP2008534541A (ja) 2008-08-28
JP2008534541A5 true JP2008534541A5 (enExample) 2009-05-14

Family

ID=36545049

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008503415A Pending JP2008534541A (ja) 2005-03-30 2006-03-27 置換１，２−エチレンジアミン、前記化合物を含む薬物、それらの使用及びそれらの製造方法

Country Status (7)

Country Link
US (3) US7713961B2 (enExample)
EP (1) EP1866034A1 (enExample)
JP (1) JP2008534541A (enExample)
AR (1) AR056862A1 (enExample)
CA (1) CA2603404A1 (enExample)
TW (1) TW200716152A (enExample)
WO (1) WO2006103038A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2603404A1 (en) * 2005-03-30 2006-10-05 Boehringer Ingelheim International Gmbh Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture
JP2009503027A (ja) * 2005-08-03 2009-01-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アルツハイマー病ｉｉの治療のための置換エタン−１，２−ジアミン
EP1919861A2 (de) * 2005-08-11 2008-05-14 Boehringer Ingelheim International GmbH Verbindungen zur behandlung der alzheimer erkrankung
US20090042867A1 (en) * 2005-08-11 2009-02-12 Klaus Fuchs Compounds for the treatment of alzheimer's disease
EP1915339A1 (de) * 2005-08-11 2008-04-30 Boehringer Ingelheim International GmbH Inhibitoren der beta-sekretase zur behandlung der alzheimer- erkrankung
CA2618474A1 (en) * 2005-08-11 2007-02-15 Boehringer Ingelheim International Gmbh Compounds for treating alzheimer's disease
JP2012505241A (ja) 2008-10-10 2012-03-01 パーデュー・リサーチ・ファウンデーション アルツハイマー病の治療用組成物
EP2376083A4 (en) 2008-11-20 2012-06-20 Purdue Research Foundation QUINAZOLIN-BASED BACE-1 INHIBITORS AND METHODS OF USE
WO2010065861A2 (en) * 2008-12-05 2010-06-10 Purdue Research Foundation Inhibitors of bace 1 and methods for treating alzheimer's disease
JP2013506713A (ja) * 2009-10-05 2013-02-28 コメンティス，インコーポレーテッド β−セクレターゼ活性を阻害するスルホンアミドピロリジン化合物及びその使用方法
US20140066488A1 (en) * 2012-08-30 2014-03-06 Purdue Research Foundation Inhibitors of Memapsin 2 Cleavage for the Treatment of Alzheimer's Disease
US20240383852A1 (en) * 2021-03-12 2024-11-21 Infex Therapeutics Limited Anti-viral compounds
MX2023014754A (es) 2021-06-18 2024-02-12 Aligos Therapeutics Inc Métodos y composiciones dirigidos a pd-l1.
CN119212987A (zh) 2021-12-16 2024-12-27 安力高医药股份有限公司 用于靶向pd-l1的方法和组合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ184194A3 (en) 1993-08-09 1995-03-15 Lilly Co Eli Aspartylprotease inhibitor and method of identifying thereof
US7087399B1 (en) 1999-05-13 2006-08-08 Scios, Inc. β-secretase and modulation of β-secretase activity
EP1194449B1 (en) 1999-06-28 2010-09-22 Oklahoma Medical Research Foundation Inhibitors of memapsin 2 and use thereof
CA2449948A1 (en) * 2001-06-08 2002-12-19 Elan Pharmaceuticals, Inc. Methods of treating alzheimer's disease
EP1453516A2 (de) 2001-10-17 2004-09-08 Boehringer Ingelheim Pharma GmbH & Co.KG 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren
AU2003206413A1 (en) * 2002-01-04 2003-07-24 Elan Pharmaceuticals, Inc. Substituted amino carboxamides for the treatment of alzheimer's disease
US7763646B2 (en) * 2002-09-27 2010-07-27 Elan Pharmaceuticals, Inc. Compounds for the treatment of alzheimer's disease
DE60329316D1 (de) * 2002-11-12 2009-10-29 Merck & Co Inc Phenylcarboxamide als beta-sekretase-hemmer zur behandlung von alzheimer
US20050090449A1 (en) 2003-05-13 2005-04-28 Boehringer Ingelheim International Gmbh Novel statine derivatives for the treatment of Alzheimer's disease
JP2007516207A (ja) * 2003-06-30 2007-06-21 メルク　エンド　カムパニー　インコーポレーテッド アルツハイマー病の治療のためのＮ−アルキルフェニルカルボキサミドβ−セクレターゼ阻害剤
EP1750719A2 (en) 2004-05-19 2007-02-14 Boehringer Ingelheim International GmbH Treatment of diseases associated with altered level of amyloid beta peptides
WO2005113582A1 (en) 2004-05-22 2005-12-01 Boehringer Ingelheim International Gmbh Substituted ethane-1,2-diamines for the treatment of alzheimer's disease
WO2006050861A2 (en) 2004-11-10 2006-05-18 Boehringer Ingelheim International Gmbh Statine derivatives for the treatment of alzheimer's disease
WO2006050862A1 (en) 2004-11-10 2006-05-18 Boehringer Ingelheim International Gmbh Statine derivatives for the treatment of alzheimer's disease
CA2603404A1 (en) * 2005-03-30 2006-10-05 Boehringer Ingelheim International Gmbh Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture
JP2009503027A (ja) 2005-08-03 2009-01-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アルツハイマー病ｉｉの治療のための置換エタン−１，２−ジアミン
US20090042867A1 (en) 2005-08-11 2009-02-12 Klaus Fuchs Compounds for the treatment of alzheimer's disease

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