JP2006523223A5 - - Google Patents
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- Publication number
- JP2006523223A5 JP2006523223A5 JP2006508795A JP2006508795A JP2006523223A5 JP 2006523223 A5 JP2006523223 A5 JP 2006523223A5 JP 2006508795 A JP2006508795 A JP 2006508795A JP 2006508795 A JP2006508795 A JP 2006508795A JP 2006523223 A5 JP2006523223 A5 JP 2006523223A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- alkoxy
- halogen
- substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052736 halogen Inorganic materials 0.000 claims 12
- 150000002367 halogens Chemical class 0.000 claims 12
- 125000001424 substituent group Chemical group 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 125000004093 cyano group Chemical group *C#N 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 5
- 150000002431 hydrogen Chemical class 0.000 claims 4
- 208000010877 cognitive disease Diseases 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 3
- 208000028698 Cognitive impairment Diseases 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 201000000980 schizophrenia Diseases 0.000 claims 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 102000014415 Muscarinic acetylcholine receptor Human genes 0.000 claims 1
- 108050003473 Muscarinic acetylcholine receptor Proteins 0.000 claims 1
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical group C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 claims 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 208000027061 mild cognitive impairment Diseases 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45691103P | 2003-03-21 | 2003-03-21 | |
| PCT/US2004/005234 WO2004094363A1 (en) | 2003-03-21 | 2004-03-12 | Muscarinic agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006523223A JP2006523223A (ja) | 2006-10-12 |
| JP2006523223A5 true JP2006523223A5 (enExample) | 2007-04-12 |
Family
ID=33310663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006508795A Pending JP2006523223A (ja) | 2003-03-21 | 2004-03-12 | ムスカリン性アゴニスト |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7378447B2 (enExample) |
| EP (1) | EP1608617B1 (enExample) |
| JP (1) | JP2006523223A (enExample) |
| CA (1) | CA2518700A1 (enExample) |
| ES (1) | ES2405055T3 (enExample) |
| WO (1) | WO2004094363A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2880885B1 (fr) * | 2005-01-14 | 2009-01-30 | Merck Sante Soc Par Actions Si | Derives d'acide phenylbenzoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique |
| BR112012024815A2 (pt) | 2010-03-29 | 2017-04-11 | Basf Se | imunoderivados fungicidas |
| EP2746277A1 (en) | 2012-12-19 | 2014-06-25 | Basf Se | Fungicidal imidazolyl and triazolyl compounds |
| CN103420865B (zh) * | 2013-08-27 | 2015-08-26 | 罗梅 | 一种手性酰胺晶体化合物的制备及合成方法 |
| GB201616839D0 (en) * | 2016-10-04 | 2016-11-16 | Takeda Pharmaceutical Company Limited | Therapeutic compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1582197A (en) * | 1996-01-22 | 1997-08-11 | Eli Lilly And Company | Combinatorial process for preparing substituted indane libraries |
| US6211364B1 (en) * | 1997-01-22 | 2001-04-03 | Eli Lilly And Company | Process for preparing indane-like compounds |
| CA2297906A1 (en) | 1997-07-22 | 1999-02-04 | Bret Eugene Huff | Pharmaceutical compounds |
| JP2001220375A (ja) * | 1999-11-30 | 2001-08-14 | Fujisawa Pharmaceut Co Ltd | 新規アミド化合物 |
-
2004
- 2004-03-12 EP EP04720317A patent/EP1608617B1/en not_active Expired - Lifetime
- 2004-03-12 US US10/546,906 patent/US7378447B2/en not_active Expired - Fee Related
- 2004-03-12 ES ES04720317T patent/ES2405055T3/es not_active Expired - Lifetime
- 2004-03-12 CA CA002518700A patent/CA2518700A1/en not_active Abandoned
- 2004-03-12 WO PCT/US2004/005234 patent/WO2004094363A1/en not_active Ceased
- 2004-03-12 JP JP2006508795A patent/JP2006523223A/ja active Pending